• Journal of Broadcast Engineering
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• v.25 no.4
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• pp.569-575
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• 2020

The serial arc is one of factors causing electrical fires. Over past decades, various researches have been carried out to detect arc occurrences. Even though frequency analysis, wavelet, and statistical features have been used, additional steps such as transformation and feature extraction are required. On the contrary, deep learning models directly use the raw data without any feature extraction processes. Therefore, the usage of time-domain data is preferred, but the performance is not satisfactory. To solve this problem, subsequent 1-D signals are transformed into 2-D data that can feed into a convolutional neural network (CNN). Experiments validated that CNN model outperforms deep neural network (DNN) by the classification accuracy of 8.6%. In addition, data augmentation is utilized, resulting in the accuracy improvement by 14%.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.4
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• pp.1343-1348
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• 2015

Human UHRF1 (ubiquitin-like PHD and RING finger domain-containing 1) has been reported to be over-expressed in many cancers, but its role in ovarian cancer remains elusive. Here, we determined whether knockdown of UHRF1 by lentivirus-mediated shRNA could inhibit ovarian cancer cell growth. Lentivirus-mediated short hairpin RNAs (lv-shRNAs-UHRF1) were designed to trigger the gene silencing RNA interference (RNAi) pathway. The efficiency of lentivirus-mediated shRNA infection into HO-8910 and HO-8910 PM cells was determined using fluorescence microscopy to observe lentivirus-mediated GFP expression and was confirmed to be over 80 percent. UHRF1 expression in infected HO-8910 and HO-8910 PM was evaluated by real-time PCR and Western blot analysis. The Cell Counting Kit-8 (CCK-8) assay was used to measure cell viability; flow cytometry and Hoechst 33342 assay was applied to measure cell cycle arrest and apoptosis. Cell invasion was assessed using transwell chambers. Our results demonstrated that the loss of UHRF1 promoted HO-8910 and HO-8910 PM cell apoptosis, while inhibiting cell proliferation. In addition, UHRF1 knockdown significantly inhibited the invasion of human ovarian cancer cells. In the present study, we also showed that depleting HO-8910 cells of UHRF1 caused activation of the DNA damage response pathway, with the cell cycle arrested in G2/M-phase. The DNA damage response in cells depleted of UHRF1 was illustrated by phosphorylation of CHK (checkpoint kinase) 2 on Thr68, phosphorylation of CDC25 (cell division control 25) on Ser 216 and phosphorylation of CDK1 (cyclin-dependent kinase 1) on Tyr 15.

• BMB Reports
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• v.31 no.2
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• pp.111-116
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• 1998

HLA-DR4 is the dominant allele of MHC class II genes in Koreans. In particular, the $DRB1^*0405$ subtype has been reported to be almost exclusively expressed in Far East Asians, and has also been observed to be strongly associated with rheumatoid arthritis in Koreans and the Japanese. Identification of this specific allele has been mainly performed by PCR-based methods, which is often time consuming, costly, and involves tedious procedures such as the isolation of genomic DNA, PCR, and gel electrophoresis. To develop a more convenient tool for screening vast amounts of samples as well as to generate reagents which might also be used in other applications, in this study, antibodies were produced against this specific HLA subtype. By PCR, an allelespecific region covering the ${\beta}1$ domain of $DRB1^*0405$ was amplified and recombinantly expressed in E.coli. Immunization of Lewis rats with the purified protein yielded an allele specific antiserum. Western blot analysis showed the selective detection of the HLA-DR ${\beta}-chain$. Using this antiserum, established cell lines and peripheral blood lymphocytes were analyzed on their HLA haplotype by fluorescence activated flow cytometry. These novel antibodies will provide a powerful tool in the detection and investigation of DR4 alleles.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.33 no.6A
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• pp.676-684
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• 2008

In digital video broadcasting-terrestrial (DVB-T), which is the European digital terrestrial television standard, the orthogonal frequency division multiplexing (OFDM) has been adopted for signal transmission. The main reasons using OFDM are to increase the robustness against the frequency selective fading and impulse noise, and to use available bandwidth efficiently. However, channel variation within an OFDM symbol destroys orthogonality between subcarriers, resulting in inter-carrier interference (ICI), which increases an error floor in proportional to maximum Doppler spread. This paper provides an ICI analysis in both time and frequency domains while existing literatures analyze the ICI effects mainly in frequency domain and proposes the algorithms that estimate the channel impulse response and channel variation using least square (LS) algorithm which is the most simple channel estimation technique. And we propose adaptive channel estimation algorithm that estimates the velocity of terminals. The simulation results show that proposed algorithm has similar performance with about 1.5% computational complexity of noise and ICI reduction LS algorithm in low speed environments.

• The Journal of the Korea Contents Association
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• v.6 no.1
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• pp.1-7
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• 2006

This paper proposes a new method that reduces the complexity of the combined system, which consists of the selective mapping(SLM) and the partial transmit sequence(PTS) in the Orthogonal Frequency Division Multiplexing(OFDM). In order to reduce the Peak-to-Average Power Ratio(PAPR), many techniques have been developed such as SLM and PTS. and their combined systems. However the method that simply combines PTS and SLM to improve the effectiveness of a system increases the complexity of calculation. The scheme employed in this research suggests a system that combines PTS and SLM reducing the complexity via the N($N=2^n$)-point inverse fast Fourier transforms(IFFT), which uses the decimation in time domain not only to improve PAPR but also to reduce the amount of calculation. The proposed method reduces the complexity by multiplying a phase sequence and a subblock index to the data sequences in the middle of IFFT, which yields an optimal sequence with minimal PAPR. The superiority of the proposed method is demonstrated by simulation results and analysis.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.41 no.6
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• pp.483-489
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• 2017

An ultrasonic technique was developed to characterize the resonance behavior of a microcantilever operating in a megahertz regime. A high-power ultrasonic pulser and a contact transducer were employed to excite the silicon microcantilever, and a Michelson interferometer was used to obtain the time domain waveform. The natural frequency of the microcantilever was evaluated through the fast Fourier transform of the signal, and a numerical analysis using the finite element method confirmed the measurement data. The present study proposes a novel and facile method to evaluate nanoscale materials and structures with high sensitivity compared to conventional approaches.

• Journal of Animal Science and Technology
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• v.54 no.3
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• pp.157-163
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• 2012

The male reproduction is precisely controlled by a number of intrinsic and extrinsic factors. These factors usually involve in expressional regulation of various molecules influencing on sperm production in the testis. A number of ways are employed to control the transcription of specific genes, including epigenetic modifications of DNA and histone molecules. DNA methylation of CpG dinucleotides is a commonly used regulatory mechanism for testicular genes associated with the fertility. Previous studies have demonstrated the infertility induced by improper DNA methylation of these genes. In the present research, we attempted to determine transcriptional expression of some of these genes in the rat testis at different postnatal ages using real-time PCR analysis. These genes include neurotrophin 3 (Ntf3), insulin-like growth factor II (Igf2), JmjC-domain-containing histone demethylase 2A 1 (Jhm2da), paired box 8 transcription factor (Pax8), small nuclear ribonucleoprotein polypeptide N (Snrpn), and 5,10-methylenetetrahydrofolate reductase (Mthfr). The expression levels of Ntf3, Igf2, and Snrpn genes were the highest at the neonatal age, followed by transient decreases at the prepubertal age. Expression of Jhm2da and Mthfr genes were continuously increased from the neonate to 1 year of age. The levels of Pax8 mRNA at the early ages were higher than those at the later ages of postnatal development. These findings suggest that expression of some fertility-associated testicular genes in the rat during postnatal period could be differentially regulated by the control of the degree of DNA methylation.

• Journal of the Korea institute for structural maintenance and inspection
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• v.22 no.1
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• pp.48-55
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• 2018

The purpose of the present study is to compare the reduction rate of natural frequency and the increase rate of damping parameter with structural damage in system. For this purpose, experiment and numerical simulation analysis are performed for the 2-span H-Beam with lower natural frequency and higher damping parameter from free vibration in structure. The response signal by impact load before and after damage is analyzed at 14 locations. The response signals for all locations are performed fast fourier transform to estimate the natural frequency reduction rate and wavelet transform to estimate the damping parameter increase rate. The time domain function corresponding to each scale(frequency) is separated from the response signal by wavelet parameter. The estimation of damping parameter increase rate using wavelet transform is more sensitive than the estimation of natural frequency reduction rate in structure.

• Journal of The Korean Digital Architecture Interior Association
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• v.12 no.3
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• pp.49-58
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• 2012

In Regarding urban geo-spatial information visualization in this study, visualization of physical attribute information is mostly related to the representation of spatial domain and physical objects, and visualization of non-physical attribute information has to do with visualizing citizens and their activity information in the physical environment. In particular, a citizen, one of the non-physical information attributes, is characterized by a constant mobility in the physical environment, and thus visualization of his/her activity information is vital in conveying information because this information may not be depicted with any given, fixed figures. In consideration of this difficulty, this study integrates interrelationship among urban space, human needs, social relations, and lifestyles into a 'high-tech' service where experience in time and space is possible. To analyze the web-service and visualization cases, the study has selected visualization indicators consisting of information representation objective, information representation means, and information representation result. The results of the case analysis through specific indicators set a range in information representation objective, means, and result, thereby forming a user-friendly environment in which representational results are readily available to users, and ultimately expanding the users' selection range coming with a variety of options. This study also assumes that a wide range of service provision is needed to reflect users' needs in developing urban geo-spatial service model, and the display of its results should visualize users' satisfaction to construct the best information needed to users.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.8 no.5
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• pp.516-524
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• 1997

The propagation properties of various pulse signal types(square pulse, Gaussian pulse, trapezoid pulse, RF pulse) on coupled microstrip lines are investigated. Numerical integration technique which has its accuracy and is easily simulated, is used to obtain the time domain response of pulse signals. Frequency-dependent characteristics of coupled microstrip line is obtained using Jansen's approximate equation. The propagation properties of pulse signal on coupled microstrip lines is analyzed regarding to its geometric structure (relative permittivity ${varepsilon}_r$ substrate height h, strip width w of the microstrip line) and pulse width ${\tau}$ of signal pulse. The simulation results show that space between two lines is very significant parameter in pulse distortion in comparison of any other parameters. The results of this paper are compatible to the trade-off determination of relative permittivity, substrate height, strip width and pulse width of signal pulse when a design of MIC and MMIC is necessary.