• Title/Summary/Keyword: Time slice

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5-Hydroxytryptamine Inhibits Glutamatergic Synaptic Transmission in Rat Corticostriatal Brain Slice

  • Cho, Hyeong-Seok;Choi, Se-Joon;Kim, Ki-Jung;Lee, Hyun-Ho;Kim, Seong-Yun;Cho, Young-Jin;Sung, Ki-Wug
    • The Korean Journal of Physiology and Pharmacology
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    • v.9 no.5
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    • pp.255-262
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    • 2005
  • Striatum is involved in the control of movement and habitual memory. It receives glutamatergic input from wide area of the cerebral cortex as well as an extensive serotonergic (5-hydroxytryptamine, 5-HT) input from the raphe nuclei. In our study, the effects of 5-HT on synaptic transmission were studied in the rat corticostriatal brain slice using in vitro whole-cell recording technique. 5-HT inhibited the amplitude as well as frequency of spontaneous excitatory postsynaptic currents (sEPSC) significantly, and neither ${\gamma}-aminobutyric$ acid (GABA)A receptor antagonist bicuculline (BIC), nor $N-methyl-_{D}-aspartate$ (NMDA) receptor antagonist, $_{DL}-2-amino-5-phosphonovaleric$ acid (AP-V) could block the effect of 5-HT. In the presence non-NMDA receptor antagonist, 2,3-dioxo-6-nitro-1,2,3,4-tetrahydrobenxo[f] quinoxaline-7-sulfonamide (NBQX), the inhibitory effect of 5-HT was blocked. We also figured out that 5-HT change the channel kinetics of the sEPSC. There was a significant increase in the rise time during the 5-HT application. Our results suggest that 5-HT has an effect on both pre- and postsynaptic site with decreasing neurotransmitter release probability of glutamate and decreasing the sensitivity to glutamate by increasing the rise time of non-NMDA receptor mediated synaptic transmission in the corticostriatal synapses.

Hardware Implementation of RUNCODE Encoder for JBIG2 Symbol ID Encoding (JBIG2 심벌 ID 부호화를 위한 런코드 부호기의 하드웨어 구현)

  • Seo, Seok-Yong;Ko, Hyung-Hwa
    • Journal of Advanced Navigation Technology
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    • v.15 no.2
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    • pp.298-306
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    • 2011
  • In this paper, the RUNCODE encoder hardware IP was designed and implemented for symbol ID code length encoding, which is one of major modules of JBIG2 encoder for FAX. ImpulseC Codeveloper and Xilinx ISE/EDK program are used for the hardware generation and synthesis of VHDL code. The synthesized hardware was downloaded to Virtex-4 FX60 FPGA on ML410 development board. The synthesized hardware utilizes 13% of total slice of FPGA. Using Active-HDL tool, the hardware was verified showing normal operation. Compared with the software operating using Microblaze cpu on ML410 board, the synthesized hardware was better in operation time. The improvement ratio of operation time between the synthesized hardware and software showed about 40 times faster than software only operation. The synthesized H/W and S/W module cooperated to succeed in compressing the CCITT standard document.

Extracting Frequency-Frequency Correlation Function from Two-Dimensional Infrared Spectroscopy: Peak Shift Measurement

  • Kwak, Kyung-Won
    • Bulletin of the Korean Chemical Society
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    • v.33 no.10
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    • pp.3391-3396
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    • 2012
  • Two-dimensional infrared (2D-IR) spectroscopy can probe the fast structural evolution of molecules under thermal equilibrium. Vibrational frequency fluctuation caused by structural evolution produced the time-dependent line shape change in 2D-IR spectrum. A variety of methods has been used to connect the evolution of 2D-IR spectrum with Frequency-Frequency Correlation Function (FFCF), which connects the experimental observables to a molecular level description. Here, a new method to extract FFCF from 2D-IR spectra is described. The experimental observable is the time-dependent frequency shift of maximum peak position in the slice spectrum of 2D-IR, which is taken along the excitation frequency axis. The direct relation between the 2D-IR peak shift and FFCF is proved analytically. Observing the 2D-IR peak shift does not need the full 2D-IR spectrum which covers 0-1 and 1-2 bands. Thus data collection time to determine FFCF can be reduced significantly, which helps the detection of transient species.

A Study on the X-ray Diffraction of the Muscle by the Electrical Stimulation (근육의 전기자극에 의한 X선 회절 분석연구)

  • 김덕술;송주영
    • Journal of Life Science
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    • v.8 no.4
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    • pp.373-380
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    • 1998
  • A considerable change observed in X-ray diffraction during the muscle contraction was that the movement of myosin head and conformational change of contractile monecules were occurred in the muscle contraction. Time slice requires tension peak after the onset of stimulation and the height of tension peak depends on the number of twitch cycle. The intensity of I$_{11}$, I$_{10}$, 143${\AA}$ reflection is measured with 5ms time resolution and is recorded in isometric tension. The peak height of I$_{11}$ and 143${\AA}$ intensity is changed after the onset of a stimulation I$_{i}$, and the length of twitch is shortened by successive twitches in the case of stimulation TI$_{i}$. On the other hand, the peak height of I$_{11}$ and 215${\AA}$ intensity starts to decrease at the 1st twitch and remains constant at low peak hight without appreciable recovery during the contraction term. In the case of uccessive twitch stimulation, the myosin heads of muscle are once moved from their resting position and never returned to their initial position.

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Application-Adaptive Performance Improvement in Mobile Systems by Using Persistent Memory

  • Bahn, Hyokyung
    • International journal of advanced smart convergence
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    • v.8 no.1
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    • pp.9-17
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    • 2019
  • In this article, we present a performance enhancement scheme for mobile applications by adopting persistent memory. The proposed scheme supports the deadline guarantee of real-time applications like a video player, and also provides reasonable performances for non-real-time applications. To do so, we analyze the program execution path of mobile software platforms and find two sources of unpredictable time delays that make the deadline-guarantee of real-time applications difficult. The first is the irregular activation of garbage collection in flash storage and the second is the blocking and time-slice based scheduling used in mobile platforms. We resolve these two issues by adopting high performance persistent memory as the storage of real-time applications. By maintaining real-time applications and their data in persistent memory, I/O latency can become predictable because persistent memory does not need garbage collection. Also, we present a new scheduler that exclusively allocates a processor core to a real-time application. Although processor cycles can be wasted while a real-time application performs I/O, we depict that the processor utilization is not degraded significantly due to the acceleration of I/O by adopting persistent memory. Simulation experiments show that the proposed scheme improves the deadline misses of real-time applications by 90% in comparison with the legacy I/O scheme used in mobile systems.

Prediction of Time Histories of Seismic Ground Motion using Genetic Programming

  • YOSHIHARA, Ikuo;Inaba, Masaaki;AOYAMA, Tomoo;Yasunaga, Moritoshi
    • 제어로봇시스템학회:학술대회논문집
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    • 1999.10a
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    • pp.226-229
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    • 1999
  • We have been developing a method to build models for time series using Genetic Programming. The proposed method has been applied to various kinds of time series e.g. computer-generated chaos, natural phenomena, and financial market indices etc. Now we apply the prediction method to time histories of seismic ground motion i.e. one-step-ahead prediction of seismographic amplitude. Waves of earthquakes are composed of P-waves and S-waves. They propagate in different speeds and have different characteristics. It is believed that P-waves arrive firstly and S-waves arrive secondly. Simulations were performed based on real data of Hyuganada earthquake which broke out at southern part of Kyushuu Island in Japan. To our surprise, prediction model built using the earthquake waves in early time can enough precisely predict main huge waves in later time. Lots of experiments lead us to conclude that every slice of data involves P-wave and S-wave. The simulation results suggest the GP-based prediction method can be utilized in alarm systems or dispatch systems in an emergency.

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Process -dynamic Model for Stock-fluid in a Pressurized Paper Machine Headbox (초지기 가압-헤드박스 내 지료유체의 공정-동특성모델)

  • 윤성훈
    • Journal of Korea Technical Association of The Pulp and Paper Industry
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    • v.31 no.3
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    • pp.35-46
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    • 1999
  • Mathematical modeling provided a systematic analysis for the dynamic behavior of stock fluid in a paper machine pressurized headbox. Dynamic responses of liquid level, sheet basis weight and hydraulic pressure were predicted from the simulation model which represents the system. A unit step and asinusoidal wave load were considered as the input forcing functions in the headbox. Results are summarized as follows : 1. The dependence of sheet basis weight on liquid level in the pressurized-headbox was non -linear. 2. Liquid level in the head-box showed first-order lag with a unit step forcing to fluid input rate ; 3 . The amplitude of wave response of liquid level was inversely proportional to the time content for the sinusoidal input changes ; 4.Sheet basis weight showed second-order oscillating underamped responses for the step input load of flow rate ; 5. The damping factor in the second-order system was a function of air-pressure in the headbox ; and, 6. Dead-time existed in the measuring process for the headbox slice pressure.

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The Design of Expanded Time Slice Task Scheduling in $\mu$ C/OS-II ($\mu$ C/OS-II에서의 확장된 시분할 스케줄링 설계)

  • 김태호;김창수;박철동;장용호
    • Proceedings of the Korea Multimedia Society Conference
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    • 2001.06a
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    • pp.8-11
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    • 2001
  • 다수의 RTOS(Real-Time Operating Systems)가 개발되면서 다양한 분야에서 적용되고 있다. 현재 RTOS는 가전제품과 같은 특정 목적의 장치들을 지원하기 위해 설계되어 있기 때문에 목적에 따라 설계 방향이 다양하게 개발되어 있다. 본 논문에서는 $\mu$ C/OS-II 대전 2.03 환경에서 동일한 우선 순위를 가진 여러 개의 태스크들을 관리하는 방법과 우선 순위에 기반한 선점 메커니즘을 지원하는 $\mu$ C/OS-II에서 동일 우선 순위를 가진 태스크들을 동작하도록 하는 기능을 추가하였다. 이를 위해 본 연구에서는 $\mu$ C/OS-II의 커널 구조를 변경하여 시뮬레이션을 수행하였다.

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Pre- and Post Processing System on Prediction Analysis of Thermal Stress in Mass Concrete Structure (매스콘크리트의 온도균열 예측해석에서의 전후처리 시스템 개발에 관한 연구)

  • 김유석;강석화;박칠림
    • Proceedings of the Korea Concrete Institute Conference
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    • 1996.04a
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    • pp.270-274
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    • 1996
  • Until recently pre & post-processing of finite element model has been heavily relied on expensive graphic peripheral devices. But today, with the aid of inexpensive microcomputers, very effective pre & postprocessor graphics has been developed. In this study, Pre & Post processor(MASSPRE, MASSPOST) of prediction analysis of thermal stress in mass concrete structure is developed. The developed pre & post processors are raise to the efficiency in making input data for the main program and analysis of the results produced by the main program. This MASSPOST presents a stress contour graph, volume slice, time-temperature history graph, time-stress history graph, etc.

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Query System for Analysis of Medical Tomography Images (의료 단층 영상의 분석을 위한 쿼리 시스템)

  • Kim, Tae-Woo;Cho, Tae-Kyung;Park, Byoung-Soo
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.5 no.1
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    • pp.38-43
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    • 2004
  • We designed and implemented a medical image query system, including a relational database and DBMS (database management system), which can visualize image data and can achieve spatial, attribute, and mixed queries. Image data used in querying can be visualized in slice, MPR(multi-planner reformat), volume rendering, and overlapping on the query system. To reduce spatial cost and processing time in the system. brain images are spatially clustered, by an adaptive Hilbert curve filling, encoded, and stored to its database without loss for spatial query. Because the query is often applied to small image regions of interest(ROI's), the technique provides higher compression rate and less processing time in the cases.

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