• Investigative Magnetic Resonance Imaging
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• v.3 no.2
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• pp.173-178
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• 1999

Purpose : To evaluate the usefulness of functional MRI (fMRI) of visual cortex in patients with ischemic infarction in the occipital lobe. Materials and Methods : Four patients with the symptoms and signs of visual cortical ischemia were included. Functional MRI was performed by 2D-FLASH technique with the parameter of 90/56msec TR/TE, $40^{\circ}$ flip angle, $240{\times}240{\;}FOV,{\;}64{\times}128$ matrix number, 8.32 seconds acquisition time, 8mm slice thickness. An axial slice including both visual cortices was selected and alternative activation and resting of the visual cortex was performed using red color photostimulator. all patients undertook visual field test, and vascular abnormality was examined by MRA (n=4) and DSA (n=2). fMRI results were compared with the results of a visual field test, conventional MRI and cerebral angiography. Results : On fMRI, decreased activity of the visual cortex was found in the occipital lobe corresponding to stenosis of the posterior cerebral artery or its branch noted on angiogram. However, 2 of 4 patients showed no abnormal findings on conventional MRI. Visual field defect was noted in 3 patients, one and of whom showed no abnormality on conventional MRI and diffusion-weighted image, but revealed decreased activity in the corresponding visual cortex on fMRI. Conclusion : fMRI may be a sensitive method for detection of the status of decreased blood flow or vascular reserve which other methods can not.

• Clinical and Experimental Pediatrics
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• v.51 no.10
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• pp.1112-1117
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• 2008

Purpose : We intended to observe cell death and apoptotic changes in neurons in organotypic hippocampal slice cultures following oxygen-glucose deprivation (OGD), using propidium iodide (PI) uptake, Fluoro-Jade (FJ) staining, TUNEL staining and immunofluorescent staining for caspase-3. Methods : The hippocampus of 7-day-old rats was cut into $350{\mu}m$ slices. The slices were cultured for 10 d (date in vitro, DIV 10) and and exposed to OGD for 60 min at DIV 10. They were then incubated for reperfusion under normoxic conditions for an additional 48 h. Fluorescence of PI uptake was observed at predetermined intervals, and the cell death percentage was recorded. At 24 h following OGD, the slices were Cryo-cut into $15{\mu}m$ thicknesses, and Fluoro-Jade staining, TUNEL staining, and immunofluorescence staining for caspase-3 were performed. Results : 1) PI uptake was restricted to the pyramidal cell layer and DG in the slices after OGD. The fluorescent intensities of PI increased from 6 to 48 h during the reperfusion stage. The cell death percentage significantly increased time-dependently in CA1 and DG following OGD (P<0.05). 2) At 24 h after OGD, many FJ positive cells were detected in CA1 and DG. Some neurons had distinct nuclei and processes while others had fragmented nuclei and disrupted processes in CA1. TUNEL and immunofluorescent staining for caspase-3 showed increased expression of TUNEL labeling and caspase-3 in CA1 and DG at 24 h after OGD. Conclusion : The numerous dead cells in the slice cultures after OGD tended to display apoptotic changes mediated by the activation of caspase-3.

• The Korean Journal of Physiology
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• v.7 no.2
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• pp.9-16
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• 1973

In view of the recent knowledge on the radioprotective action of reduced glutathione (GSH), the present study was designed the elucidate the effect of some concentrations of GSH on the levels of intrinsic non-protein sulfhydryl (NP-SH) and non-protein disulfide (NP-SS) of the mouse liver incubated at 4, 25 and 37C in vitro, respectively. The liver slice of the mouse was incubated at 4, 25 and 37C in the medium composed of 100 ml of Krebs-Ringer phosphate buffer (KRP) with the addition of 10, 20 and 30 mg of GSH, respectively. Measurement of NP-SH and NP-SS was made at 5, 30 and 60 min during the course of the incubation, and the results were compared with the controls which were incubated only in KRP medium, and the normal. The results thus obtained are summarized as follows: 1. When the mouse liver slice was incubated at 4C, the values of both NP-SH and NP-SS of the control and the group where 10 mg of GSH was added to the incubation medium were similar to those of the normal group, and the increase of NP-SH and NP-SS with the increased concentrations of GSH was not prominent. 2. When the liver slice was incubated in the concentrations of GSH 20 mg/100 ml KRP and GSH 30 mg/100 ml KRP at 25 C, the rate of increase of both NP-SH and NP-SS was proportional to the increase of GSH concentration. In the group where 10 mg of GSH was added to the incubation medium, the value of NP-SH and NP-SS reached the highest value at 30 min, but a tendency of decrease was observed at 60 min. 3. The rate of increase of NP-SH and NP-SS of the liver was most marked of all the group. studied when the incubation temperatuse was elevated to 37C, and the increase was proportional to the concentration of GSH and the incubation time.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.17 no.2
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• pp.397-404
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• 2013

This paper propose the hardware architecture of face detection hardware system using the AdaBoost algorithm. The proposed structure of face detection hardware system is possible to work in 30frame per second and in real time. And the AdaBoost algorithm is adopted to learn and generate the characteristics of the face data by Matlab, and finally detected the face using this data. This paper describes the face detection hardware structure composed of image scaler, integral image extraction, face comparing, memory interface, data grouper and detected result display. The proposed circuit is so designed to process one point in one cycle that the prosed design can process full HD($1920{\times}1080$) image at 70MHz, which is approximate $2316087{\times}30$ cycle. Furthermore, This paper use the reducing the word length by Overflow to reduce memory size. and the proposed structure for face detection has been designed using Verilog HDL and modified in Mentor Graphics Modelsim. The proposed structure has been work on 45MHz operating frequency and use 74,757 LUT in FPGA Xilinx Virtex-5 XC5LX330.

• The KIPS Transactions:PartA
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• v.14A no.5
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• pp.301-308
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• 2007

This paper proposes high performance coprocessor architecture for real time dense disparity computation based on a phase-based binocular stereo matching technique called local weighted phase-correlation(LWPC). The algorithm combines the robustness of wavelet based phase difference methods and the basic control strategy of phase correlation methods, which consists of 4 stages. For parallel and efficient hardware implementation, the proposed architecture employs SIMD(Single Instruction Multiple Data Stream) architecture for each functional stage and all stages work on pipelined mode. Such that the newly devised pipelined linear array processor is optimized for the case of row-column image processing eliminating the need for transposed memory while preserving generality and high throughput. The proposed architecture is implemented with Xilinx HDL tool and the required hardware resources are calculated in terms of look up tables, flip flops, slices, and the amount of memory. The result shows the possibility that the proposed architecture can be integrated into one chip while maintaining the processing speed at video rate.

• Journal of KIISE:Databases
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• v.29 no.1
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• pp.15-26
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• 2002

Most work on multimedia storage systems has assumed that client will be serviced using a round-robin strategy. The server services the clients in rounds and each client is allocated a time slice within that round. Furthermore, most such algorithms are evaluated on the basis of a tightly coupled cost function. This is the basis of well-known algorithm such as FCFS, SCAN, SCAN-EDF, etc. In this paper, we describe a scheduling module called Request Unifier(RU) that takes as input, a set of client request, and a set of constraints on the desired performance such as client waiting time or maximum disk bandwidth, and a cost function. It produces as output a Unified Read Request(URR), telling the storage server which data items to read and when these data items to be delivered to the clients. Given a cost function, a URR is optimal if there is no other URR satisfying the constraints with a lower cost. We present three algorithms in this paper that can accomplish this kind of request merging and compare their performance through an experimental evaluation.

• Journal of the Korean Society of Radiology
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• v.13 no.7
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• pp.941-946
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• 2019

Computed tomography (CT) has been increasing in frequency and indications for use in clinical diagnosis and treatment decisions. Multidetector CT has the advantage of shortening the inspection time and obtaining a high resolution image compared to a single detector CT, but has been pointed out the disadvantage of increasing the radiation exposure. In addition, when the low tube voltage is used to reduce the exposure dose in the CT, noise increases relatively. In the existing method, the method of finding the optimal image quality using the method of adjusting the parameters of the image reconstruction method is not a fundamental measure. In this study, we applied a double-tree complex wavelet algorithm and analyzed the results to maintain the normal signal and remove only noise. Experimental results show that the noise is reduced from 8.53 to 4.51 when using a complex oriented 2D method with 100kVp and 0.5sec rotation time. Through this study, it was possible to remove the noise and reduce the patient dose by using the optimal noise reduction algorithm. The results of this study can be used to reduce the exposure of patients due to the low dose of CT.

• Proceedings of the KSMRM Conference
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• 2001.11a
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• pp.111-111
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• 2001

목적： To evaluate the feasibility of the event-related functional MR study using power grip studying the hand motor system 대상 및 방법： Event-related functional MRI was performed on a 1.5T MR unit in seven norm volunteers (man=7, right-handedness=2, left-handedness=5, mean age： 25 years). A single-shot GRE-EPI sequence (TR/TE/flip angle： 1000ms/40ms/90, FOV = 240 mm matrix= 64$\times$64, slice thickness/gap = 5mm/0mm, 7 true axial slices) was used for functiona MR images. A flow-sensitive conventional gradient echo sequence (TR/TE/flip angl 50ms/4ms/60) was used for high-resolution anatomical images. To minimize the gross hea motion, neck-holders (MJ-200, USA) were used. A series of MR images were obtained in axial planes covering motor areas. To exclude motion-corrupted images, all MR images wer surveyed in a movie procedure and evaluated using the estimation of center of mass of ima signal intensities. Power grip task consisted of the powerful grip of all right fingers and hand movement ta used very fast right finger tapping at a speed of 3 per 1 second. All tasks were visual-guid by LCD projector (SHARP, Japan). Two tasks consisted of 134 phases including 7 activatio and 8 rest periods. Active stimulations were performed during 2 seconds and rest period were 15 seconds and total scan time per one task was 2 min 14 sec. Statistical maps we obtained using cross-correlation method. Reference vector was time-shifted by 4 seconds an Gaussian convolution with a FWHM of 4 seconds was applied to it. The threshold in p val for the activation sites was set to be 0.001. All mapping procedures were peformed usin homemade program an IDL (Research Systems Inc., USA) platform. We evaluated the activation patterns of the motor system of power grip compared to hand movement in t event-related functional MRI.

• Journal of radiological science and technology
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• v.38 no.2
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• pp.121-126
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• 2015

To image diagnosis in neurovascular diseases using Multi-Detector Computed Tomography(MDCT), injected the same contrast material when inspecting Brain Computed Tomography Angiography(BCTA) to examine radiation dose and Image quality on changing Cerebral Artery CT number by tube voltage. Executed an examination with same condition[Beam Collimation $128{\times}0.6mm$, Pitch 0.6, Rotation Time 0.5s, Slice Thickness 5.0mm, Increment 5.0mm, Delay Time 3.0sec, Care Dose 4D(Demension ; D)] except for tube voltage on 50 call patients for BCTA and divided them into two groups (25 people for a group, group A: 80, group B: 120kVp). From all the acquired images, set a ROI(Region of Interest) on four spots such as left cerebral artery, right cerebral artery, posterior cerebral artery and cerebral parenchyma to compare quantitative evaluation, qualitative evaluation and effective dose after measuring CT number value from Picture Archiving Communications System(PACS). Evaluating images with CT number acquired from BCTA examination, images with 80 kVp was 18% higher in Signal to Noise Ratio and 19% in Contrast to Noise Ratio than those with 120 kVp. It was seen that expose dose was decreased by over 50% with tube voltage 80 kVp than with 120 kVp. Group A (25 patients) was examination with tube voltage 80kVp while group B with 120 kVp to examine radiation dose and Image quality. It is considered effective to inspect with lower tube voltage than with conventional high kVp, which can reduce radiation dose without any affect on diagnosis.

• Journal of the Institute of Electronics Engineers of Korea SP
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• v.49 no.2
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• pp.28-34
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• 2012

Various feature extraction algorithms are widely applied to real-time image processing applications for extracting significant features from images. Feature extraction algorithms are mostly combined with image processing algorithms mostly for image tracking and recognition. Feature extraction function is used to supply feature information to the other image processing algorithms and it is mainly implemented in a preprocessing stage. Nowadays, image processing applications are faced with embedded system implementation for a real-time processing. In order to satisfy this requirement, it is necessary to reduce execution time so as to improve the performance. Reducing the time for executing a feature extraction function dose not only extend the execution time for the other image processing algorithms, but it also helps satisfy a real-time requirement. This paper explains FAST (Feature from Accelerated Segment Test algorithm) of E. Rosten and presents FPGA-based embedded hardware accelerator architecture. The proposed acceleration scheme can be implemented by using approximately 2,217 Flip Flops, 5,034 LUTs, 2,833 Slices, and 18 Block RAMs in the Xilinx Vertex IV FPGA. In the Modelsim - based simulation result, the proposed hardware accelerator takes 3.06 ms to extract 954 features from a image with $640{\times}480$ pixels and this result shows the cost effectiveness of the propose scheme.