• 가정과삶의질연구
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• 제27권3호
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• pp.31-43
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• 2009

Using the first wave of KLoSA(Korean Longitudinal Study of Ageing) beta version, this study analyzed factors affecting early retired men's subjective life satisfaction through Binary Logit and Multiple Regression. Total 552 men were selected as a sample. The main results of empirical analysis in this study were as follows: The retirement reason(health-) and monthly household income(+) affected whether they were satisfied with the retirement life or not and subjective life satisfaction over all. Especially, the retirement reason(health-) had a stronger effect on whether early retired min were satisfied with the retirement life or not and their subjective life satisfaction than monthly household income revealed significant variable in previous studies. This result represents that the retiree's life satisfaction analysis model must include retiree's characteristics at the time of retirement as well as retiree's current status characteristics or socio-economic characteristics.

• Nuclear Engineering and Technology
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• 제49권1호
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• pp.141-147
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• 2017

Mechanical shim is an advanced technology for reactor power and axial offset control with control rod assemblies. To address the adverse accuracy impact on the ex-core power range neutron flux measurements-based axial offset control resulting from the variable positions of control rod assemblies, the lead-lag-compensated in-core self-powered vanadium detector signals are utilized. The prompt ${\gamma}$ current of self-powered detector is ignored normally due to its weakness compared with the delayed ${\beta}$ current, although it promptly reflects the flux change of the core. Based on the features of the prompt ${\gamma}$ current, a method for configuration of the lead-lag dynamic compensator is proposed. The simulations indicate that the method can improve dynamic response significantly with negligible adverse effects on the steady response. The robustness of the design implies that the method is of great value for engineering applications.

• Clinical and Experimental Pediatrics
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• 제50권6호
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• pp.580-584
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• 2007

다발성 경화증은 중추신경계 백질의 여러 부위를 시간 간격을 두고 침범하는 만성재발성 질환이다. 주로 20세에서 40세 사이에 발병하며 15세 이하 소아에서도 3-5% 정도 발병하는 소아기에는 매우 드문 질환이다. 원인은 아직 정확히 밝혀지지 않았으나 유전적, 환경적 및 감염과 연관된 자가면역반응 등 여러요인이 복합적으로 작용하는 것으로 생각하고 있다. 임상증상은 침범된 백질 부위에 따라 다양한데 사지근력 약화나 저림, 시력장애, 감각장애, 운동실조 등 다양한 증세로 호전과 재발을 반복한다. 본 저자들은 경련, 왼쪽 편마비 등의 증상으로 6세에 첫 발병 후 메틸프레드니솔론(methylprednisolon) 치료 후 증상 완전 회복 있었으나 6개월 후 경련, 두통, 왼쪽 안와주위 통증 등으로 다시 입원하는 등 4년간 추적 관찰 중 4차례 메틸프레드니솔론 치료 실시하였으나 다른 양상의 신경학적 증상으로 재발하여 Interferon-${\beta}$-1b($Betaferon^{(R)}$, SheringAG, Germany) 예방 치료를 실시한 다발성 경화증 환자 1례를 경험 하였기에 문헌 고찰과 함께 보고하는 바이다.

• 자원ㆍ환경경제연구
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• 제22권1호
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• pp.99-125
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• 2013

신재생에너지 산업은 유망한 미래를 가지고 있지만 아직 미성숙한 산업의 특성상 높은 리스크를 지니고 있다. 국내 신재생에너지 산업의 성장을 위해서는 국내의 신재생에너지 기업들의 리스크 요인들을 파악하고 그것들을 저감시켜 줄 수 있는 방안을 찾는 것이 중요하다. 따라서 본 연구에서는 국내 신재생에너지 기업들을 대상으로 리스크 요인을 파악하고 리스크를 감소시킬 수 있는 방안을 찾아보고자 하였다. 본 연구에서는 기업의 리스크를 주가의 관점에서 시장 주가의 변동 대비 기업 주가의 변동 정도로 파악하여 연구를 진행하였다. 분석결과 국내 신재생에너지 기업의 리스크에 영향을 미치는 기업 내부 요인들을 찾았다. 분석 결과 기업의 규모, 기업의 부채 비율의 증가율, 기업의 다각화 수준이 유의한 결과를 나타내었다. 기업의 규모가 클수록 기업의 리스크는 감소하는 것으로 나타났으며, 기업의 부채 비율의 증가율과 다각화 수준이 높을수록 기업의 리스크는 증가하는 것으로 나타났다. 두 번째로 기업 외부 요인 중 높은 풍력 및 태양광 국내 설치량 증가율과 높은 정부 R&D 지원의 증가율이 신재생에너지 기업의 리스크를 감소시킴을 확인하였다. 세 번째로 각 요소들의 신재생에너지 기업의 리스크에 대한 상대적 영향도를 파악하였다. 민감도 분석 결과 신재생에너지 기업의 리스크에 영향을 미치는 요소들은 국내 연간 설치량 증가율, 사업규모 또는 기업의 사업다각화 수준, 부채 비율 증가율, 정부 R&D 지원 증가율 순으로 그 영향도가 큰 것으로 나타났다.

• 한국치위생학회지
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• 제9권3호
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• pp.415-425
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• 2009

Objectives : In this study, the dental treatment satisfaction degree of the patients, who experienced the sleep dental treatment or non-sleep dental treatment, the revisit rate and the differences among the encouraging intention were compared and analyzed, and the primary factors through which the satisfaction degree of sleep dental treatment has influence on the revisits and the encouraging intention were analyzed, and the proposal was made on clinic management to raise qualitative medical service level on the basis of this study. Methods : The questionnaires filled out by the 202 users of a certain dental clinic located in Pohang-si, Gyeongbuk were analyzed. The frequency analysis and the crosstabulation analysis of the general characteristics of survey participants were carried out, and the satisfaction difference between the sleep dental treatment and the non-sleep dental treatment was identified with the t-test analysis. The multiple regression analysis were carried out to identify the factors through which the sleep dental treatment has influence on the through which the satisfaction degree of sleep dental treatment has influence on the satisfaction degree of the medical service and the revisited dentists. Results : In the medical service satisfaction degree in general, the sleep dental treatment had the higher meaningful value than the non-sleep dental treatment(p<0.05). In the case of the difference in satisfaction degree on each medical service factor, the satisfaction of the sleep treatment group was high in every case, but the meaningful difference showed up in the factors of waiting time, treatment procedure, revisit and the encouraging intention(p<0.01). The revisit to the sleep treatment dental clinic and the recommending dentist increased in proportion to the satisfaction degree of sleep dental treatment, and the Beta value appeared to be 0.337 at the influence of the subordinate variable(p<0.001). As for the influence on the sleep dental treatment satisfaction, the Beta value of the dental hygienist was the highest, marking the value at 0.375(p<0.01). As for the satisfaction of the patients who experienced the sleep dental treatment, the Beta value of the treatment fee was the highest, marking 0.352(p<0.001), in the multiple regression analysis of the revisit and the encouraging intention, and the 0.156 of dentist factor and the 0.152 of treatment procedure and waiting time showed lower regression coefficient(p<0.05). Conclusions : It is assumed that the satisfaction degree of sleep dental treatment, which is carried out as a new dental service has influence on the increase of revisit to the dental clinic as an important factor. But it was disclosed that the high level of treatment fee has the biggest influence on choice of revisit to the dental clinic. In the current medical charge system, the sleep dental treatment appeared to have a big influence on raising the quality of dentists, the satisfaction of patients, the revisit and encouraging intention, and also the roles of the dental hygienist was important. It is assumed that these facts are functioning as the factors that are linked to the increase of revisit and the encouraging intention.

• Applied Biological Chemistry
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• 제48권4호
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• pp.352-357
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• 2005

건강기능성식품의 원료로 이용되고 있는 석류의 주요성분에 대한 효율적인 이용을 위하여 반응표면분석에 의하여 각 성분의 열수 추출조건을 분석하여 최적 추출조건을 확립하였다. 주요성분의 최적 추출조건 예측을 위하여 추출온도$(60{\sim}100^{\circ}C)$, 추출시간$(1{\sim}5hr)$을 독립변수로 하여 중심합성계획에 의해 10구의 추출조건을 설정하였다. 각 추출물의 주요성분 함량 즉, chlorogenic acid, kaempferol, $17-{\alpha}-estradiol$ 및 $17-{\beta}-estradiol$ 함량을 측정하여 SAS program에 의해 회귀분석을 하여 각각의 특성을 분석하였다. 그 결과 chlorogenic acid, kaempferol 및 $17-{\alpha}-estradiol$ 함량은 주로 추출온도에 영향을 받는 것으로 나타났으며, $17-{\beta}-estradiol$ 함량은 추출시간에 영향을 받는 것으로 나타났다. 각 변수에 대한 회귀식을 도출하여 공정인자별 석류 추출물의 chlorogenic acid, kaempferol, $17-{\alpha}-estradiol$ 및 $17-{\beta}-estradiol$ 함량에 대한 최적 추출조건을 superimpose한 결과 추출온도 $98{\sim}100^{\circ}C$, 추출시간 $3{\sim}4hr$로 각각 예측되었다.

• Journal of Microbiology and Biotechnology
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• 제16권6호
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• pp.889-895
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• 2006

To investigate the antibiotic-resistant patterns and the gene types of extended-spectrum $\beta$-lactamase (ESBL)-producing Klebsiella pneumoniae, we collected 226 Klebsiella pneumoniae strains from three general hospitals with more than 500 beds in Busan, Korea from September 2004 to October 2005, The minimum inhibitory concentration (MIC) of antibiotics was measured using the Gram-negative susceptibility (GNS) cards of Vitek (Vitek system, Hazelwood Inc., MO, U.S.A.). Of the 226 K, pneumoniae isolates, 65 ESBL-producing K. pneumoniae strains were detected by the Vitek system and confirmed by the double-disk synergy test. TEM (Temoniera) type, SHV (sulfhydryl variable) type, and CTX-M (cefotaxime) type genes were detected by polymerase chain reaction. All 65 K. pneumoniae strains were resistant to ampicillin, cefazolin, cefepime, ceftriaxone, and aztreonam, and 83.0% of the organisms were resistant to ampicillin/sulbactam, 66.1% to tobramycin, 67.6% to piperacillin/tazobactam, 61.5% to ciprofloxacin, and 47.6% to trimethoprim/sulfamethoxazole, and 43.0% to gentamicin. TEM-type ESBLs (TEM-1 type, -52 type) were found in 64.6% (42 of 65) of the isolates, SHV-type ESBLs (SHV-2a type, -12 type, -28 type) in 70.7% (46 of 65) of isolates, and CTX-M-type ESBLS (CTX-M-15 type) in 45% (29 of 65) of isolates. Of the 65 ESBL-producing K. pneumoniae strains, two strains were found to harbor blaSHV-28, which were detected in Korea for the first time. Therefore, more investigation and research on SHV-28 are needed in order to prevent the ESBL type-producing K. pneumoniae from spreading resistance to oxyimino cephalosporin antibiotics.

• 천문학회보
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• 제41권1호
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• pp.41.2-41.2
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• 2016

The follow-up BVRI photometric observations of NSVS 1461538, which was discovered as an $Algol/{\beta}$ Lyr eclipsing variable by Hoffman, Harrison & McNamara (2009), were performed for three years from 2011 to 2013 by using the 61-cm telescope and CCD cameras of Sobaeksan Optical Astronomy Observatory (SOAO). New light curves have deep depths both of the primary and secondary eclipses, rounded shapes outside eclipses and a strong O'Connell effect, indicating that NSVS 1461538 is a typical W UMa close binary system rather than an $Algol/{\beta}$ Lyr type binary star. A period study with all the timings shows that the orbital period may vary in a sinusoidal way with a period of about 5.6 yr and a small semi-amplitude of about 0.008 d. The cyclical period variation was interpreted as a light-time effect due to a tertiary body with a minimum mass of $0.66M{\odot}$. The first photometric solution with the Wilson-Devinney binary model shows that the system is a W-subtype contact binary with the mass ratio ($q=m_c/m_h$) of 3.46, orbit inclination of 85.6 deg and fill-out factor of 30%. From the existing empirical relationship between parameters, the absolute dimension was estimated. The masses and radii of the component stars are $0.28M{\odot}$ and $0.71R{\odot}$ for the less massive but hotter primary star, respectively, and $0.96M{\odot}$ and $1.21R{\odot}$ for the more massive secondary, respectively. Possible evolution of the system is discussed in the mass-radius and the mass-luminosity planes.

• ALGAE
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• 제31권2호
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• pp.167-174
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• 2016

Biological response of cells to variable conditions should affect the expression level of certain genes. Quantification of these changes in target genes needs stable internal controls. Real-time quantitative polymerase chain reaction (PCR) has traditionally used reference or ‘housekeeping’ genes, that are considered to maintain equal expression in different conditions, to evaluate changes in target genes between samples and experimental conditions. Recent studies showed that some housekeeping genes may vary considerably in certain biological samples. This has not been evaluated in red algae. In order to identify the optimal internal controls for real-time PCR, we studied the expression of eleven commonly used housekeeping genes; elongation factor 1-alpha, glyceraldehyde-3-phosphate dehydrogenase, β-actin, polyubiquitin, 30S ribosomal gene, 60S ribosomal gene, beta-tubulin, alpha-tubulin, translation initiation factor, ubiquitin-conjugating enzyme, and isocitrate dehydrogenase in different life-history stages of Bostrychia moritziana. Our results suggest that glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and 30S ribosomal gene, have the most stable gene expression levels between the different life history stages (male, female, carposporophyte, and tetrasporophyte), while the other genes are not satisfactory as internal controls. These results suggest that the combinations of GAPDH and 30S would be useful as internal controls to assess expression level changes in genes that may control different physiological processes in this organism or that may change in different life history stages. These results may also be useful in other red algal systems.

• 천문학논총
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• 제27권5호
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• pp.399-409
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• 2012

NGC 6871을 중심으로 시계열 관측한 Cyg OB3 성협영역에서 모두 15개의 단주기 변광성을 찾았다. 이들은 모두 국부나선팔에 속한 ${\delta}$ Scuti 형 변광성으로 보인다. 그림 5의 영연령주계열 상에서 밝은쪽에 속한 V1-V4는 분광형이 모두 A, F 형으로서 Cyg OB3 성협보다 먼 거리에 있는 ${\beta}$ Cephei 형 변광성이라기 보다는 국부나선팔의 앞쪽에 놓인 ${\delta}$ Scuti 형 변광성이었다. 15개의 ${\delta}$ Scuti 형 변광성 중에는 2개(V1과 V3)는 GCVS에 ${\delta}$ Scuti 형 변광성으로 분류되어 이미 알려진 변광성이고, 나머지는 모두 새로 발견한 것이다. 새로 발견한 변광성 중에는 한 개의 이중모드 ${\delta}$ Scuti 형 변광성(V3)과 2개의 HADS 변광성(V13과 V14)이 포함되었다. 시계열 관측과는 별도로 표준화 관측을 수행하여 관측 영역의 색-등급도를 얻었는데 그림 6에서 Massey etal.(1995)의 결과와 잘 맞았다.