• Title/Summary/Keyword: Time-of-day

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Impact of Time Interval between Index Event and Stenting on Periprocedural Risk in Patients with Symptomatic Carotid Stenosis

  • Han, Wonsuck;Hwang, Gyojun;Oh, Sung Han;Lee, Jong Joo;Kim, Mi Kyung;Chung, Bong Sub;Rhim, Jong Kook;Sheen, Seung Hun;Kim, Taehyung
    • Journal of Korean Neurosurgical Society
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    • 제63권5호
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    • pp.598-606
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    • 2020
  • Objective : The purpose of this study was to evaluate the impact of time interval between index event and stenting on the periprocedural risk of stenting for symptomatic carotid stenosis and to determine the optimal timing of stenting. Methods : This retrospective study included 491 (322 symptomatic [65.6%] and 169 asymptomatic [34.4%]) patients undergoing carotid stenting. The symptomatic patients were categorized into Day 0-3, 4-7, 8-10, 11-14, 15-21, and >21 groups according to the time interval between index event and stenting. Periprocedural (≤30 days) risk for clinical (any neurological deterioration) and radiological (new infarction on postprocedural diffusion-weighted imaging) events of stenting in each time interval versus asymptomatic stenosis was calculated with logistic regression analysis adjusted for confounders, and provided as odds ratio (OR) and 95% confidence interval (CI). Results : Overall clinical event rate (4.3%) of stenting for symptomatic carotid stenosis was higher than that for asymptomatic stenosis (1.2%; OR, 3.979 [95% CI, 1.093-14.489]; p=0.036). Stenting in Day 0-3 (13.2%; OR, 10.997 [95% CI, 2.333-51.826]; p=0.002) and Day 4-7 (8.3%; OR, 6.775 [95% CI, 1.382-33.227]; p=0.018) was associated with high risk for clinical events. However, the clinical event rates in stenting after 7 days from index event (Day 8-10, 1.8%; Day 11-14, 2.5%; Day 15-21, 0%; Day >21, 2.9%) were not different from that in stenting for asymptomatic stenosis. Overall radiological event rate (55.6%) in symptomatic stenosis was also higher than that in asymptomatic stenosis (35.5%; OR, 2.274 [95% CI, 1.553-3.352]; p<0.001). The high risk for radiological events was maintained in all time intervals (Day 0-3 : 55.3%; OR, 2.224 [95% CI, 1.103-4.627]; p=0.026; Day 4-7 : 58.3%; OR, 2.543 [95% CI, 1.329-4.949]; p=0.005; Day 8-10 : 53.6%; OR, 2.096 [95% CI, 1.138-3.889]; p=0.018; Day 11-14 : 57.5%; OR, 2.458 [95% CI, 1.225-5.021]; p=0.012; Day 15-21 : 55.6%; OR, 2.271 [95% CI, 1.099-4.764]; p=0.028; Day >21 : 54.8%; OR, 2.203 [95% CI, 1.342-3.641]; p=0.002). Conclusion : This study showed that as stenting was delayed, the periprocedural risk for clinical events decreased. The clinical event risk was high only in stenting within 7 days and comparable with that for asymptomatic stenosis in stenting after 7 days from index event, although the radiological event risk was not affected by stenting timing. Therefore, our results suggest that delayed stenting after 7 days from symptom onset is a safe strategy for symptomatic stenosis.

The Longitudinal Relationships between Depression and Smoking in Hardcore Smokers Using Autoregressive Cross-Lagged Modeling

  • Han, Jeong Won;Lee, Hanna
    • 대한간호학회지
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    • 제49권1호
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    • pp.69-79
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    • 2019
  • Purpose: This study aimed to identify the directionality of the causal relationship and interaction between depression and amount of smoking over time in hardcore smokers using longitudinal descriptive analysis. Methods: Secondary data from the Korean Welfare Panel Study were analyzed using autoregressive cross-lagged modeling. Participants included 342 hardcore smokers who participated in the 8th to 11th waves of the panel study. Results: Analyses revealed that change(s) in depression levels according to time had a significant positive relationship with the total amount of smoking per day (${\beta}=.29$, ${\beta}=.19$, ${\beta}=.17$, p<.001), while change(s) in total amount of smoking per day according to time had a significant positive relationship with depression (${\beta}=.43$, ${\beta}=.50$, ${\beta}=.38$, p<.001). Analysis of the cross-lagged effect between depression and total amount of smoking per day showed that depression at one time point had a significantly positive relationship with the total amount of smoking per day at the next time point (${\beta}=.14$, ${\beta}=.13$, ${\beta}=.13$, p=.021), and that the total amount of smoking per day at one time point had a significant positive relationship with depression at the next time point (${\beta}=.04$, ${\beta}=.04$, ${\beta}=.03$, p=.044). Conclusion: The findings in the present study confirmed a cross-interaction between depression and total amount of smoking per day in hardcore smokers. The present findings could be used to develop appropriate smoking-related interventions.

Rat체내 Sulfamethazine 경구투여 후 시간경과에 따른 간장, 신장 및 근육내 잔류함유량 측정 (Determination of sulfamethazine residues in liver, kidney and muscle according to the time lapsed after oral administration of sulfamethazine sodium to rats)

  • 도재철
    • 대한수의학회지
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    • 제36권3호
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    • pp.571-575
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    • 1996
  • Sulfamethazine sodium was orally administrated to Sprague Dawley female rats(body weight: 200~250g) with the sonde caude at the dose of 20mg of sulfamethazine sodium per 100g of body weight for 3 days to investigate the depletion rate of the drug from liver, kidney and muscle of rat. The results obtained were summerized as follows; 1. The mean concentrations of sulfamethazine in liver according to the time lapsed after oral administration of the sulfamethazine sodium were decreased from 1.27ppm at day 1 to 0.28ppm at day 4. 2. Sulfamethazine concentrations in kidney according to the time lapsed after oral administration of the sulfamethazine sodium were decreased from 0.77ppm at day 1 to 0. 12ppm at day 4. 3. The mean concentration of sulfamethazine in skeletal muscle according to the time lapsed after oral administration of the sulfamethazine sodium was at or below 0.09ppm within 4 days after withdrawl of medicated solution.

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공립유치원의 오후 재편성 종일반 운영에 따른 교사와 유아의 어려움에 대한 질적 연구 (A Qualitative Study on Difficulties of Teachers and Young Children in the Operation of the Full day Public Kindergarten Classes Regrouped in the Afternoon)

  • 서현;이승은
    • 한국생활과학회지
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    • 제17권3호
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    • pp.399-411
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    • 2008
  • The study purposes to survey teacher's and child's difficulties which full day classes of public kindergarten regrouped in the afternoon time are having. The subjects are 4 full day class pre-service kindergarten teachers and 8 full-day class children in G Metropolitan City and in J Province. Data were collected through in depth interviews and participatory observation. According to the results, the variables of teachers' difficulties in managing full day classes regrouped in the afternoon time are "living as an outsider without a sense of belonging", "living as a false teacher rather than a real class teacher", and "living as a teacher giving specialty and aptitude education". The variables of children's difficulties are "moving like a migratory bird", "watching the clock and the door", and "being unable to concentrate". The study is expected to be useful as one of basic findings for desirable management of kindergarten full day classes regrouped in the afternoon time.

주5일 근무제에 따른 직장인의 여가 만족 (Workers' Leisure Satisfactions on Them after Enforcement of 5-day Work Week System)

  • 박성연;이기영
    • 가족자원경영과 정책
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    • 제11권4호
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    • pp.137-154
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    • 2007
  • These days, people have changed their attitude and understanding of the tenn leisure. Since the introduction of the five-day work week system in Korea, people's leisure activities have changed greatly. The purpose of this study was to examine how leisure activities have changed after the introduction of the five-day work week and to find out the variables which influence the way Koreans spend their leisure time. The conclusion and results of these analyses are follows: The five-day work week system increased people's leisure hours, but they were still working more than 40 hours per week and their satisfaction from leisure activities was more influenced by other variables than the enforcement of the five-day work week system. Among the variables influencing the satisfaction from leisure, only those with high income and educational backgrounds were affected by the five-day work week. To conclude, there is a necessity for direction suggestions and political support to utilize leisure time positively.

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개에서 Propofol의 연속투여효과 (Effects of Continuous Administration of Propofol in Dogs)

  • 권영삼;장광호;김정은;채형규;임재현;이근우;장인호
    • 한국임상수의학회지
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    • 제16권2호
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    • pp.363-368
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    • 1999
  • The effects of continuous administration of propofol on the blood, liver and kidney of dogs were evaluated. Propofol(5mg/kg) was repeatedly administered to 8 mongrel dogs intravenously for consecutive seven days. Time to recovery, body temperature, heart rate, and respiratory rate were measured and recorded during experimental period. Hematology (WBC, RBC, PCV) and serum chemistry (AST, ALT, BUN, Creatinine) were also monitored for eight days. Time to standing significantly decreased on day 4 and 6 compared with that on day 1. Body temperature 5 minutes after injection on day 5 and 6, and respiratory rate before injection on day 2, 3, 5 and 6 were significantly increased, respectively. No significant changes were observed in total WBC counts, total RBC counts and PCV values. The AST and AIT values were decreased on day 2 compared with those on day 1, but were within clinically normal range. There were no significant changes in BUN and Creatinine levels. This study suggests that consecutive day propofol anesthesia in dogs can be used for the purpose of the treatment and restraint.

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생산직 취업모의 탁아서어비스의 요구 및 그들을 위한 탁아제도에 관한 연구 (A Study on the Need of Child-care Service and Child-care Programs for the Working Class Mothers)

  • 정민자
    • 대한가정학회지
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    • 제28권1호
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    • pp.125-140
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    • 1990
  • The purpose of this study is to inverstigate the need of child care services and child care programs for the working class mothers. We surveyed four Industrial complex (in Seoul, Incheon, Pusan, Ulsan) to collect data. The samples were 282 mothers (Seoul: 95, Incheon: 54, Ulsan: 62, Pusan: 71). The mothers had children under six years of age and they worked at factory for 11 hours. They (65%) rented houses with 1-2 rooms. Their income was not enought to support their family. They were never supported by social network, so they had to work at factory and they need child care services. The mothers had many difficulties of child rearing and early childhood education. They wanted perfect day care programs. They expected it as followings: (1) Day care center placed at factory or near home. (2) The administrater is goverment or employer. (3) It is managed a full time system. (4) It is center-based day care or industrical day care. (5) They share day care expense with employer or goverment. (6) Day care expenses is 35,000 won in case of full time system, 25,000 won in case of half-time system. They desited highly qualifed day care programs, but they would not expense highly cost. So we suggest that goverment and factory employers support the working mothers.

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신속개방형 콘크리트 도로포장재의 설계를 위한 실험실적 평가 연구 (A Study on Design of High Early Strength Cement and Concrete for Road Way Pavements)

  • 임채용;엄태선;신국재;이종열;엄주용;조윤호
    • 한국콘크리트학회:학술대회논문집
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    • 한국콘크리트학회 2001년도 봄 학술발표회 논문집
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    • pp.295-300
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    • 2001
  • In road pavements, it is known that cement concrete pavement has superior durability, safety in compared with asphalt concrete pavement. But in reparing pavement cement concrete pavement is not usually applied because of the length of time while the road is interrupted when using Ordinary and Rapid-hardening Portland Cement. And Super High Early Strength Cement and Ultra Super High Early Strength Cement are not favorable for ready mixied concrete because of rapid setting time, high slump loss and other restrictions. We aim to develope specific cement and concrete developing 1 day strength of over 300 kg/$cm^{2}$ to open the road within one day and workable time is maintained over 1 hour that can be used as ready mixed concrete. In this study, we Produced cement using rapid-hardening cement, Hauyne clinker, anhydride gypsum and accelerator and studied on its properties. The concrete strength was over 300 kg/$cm^{2}$ at 1 day and 550 kg/$cm^{2}$ at 28 day and workable time was maintained for over 1 hour.

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성인 여성에서 커피 섭취와 허리둘레를 기준으로 한 비만과의 관련성 - 2012~2016 국민건강영양조사 자료를 이용하여 - (Coffee Consumption and the Risk of Abdominal Obesity as Defined by Waist Circumference in Korean Women - Based on 2012~2016 Korea National Health and Nutrition Examination Survey -)

  • 연지영;배윤정
    • 한국식품영양학회지
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    • 제32권1호
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    • pp.69-78
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    • 2019
  • We investigated coffee consumption in relation to the abdominal obesity as defined by waist circumference in Korean women aged 19~64 years, using data from the National Health and Nutrition Examination Survey 2012~2016. The participants to the study were classified according to 3-in-1 coffee consumption level (none-coffee, ${\leq}1$ time/day of 3-in-1 coffee, >1 time/day of 3-in-1 coffee) by a food frequency questionnaire. The analysis was conducted by the following age groups: <50 years and $50{\leq}$ years. The 3-in-1 coffee consumption group had significantly more smokers and more alcohol consumption frequency as compared to the none-coffee group. The energy intake from the participants in the 3-in-1 coffee consumption of ${\leq}1$ time/day of 3-in-1 coffee group, and >1 time/day of 3-in-1 coffee group were 131.2 kcal/day and 123.1 kcal/day. In the 50 years or over age group, >1 time/day of 3-in-1 coffee group was at a lower risk of abdominal obesity as defined by waist circumference, compared with the non-coffee group multivariable adjustment (OR: 0.44, 95% CI: 0.25~0.77). Our findings suggest that the 3-in-1 coffee consumption may be related to abdominal obesity as defined by waist circumference in Korean females aged 50 years or over.

흰쥐에 있어서 부신척출이 성선, 갑상선 및 혈청성분에 미치는 영향에 관한 연구 (Effects of Adrenalectomy on Sexual Gland, Thyroid Gland and Serum Components in Rats)

  • 신광순
    • 한국가축번식학회지
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    • 제5권1호
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    • pp.43-63
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    • 1981
  • This study aimed to determine the effects of adrenalectomy on the sexual gland, the thyroid gland and the serum components. A total of 192 Wister strain albino rats were evenly divided into 4 sexually equal groups for the comparisons. Each groups was divided into a control and a treatment group by sexuality. Each tissue of the sexual gland and the thyroid gland was microscopically examined, and at the same time body weight and serum components were also examined on the 1st, 7th, 14th, 28th, 42nd, 56th, 70th and 84th day respectively following adrenalectomy. The results obtained were as follows: 1. The body weight was sufficiently retarded in decreasingly after the adrenalectomy as compared to that of control. 2. The histological change of testis started atrophy of spermatogonia and degeneration of spermatocyte. There was a, pp.ared no cell division activity. Spermatozoa in the seminiferous tuble was not noticed but degeneration of interstitial cell was started and spermatozoa in the epididymal duct disa, pp.ared. 3. Degeneration of oocyte and follicular cell was noticed as the histological change of ovary. There was not a, pp.arance of primary follicle and corpus Iuteum but interstitial cell was proliferated. 4. For the effect of adrenalectomy on the histological change of the thyroid gland, the number of small follicle decreased and that of large follicle increased as the time passed following the adrenalectomy. And the follicular epithelial cell became squamous as typical condition of functional decreased. 5. It was shown that in the total contents of serum protein no difference with control occurred with in the 70th day for male and female adrenalectomized, respectively. But the differences in protein contents were significanly decreased on the 70th day. 6. No difference occurred in the total serum lipids on the 7th day, but they decreased significantly on the 42nd day, and (P<0.01) on the 56th, and 70th day. A tendency to decrease was noted as time elapsed following adrenalectomy. 7. Increase and decrease were intercrossed in the serum cholesterol contents between the control and th treatment groups on the 28th day. But the difference significantly decreased on the 42nd, 56th, and 70th day after adrelalectomized. The contents showed tendency to decrease as time elapsed following adrenalectomy. 8. The blood glucose contents rapidly decreased with time. The difference were significant on the 28th and 42nd day, and highly significant on the 56th and 70th day for male adrenalectomized. 9. In case of solium, there was no noticeable sexual distinction. There was slight in creasing or decreasing for the control group. But the treatment group tended continuously to decrease for male and female. 10. It was shown that potassium contents tended to increase on the 28th day for male and female, but the differences were small. 11. As for chlorine, it tended to decrease rapidly on 7th day for male and female adrenalectomized, and the tendency continued.

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