• Journal of Korean Academy of Oral and Maxillofacial Radiology
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• v.24 no.1
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• pp.47-55
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• 1994

Post operative maxillary cyst may arise after the surgical treatment for maxillary sinusitis with the symtoms of swelling, pain, and pus discharge in the buccal region. It is examined by Waters' view, panoramic view and other intraoral radiographs, but quite variable radiologically. Most of the cyst is seen round or ovoid shape radiolucency, destruction, expansion and thinning of the lateral wall or posterior wall, and roots of the adjacent teeth may be resorbed. We studied about 117 cases of the post operative maxillary cysts which diagnosed in department of oral and maxillofacial radiology, Seoul National University Hospital. We analyzed and obtained following results. 1. These cysts occured more frequently in male than in female and the incidence is highest in the 4th and 5th decade. 2. Initial radical operation of maxillary sinus were performed mainly between the age of 10 and 45 years, and about 60% of the patients were 15 to 25 years. 3. Pain and swelling on buccal area, pus discharge, and toothache are most chief compaints, seven cases were found at routine examination without symtoms. 4. Most of these cysts were unilocular with smooth and well-defined border. 5. The majority of the cysts occurred in the anterolateral wall of maxillary sinus. 6. Dental changes of the lesional area were loss of lamina dura and root resorption, but about 55% were not changed.

• The Korea Journal of Herbology
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• v.22 no.1
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• pp.81-87
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• 2007

Objectives: Angelicae Dahuricae Radix (Baek-Ji in Korean, BJ) is well known to be used as a medicine for cold, headache, supraorbital pain, nasal congestion, and toothache. Little is understood about the roles of BJ in the cytokine and chemokine secretion by immune cells. This study was designed to find out the effects of BJ on the cytokine and chemokine secretion in human mast cells (HMC). Methods : We treated BJ according to consistency on HMC and measured cytokines and chemokines levels using flow cytometry CBA system. Results: In BJ treated group. the expression of interferon-inducible protein 10 (IP-l0), monocyte chemoattractant protein-1 (MCP-1), chemokine (C-X-C motif) ligand 9 (MIG), and interleukin 10 (IL-l0) levels were decreased significantly and chemokine (C-C motif) ligand 5 (RANTES), IL-8, $interferone-{\gamma}$ ($IFN-{\gamma}$), and tumor necrosis factor alpha (TNF-a) were decreased significantly. Conclusion : The results of this experiment supposed that the treatment of BJ will ameliorate the secreting levels of some chemokines or cytokines such as IP-10, MCP-1, MIG, IL-10, RANTES, IL-8, $IFN-{\gamma}$, and TNF-a.

• Journal of Oral Medicine and Pain
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• v.24 no.2
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• pp.107-115
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• 1999

The author studied the prevalence and sites of orofacial pain during the latest 6 months, and psychologic symptoms under the emotional stress through SCL-90-R in thirty-five dental students(nineteen men and sixteen women) of school of Dentistry, Chonbuk National University. 26 students(74.3%), 12 men and 14 women, experienced the orofacial pain; headache, toothache, facial & buccal pain, TMJ pain and intraoral pain were occurred in 51.4%, 37.1%, 25.7%, 17.1% and 17.1% respectively. In psychological scores in before-, during- and after examination, there was no significant difference between men and women. On the other hand, when these scores were compared each other in one group with orofacial pain experience and the other group without pain experience, the former showed significantly higher values in somatization, depression, hostility, and paranoid ideation dimension before examination, interpersonal sensitivity and anxiety dimension during examination, and somatization dimension after examination than those of the later group(P<0.05). The changes of psychologic symptoms in before-, during-, and after examination were observed in one group with pain experience and the other group without pain experience, respectively; in the former group the significantly higher values of anxiety dimension in during examination than after examination, and the significantly higher values of interpersonal sensitivity dimension in before examination than after examination(P<0.05) were evaluated.

• Advances in Traditional Medicine
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• v.10 no.2
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• pp.51-58
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• 2010

Vitex rotundifolia (V. rotundifolia) has been used for treating headache, dizziness, toothache and removal of fever as a traditional medicine in Korea. In the present study, we examined the antioxidant and anti-inflammatory activities of 85% methanol extract of V. rotundifolia. In various radical scavenging assays, V. rotundifolia exhibited strong scavenging effect on 1, 1-diphenyl-2-picrylhydrazyl free radical, superoxide radical, nitric oxide. To elucidate the anti-inflammatory properties of V. rotundifolia, we investigated the inhibition effects of nitric oxide production in IFN-gamma and LPS-stimulated mouse peritoneal macrophages. V. rotundifolia suppressed nitric oxide production, iNOS and COX-2 expression dose-dependently through suppression of NF-$\hat{e}B$ activation without notable cytotoxicity. These findings mean that V. rotundifolia may be beneficial in oxidative stress-mediated inflammatory disorders.

• Journal of Korean society of Dental Hygiene
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• v.16 no.6
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• pp.955-968
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• 2016

Objectives: The purpose of the study was to investigate the oral health behavior according to perceived oral symptoms in the elderly. Methods: The data were obtained from the 6th Korean National Health and Nutrition Examination Survey (2013). Data were analyzed by complex sample frequency t test, one-way ANOVA, ${\chi}^2$ test, and general analysis. The questionnaire consisted of general characteristics of the subjects and perceived oral symptoms. Results: Those who had higher education tended to brush teeth regularly. The use of oral hygiene product was also high in higher educated elderly and higher income. Those with good oral health perception showed regular toothbrushing habit. Those with good chewing and mastication used oral hygiene products. Male tended to have regular dental checkup. Those having spouse, higher income, younger age, regular dental checkup had good chewing ability. Poor oral health perception, toothache, and chewing difficulty were the main cause of dental visit (p<0.05). Conclusions: The elderly with poor perceived oral symptoms showed lower level of oral hygiene care. They tended to visit dental clinics only when they had oral symptoms.

• Journal of Korean society of Dental Hygiene
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• v.15 no.6
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• pp.963-971
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• 2015

Objectives: The purpose of the study is to investigate the relationship between health factor, oral health factor and revalence of depression in Korea elderly by data from the 5th Korea National Health and Nutrition Examination Survey(KNHANES) 2012. Methods: The subjects were 10,938 elderly over 65 years old by rolling survey method and data were extracted from the 5th Korea National Health and Nutrition Examination Survey(KNHANES) 2012. Data of 1,421 elderly were finally selected and analyzed using kstrada. The questionnaire consisted of socio-demographical characteristics of the subjects, health factors, oral health factors and depression. The oral health factors included subjective perception of oral health, alcohol consumption, exercise, smoking, and toothache. Results: Health factors influencing on the prevalence of depression were subjective health(p<0.001), stress(p<0.001), and alcohol consumption(p<0.05). Oral health factors related to the prevalence of depression were subjective oral health(p<0.05), annual dental checkup(p<0.01), and speaking problem(p<0.01). Conclusions: It is necessary to develop the oral health promotion program for the elderly and help them maintain good quality of life and mental health.

• Journal of the korean academy of Pediatric Dentistry
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• v.2 no.1
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• pp.57-66
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• 1975

The study was performed to evaluate the Parent's knowledge and attitudes concerning the dental health of their children. A questionnaire consisting of 17 questions was given to each of the 664 parents by their children who are attending in primary school and was completed by them. The collected information from the questionnaire was analyzed by the visits to dental clinic, age and education. The results obtained from this study are as follows: 1) The more educated parents were more interested to the dental health of children. 2) In the know ledge concerning the dental health of their children, the parents who were more educated and had visited the dental clinic gave the better. responses. 3) There were no clear differences in age groups in the knowledge and attitudes on their children's dental health. 4) The reason for first visiting the dental clinic was dental treatment 43.2%, toothache 35.4%, for the purpose of oral examination 21.2%, and others were 9.2%. 5) 13.1% of the parents who had visited the dental clinic couldn't or didn't follow the recommended treatment because of economic difficulty 53.3%, lack of time 25%, lack of understanding of child's dental needs 18.3%, and other reasons were 3.3%.

• Maxillofacial Plastic and Reconstructive Surgery
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• v.22 no.1
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• pp.110-116
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• 2000

A 61-years old man with diabetes mellitus(DM) was admitted to our hospital, complaining of progressive right periorbital swelling, headache and toothache on the right lower second molar. On the first visit, moderate swelling was noticed from the right periorbital region with exophthalmos and subconjunctival effusion. Intraorally, right lower second molar had a severe periodontal disease and fistular formation on its distal area. From 3 days after hospitalization, the visual acuity of his right eye was gradually worsen and we performed CT scan. CT scan demonstrated an inflammatory change at the right orbit with subperiosteal abscess at the inferior orbital wall, which was extended from the right infratemporal, parapharyngeal and internal pterygoid space. Patient was treated by mean of intraoral(right upper vestibular and retromolar) and extraoral(infraorbital) incision and drainage, massive anti-therapy and DM control. The patient improved gradually and finally was discharged from the hospital, but his visual loss of right side was not recovered.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.33 no.1
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• pp.20-27
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• 2007

Eugenol is commonly used in dentistry for the sedation of toothache, pulpitis, and dental hyperalgesia. This study was performed to investigate the apoptotic effect of eugenol to human osteosarcoma (HOS) cells and the potential use of this compound in osteosarcoma cells. Eugenol showed the apoptotic effect in HOS cells in dose- and time-dependent manner. Fragmentation and condensation of DNA were showed by TUNEL assay, Hemacolor stain and Hoechst stain. In the DNA electrophoresis analysis, cells showed DNA degradation characteristic of apoptosis with a ladder pattern of DNA fragments. Apoptosis-related factors were analyzed by western blotting. Cells treated with eugenol showed caspase-3, PARP, lamin A and DFF-45 cleavage. Eugenol treatment induced caspase-3 cleavage and activation. Cleavages of PARP, DFF-45 and lamin A were accompanied with activation of caspase triggered by eugenol in HOS cells. Though this study needs more investigations, these results suggest that eugenol induce apoptosis via caspase dependent pathway in HOS cells and eugenol may constitute a potential antitumor compound against osteosarcoma cells.

• YAKHAK HOEJI
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• v.56 no.5
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• pp.299-303
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• 2012

Homosyringaldehyde was isolated and identified from the 80% methanol extract of roots of Cynanchum paniculatum. C. paniculatum has been widely used for the treatment of various diseases such as neurasthenia, insomnia, dysmenorrheal and toothache. This compound exerted significant neuroprotective activities against glutamate-induced neurotoxicity in hippocampal HT22 cell line by 37.53% (at the concentration of $100{\mu}M$). We investigated mode of action of this compound. Homosyringaldehyde ($100{\mu}M$) significantly decreased the ROS level and $Ca^{2+}$ concentration in the oxidative stress induced HT22 cells by oxidative glutamate toxicity. Thus, our results suggest that homosyringaldehyde significantly protect HT22 cells against glutamate-induced oxidative stress, via antioxidative activities. As the results, we suggest that homosyringaldehyde may be useful in the treatment of neurogenerative disorders.