• 대한원격탐사학회:학술대회논문집
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• 대한원격탐사학회 2003년도 Proceedings of ACRS 2003 ISRS
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• pp.1415-1417
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• 2003

In this study, as the passing of a year, the changes of tidal flat area in Seohan Bay, North Korea was monitored through using Landsat ETM Data and the ancient topological map. The map to present tidal flat distribution characteristic based on the ancient topographical map (1918) was constructed as GIS DB. In addition, a tidal flat distribution map was estimated by using the satellite images with unsupervised classification method. Even though it is difficult to approach to study area, it was possible to gain the data and to monitor the change of the coast tidal flat by comparing to area change yielded.

• 한국생물정보학회:학술대회논문집
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• 한국생물정보시스템생물학회 2004년도 The 3rd Annual Conference for The Korean Society for Bioinformatics Association of Asian Societies for Bioinformatics 2004 Symposium
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• pp.265-271
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• 2004

The interaction network of protein -protein plays an important role to understand the various biological functions of cells. Currently, the high -throughput experimental techniques (two -dimensional gel electrophoresis, mass spectroscopy, yeast two -hybrid assay) provide us with the vast amount of data for protein-protein interaction at the proteome scale. In order to recognize the role of each protein in their network, the efficient bioinformatical and computational analysis methods are required. We propose a systematic and mathematical method which can analyze the protein -protein interaction network rigorously and enable us to capture the biological and physical essence of a topological character and stability of protein -protein network, and sensitivity of each protein along the biological pathway of their network. We set up a Laplacian matrix of spectral graph theory based on the protein-protein network of yeast proteome, and perform an eigenvalue analysis and apply a perturbation method on a Laplacian matrix, which result in recognizing the center of protein cluster, the identity of hub proteins around it and their relative sensitivities. Identifying the topology of protein -protein network via a Laplacian matrix, we can recognize the important relation between the biological pathway of yeast proteome and the formalism of master equation. The results of our systematic and mathematical analysis agree well with the experimental findings of yeast proteome. The biological function and meaning of each protein cluster can be explained easily. Our rigorous analysis method is robust for understanding various kinds of networks whether they are biological, social, economical...etc

• 한국생산제조학회지
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• 제21권5호
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• pp.797-804
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• 2012

Magnesium has a long tradition of use as a lightweight material in the field of automotive industry. This paper presents the design optimization process of Mg armrest frame to minimize its weight by replacing the steel frame. formerly, the analysis of steel armrest frame was peformed to determine the design specifications for Mg armrest frame. The initial design of Mg armrest frame was carried out by topological optimization technique. After six types of design variables and four types of response variables were defined, DOE(Design of Experiment) and RSM (Response Surface Method) were applied in order to measure sensitivity of design variables and realize optimization through regression model. After design optimization, the weight of the optimized Mg armrest frame was reduced by about 3% compared to the initial design of the Mg frame and was decreased by 41.7% in comparison with that of the steel frame. Some prototypical armrest frames were also made by die casting process and tested. The results were satisfying for its design specifications.

• 한국조경학회지
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• 제32권6호
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• pp.36-51
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• 2005

The purpose of this thesis is to analyse modem urbanization process and the morphological transformation of the urban tissues in Kunsan between the you 1899 and 2001, The method of this study is to investigate the transformation process of morphological elements such as plot structure, building layout, building facades, land use, exterior space structure and their use, with actual field surveys, the analysis of land registration maps in 1912, and various topological map. Morphological analysis on modern Kunsan is progressed by three steps-typo-morphological analysis of urban tissue in old-town area, interpretation of morphological process, and transformation process, of morphological structure in Japanese concession in view of plots system. As a result, it is found that there is cyclical relationship among the morphological transformation processes of morphological elements, plots, buildings, land-uses, and access space to buildings. From the view of town plan change, the period of restoration of war damage in 1950s and compressive growing period in 1960s have important meaning in the morphological process of old-town area. Particularly the first building plan and layout type together with plot form and structure is acted as the main factor to decide the subsequent plot transformation system, exterior space system and the particular streetscape in Kunsan.

• 한국전산구조공학회논문집
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• 제15권1호
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• pp.33-42
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• 2002

본 연구에서는 3차원 곡면의 매개변수식 기하 표현법과 계층적/관계형 자료 구조를 이용하여 3차원 터널을 자동으로 모델링할 수 있는 방안을 제시한다. 매개변수식 기하 표현법과 계층적/관계형 자료 구조의 이용은 3차원 터널 표현의 일반화와 확장성을 제공하며 해석을 위한 터널 구조의 특성을 정확하게 처리할 수 있게 한다. 그리고 터널 곡면의 곡률 특징을 이용하여 2차원 요소망 생성 알고리즘을 사용하여 3차원 요소망을 자동으로 생성할 수 있다.

• Asian Pacific Journal of Cancer Prevention
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• 제13권12호
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• pp.6375-6378
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• 2012

Background: Small-cell lung cancer (also known as SCLC) is an aggressive form and untreated patients generally die within about 3 months. To obtain further insight into mechanism underlying malignancy with this cancer, an miRNA synergistic regulatory network was constructed and analyzed in the present study. Method: A miRNA microarray dataset was downloaded from the NCBI GEO database (GSE27435). A total of 546 miRNAs were identified to be expressed in SCLC cells. Then a miRNA synergistic network was constructed, and the included miRNAs mapped to the network. Topology analysis was also performed to analyze the properties of the synergistic network. Consequently, we could identified constitutive modules. Further, common target genes of each module were identified with CFinder. Finally, enrichment analysis was performed for target genes. Results: In this study, a miRNA synergistic network with 464 miRNAs and 2981 edges was constructed. According to the topology analysis, the topological properties between the networks constructed by LC related miRNAs and LC unrelated miRNAs were significantly different. Moreover, a module cilque0 could be identified in our network using CFinder. The module included three miRNAs (hsa-let-7c, hsa-let-7b and hsa-let-7d). In addition, several genes were found which were predicted to be common targets of cilque0. The enrichment analysis demonstrated that these target genes were enriched in MAPK signaling pathways. Conclusions: Although limitations exist in the current data, the results uncovered here are important for understanding the key roles of miRNAs in SCLC. However, further validation is required since our results were based on microarray data derived from a small sample size.

• 한국자동차공학회논문집
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• 제10권3호
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• pp.151-158
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• 2002

Automotive engineers involved in a new car project use various CAD systems that are chosen based on work requirements. For example, engineers in Hyundai Motors are using Pro/Designer and Alias fur the style design, but they use CATIA to design parts and assemblies, ANSYS for FEM analysis, and Pro/Engineer to design engines. Because they use different CAD systems, they have difficulties in collaborative design. Data, which contains errors, is transferred between CAD systems. It is difficult to find out such errors in a large CAD model. An evaluation method for CAD models has been developed in this study. This diagnosis tool analyses a STEP or an IGES file generated from a CAD system, and produces a quantitative error report. The tool has been tested with actual data sets. This paper proposes an algorithm that produces mathematical error values of entities of IGES models that have geometrical data, and entities of STEP models that have topological data, and inspects every part off model. To develop this system, we have used the OpenCASCADE kernel, which is an open source kernel developed by Matra Datavision of France.

• 품질경영학회지
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• 제37권3호
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• pp.39-53
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• 2009

This paper suggests a new process structuring method, which we call process modularization, for decomposing and grouping activities in a process. Above all, we propose the concept of a module that is a group of activities positioned on the same flow before and after control constructs. Since activities in a module are relatively strongly interrelated with one another, it is important to take into consideration of these together. A design structure matrix (DSM) is used to structure the process because it has a lot of advantages in process modeling and analysis. We developed two algorithms: the restricted topological sorting (RTS) algorithm for ordering activities and the module finding (MF) algorithm for detecting modules in a process, which utilize the DSM. The suggested approach enables a firm's manager to design and analyze the process effectively. We also developed a supporting tool to accelerate the progress of process modularization. The supporting tool aids the process manager in finding the module and understanding the process structure easily. An illustrative example is addressed to show operations of the suggested approach.

• 한국실내디자인학회논문집
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• 제13권2호
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• pp.29-37
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• 2004

This study analyze the architectural space in the aspect of the 'Raumplan' and 'Plan Libre'. These concepts based on the 'Raumplan versus Plan Libre' exhibition in Delft University, Netherlands. It is generally agreed that the concept of 'Plan Libre' in connection with Le Corbusie architecture and 'Raumplan' related to Adolf Loos's works. that exhibition contents was focused an extent of modem architecture. But, These concepts continually influence contemporary architecture and offer diverse vision in architecture. Therefore, this study focused on the analysis that look for common element in the space through the case study and space element connection in change of the values, technical growth. This Paper reveals that Adolf Loos's Raumplan is similar to Louis I. Kahn's 'Room' concept and Ando Tadao's centrifugal space composition method In the dwelling architecture. And the concept 'Plan Libre': non-definitive formal system and the elements : column, free form screening wall is revived as formal application of 3 dimension composition in architecture. and transfer lots, void, and linear space in Rem Koolhaas's urban design projects. These aspects is so called topology. This topological concept is an attempt in view of the space connection state rather than formative viewpoint.

• 한국수자원학회:학술대회논문집
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• 한국수자원학회 2004년도 학술발표회
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• pp.1167-1172
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• 2004

최근 급격한 인구증가와 산업화, 도시화로 포장지역의 증가에 따른 불투수지역의 증가로 유역의 유출 특성의 변화를 유발시키고 있다. 도시화 유역의 효율적인 관리를 위해서는 유역에 내할 정확할 지형인자 및 수문 관련 인자들을 추출해야 한다. 본 연구에서는 GIS와 XP-SWMM을 이용하여 안양천유역의 유출분석을 수행하였다. 안양천 유역을 GIS를 이용하여 13개의 소유역으로 분할하고 입력자료를 구축하였다. GIS를 이용하여 지형도로부터 각각의 소유역에 대하여 면적, 경사도, 폭과 하천 각 구간의 길이, 경사도를 얻었고, 토지이용도와 토양도로부터 불투수비, 토지이용상태, 침투능에 내한 정보를 얻었다. 여기서 얻은 결과를 토대로, 안양천 유역에 도시유출 모형인 XP-SWMM을 적용하여 도시화유역의 관리방안을 제시하였다.