• 제목/요약/키워드: Tooth Decay

검색결과 50건 처리시간 0.023초

Plant Extracts Inhibiting Biofilm Formation by Streptococcus mutans without Antibiotic Activity

  • Ham, Youngseok;Kim, Tae-Jong
    • Journal of the Korean Wood Science and Technology
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    • 제46권6호
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    • pp.692-702
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    • 2018
  • Streptococcus mutans causes oral diseases, including tooth decay, by producing a biofilm called plaque. Therefore, inhibition of biofilm formation is essential for maintaining oral health. Plants produce a variety of secondary metabolites, which act as starting sources for the discovery of new bioactive chemicals that inhibit biofilm formation of S. mutans. Previous studies have reported on chemicals with antibiotic activity for the inhibition of biofilm formation by S. mutans. In this study, nine plant extracts from Melonis Pedicellus, Agastachis Herba, Mori Cortex Radicis, Diospyros kaki leaves, Agrimoniae Herba, Polygoni Multiflori Radix, Lycopi Herba, Elsholtziae Herba, and Schizonepetae Spica were screened for the inhibition of biofilm formation from a plant extract library. The water-soluble compounds of the extracts did not affect cell growth but selectively inhibited biofilm formation. These results suggest that the selected plant extracts constitute novel biofilm formation inhibitors, with a novel biological mechanism, for improving oral hygiene.

상수도수 불소투입에 관한 연구 (A Study of Fluoride Injection in Water Supply)

  • 김성순;이양규;김갑진;서성원
    • 상하수도학회지
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    • 제10권4호
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    • pp.73-84
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    • 1996
  • Fluoride was first introduced into the drinking water of residents of Grand Rapids, Michigan in 1945 for the prevention of dental caries. Ever since, growing numbers of communities favor fluoridation. Now, over 7000 communities in the United States are adding F(0.7~1.2ppm) to their drinking water. The most effective to prevent tooth decay is putting lower concentrated fluoride(F, 0.7~1.2ppm) into drinking water. However, exact fluoride injection amount have not been decided, because the research of the fluoride injection effect was insufficient. Therefore, after separating fluoridation and non-fluoridation into public water supplies, we investigated concentration of fluoride, alkalinity, Al, Ca, Mg, evaporation residuals in APT, domestic, commercial area. Then, we decided allowable concentration of fluoride, injection point of fluoride in water supply system, cost effectiveness.

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정수처리과정(淨水處理過程)에서의 잔류불소(殘留弗素)이온 거동(擧動)에 관한 연구(硏究) (A Study on the Behavior of Residual Fluoride in Water Treatment Process)

  • 이택순;문병현;서규태;진홍식
    • 상하수도학회지
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    • 제14권2호
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    • pp.164-173
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    • 2000
  • Fluoridation of drinking water to a level of about 0.8mg/l (below 1.5mg/l) for reducing the incidence of tooth decay is recommended. However, concerns about potential problems of unknown effects and overdosing hinders the fluoridation. This study describes the work performed to obtain information on the behavior of fluoride under various conditions in the process of water fluoridation. Effects of water treatment chemicals, water treatment unit, and water distribution on water fluoridation were investigated at both lab and an actual water treatment plant. Residual fluoride concentration was not affected by lime and chlorine dosage up to 20mg/l. Flocculation with PAC slightly decreased the residual fluoride concentration as PAC dosage increased. Average fluoride concentration of 0.87mg/l at an intake basin was decreased to 0.83mg/l by sedimentation, 0.81mg/l by dual media(sand+anthracite) filtration, and 0.79mg/l by granular activated carbon filtration in the water treatment plant.

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Autofluorescence Loss in Photobleaching for Human Dentin ex vivo

  • Lee, Seunghwan Goldmund;Kim, Minwoo;Jeong, Sunghee;Hwang, Jaejoon;Kim, Jisu;Gourrier, Aurelien;Vial, Jean Claude;Kyhm, Kwangseuk
    • Current Optics and Photonics
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    • 제6권1호
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    • pp.86-91
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    • 2022
  • Two-photon fluorescence microscopy was performed on the enamel-dentin junction area of a human tooth using a femtosecond pulsed laser. We obtained a clear image contrast between the bright dentin and dark tubules with the autofluorescence generated from the endogenous fluorophores in dentin. The autofluorescence shows a broad spectrum due to complex cross links between dentinal collagens, which extend from blue to orange wavelengths (470-590 nm), but a gradual autofluorescence loss in photobleaching was observed for a long-term exposure under strong excitation. For increasing excitation power, we found that two-step decay becomes significant in the spectrally integrated autofluorescence.

수종의 합성 고무탄성재의 성질에 관한 연구 (PHYSICAL PROPERTIES OF VAR10US BRANDS OF ELASTOMERIC CHAINS)

  • 김경호;황충주;성상진
    • 대한치과교정학회지
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    • 제27권6호
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    • pp.943-954
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    • 1997
  • 교정적인 치아이동에 필요한 힘들은 orthodontic wire나 여러 가지 elastic rubber등으로 얻을 수 있다. 이중 교정용 elastic rubber는 환경 변화, 시간 경과, 신장(stretch) 정도에 따라 영구 변형과 힘의 소실(force decay)이 다양하게 나타나므로 적용된 힘을 예측하기 힘든 단점이 있다. 본 연구에서는 임상에서 널리 사용되는 3가지 종류 (Ormco : Generation II Power Chains ; brand A, RMO : Energy-Chain ; brand B, Unitek : AlastiK ; brand C)의 교정용 합성고무탄성재를 실험 환경, 초기 힘의 크기, 고무탄성재의 형태 그리고 신장속도를 달리한 뒤 시간에 따른 잔존 힘의 변화를 비교하였으며, 종류에 따른 특징적인 물리적 성질에 대하여 다음과 같은 결론을 얻었다. 1. 세 종류 모두에서 상온의 공기에 보관된 경우 잔존 힘의 비율이 가장 컸으며 물과 타액 간에는 차이가 없었다. 2. 세 종류 모두에서 24시간 이후로는 초기 힘의 크기에 따른 잔존 힘의 비율에 차이가 없었다. 3. A, B는 filament 유무에 따른 잔존 힘의 비율에 차이가 없었으나 C에서는 filament가 있는 경우 힘의 소실이 더 많았다. 4. 신장속도를 달리하여도 잔존 힘의 비율에는 큰 차이가 없었다. 5. B는 각각의 실험조건에서 A, C보다 상대적으로 잔존 힘의 비율이 높았다.

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녹차 섭취기간에 따른 질병 발현 연구 (A Study of Disease Prevalence According to Green Tea Consumption)

  • 백송남;진현화;이현정;김양하;양정례
    • 한국식품영양과학회지
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    • 제31권5호
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    • pp.856-861
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    • 2002
  • 본 연구는 녹차의 섭취기간에 따른 질병 발현 정도를 조사하기 위하여 경상남도 하동군에 거주하는 주민 92명을 대상으로 설문조사를 통하여 이루어졌다. 조사대상자들의 녹차 섭취기간에 따라 녹차를 마시지 않는 대조군과 10년 미만 녹차 섭취군 및 10년 이상 녹차 섭취군의 3분위로 나누어 녹차의 장기간 섭취가 건강관련 변인과 식습관에 미치는 영향을 분석하였다. 그 결과는 다음과 같다. 조사대상자의 일반적 특성은 전체 대상자 중 남자가 41명, 여자가 51명이었으며, 평균연령은 대조군이 62.0세, 2분위 60.1세, 3분위 57.2세로 나타났다. 건강관련 생활습관으로 음주여부는 1분위에서 45.5%, 2분위 36.1%, 3분위 37.5%가 음주를 하는 것으로 나타나, 녹차를 마시는 집단에서의 음주비율이 낮게 나타났다. 마시는 술의 종류로는 소주가 가장 많은 비중을 차지하였으며, 음주의 빈도는 1, 3분위에서 주 5~6회 마신다가 50%이상, 2분위는 주 1~2회가 53.8%로 가장 많이 차지하였다. 흡연여부는 80%정도가 거의 담배를 피우지 않는 것으로 조사되어 바람직한 흡연행동을 나타내었다. 신체활동정도는 모든 집단이 농사일에 직접 참여함으로써 왕성한 활동정도를 보였으며, 건강보조식품은 잘 섭취하지 않는 것으로 조사되었다. 질병유병률을 조사한 결과, 충치는 1분위 9%, 2분위 27%, 3분위 36%가 충치가 없다고하여 녹차의 장기간 섭취가 충치 예방에 다소간의 영향을 미쳤음을 알 수 있었다. 감기는 각 분위에서 77%, 87%, 76%로 감기를 잘 앓지 않는 것으로 조사되었으나 유의성은 없었다. 골다공증에 관한 문진 결과 29%, 64%, 100%순으로 정상이라고 응답하였다. 그러나 골다공증 검사율이 저조하여 녹차의 효과를 비교하기는 힘들었다. 식습관 점수는 녹차를 장기간 섭취할수록 유의적으로 좋은 점수를 나타내었다. 본 연구의 대상자들은 녹차를 접할 기회가 많고 주로 질병의 예방 및 개선을 목적으로 마시고 있었기에 녹차의 기능성에 대해서 많은 관심과 기대를 보여주고 있었다. 게다가 본 조사의 결과, 녹차의 장기간 음용이 충치, 골다공증과 같은 질병의 예방 및 식습관 향상에 영향을 미침을 알 수 있었고 나아가 녹차의 섭취를 증가시키기 위해서는 차 이외의 다양한 음식과 생활용품으로의 개발이 필요함을 알 수 있었다.

외국인 이주 노동자의 구강건강관리 실태 및 우식경험영구치지수 (A study on oral health state of immigrant workers with DMFT-index)

  • 김주영;정명희
    • 한국치위생학회지
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    • 제7권2호
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    • pp.123-133
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    • 2007
  • This document is about immigrant worker who use counseling office for human rights in the Daegu Gumin Church. We researched their oral health state so that we can understand their situation and support them properly. General characteristics of study subjects, habits related to oral health, the oral examination and treatment clinic, participated in oral heath education program were studied by designed administered questionaire. And decay, filling(treatment teeth), missing tooth(lost teeth by dental-caries)was counted by oral examination, and calculated DMFT-index. This study was done from the July, 9, 2006 to Aug. 8, 2006. In a total of 289 immigrant worker, 77.9% of them were men and 22.1% of them were women. 55.7% of their salary was from 1,000,000 won to 1,500,000 won and most of them were working for a fiber industry. Many of them are living in korea for more then three years. DMFT index for men was 2.77 and for women was 4.06 so average of DMFT index was 3.06. 46.7% of them said that they are healthy in oral health state. The question for having difficulty using dental clinic in korea, 65.1% of them said "it is difficult". First reason was a communication problem and second was time. Most of them didn't have a oral health education but 85.1% of them said that they are looking forward to attending oral health education. Immigrant worker had better DMFT index then that of korean blue color worker. But still it is quite difficult for them using dental clinic in korea also cost. It is necessary to support them properly that medical insurance system, medical facilities of quality, medical insurance subscriber beside, made by their language, manual for them. At once, medical service improvement a policy is necessary for immigrant worker in korea.

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초등학생들의 체중신장지수(WLI)와 치아우식증에 관한 연구 (A Study on the Weight Length Index and Dental Caries of Elementary School Students)

  • 이선미;김송전
    • 한국치위생학회지
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    • 제3권1호
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    • pp.25-43
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    • 2003
  • In Korea, changes in children's diet patterns accelerate their physical growth and development: frequent snacking has been presumed to be a major cause of increasing dental caries. The present study attempts to clarify the relationship between the physical development of growing children and their tooth decay. For this purpose, 632 six-grade children in 4 elementary school located in Urban(Seoul) and Rural(Po-gok, Yang-In) were classified into three groups based on the Weight Length Index(WLI), known to reflect the nutritional conditions of school-age children, and the relationship was analyzed between each group and the variables considered to be related with dental caries. The result is as follows: The average weight and height of the male is $44.88{\pm}10.89$ kg, $148.49{\pm}7.33$ cm and female is $43.35{\pm}9.60$ kg, $149.23{\pm}6.73$ cm, respectively, which are in the similar level with the Korean Physical Standard. The classification of the children by the WLI reveals a relatively high distribution of over-weighted child ren - 212 persons, 335% of the entire population. The DMFT Index was a little high in the rural area(3.15 teeth in urban and 3.31, in rural). Among the groups of children classified by the WLI, the over-weight group have the highest DMFT index(3.69 teeth). The relationship between the frequency of taking in basic nutrients and the DMFT index is also found: the relationship is not evident in case of the foods containing rich calcium, protein, as well as fruits and vegetables. But, in the protein-rich food, higher frequency of its intake means significantly lower DMFT index in the normal-weight group of the urban children. In case of carbohydrate, higher frequency of its intake means significantly higher DMFT index in all the groups of the rural children. The DMFT index has some correlations with the relevant variables: the index has a positive correlation with the frequency of snacking, and a negative correlation with the economic status. That is, the higher the frequency of snacking is, and the lower the economic status is, the higher the DMFT index may be. In the logistic multiple regression analysis conducted with the presence of DMFT as a dependent variable, only the frequency of tooth brushing is turned to be a variable affecting the presence of either decayed, missing, or filled teeth. Based on the above result, the variables affecting the DMFT index are a time spent on eating, frequency of intake of protein and carbohydrate for a week, frequency of snacking, regular dental check-ups, preventive behaviors for oral health(fluoride gargling, tooth brusing after each meal, proper tooth brushing method). These variables have a relationship with the DMFT index, but the degree is somewhat different between the groups classified either by the region or by the WLI. Therefore, appropriate nutrition management should be conducted according to the individual's nutritional conditions when the services like nutritional education are provided based on the closely-examined characteristics of each target group. And, at the same time, oral health education should be strengthened, and its importance should also be emphasized so that people can pay attention to their own oral health.

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Quantitative Analysis of Tooth Mineral Content by High Resolution Micro-computed Tomography

  • Song, Dae-Sung;Kim, Jung-Woo;Hwang, Hee-Su;Oh, Sin-Hye;Song, Ju Han;Kim, Il-Shin;Hwang, Yun-Chan;Koh, Jeong-Tae
    • International Journal of Oral Biology
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    • 제42권4호
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    • pp.155-161
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    • 2017
  • Teeth and bones are highly mineralized tissues containing inorganic minerals such as calcium phosphate, and a growing number of evidences show that their mineral content is associated with many diseases. Although the quantification of mineral contents by micro-computed tomography(micro- CT) has been used in diagnosis and evaluation for treating bone diseases, its application for teeth diseases has not been well established. In this study, we attempted to estimate a usefulness of a high-resolution micro-CT in analysis of human teeth. The teeth were scanned by using the Skyscan 1172 micro-CT. In order to measure tooth mineral content, beam hardening effect of the machine was corrected with a radiopaque iodine-containing substance, iodoacetamide. Under the maximum resolution of $6.6{\mu}m$, X-ray densities in teeth and hydroxyapatite standards were obtained with Hounsfield unit (HU), and they were then converted to an absolute mineral concentration by a CT Analyzer software. In enamel layer of cusp area, the mean mineral concentration was about $2.14mg/mm^3$ and there was a constant mineral concentration gradient from the enamel surface to the dentinoenamel junction. In the dentin of middle 1/3 of tooth, the mean mineral concentration was approximately $1.27mg/mm^3$ and there was a constant mineral concentration gradient from the outer of root to the pulp side, ranging from 1.3 to $1.06mg/mm^3$. In decay region of dentin, the mineral content was gradually decreased from the intact inner side to the decayed surface. These results suggest that high-resolution micro-CT can be as a useful tool for non-invasive measurement of mineral concentration in teeth.

Anticaries Effect of Ethanol Extract of Terminalia chebula

  • Lee, Moonkyung;Hwang, Young Sun
    • 치위생과학회지
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    • 제21권2호
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    • pp.119-126
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    • 2021
  • Background: Dental caries is mainly composed of various cellular components and is deposited around the tooth surface and gums, causing a number of periodontal diseases. Streptococcus mutans is commonly found in the human oral cavity and is a significant contributor to tooth decay. The use of antibacterial ingredients in oral hygiene products has demonstrated usefulness in the management of dental caries. This study investigated the anticaries effect of the ethanol extract of Terminalia chebula (EETC) against S. mutans and their cytotoxicity to gingival epithelial cells. Methods: The EETC was prepared from T. chebula fruit using ethanol extraction. Disk diffusion, minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC), and colony forming unit (CFU) were analyzed to investigate the antimicrobial activity of the EETC. Glucan formation was measured using the filtrate of the bacterial culture medium and sucrose. Gene expression was analyzed using reverse transcription-polymerase chain reaction (RT-PCR). Cytotoxicity was analyzed via the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide assay. Results: The antibacterial activity of the EETC was explored using disc diffusion and CFU measurements. The MIC and MBC of the EETC were 10 and 20 ㎍/ml, respectively. EETC treatment decreased insoluble glucan formation by S. mutans enzymes and also resulted in reduced glycosyltransferase B (gtf B), gtf C, gtf D, and fructosyltransferase (ftf), expressions on RT-PCR. In addition, at effective antibacterial concentrations, EETC treatment was not cytotoxic to gingival epithelial cells. Conclusion: These results demonstrate that the EETC is an effective anticaries ingredient with low cytotoxicity to gingival epithelial cells. The EETC may be useful in antibacterial oral hygiene products for the management of dental caries.