• Journal of Welding and Joining
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• v.31 no.4
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• pp.73-79
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• 2013

Burr grinding, Tungsten Inert Gas (TIG) dressing, ultrasonic impact treatment, and peening are used to improve fatigue life in steel structures. These methods improve the fatigue life of weld joints by hardening the weld toe, by improving the bead shape, and by creating the compressive residual stress. In this study, a new post-weld treatment method improving the weld bead shape and metal structure at the welding zone using Friction Stir Processing (FSP), a welding process, is proposed to enhance fatigue life. For that, a pin-shaped tool and processing condition employing Friction Stir Processing (FSP) is established through experiments. Experimental results revealed that fatigue life is improved by around 50% compared to as-welded fatigue specimens by reducing the stress concentration at the weld toe and by generating a metal structure finer than that of flux-cored arc welding (FCAW).

• Proceedings of the Plant Resources Society of Korea Conference
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• 2018.04a
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• pp.38-38
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• 2018

The genus Carduus (Asteraceae), containing ca. 90 species, is mainly distributed in Eurasia and Africa. Carduus species are one of the most hazardous invasive species, which causes serious environmental threats and biodiversity damages in North America. Thus, the member of Carduus are targeted for classical biological control in this region. Here, we provide the complete cp genome of Carduus crispus using next-generation sequencing technology. The size of cp genomes of C. crispus is 152,342 bp. It shows a typical quadripartite structure, consisting of the large single copy (LSC; 83,254 bp), small single copy (SSC; 18,706 bp), separated by a pair of inverted repeats (IRs; 25,191 bp). It contains 115 unique genes of which 21 genes duplicated in the IR regions. The cpSSR regions of Carduus species were searched through the complete chloroplast genome sequence using a tandem repeat search tool in Geneious with the parameters set to ${\geq}7$ mononucleotide repeats, ${\geq}4$ di- and trinucleotide repeats, and ${\geq}3$ tetra-, penta-, and hexanucleotide repeats. A total of 22 repeat motifs were identified, which may be useful for molecular identification of Korean Carduus species (C. cripus), and providing a guideline for its conservation.

• Journal of Korean Academy of Nursing
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• v.32 no.5
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• pp.633-642
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• 2002

The purpose of this study was to evaluate the effect of a Yoga program on decreasing blood pressure in elderly patients with essential hypertension and to suggest a yoga program effective as a nursing intervention tool to reduced blood pressure with increasing life satisfaction. Method: The subjects of this study were 24 elderly's essential hypertension, who practiced yoga by three times a week for 8 weeks. In order to evaluate the effect of the yoga program, blood pressure, physiological parameters (Total cholesterol, HDL, LDL, triglycerides) and level of life satisfaction were measured before and after the training. Collected date were analyzed by SPSSWIN program. Result: 1) There were significant reduction in systolic and diastolic blood pressure. 2) There were significant reductions in total cholesterol, LDL, triglycerides but no significant increased in HDL. 3) Blood pressure changes were time specific : Both of systolic and diastolic blood pressures were significantly reduced after 2weeks. 4) There was a significant increase in life satisfaction. Conclusion: The results proved that a yoga program was an effective nursing intervention to reduce blood pressure and to increased life satisfaction for elderly patients with essential hypertension.

• Korean Journal of Health Education and Promotion
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• v.30 no.5
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• pp.163-175
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• 2013

Objectives: This study was performed to identify the relationship among sexual desire, other domains of sexual function and quality of life (QOL) and to describe the effect of sexual desire on sexual function and QOL in married women with hypoactive sexual desire disorder (HSDD). Methods: A total of 397 women with HSDD participated in this study. Data were collected through self-reported questionnaire which were constructed to include general characteristics items, Female Sexual Function Index (FSFI), and QOL tool. Data were analyzed using SPSS/WIN20 for descriptive statistics, t-test, one-way ANOVA, Duncan, partial correlation coefficients, and Hierarchial multiple regression. Results: There were significant correlations with sexual desire and other domains of sexual function. And also, sexual desire had a positive correlations with the psychological status and total QOL. The sexual desire was statistically significant predictors for sexual function and QOL. Conclusions: Health professionals should direct efforts toward developing sexual health-related counseling or education programs for women suffering from sexual dysfunction with the goal of helping them to achieve satisfying sex lives and improved quality of life.

• Genomics & Informatics
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• v.9 no.1
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• pp.39-43
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• 2011

MicroRNAs (miRNAs) are recently discovered small RNA molecules usually resulting in translational repression and gene silencing. Despite the fact that specific cloning of small RNA's is a method in practice, computational identification of miRNA's has been a major focus recent days, since is a rapid process following AB initio and sequence alignment methods. Here we developed new software called MiRPI that aims to identify the highly conserved miRNAs without any mismatches from given fasta formatted gene sequences by using non-repeated miRNA dataset of the user's interest. The new window embedded with the software is used to identify the targets for inputted mature miRNAs in the mRNA sequences. Also MiRPI is designed to measure the precursor miRNA statistics, majorly focusing the Adjusted Minimum Folding free Energy (AMFE) and Minimum Folding free Energy Index (MFEI), the most important parameters in miRNA confirmation. MiRPI is developed by PERL (Practical Extraction and Report Language) and Tk (Tool kit widgets) scripting languages. It is user friendly, portable offline software that works in all windows OS, sized to 3 MB.

• Proceedings of the Korean Society of Machine Tool Engineers Conference
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• 2005.05a
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• pp.185-190
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• 2005

The shot peening process is often used to improve fatigue properties of metal parts. Among them, It is the most use in an auto-component. In order to achieve optimum, repeatable and reliable fatigue enhancement from the shot peening process, the important shot peening parameters must be controlled. In this paper, the optimum peening intensity (Almen intensity) condition is investigated by experiment. The Spur Gear steel was used to investigate shot peening effects. The fatigue life at $\sigma_a=1,050$ and $\sigma_a=1,250MPa$ first gently increases, then drops gently as peening intensity increases compared with unpeened specimen. Experimental results show that the optimum peening intensity range is $0.391\~0.434mmA$..So the fatigue strength and fatigue life have been tremendously increased by optimum-peening treatment. However, the fatigue strength and fatigue life have been decreased by over peeing.

• Proceedings of the KSR Conference
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• 2005.11a
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• pp.1033-1038
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• 2005

As a global effort to conservate the environment, life cycle assessment(LCA) which considers the environmental impact through the life cycle of a product, from acquiring of resources to scrapping, has been actively applied. The LCA is a tool to calculate quantitatively the environmental impacts caused by products or services through their life cycles. The list of numerous data should be analyzed, stored and conducted in order to assess the environmental impacts. Therefore, it is necessary to develop a software for LCA, which can perform the interpretation as well as the environment impact assessment to execute the analysis of such a large number of data effectively. At this time, for the existing some kinds of general LCA softwares, the information about all of input and output should be fed directly and the conclusion is deduced by linking to the database from the public authorized organizations. That makes it possible to evaluate the environmental grades accurately, but it is too slow and difficult for general users to operate and applied it into an electric motor unit(EMU). Therefore, in this research, the basic model was designed, which is based on construction of database structure of the software and organization of architecture, to develop an advanced software for EMU according to user and purpose of it by benchmarking of domestic and international softwares. The result of this study would be applied to develop the LCA software in the future.

• Food Science and Biotechnology
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• v.18 no.3
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• pp.694-699
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• 2009

A multiplex polymerase chain reaction (PCR) method was developed for the detection of 4 events of genetically modified (GM) soybean. The event-specific primers were designed from 4 events of GM soybean (RRS, A2704-12, DP356043-5, and MON89788). The lectin was used as an endogenous reference gene of soybean in the PCR detection. The primer pair YjLec-4-F/R producing 100 bp amplicon was used to amplify the lectin gene and no amplified product was observed in any of the 9 different plants used as templates. This multiplex PCR method allowed for the detection of event-specific targets in a genomic DNA mixture of up to 1% GM soybean mixture containing RRS, A2704-12, DP356043-5, and MON89788. In this study, 20 soybean products obtained from commercial food markets were analyzed by the multiplex PCR. As a result, 6 samples contained RRS. These results indicate that this multiplex PCR method could be a useful tool for monitoring GM soybean.

• Molecules and Cells
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• v.27 no.2
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• pp.225-235
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• 2009

Antibody phage display provides a powerful and efficient tool for the discovery and development of monoclonal antibodies for therapeutic and other applications. Antibody clones from synthetic libraries with optimized design features have several distinct advantages that include high stability, high levels of expression, and ease of downstream optimization and engineering. In this study, a fully synthetic human scFv library with six diversified CDRs was constructed by polymerase chain reaction assembly of overlapping oligonucleotides. In order to maximize the functional diversity of the library, a ${\beta}$-lactamase selection strategy was employed in which the assembled scFv gene repertoire was fused to the 5'-end of the ${\beta}$-lactamase gene, and in-frame scFv clones were enriched by carbenicillin selection. A final library with an estimated total diversity of $7.6{\times}10^9$, greater than 70% functional diversity, and diversification of all six CDRs was obtained after insertion of fully randomized CDR-H3 sequences into this proofread repertoire. The performance of the library was validated using a number of target antigens, against which multiple unique scFv sequences with dissociation constants in the nanomolar range were isolated.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.6 no.5
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• pp.689-695
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• 2002

Film compositions are needed in semiconductor manufacturing for such diverse application as production tool qualifications and process development. Surface and interface information is generally provided with Auger electron spectroscopy(AES). In this paper, WSix films were analyzed for structural, electrical, and compositional properties of tungsten silicide thin films produced by low pressure chemical vapor deposition as a function of temperature, DCS post flow, shower head life time, and the silicon to tungsten ratios have been investigated. We find that Si/W composition ratio is increased in the surface and interface of WSix thin films by the DCS post flow process and increasing deposition temperature, respectively. The results obtained in this study are also applicable to process control of WSix deposition for memory device fabrication.