• 한국발생생물학회지:발생과생식
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• 제15권3호
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• pp.187-195
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• 2011

X chromosome inactivation (XCI) is a process that enables mammalian females to ensure the dosage compensation for X-linked genes. Investigating the mechanism of XCI might provide deeper understandings of chromosomal silencing, epigenetic regulation of gene expressions, and even the course of evolution. Studies on mammalian XCI conducted with mice have revealed many fundamental findings on XCI. However, difference of murine and human XCI necessitates the further investigation in human XCI. Recent success in reprogramming of differentiated cells into pluripotent stem cells showed the reversibility of XCI in vitro, X chromosome reactivation (XCR), which provides another tool to study the change in X chromosome status. This review summarizes the current knowledge of XCI during early embryonic development and describes recent achievements in studies of XCI in reprogramming process.

• 로봇학회논문지
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• 제15권2호
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• pp.131-138
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• 2020

This paper proposes a low-cost robotic surgery system composed of a general purpose robotic arm, an interface for daVinci surgical robot tools and a modular haptic controller utilizing smart actuators. The 7 degree of freedom (DOF) haptic controller is suspended in the air using the gravity compensation, and the 3D position and orientation of the controller endpoint is calculated from the joint readings and the forward kinematics of the haptic controller. Then the joint angles for a general purpose robotic arm is calculated using the analytic inverse kinematics so that that the tooltip reaches the target position through a small incision. Finally, the surgical tool wrist joints angles are calculated to make the tooltip correctly face the desired orientation. The suggested system is implemented and validated using the physical UR5e robotic arm.

• 한국공작기계학회:학술대회논문집
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• 한국공작기계학회 2003년도 추계학술대회
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• pp.351-355
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• 2003

Recently, the Rapid Prototyping System makes used of changing file format. The most problem is produced by this process. It is influenced by the precision of shape manufacturing. And It is most influenced by shrinkage rate within many elements influence the precision of 3D shape manufacturing. In result, the length strain in each axis cause at STL file transforming. It will compensate for utilizing the shrinkage rate.

• 한국공작기계학회논문집
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• 제10권4호
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• pp.70-75
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• 2001

In metal cutting, the machining accuracy is more affected by thermal errors than by geometric errors. This paper models of the thermal errors for error analysis and develops on-the-machine measurement system by which the volumetric error are measured and compensated. The thermal error is modeled by means of angularity errors of a column and thermal drift error of the spindel unit which are measured by the touch probe unit with a star type styluses, a designed spherical ball arti-fact, and five gap sensors. In order to analyze the thermal characteristics under several operating conditions, experiments performed with the touch probe unit and five gap sensors on the vertical and horizontal machining centers.

• 대한기계학회논문집A
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• 제28권7호
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• pp.986-991
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• 2004

For volumetric error measurement and calibration for machine tools, manufacturing machine or coordinate measuring machine (CMM), are studied using a Ball-bar artifact. A design of the Ball-bar is suggested manufactured by Invar, which is a low thermal expansion material, and precision steel balls. The uncertainty for the artifact method is discussed. A method of the Ball-bar artifact for obtaining 3-D position errors in CMM is proposed. The method of error vector measurement is shown using the Ball-bar artifact. Finally, the volumetric error is calculated from the error vectors and it can be used for Pitch error compensation in conventional NC machine and 3-D position Error map for calibration of NC machine tools.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 1997년도 춘계학술대회 논문집
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• pp.1044-1048
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• 1997

Wire-cut EDM is used in Die manufacturing as the part of non-traditional cutting process, But,the determination of it's cutting condition with high efficiency and precision is difficult due to the influence of cutting environment and cutting mechanism. In this study, we examine the cutting performance of the SKD11 and Brass in wire-cut EDM and make the neural network which have the configuration of 5-12-2 and back-propagation learning rule. Through the neural network, we can appraise the cutting performance before working and determine the optimal cutting condition. By introducing this method to the W-cut EDM, we can enhance the cutting efficiency.

• 한국공작기계학회논문집
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• 제17권1호
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• pp.106-112
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• 2008

In this paper, It does the profile measurement of the cam of diesel engine SOHC of the actual object. It uses the measurement of run-out method. This method is that the surface of the object is measured by the sensor when the object rotate, and calculated and displayed by the computer the signal which acquired by sensor. When we acquire the signals, we have two error because of motion and contacting between cam and probe. In this paper, we compensate the motion error while simply liner equation. And we have a solution that we change the figure of probe when we have a contacting error. We compared the data measuring on developed automatic cam profile measuring system with the data measured on CMM.

• 한국공작기계학회:학술대회논문집
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• 한국공작기계학회 2000년도 춘계학술대회논문집 - 한국공작기계학회
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• pp.379-384
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• 2000

The reactive and harmonic current components of dc loads can be compensated by the three-phase hybrid power filter (HPF) system. After compensation, the resulting current has sinusoidal and in-phase components with the source voltage. The HPF system is constructed by an active filter and passive filters. The passive filter reduce the 5th and 7th harmonic of the load current. The active filter compensates the remainder of the load current. Using the HPF system, a low cost harmonic compensator can be made. Performance of the HPF system is verified through simulation,

• 한국생산제조학회지
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• 제7권2호
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• pp.91-99
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• 1998

This paper presents a methodology for identifying the cutter runout geometry in end milling process. Cutter runout is common but undesirable phenomenon in multi-tooth machining because it introduces variable chip loading to insert which results in a accelerated tool wear. amplification of force variation and hence enlargement vibration amplitude From understanding of chip load change kinematics, the analytical cutting force convolution model was formulated as the angular domain convolution model was formulated as the angular domain convolution of three dynamic cutting force component functions. By virtue of the convolution integration property, the frequency domain expression of the local cutting forces and the chip width density of the cutter. Experimental study is presented to validate the analytical model. This study provides the in-process monitoring and compensation of dynamic cutter runout to improve machining tolerance and surface quality for industrial application.

• Design & Manufacturing
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• 제2권1호
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• pp.11-14
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• 2008

we can save a development cost and time as computer was used in tool and die design of car fields in die manufacture process. Dimension accuracy errors such as springback, springgo, overcrown and twist were reduced product accuracy and caused trouble to assembly each parts of car. In this paper, CADCEUS was used to modify and optimize results of deflection for a tail gate panel of car parts in order to reduce dimension accuracy errors by springback in sheet metal forming. As CADCEUS was used to apply for a tail gate panel, the time for quality to improve was reduced to 30%.