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Development of Antimicrobial Dye for Natural Dyeing using Natural Substances (천연물을 이용한 항균성 염료의 개발)

  • Yu, Young-Eun;Park, Eun-Young;Jung, Dae-Hwa;Byun, Sung-Hui;Kim, Sang-Chan;Park, Sung-Min
    • Microbiology and Biotechnology Letters
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    • v.38 no.1
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    • pp.32-39
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    • 2010
  • This study was carried out to investigate the usefulness of the natural antimicrobial substances for natural dyeing. Antimicrobial activity of natural substances, extracted by water, ethanol, methanol and ethyl acetate, were shown over 20 mm by Rheum palmatum, Caesalpinia sappan, Prunus mume, Schizandra chinensis, Rhus javanica, and Coptis japonica. Especially, water and methanol extract of C. japonica were shown strong antimicrobial activity against all investigated strains. Minimum inhibition concentration of C. japonica water extract was investigated 110 mg/mL for Staphylococcus aureus ATCC 6538. Investigated natural substances were not only shown strong antimicrobial activity for natural dyeing but also might be used other industries.

Immunoenhancing Effect of Conjugated Linoleic Acids on Phagocytic Activity of Porcine Peripheral Blood Phagocytes (돼지 말초혈액 탐식세포의 탐식활성에 있어서 CLA의 면역증강효과)

  • Kang Ji-houn;Kim Ju-hyang;Chung Chung-soo;Lee Chul-young;Yang Mhan-pyo
    • Journal of Veterinary Clinics
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    • v.21 no.4
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    • pp.336-342
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    • 2004
  • The immunoenhancing effect of CLA isomers (CLA mixture, 10t-12c CLA, 9c-11c CLA, 9c-11c CLA, and 9t-11t CLA) on phagocytic activity of porcine peripheral blood leukocytes was examined. The phagocytic activities of peripheral blood mononuclear cells (PBMC) and polymorphonuclear cells (PMN) were analyzed by a flow cytometry system. The direct treatments of CLA isomers have no effect on phagocytosis of PMN as well as PBMC composed of approximately 10% monocytes and 90% lymphocytes. However, the phagocytic activities of PMN and monocyterich fraction from PBMC were remarkably enhanced by culture supernatant from PBMC treated with CLA mixture, 10t-12c CLA and 9c-11t CLA but not 9c-11c CLA and 9t-11t CLA. The phagocytic activity of PBMC was not enhanced by culture supernatant from PBMC treated with all CLA isomers. These results indicated that CLA isomers such as CLA mixture, l0t -12c CLA and 9c-11t CLA have an enhancing effect on phagocytosis of PMN and monocytes, which may be mediated through active humoral substances produced by CLA-stimulated PBMC. This study suggested that CLA stimulates PBMC to elaborate soluble factor(s), which may be an important mechanism for the enhancement of phagocytosis in non-specific immunity.

A Study on the Estimation of Energy Expenditure and falls measurement system for the elderly (고령자를 위한 에너지 소비 추정 및 낙상 측정 시스템에 관한 연구)

  • Lim, Chae-Young;Jeon, Ki-Man;Ko, Kwang-Cheol;Koh, Kwang-Nak;Kim, Kyung-Ho
    • Journal of the Korea Society of Computer and Information
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    • v.17 no.4
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    • pp.1-9
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    • 2012
  • As we are turnning into the aged society, accidents by falling down are increasing in the aged people's group. In this paper, we design the system with the 3-Axis acceleration sensor which is composed by a single chip. The body activity signal is measured with the signal detector and RF communicator in this proposed system and the and falling by the entering signal pattern analysis with 3-Axis acceleration sensor. For the RF communication, we are using nRF24L01p and 8bits ATmega uC for the processor. The error of energy expenditure estimation between motor driven treadmill and proposed a body activity module was 7.8% respectively. Human activities and falling is monitored according to analyze and judge the critical value of the Signal Vector. as falled down if they don't turn off the alarm after specific period and the aged person's after falling down activities are their position and more.

The Distribution of Heavy Metals in the Surface Waters and Sediments of Gaduk Channel in Jinhae Bay, Korea (진해만의 가덕수도 표층수와 표층 퇴적물 중의 중금속 분포)

  • Kim, Kyung-Tae;Kim, Eun-Soo;Cho, Sung-Rok;Kahng, Sung-Hyun;Kim, Jong-Kun;Park, Jun-Kun
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.14 no.2
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    • pp.95-103
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    • 2008
  • Heavy metals in the surface seawaters and sediments were measured in Gaduk channel of jinhae Bay. The high concentrations of heavy metals in the seawaters were found at the stations near the islands. In the seawaters, the mean concentrations of dissolved heavy metals except for Pb were not higher than previous data in this bay. Higher heavy metal contents in the surface sediments were observed at the stations adjacent to the Geojedo or Gadukdo of the Gaduk channel. The contents of Co,Ni,Zn,Cu,As and Cd in the surface sediments showed relatively high correlation coefficients with IL and COD. The order of enrichment factors(EFs) of heavy metals in the sediments on the basis of average shale values was As>Cd>Pb>Zn>Co>Cu>Hg>Ni, and the EFs of As,Cd,Pb and Zn at whole stations were higher than 1. EFs of Ni and Zn on the basis of natural background concentration in Korean coastal sediments were lower than EFs by average shale.

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Synthesis and Characterization of Poly(L-lactide)(L-PLA), Poly(D-lactide)(D-PLA) and Stereocomplex-poly(lactide)(PLA) (L-폴리락타이드, D-폴리락타이드의 활성과 입체복합체 폴리락타이드의 제조 및 특성연구)

  • Kim, Ji-Hyun;JeGal, Jong-Geon;Song, Bong-Keun;Shin, Chae-Ho
    • Polymer(Korea)
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    • v.35 no.1
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    • pp.52-59
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    • 2011
  • L-PLA or D-PLA was synthesized in bulk at $140^{\circ}C$ by ring opening polymerization(ROP) of L-lactide or D-lactide as a monomer using tin(II) octoate and lauryl alcohol as a catalyst and an initiator with changing the amounts of catalyst(0.25~1.0 wt%) and initiator(0.l~0.5 wt%). And stereocomplex-PLA was prepared by L-PLA/D-PLA having a wide range of molecular weight(30000~90000 g/mol) and L-PLA/D-PLA blends having different mixing ratio ($X_D$). The melting temperature. thermal degradation temperature and thermal stability of stereocomplex-PLA were higher than those of homopolymers(L-PLA, D-PLA). We supposed that these improvements arose from a strong interaction between L-PLA and D-PLA. The improved mechanical properties and changes in morphology of LPLA/D-PLA blends were compared to those of homopolymers(L-PLA, D-PLA).

Therapeutic Effects of Jeulminmilmae-tang on an Animal Model with Allergic Rhinitis (알레르기성 비염 동물 모델에서 截敏蜜梅湯이 비염치료에 미치는 영향)

  • Hwang, Hack-soo;Choi, In-hwa
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.16 no.3
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    • pp.116-128
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    • 2003
  • Objectives : The incidence of allergic rhinitis has increased but treatment in most cases has only dealt with the symptoms. Medicine has been developed that shows fewer side effects. However, some side effects and the psychological stress over taking medicine has remained. There have been no studies so far performed on the effect of this Jeulminmilmae-tang's use, only. The purpose of this study was find out the therapeutic effects of its exclusive use on an Animal Model with Allergic Rhinitis. Methods : Thirty Sprague-Dawley rats were divided into three group : normal group, control group and sample group. To induce the allergic rhinitis in control group and sample group, rats were sensitized intraperitoneally with 0.1$\%$ ovalumin solution 3 times at intervals of 1 week. Then intranasal sensitization was performed by diffusing 0.1$\%$ ovalumin solution 3 times at intervals of 2 days. After that time, rats in the sample group were oral administration treated by Jeulminmilmae-tang for 28 days. Compared with the sample group, rats in the control group were oral administration treated by normal saline for 28 days. We observed changes in nasal mucosa and submucosa; also changes in the segment of neutrophil, eosinophil, Iympocyte and monocyte in blood. We used the statistical methods of student t-test(p 〈0.05). And we observed the changes of AST, ALT of three groups and used anova test statistically. Results : The segment of eosinophil was significantly decreased in treated group when compared with the control group(p 〈0.05). The segment of neutrophil. in blood were decreased in the treated group when compared with the control group but. that was not significant statistically(p 〈0.05). There were some regrowth of the cilium in the treated group. Histologic changes showed edema congestion and expantion of grandular cells in nasal submucosa and hypertrophy of epithelium ill nasal mucosa were decreased in treated group when compared with control group. Effects of Jeulminmilmae-tang on the liver function were also studies in rats. Treatment of Jeulminmilmae-tang did not affected on AST and ALT. Conclusions : The results may suggest that oral administration treatment using Jeulminmilmae-tang decreases the inflammatory response on an Animal Model with Allergic Rhinitis.

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Effects of Adenophorae Radix(AR) on Atopic Dermatitis(AD) Induced by DNCB in Mice (사삼이 DNCB로 유발된 생쥐의 아토피 피부염에 미치는 영향)

  • Lim, Kyeong-Min;Ko, Hong-Je;Choi, Jung-Hwa;Park, Soo-Yeon;Kim, Jong-Han;Jung, Min?Yeong
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.30 no.3
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    • pp.31-45
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    • 2017
  • Objectives : Adenophorae Radix(AR) is the dried root of Adenphora triphylla var. japonica HARA. AR has the efficacy of clarifying lung, emitting pus, expelling wind, stopping pruitus and so on. Recently, various studies are being done about anti-oxidative, immunomodulatory and anti-inflammatory effects of AR. So, we expected AR has an availability that can improve symptoms of atopic dermatitis(AD). Methods : In this study, we measured body weight, weight of ear, thickness of ear skin and dorsum skin, symptom score, reproduction rate of splenocytes in vivo and in vitro of mouse with AD induced by DNCB. We experimented with five groups of 9 mice, such as normal group, control group, AR spread(ARS) group, AR feeding(ARF) group, AR spread&feeding(ARSF) group. Results : Control group of body weight significantly reduced and APSF group significantly increased in the first and second week. In weight of ear and thickness of ear skin and dorsum skin, control group significantly increased and ARSF group significantly decreased. In macrophotography viewpoint of dorsal skin, ARS group, ARF group and ARSF group decreased severe pigmented skin lesion, erythema and desquamation as compared with control group. Especially ARSF group showed significant drop. ARS group, ARF group and ARSF group compared to control group were improved in histopathology observation. In vitro and in vivo, treatment group of AR increased proliferation rate of splenocytes, specially in vitro significantly. Conclusions : This experiment indicates Adenophorae Radix extracts is effective on AD induced by DNCB in mice.

The signal processing of moire fringes obtained by the superposition of a fixed self-imaging elongated circular(EC) grating and a moved EC grating for the precise measurement of linear transverse displacements (정밀한 선형 횡변위 측정용 elongated circular 격자의 자체결상을 이용한 무아레 무늬의 신호처리법)

  • Lee Sang Il;Baek Seung Sun;Jo Jae Heung
    • Korean Journal of Optics and Photonics
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    • v.15 no.5
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    • pp.435-442
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    • 2004
  • We obtained precise linear transverse displacements from the results of signal processing on moire fringes measured by the superposition of a fixed self-imaging elongated circular(EC) grating and a moved EC grating. The linear displacement less than one pitch of the moving EC grating was calculated from the position of a bright moire fringe generated on the linear grating part of the EC gratings. The moire signals were high-frequency-filtered, smoothed, curve-fitted, and first-differentiated moire signals in sequence. Also the linear displacement created by movement by the unit of integer times of a pitch was readily measured by the count of the even number of zero-crossing points corresponding to bright moire fringes obtained by the above same processing without curve fitting. Then we can measure linear transverse displacements with the accuracy of better than 3 %, which are more accurate values than those by the traditional visual method within the displacement of 80 ${\mu}{\textrm}{m}$.

A Study on how to improve Survey of Fire Safety Management of manufacturing plants (The Medium and Small-sized Manufacturing industry) (제조 사업장의 소방안전관리 실태조사 및 개선방안에 대한 연구 (중소규모 제조사업장 중심으로))

  • Choe, Yeong-Gi;Kim, Byeong-Seok
    • Proceedings of the Safety Management and Science Conference
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    • 2013.11a
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    • pp.483-497
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    • 2013
  • 현대사회가 발전 할수록 대량산업화와 도시화가 심화되어 건축물의 초고층화 및 대형화가 증가하고 있으며, 안전적인 건축물 보다는 건물 및 제조사업장의 시각적인 디자인에 치우쳐 화재하중이 높은 건축자재의 내 외장재 및 고급스러운 장식물을 사용함으로써 그 위험뿐 만 아니라 화재발생시 대규모 인명 및 재산상의 피해를 가져오게 된다. 그리고 제조사업장화재는 화재로 인한 직접적인 손실 즉 물적 손실은 물론 생산중단으로 인한 간접적인 손실은 실로 측정하기가 어렵다. 지금까지 발생한 제조사업장화재의 발화요인별 분석은 부주의, 전기적, 미상 순으로 인한 화재가 가장 많고 발화열원은 작동기기, 담뱃불(라이터), 마찰 전도 복사등이 주요 원인이 되고 있고 대형화제 취약시설로는 공장 및 창고로 나타나고 있다. 소방방재청의 통계자료를 살펴보면 2012년 화재 발생현황 중 발화요인에 대한 화재별 장소 건수를 검토 한 결과 비주거의 화재발생 16,009건 중 5,758건으로 (36%)부주의이고, 주거에도 화재발생 10,715건 중 5,560건으로 51.9%의 부주의로 가장 높은 것으로 나타났다. 그러므로 제조사업장의 사소한 부주의로 발생하는 화재를 예방하기 위해서는 소방안전관리자의 처우개선과 기업활동규제완화의 겸직 허용을 재검토 하여야 하며, 소방안전관라자의 실무능력 강화를 위한 소방안전관리 실무교육과정을 이론적 교육 보다는 현장 실습위주로 할 필요가 있다. 이를 위해서는 소방안전관리자에 대한 법정 실무교육 횟수를 확대하여 현행 2년에 1회 에서 1년에 1회로 하고, 실무교육에 있어서도 우수송방안전관리 업체를 선정하여 화재예방에 대한 구체적인 업무를 활성화 하고, 문제 발생요소들을 분석하여 실습을 통한 소방안전관리자의 실무교육을 실시해야 할 것이다. 이러한 전문 소방안전관리자로 소방대상물의 소방교육 및 훈련을 성실히 수행 해야 할 것 이다. 한순간의 부주의로 인하여 화재가 발생하면 돌이킬 수 없는 수백명의 생명을 앗아가고, 수백억원대의 재산피해를 줄이기 위해서는 소방안전관리자의 역량을 넓히고 화재예방 업무를 최우선적으로 수행해야 할 것이다. 화재예방을 위해 소방안전관리자의 업무개선 및 전문교육을 활성화 하여 업무능력을 향상 시켜 화재발생시 초기진압에 신속하고 정확하게 대처해야 한다는 것이 전문적인 화재예방 대책 일 것이다.

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An Experimental Study on the Heat Transfer Characteristics during Outward Melting Process of Ice in a Vertical Cylinder(comparison of thermal performance on the flow direction of working fluid) (수직원통형 빙축열조내 얼음의 외향용융과정시 전열특성에 관한 실험적 연구(작동 유체의 유입 방향에 따른 비교))

  • Kim, D.H.;Kim, D.C.;Kim, I.K.;Kim, Y.K.;Yim, C.S.
    • Solar Energy
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    • v.16 no.2
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    • pp.113-122
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    • 1996
  • This study presents experimental results of heat transfer characteristics of P.C.M. during outward melting process in a vertical cylinder. The experiment was carried out in six conditions, i. e., three different inlet temperature($7^{\circ}C,\;4^{\circ}C\;and\;1^{\circ}C$) and two directions of working fluid(upward and downward). Melting P.C.M. produced a bell-shaped phase change interface. When the inlet temperature was $7^{\circ}C$, the lower region remained at $4^{\circ}C$ until the temperature of upper region reached $4^{\circ}C$. This was due to the state of maximum density of the lower region. When the direction of the working fluid in the case of $7^{\circ}C$, inlet temperature, was upward, the rate of melting and the total melting energy were higher than when it's direction was downward. But the rate of melting and the total melting energy appeared higher value as it's direction was downward when the inlet temperature is $4^{\circ}C$ and $1^{\circ}C$.

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