• Smart Structures and Systems
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• v.31 no.6
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• pp.545-559
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• 2023

Nanoparticle strips (NPS) are widely used as external reinforcers for two-way reinforced concrete slabs. However, the Structural Health Monitoring (SHM) of these slabs is a very important issue and was evaluated in this study. This study has been done analytically and numerically to optimize the placement of sensors. The properties of slabs and carbon nanotubes as composite sheets were considered isotopic and orthotropic, respectively. The nonlinear Finite Element Method (FEM) approach and suitable optimal placement of sensor approach were developed as a new MATLAB toolbox called DECOMAC by the authors of this paper. The Suitable multi-objective function was considered in optimized processes based on distributed ECOMAC method. Some common concrete slabs in construction with different aspect ratios were considered as case studies. The dimension and distance of nano strips in retrofitting process were selected according to building codes. The results of Optimal Sensor Placement (OSP) by DECOMAC algorithm on un-retrofitted and retrofitted slabs were compared. The statistical analysis according to the Mann-Whitney criteria shows that there is a significant difference between them (mean P-value = 0.61).

• Interdisciplinary Bio Central
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• v.3 no.1
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• pp.3.1-3.16
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• 2011

Investigation of the genetic functions in complex biological systems is a challenging step in recent year. Hence, several valuable and interesting research projects have been developed with novel ideas to find out the unknown functions of genes or proteins. To validate the applicability of their novel ideas, various approaches are built up. To date, the most promising and commonly used approach for discovering the target proteins from biological system using small molecule is well known a forward chemical genetics which is considered to be more convenient than the classical genetics. Although, the forward chemical genetics consists of the three basic components, the target identification is the most challenging step to chemical biology researchers. Hence, the diverse target identification methods have been developed and adopted to disclose the small molecule bound protein. Herein, in this review, we briefly described the first two parts chemical toolbox and screening, and then the target identifications in forward chemical genetics are thoroughly described along with the illustrative real example case study. In the tabular form, the different biological active small molecules which are the successful examples of target identifications are accounted in this research review.

• The Transactions of the Korean Institute of Electrical Engineers A
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• v.48 no.10
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• pp.1287-1292
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• 1999

In large-scale systems, we frequently encounter the time-delay and the uncertainty, and these should be considered in the design of controller because these are the source of the degradation of the system performance and instability of system. In this paper, we consider the robust stability of the linear large scale systems with the uncertainties and the time-delays. The considered uncertainties are both structured uncertainty and the unstructured uncertainty. Also, the considered time-delays are time-varying having finite time derivative limits. Based on the Lyapunov theorem and the linear matrix inequality(LMI) technique, we present two sufficient conditions that guarantee the robust stability of the system. The conditions are expressed as the LMI forms which can be easily checked their feasibility by using the well-known LMI control toolbox. Finally, we show by two examples that our results are less conservative than the previous results.

• Korean Journal of Computational Design and Engineering
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• v.14 no.3
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• pp.207-216
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• 2009

Modern engineering design problems involve complexity of disciplinary coupling and difficulty of problem formulation. Multidisciplinary design optimization can overcome the complexity and design optimization software or frameworks can lessen the difficulty. Recently, a growing number of new multidisciplinary design optimization techniques have been proposed. However, each technique has its own pros and cons and it is hard to predict a priori which technique is more efficient than others for a specific problem. In this study, a software system has been developed to directly solve MDO problems with minimal input required. Since the system is based on MATLAB, it can exploit the optimization toolbox which is already developed and proven to be effective and robust. The framework is devised to change an MDO technique to another as the optimization goes on and it is called a reconfigurable MDO framework. Several numerical examples are shown to prove the validity of the reconfiguration idea and its effectiveness.

• Journal of Construction Engineering and Project Management
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• v.7 no.3
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• pp.39-55
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• 2017

Preeminent performance of construction industry are unattainable with poor productivity resulting in time and cost over runs. Enhancement in productivity cannot be achieved without identifying and analyzing factors that adversely affect productivity. The objective therefore is to propose a productivity analysis model to quantify the probability of effect of factors influencing productivity by using fuzzy logic incorporated with relative importance index method, for various types of construction projects. To achieve this objective, a questionnaire survey was carried out targeting respondents of Indian construction industry, from four distinct projects, namely, residential, commercial, infrastructure and industrial projects. Based on questionnaire administered, the relative importance and ranks of factors demonstrated using relative importance index method. Probability assessment model to analyze productivity was then developed by using Fuzzy Logic Toolbox of MATLAB. The applicability of the proposed model was tested in seven construction projects and the probability of impact of factors on productivity evaluated. The results of application of model in the construction firms infers that the most contributing factor groups for most of the projects were discerned to be manpower, motivation and time group.

• International Journal of Fuzzy Logic and Intelligent Systems
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• v.12 no.3
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• pp.187-192
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• 2012

This paper is concerned with stabilization problem of continuous-time Takagi-Sugeno fuzzy systems. To do this, the stabilization problem is investigated based on the new fuzzy Lyapunov functions (NFLFs). The NFLFs depend on not only the fuzzy weighting functions but also their first-time derivatives. The stabilization conditions are derived in terms of linear matrix inequalities (LMIs) which can be solved easily by the Matlab LMI Toolbox. Simulation examples are given to illustrate the effectiveness of this method.

• Journal of Power Electronics
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• v.10 no.6
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• pp.595-603
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• 2010

In this paper, teaching in a "switching converter (SC) design" course using problem-based learning (PBL) with dynamicbehavior- model simulation, given at Lunghwa University of Science and Technology (LHU), Taiwan, is proposed. The devised methodology encourages students to design and implement the SCs and regulate the controller's parameters in frequency domain by using 'sisitool' ('bode') in the MATLAB toolbox. The environment of PBL with converter characterization modeling and simulation reforms the learning outcome greatly and speeds up the teaching-learning process. To qualify and evaluate the learning achievements, a hands-on project cooperated with the continuous assessment approach is performed to modulate the teaching pace and learning direction in good time. Results from surveys conducted in the end of the course provided valuable opinions and suggestions for assessing and improving the learning effect of the proposed course successively. Positive feedbacks from the examinations, homework, questionnaires, and the answers to the lecturer's quizzes during class indicated that the presented pedagogy supplied more helpfulness to students in comparisons with conventional teaching paradigm, their learning accomplishments were better than expected as well.

• International Journal of Fluid Machinery and Systems
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• v.8 no.2
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• pp.113-123
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• 2015

The efficiency of the ventilation system is a key point for durable and reliable electric generators. The design of such system requires a detailed understanding of the air flow in the generator. Computational fluid dynamics (CFD) has the potential to resolve the lack of information in this field. The present work analyses the air flow inside a generator model. The model is designed using a CFD-based approach, and manufactured by taking into consideration the experimental and numerical requirements and limitations. The emphasis is on the possibility to accurately predict and experimentally measure the flow distribution inside the stator channels. A major part of the work is focused on the design of an intake and a fan that gives an evenly distributed flow with a high flow rate. The intake also serves as an accurate flowmeter. Experimental results are presented, of the total volume flow rate, the total pressure and velocity distributions. Steady-state CFD simulations are performed using the FOAM-extend CFD toolbox. The simulations are based on the multiple rotating reference frames method. The results from the frozen rotor and mixing plane rotor-stator coupling approaches are compared. It is shown that the fan design provides a sufficient flow rate for the stator channels, which is not the case without the fan or with a previous fan design. The detailed experimental and numerical results show an excellent agreement, proving that the results reliable.

• Korean Journal of Remote Sensing
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• v.31 no.1
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• pp.1-9
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• 2015

Mobility and cloud platform have become the dominant paradigm to develop web services dealing with huge and diverse digital contents for scientific solution or engineering application. These two trends are technically combined into mobile cloud computing environment taking beneficial points from each. The intention of this study is to design and implement a mobile cloud application for remotely sensed image fusion for the further practical geo-based mobile services. In this implementation, the system architecture consists of two parts: mobile web client and cloud application server. Mobile web client is for user interface regarding image fusion application processing and image visualization and for mobile web service of data listing and browsing. Cloud application server works on OpenStack, open source cloud platform. In this part, three server instances are generated as web server instance, tiling server instance, and fusion server instance. With metadata browsing of the processing data, image fusion by Bayesian approach is performed using functions within Orfeo Toolbox (OTB), open source remote sensing library. In addition, similarity of fused images with respect to input image set is estimated by histogram distance metrics. This result can be used as the reference criterion for user parameter choice on Bayesian image fusion. It is thought that the implementation strategy for mobile cloud application based on full open sources provides good points for a mobile service supporting specific remote sensing functions, besides image fusion schemes, by user demands to expand remote sensing application fields.

• BMB Reports
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• v.57 no.1
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• pp.30-39
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• 2024

Directed evolution (DE) of desired locus by targeted random mutagenesis (TRM) tools is a powerful approach for generating genetic variations with novel or improved functions, particularly in complex genomes. TRM-based DE involves developing a mutant library of targeted DNA sequences and screening the variants for the desired properties. However, DE methods have for a long time been confined to bacteria and yeasts. Lately, CRISPR/Cas and DNA deaminase-based tools that circumvent enduring barriers such as longer life cycle, small library sizes, and low mutation rates have been developed to facilitate DE in native genetic environments of multicellular organisms. Notably, deaminase-based base editing-TRM (BE-TRM) tools have greatly expanded the scope and efficiency of DE schemes by enabling base substitutions and randomization of targeted DNA sequences. BE-TRM tools provide a robust platform for the continuous molecular evolution of desired proteins, metabolic pathway engineering, creation of a mutant library of desired locus to evolve novel functions, and other applications, such as predicting mutants conferring antibiotic resistance. This review provides timely updates on the recent advances in BE-TRM tools for DE, their applications in biology, and future directions for further improvements.