• Nuclear Engineering and Technology
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• v.54 no.1
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• pp.262-268
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• 2022

This paper introduces a novel concept of the pulsed neutron facility (PNF) for maximizing the production of the thermal neutrons and its application to medical use based on prompt gamma neutron activation analysis (PGNAA) using Monte Carlo simulations. The PNF consists of a compact D-T neutron generator, a graphite pile, and a detection system using Cadmium telluride (CdTe) detector arrays. The configuration of fuel pins in the graphite monolith and the design and materials for the moderating layer were studied to optimize the thermal neutron yields. Biological samples - normal and cancerous breast tissues - including chlorine, a trace element, were used to investigate the sensitivity of the characteristic γ-rays by neutron-trace material interactions and the detector responses of multiple particles. Around 90 % of neutrons emitted from a deuterium-tritium (D-T) neutron generator thermalized as they passed through the graphite stockpile. The thermal neutrons captured the chlorines in the samples, then the characteristic γ-rays with specific energy levels of 6.12, 7.80 and 8.58 MeV were emitted. Since the concentration of chlorine in the cancerous tissue is twice that in the normal tissue, the count ratio of the characteristic g-rays of the cancerous tissue over the normal tissue is approximately 2.

• Proceedings of the Korean Society for Agricultural Machinery Conference
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• 2000.11c
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• pp.715-721
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• 2000

In this research, rule and neuro net based boundary extraction algorithm was developed. Extracting boundary of the interest, lean tissue, is essential for the quality evaluation of the beef based on color machine vision. Major quality features of the beef are size, marveling state of the lean tissue, color of the fat, and thickness of back fat. To evaluate the beef quality, extracting of loin parts from the sectional image of beef rib is crucial and the first step. Since its boundary is not clear and very difficult to trace, neural network model was developed to isolate loin parts from the entire image input. At the stage of training network, normalized color image data was used. Model reference of boundary was determined by binary feature extraction algorithm using R(red) channel. And 100 sub-images(selected from maximum extended boundary rectangle 11${\times}$11 masks) were used as training data set. Each mask has information on the curvature of boundary. The basic rule in boundary extraction is the adaptation of the known curvature of the boundary. The structured model reference and neural net based boundary extraction algorithm was developed and implemented to the beef image and results were analyzed.

• Journal of Korea Technical Association of The Pulp and Paper Industry
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• v.36 no.4 s.107
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• pp.77-82
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• 2004

Expression-deliquoring tests using three types of paper sludges (tissue, newsprint, and paperboard) as deliquoring agent were carried out in order to investigate the effects of sludge dosage and pressure on the expression-deliquoring of slurry. The addition of deli­quoring agent causes expression-deliquoring of slurry to be faster than would be the case without the deliquoring agent. In case of the tissue sludge, the highest compression rate was achieved when $5\%$ of deliquoring agent was added, while in cases of the news­print and the paperboard sludge, $7\%$. Compression rate was increased as pressure increases. Porosity was decreased as pressure increases. The lowest porosity was observed when $5\%$ of tissue sludge was added. When compared the weight of cake where deliquoring agent was not added and the weight of cake that was fastest expression-deliquoring, there was about $17.5\%$ of the weight reduction

• Journal of Biomedical Engineering Research
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• v.28 no.3
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• pp.392-396
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• 2007

In this paper, we develop a new system to visualize the blood flow map in skin tissue, using the technique of Laser Speckle Flowgraphy (LSFG). The measuring unit consists of the laser diode, imaging system, line sensor, scanning mirror, and one-board microcomputer. The speckle signal is analyzed and sent to a PC, where the blood flow in a tissue area of $14mm{\times}26 mm$ is evaluated and displayed in a 2-D color map. It is demonstrated that the new LSFG instrument is useful to evaluate the degree of allergic reaction in patch test.

• Journal of Biomedical Engineering Research
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• v.4 no.1
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• pp.29-36
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• 1983

In this paper, center frequency down slift of ultrasonic echo signals which for the measurements of frequency dependent attenuation in the biological tissue are estimated. Center frequency down shift of echo-signals are estimated after signal spectrum analysis of whole echo-signals. In case of signal spectrums are simple, estimation of down shift frequency is very simple and in case of complicate spectrum, estimation of down shift frequency is depend on spectral shape. In case of unable to estimate, frequency dependence of medium is nonlinear(n) 1), in which upper shift of spectrums are presented. In case of unable to estimate, spectrum analysis are performed at local position. At consquence, we know that spectral dispersions are caused complicately by biological tissue layer.

• Proceedings of the PSK Conference
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• 2003.04a
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• pp.302.2-303
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• 2003

For polymeric material for tissue engineering. chitosan was selected with benefit of high tissue compatibility attributed and wound healing through its activation of growth factors. And nonwoven chitosan fibrous matrix has well interconnected porosity. But chitosan itself has some of limitations in including rapid bone regeneration at initial states incorpor-ated of bioactive materials such as growth factors and ECM molecules. (omitted)

• Transactions of the Korean Society for Noise and Vibration Engineering
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• v.19 no.9
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• pp.928-934
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• 2009

Underwater impulsive sound such as underwater blasting noise, piling noise and stone breaking hammer affects marine animal hearing response and organs. This study describes the characteristics of various impulsive noise from waterfront construction site and their effect on fish. Time constant, peak pressure, energy and SEL(sound exposure level) of four different underwater impulsive sounds are quantified. Auditory and non-auditory tissue damage ranges are derived by comparing their quantities to the exposure criteria for fish. Damage ranges of auditory tissue and non-auditory tissue of underwater boring blast of 150 kg of charge, are about 100 m and 300 m, respectively. Other three impulsive sounds also gives damage effects but less than that of underwater boring blast.

• Journal of the Optical Society of Korea
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• v.13 no.3
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• pp.321-329
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• 2009

Following their applications in cardiology, ophthalmology and dentistry among others, the advent of lasers in dermatology and urology had become the success story of the past decade. Laser-assisted treatments in dermatology and urology are mainly based on the laser-induced tissue injury/coagulation and/or ablation, depending upon the desirable clinical endpoint. In this review, we discussed the underlying mechanisms of the laser induced tissue ablation. In any medical laser application, the controlled thermal injury and coagulation, and the extent of ablation, if required, are critical. The laser thermal mechanism of injury is intricately related to the selective absorption of light and its exposure duration, similarly to the laser induced ablation. The laser ablation mechanisms were categorized into four different categories (the photo-thermally induced ablation, the photo-mechanically induced ablation, the plasma induced ablation and the photoablation) and their fundamentals are herein described. The brief history of laser treatment modality in dermatology and urology are summarized.

• The Journal of the Acoustical Society of Korea
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• v.29 no.1E
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• pp.1-10
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• 2010

The difference in echogenicity between cancerous and normal tissues is not quite distinguishable in ultrasound B-mode imaging. However, tumor or cancer in breast or prostate tends to be stiffer than the surrounding normal tissue. Thus, imaging the stiffness contrast between the two different tissue types is helpful for quantitative diagnosis, and such a method of imaging the elasticity of human tissue is collectively referred to as ultrasound elasticity imaging. Recently, elasticity imaging has established itself as an effective diagnostic modality in addition to ultrasound B-mode imaging. The purpose of this paper is to present various elasticity imaging methods that have been reported up to now and to describe their principles of operation and characteristics.

• Current Optics and Photonics
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• v.1 no.5
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• pp.551-555
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• 2017

Tissue optics is a well-established and extensively studied area. In the last decades, Monte Carlo simulation (MCS) has been one of the standard tools for simulation of light propagation in turbid media. The utilization of parallel processing exhibits dramatic increase in the speed of MCS's of photon migration. Some calculations based on MCS can be completed within a few seconds. Since the MCS's have the potential to become a real time calculation method, a dynamic accuracy estimation, which is also known as history by history statistical estimators, is required in the simulation code to automatically terminate the MCS as the results' accuracy achieves a high enough level. In this work, spatial and time-domain GPU-based MCS, adopting the dynamic accuracy estimation, are performed to calculate the light dose/reflectance in homogeneous and heterogeneous tissue media. This dynamic accuracy estimation can effectively derive the statistical error of optical dose/reflectance during the parallel Monte Carlo process.