• Journal of the Korean Society of Radiology
• /
• v.1 no.2
• /
• pp.31-35
• /
• 2007

Energy calibration is important to identify accurate neutron capture resonance energy in the neutron TOF (Time-of-Flight) experiment. In present study, the accurate neutron capture resonance energies of natural Sm were measured by using a 46-MeV electron linear accelerator (linac) at the Research Reactor Institute, Kyoto University(KURRI). The BGO spectrometer were adopted for measurement the prompt capture gamma-ray of the sample. To obtain energy calibration curve, resonance energy of a gold sample used as standard resonance energy Mughabghab's data (From neutron resonance parameters data). Previous data (by Mughabghab) of natural Sm sample have been compared with the present result.

• Proceedings of the Microbiological Society of Korea Conference
• /
• 2003.05a
• /
• pp.77-79
• /
• 2003

Current therapeutic strategies far anthrax have had no significant impact on anthrax mortality over the last several decades. This study used a matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) discovery platform to generate protein expression profiles in search of overexpressed proteins in murine macrophage cells (RAW264.7) which infected with Bacillus anthracis spores as potentially novel molecular targets. Two differentially expressed proteins were identified in infected murine macrophage cells as Syndapin and CDC46, respectively. Syndapins are potential links between the cortical actin cytoskeleton and endocytosis. Other two proteins were identified from murine macrophage cells infected with avirulent spores as ITBG-2 (CD18) and HSPA5, respectively. These data demonstrate the feasibility of using a MALDI-TOF platform to generate protein expression profiles and identify potential molecular targets for anthrax therapeutics.

• Journal of the Korea Institute of Military Science and Technology
• /
• v.20 no.6
• /
• pp.733-742
• /
• 2017

LADARs are used for important sensors in various applications, for example, terrain information sensors in self driving cars, safety sensors for factory automation, and 3D map constructions. This study develop important component technologies to improve the performance of a LADAR system under development in Korea. The component technologies include diode temperature regulation, reducing distance error in outdoor environment, and signal processing technique for better detection of distant objects. This paper explains the suggested component technologies and experimental results of the developed LADAR system. Also, the developed system is operated and tested an a single axis driving platform to acquire 3D information from 2D LADAR.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
• /
• 2005.07a
• /
• pp.578-580
• /
• 2005

Energy distribution function for electrons in SF6-Ar mixtures gas used by MCS-BEq algorithm has been analysed over the E/N range 30~300[Td] by a two term Boltzmann equation and by a Monte Carlo Simulation using a set of electron cross sections determined by other authors, experimentally the electron swarm parameters for 0.2[%] and 0.5[%] $SF_6$-Ar mixtures were measured by TOF method, The results show that the deduced electron drift velocities, the electron ionization or attachment coefficients, longitudinal and transverse diffusion coefficients and mean energy agree reasonably well with theoretical for a rang of E/N values. The results obtained from Boltzmann equation method and Monte Carlo simulation have been compared with present and previously obtained data and respective set of electron collision cross sections of the molecules.

• Mass Spectrometry Letters
• /
• v.4 no.2
• /
• pp.38-40
• /
• 2013

Glycans released from ovalbumin by PNGase F were analyzed by matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry using three different dihydroxybenzoic acid (DHB) matrix systems: 2,5-DHB, 2,6-DHB, and a 2,5-DHB/2,6-DHB binary matrix. Relative to the results obtained with the single-component matrices (2,5-DHB or 2,6-DHB), the 2,5-DHB/2,6-DHB binary matrix boasted lower background noise and higher sensitivity. A total of 16 glycan peaks were observed using the 2,5-DHB/2,6-DHB binary matrix, while only 10 and 9 glycan peaks were observed using the 2,5-DHB and 2,6-DHB matrices, respectively.

• Proceedings of the KSMRM Conference
• /
• 2003.10a
• /
• pp.98-98
• /
• 2003

We will present various MR findings of hyperacute ischemic stroke with our own experiences in the management of the patients according to the findings. 대상 및 방법： A total of 441 patients were underwent 'acute stroke MR' imaging protocol between Mar. 2001 and Jun. 2003. The protocol included initial T2-weighted image (WI), diffusion WI (DWI, b=2000), time-of-flight (TOF) MR angiography (MRA), and pefusion WI(PWI), and follow-up T2WI, DWI, TOF MRA, and neck vessel contrast-enhanced MRA obtained three to five days after the insult. Among them, we retrospectively reviewed the MR findings and clinical courses of 193 patients with anterior circulation territorial infarction. Those ICA and MCA lesions were divided into six and five groups respectively according to the level and mechanism of the occlusion. PWI findings can be another factor in the management planning.

• Biomedical Science Letters
• /
• v.23 no.4
• /
• pp.395-401
• /
• 2017

Various preclinical and clinical trials have been conducted the efficacy of celastrol. In data presented in the current manuscript is the first trial to inhibit Helicobacter pylori with celastrol. In this study, the quantitative change of various H. pylori proteins including CagA and VacA by the anti-bacterial effect of celastrol was determined. The anti-H. pylori effects of celastrol was investigated by performing 2-dimensional electrophoresis and additional supporting experiments. After 2-dimensional electrophoresis analysis, spot intensities were analyzed and then each spot was identified using matrix assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF-MS) or peptide sequencing using Finnigan LCQ ion trap mass spectrometer (LC-MS/MS). The results show that celastrol has multiple effects on protein expression in H. pylori.

• Proceedings of the Korean Society of Broadcast Engineers Conference
• /
• 2011.07a
• /
• pp.373-375
• /
• 2011

최근 들어, Time-of-Flight (TOF) 방식의 깊이 센서가 컴퓨터 비전이나 영상처리분야 등의 연구에서 다양하게 활용되고 있다. TOF 방식의 깊이 센서는 실시간으로 정확한 깊이 정보를 획득할 수 있는 장점이 있는 반면, 해상도가 낮고 센서의 광학적 특성으로 인해 노이즈가 발생한다는 단점이 있다. 본 논문에서는 이러한 깊이 센서의 단점을 극복하고 고품질의 다시점 영상 합성을 위해 기존 깊이 센서에 여러 대의 Charge-coupled Device (CCD) 카메라를 결합하여 시점 간 일관성 있는 고해상도의 깊이 영상을 획득하는 기술을 제안한다. 한정되어 있는 시점의 영상을 이용하여 다시점 영상을 합성할 때, 각 시점에 해당하는 깊이 영상의 정확도에 따라 합성되는 영상의 품질이 결정된다. 따라서 보유 시점에 해당하는 깊이 영상 간의 일관성이 유지되고 객체의 경계가 정확히 보존되어야만 생성되는 임의 시점 영상의 품질이 보장될 수 있다. 이에, 본 논문에서는 Joint Bilateral Upsampling (JBU)을 기반으로 시점 간 일관성을 고려한 깊이 영상의 해상도 개선 기술을 제안하고 이를 통해 다시점 영상 합성 결과의 품질을 향상시킨다.

• Biotechnology and Bioprocess Engineering:BBE
• /
• v.11 no.3
• /
• pp.187-198
• /
• 2006

The aromatic hydrocarbons (AHs), which include benzene, polycyclic aromatic hydrocarbons, and dioxin, are important chemical and environmental contaminants in industry that usually cause various diseases. Over the years, numerous studies have described and evaluated the adverse health effects induced by AHs. Currently, "Omics" technologies, transcriptomics and proteomics, have been applied in AH toxicity studies. Proteomics has been used to identify molecular mechanisms and biomarkers associated with global chemical toxicity. It could enhance our ability to characterize chemical-induced toxicities and to identify noninvasive biomarkers. The proteomic approach (e.g. 2-dimensional electrophoresis [2-DE]), can be used to observe changes in protein expression during chemical exposure with high sensitivity and specificity. Matrix-assisted laser desorption/ionization-time of flight mass spectrometry (MALDI-TOF MS) and electrospray ionization-quadrupole (ESI-Q)-TOF MS/MS are recognized as the most important protein identification tools. This review describes proteomic technologies and their application in the proteomic analysis of AH toxicity.

• Proceedings of the Korean Society of Broadcast Engineers Conference
• /
• 2012.07a
• /
• pp.26-28
• /
• 2012

본 논문에서는 깊이 영상의 해상도를 향상시키는 기법을 제안한다. 최근 TOF(time-of-flight) 방식의 깊이 센서가 깊이 영상 획득에 많이 사용되고 있다. 그러나 TOF 깊이 센서가 제공하는 깊이 영상은 대부분 저해상도이기 때문에 고해상도의 콘텐츠 제작을 위해서는 깊이 영상의 해상도를 향상시켜주는 것이 필수적이다. 본 논문에서는 깊이 영상의 해상도를 높이기 위하여 적응적 가중치 보간법을 적용한 후, Bilateral 필터링을 수행하여 품질을 높인다. 일반적으로 영상의 해상도를 높일 때 보간법을 많이 사용하는데, 본 논문에서는 이러한 보간법들을 사용하여 깊이 영상의 해상도를 높였을 때보다 제안하는 기법의 성능이 우수함을 실험을 통해 확인하였다.