• Proceedings of the KSRS Conference
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• 2003.11a
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• pp.1415-1417
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• 2003

In this study, as the passing of a year, the changes of tidal flat area in Seohan Bay, North Korea was monitored through using Landsat ETM Data and the ancient topological map. The map to present tidal flat distribution characteristic based on the ancient topographical map (1918) was constructed as GIS DB. In addition, a tidal flat distribution map was estimated by using the satellite images with unsupervised classification method. Even though it is difficult to approach to study area, it was possible to gain the data and to monitor the change of the coast tidal flat by comparing to area change yielded.

• Proceedings of the Korean Society for Bioinformatics Conference
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• 2004.11a
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• pp.265-271
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• 2004

The interaction network of protein -protein plays an important role to understand the various biological functions of cells. Currently, the high -throughput experimental techniques (two -dimensional gel electrophoresis, mass spectroscopy, yeast two -hybrid assay) provide us with the vast amount of data for protein-protein interaction at the proteome scale. In order to recognize the role of each protein in their network, the efficient bioinformatical and computational analysis methods are required. We propose a systematic and mathematical method which can analyze the protein -protein interaction network rigorously and enable us to capture the biological and physical essence of a topological character and stability of protein -protein network, and sensitivity of each protein along the biological pathway of their network. We set up a Laplacian matrix of spectral graph theory based on the protein-protein network of yeast proteome, and perform an eigenvalue analysis and apply a perturbation method on a Laplacian matrix, which result in recognizing the center of protein cluster, the identity of hub proteins around it and their relative sensitivities. Identifying the topology of protein -protein network via a Laplacian matrix, we can recognize the important relation between the biological pathway of yeast proteome and the formalism of master equation. The results of our systematic and mathematical analysis agree well with the experimental findings of yeast proteome. The biological function and meaning of each protein cluster can be explained easily. Our rigorous analysis method is robust for understanding various kinds of networks whether they are biological, social, economical...etc

• Journal of the Korean Society of Manufacturing Technology Engineers
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• v.21 no.5
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• pp.797-804
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• 2012

Magnesium has a long tradition of use as a lightweight material in the field of automotive industry. This paper presents the design optimization process of Mg armrest frame to minimize its weight by replacing the steel frame. formerly, the analysis of steel armrest frame was peformed to determine the design specifications for Mg armrest frame. The initial design of Mg armrest frame was carried out by topological optimization technique. After six types of design variables and four types of response variables were defined, DOE(Design of Experiment) and RSM (Response Surface Method) were applied in order to measure sensitivity of design variables and realize optimization through regression model. After design optimization, the weight of the optimized Mg armrest frame was reduced by about 3% compared to the initial design of the Mg frame and was decreased by 41.7% in comparison with that of the steel frame. Some prototypical armrest frames were also made by die casting process and tested. The results were satisfying for its design specifications.

• Journal of the Korean Institute of Landscape Architecture
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• v.32 no.6 s.107
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• pp.36-51
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• 2005

The purpose of this thesis is to analyse modem urbanization process and the morphological transformation of the urban tissues in Kunsan between the you 1899 and 2001, The method of this study is to investigate the transformation process of morphological elements such as plot structure, building layout, building facades, land use, exterior space structure and their use, with actual field surveys, the analysis of land registration maps in 1912, and various topological map. Morphological analysis on modern Kunsan is progressed by three steps-typo-morphological analysis of urban tissue in old-town area, interpretation of morphological process, and transformation process, of morphological structure in Japanese concession in view of plots system. As a result, it is found that there is cyclical relationship among the morphological transformation processes of morphological elements, plots, buildings, land-uses, and access space to buildings. From the view of town plan change, the period of restoration of war damage in 1950s and compressive growing period in 1960s have important meaning in the morphological process of old-town area. Particularly the first building plan and layout type together with plot form and structure is acted as the main factor to decide the subsequent plot transformation system, exterior space system and the particular streetscape in Kunsan.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.15 no.1
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• pp.33-42
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• 2002

A method of automatic 3D tunnel modeling is proposed. The proposed method used the parametric representation of geometry and a hierarchical and relational data structure. These two bases provide the generalization and extension for 3D tunnel modeling. Especially, these two fundamentals ion the basis iota representing the characteristics of the tunnel structure for analysis. The constant-curvature characteristic is exploited to generate 3D mesh on the tunnel surface. This is attributed to the advantage that any 2D automatic mesh generation algorithm can be applied to 3D mesh modeling.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.12
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• pp.6375-6378
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• 2012

Background: Small-cell lung cancer (also known as SCLC) is an aggressive form and untreated patients generally die within about 3 months. To obtain further insight into mechanism underlying malignancy with this cancer, an miRNA synergistic regulatory network was constructed and analyzed in the present study. Method: A miRNA microarray dataset was downloaded from the NCBI GEO database (GSE27435). A total of 546 miRNAs were identified to be expressed in SCLC cells. Then a miRNA synergistic network was constructed, and the included miRNAs mapped to the network. Topology analysis was also performed to analyze the properties of the synergistic network. Consequently, we could identified constitutive modules. Further, common target genes of each module were identified with CFinder. Finally, enrichment analysis was performed for target genes. Results: In this study, a miRNA synergistic network with 464 miRNAs and 2981 edges was constructed. According to the topology analysis, the topological properties between the networks constructed by LC related miRNAs and LC unrelated miRNAs were significantly different. Moreover, a module cilque0 could be identified in our network using CFinder. The module included three miRNAs (hsa-let-7c, hsa-let-7b and hsa-let-7d). In addition, several genes were found which were predicted to be common targets of cilque0. The enrichment analysis demonstrated that these target genes were enriched in MAPK signaling pathways. Conclusions: Although limitations exist in the current data, the results uncovered here are important for understanding the key roles of miRNAs in SCLC. However, further validation is required since our results were based on microarray data derived from a small sample size.

• Transactions of the Korean Society of Automotive Engineers
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• v.10 no.3
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• pp.151-158
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• 2002

Automotive engineers involved in a new car project use various CAD systems that are chosen based on work requirements. For example, engineers in Hyundai Motors are using Pro/Designer and Alias fur the style design, but they use CATIA to design parts and assemblies, ANSYS for FEM analysis, and Pro/Engineer to design engines. Because they use different CAD systems, they have difficulties in collaborative design. Data, which contains errors, is transferred between CAD systems. It is difficult to find out such errors in a large CAD model. An evaluation method for CAD models has been developed in this study. This diagnosis tool analyses a STEP or an IGES file generated from a CAD system, and produces a quantitative error report. The tool has been tested with actual data sets. This paper proposes an algorithm that produces mathematical error values of entities of IGES models that have geometrical data, and entities of STEP models that have topological data, and inspects every part off model. To develop this system, we have used the OpenCASCADE kernel, which is an open source kernel developed by Matra Datavision of France.

• Journal of Korean Society for Quality Management
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• v.37 no.3
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• pp.39-53
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• 2009

This paper suggests a new process structuring method, which we call process modularization, for decomposing and grouping activities in a process. Above all, we propose the concept of a module that is a group of activities positioned on the same flow before and after control constructs. Since activities in a module are relatively strongly interrelated with one another, it is important to take into consideration of these together. A design structure matrix (DSM) is used to structure the process because it has a lot of advantages in process modeling and analysis. We developed two algorithms: the restricted topological sorting (RTS) algorithm for ordering activities and the module finding (MF) algorithm for detecting modules in a process, which utilize the DSM. The suggested approach enables a firm's manager to design and analyze the process effectively. We also developed a supporting tool to accelerate the progress of process modularization. The supporting tool aids the process manager in finding the module and understanding the process structure easily. An illustrative example is addressed to show operations of the suggested approach.

• Korean Institute of Interior Design Journal
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• v.13 no.2
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• pp.29-37
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• 2004

This study analyze the architectural space in the aspect of the 'Raumplan' and 'Plan Libre'. These concepts based on the 'Raumplan versus Plan Libre' exhibition in Delft University, Netherlands. It is generally agreed that the concept of 'Plan Libre' in connection with Le Corbusie architecture and 'Raumplan' related to Adolf Loos's works. that exhibition contents was focused an extent of modem architecture. But, These concepts continually influence contemporary architecture and offer diverse vision in architecture. Therefore, this study focused on the analysis that look for common element in the space through the case study and space element connection in change of the values, technical growth. This Paper reveals that Adolf Loos's Raumplan is similar to Louis I. Kahn's 'Room' concept and Ando Tadao's centrifugal space composition method In the dwelling architecture. And the concept 'Plan Libre': non-definitive formal system and the elements : column, free form screening wall is revived as formal application of 3 dimension composition in architecture. and transfer lots, void, and linear space in Rem Koolhaas's urban design projects. These aspects is so called topology. This topological concept is an attempt in view of the space connection state rather than formative viewpoint.

• Proceedings of the Korea Water Resources Association Conference
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• 2004.05b
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• pp.1167-1172
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• 2004

Recently, runoff characteristics of urban area are changing because of the increase of impervious area by rapid increasing of population and industrialization, urbanization. It needs to extract the accurate topological and hydrological parameters of watersheds in order to manage water resource efficiently. In this paper, rainfall-runoff analysis in An-Yang stream basin was made using GIS(Geographic Information System) and XP-SWMM(Export Stormwater and Wastewater Management Model). The basin was divided into 13 sub-basins using GIS. The area, slope, width of each subcatchment and length, slop of each stream reach were acquired from topographic maps, and imperviousness rate, land use types, infiltration capacities of each subcatchment from land use maps and soil maps using GIS. We gave th runoff management method of urbanization area us ing XP-SWMM.