• Title/Summary/Keyword: Time of onset

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Analysis of Endotoxin Using Analytical Conditions of Optical Density in Metalworking Fluid Sample (금속가공유 시료에서 일부 Optical Density 설정값에 따른 엔도톡신의 정량)

  • Park, Dong-Uk;Han, In-Young;Yoon, Chung-Sik;Park, Doo-Yong
    • Analytical Science and Technology
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    • v.15 no.5
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    • pp.459-465
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    • 2002
  • This study was performed to identify the proper analytical conditions of endotoxins regarding optical density in the workplace where metalworking fluids are used. This study found that "onset time method" was more accurate than "time to $V_{max}$ method". Reproducibility and accuracy analyzed by "onset time method" was greatly higher than the "time to $V_{max}$". The optical density of "0.03" was the most appropriate analytical condition among "onset time method". In this analytical condition, linearity of 0.998 was obtained and recovery rate ranged from 88% to 105% at the endotoxin concentrations below 5 EU/mL. No significant difference of endotoxins was observed between the optical densities of "0.03" and "0.05". However, correlation coefficients were different with statistical significance (p<0.01). This study confirmed that either the optical densities "0.03" or "0.05" should be used to analyze endotoxin. Of these optical density values, OD with correlation coefficient higher than 0.98 should be used to analyze endotoxin in environmental samples.

Relationship between Juvenile Delinquency, Sensation Seeking, and Impulsivity: Focusing on Delinquency-Onset Type (청소년 비행과 감각추구성, 충동성 간의 관련성: 비행 시발 시기를 중심으로)

  • Yoon, Eon Jung;Kim, Kyong Yeon
    • Human Ecology Research
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    • v.52 no.6
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    • pp.639-649
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    • 2014
  • The main purpose of this study was to find the relationship between the delinquency-onset time in the source and the continuity of delinquency. In order to achieve this objective, we divided 350 first-year high school students into three groups early-onset type, late-onset type, and non-delinquent adolescents on the basis of the delinquency onset. The results of this study were as follow: (1) for the boys, the early-onset type shows a higher continuity of delinquency than both the late-onset type and the general adolescents. On the other hand, for the girls, the early-onset type shows a higher continuity of delinquency than the late-onset type, but there was no difference in the persistence duration between the late-onset type and the non-delinquent adolescents. (2) For the boys, the examination reveals that the early-onset type has a higher degree of sensation seeking and impulsivity than the general adolescents. In addition, the early-onset type shows a higher degree of sensation seeking than the late-onset type, whereas the two show no difference in impulsivity. For the girls, sensation seeking did not show any difference depending on the delinquency onset. However, more impulsivity appeared in the early-onset type than in the late-onset type or the non-delinquent adolescents. (3) The relative priorities of variables determining the group to which the students belong on the basis of the delinquency onset are in the order of sensation seeking and juvenile impulsivity. Therefore, this study, suggests that the early-onset type requires a different kind of intervention than the late-onset type.

The Effects of Seat Surface Inclination on the Onset of Muscle Contraction during Sit-to-stand in Healthy Adults

  • Shin, Hwa-Kyung;Ryu, Young-Uk
    • The Journal of Korean Physical Therapy
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    • v.24 no.6
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    • pp.383-387
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    • 2012
  • Purpose: Rising from a chair is important for activities of daily living. Several factors have influence on sit-to-stand movement. We studied the effect of inclination of seat surface of on the movement of rising from a chair with electromyographic (EMG). Methods: Twelve subjects performed the sit-to-stand movement on anterior-inclined, standard, and posterior inclined chair. We measured onset time of tibialis anterior and rectus femoris with EMG on each inclination chair. Results: The onset time at the anterior-inclined chair is significantly faster than it at the standard chair (p<0.05). And the onset time at the posterior-inclined chair is significantly slower than it at the standard chair (p<0.05). Conclusion: Rising from anterior inclined chair appeared to be more effective than rising from the standard and posterior inclined chair. Therefore, this finding suggests that the selection of set surface inclination must be considered for activities of daily living during rehabilitation.

Effects of Hwangryunagyo-tang on Sleep Onset and Total Duration of Sleep Induced by Thiopental Dodium in Mice (Thiopental sodium으로 유도된 수면에서 황련아교탕의 입면 및 수면지속 효과)

  • Leem, Kanghyun;Kim, Taeyeon
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.36 no.1
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    • pp.7-10
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    • 2022
  • Hwangryunagyo-tang (HT) is a herbal cocktail to treat insomnia induced by yin deficiency with effulgent fire. In the present study, the onset time and the duration time of sleep were measured 30 minutes after thiopental sodium injection. And c-fos immunohistochemistry was performed to find the activated nerve cells of the ventrolateral preoptic nucleus (VLPO) and tuberomammillary nucleus (TMN) sites in the brain. HT significantly increased the number of activated nerve cells in the sleep-inducing center (VLPO), whereas HT significantly decreased the number of activated nerve cells in the arousal center (TMN). It could be concluded that the HT shortened the onset time and increased the duration time for sleep induced by thiopental sodium. And it was confirmed that the mechanism acted by activating the sleep-inducing center (VLPO) and suppressing the arousal center (TMN) in the brain. The results are considered to be useful as scientific evidence HT can be used clinically for the treatment of insomnia caused by yin deficiency with effulgent fire.

COMPARISON OF DEMOGRAPHIC, CLINICAL, PSYCHOLOGICAL CHARACTERISTICS BETWEEN CHILDHOOD AND ADOLESCENT-ONSET SCHIZOPHRENIA (소아기 발병 및 청소년기 발병 정신분열병 환아의 인구학적, 임상적, 심리학적인 특성)

  • Chungh Dong-Seon;Lim Myung-Ho;Kim Soo-Kyoung;Jung Gwang-Mo;Hwang Jun-Won;Kim Boong-Nyun;Shin Min Sup;Cho Soo-Churl;Hong Kang-E
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.16 no.2
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    • pp.219-230
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    • 2005
  • Objectives : This study was designed to compare the demographic data, clinical characteristics, developmental delay, and psychological tests between childhood-onset and adolescent-onset schizophrenic in-patients. Methods Medical records of the 17 childhood-onset (very early onset) Schizophrenia and 16 adolescent-onset (early onset) Schizophrenia in-patients were reviewed. Sex, age, psychiatric past history, prodromal symptoms and period, subtype, co-morbid disease, developmental delay, prescribed drug and dosage, treatment response, intelligence quotient (IQ), and Rorschach test were evaluated. Results : The mean admission age of childhood-onset (very early onset) group and adolescent-onset (early onset) group were 12.69$({\pm}2.34)$ and 15.13$({\pm}1.04)$ years. The mean onset age of childhood-onset(very early onset) group and adolescent-onset (early onset) group were 10.79$({\pm}1.95)$ and 14.46$({\pm}0.82)$ years. The mean prodromal period of childhood-onset (very early onset) group and adolescent-onset (early onset) group were 15.94$({\pm}12.33)$ and 8.06$({\pm}6.10)$ month. The time to remission period of childhood-onset (very early onset) group and adolescent-onset (early onset) group were 50.58$({\pm}24.67)$ and 30.06$({\pm}18.04)$ days. Longer time to remission period in childhood-osnet (very early onset) group was associated with earlier age of onset. The mean of total IQ, performance IQ, verbal IQ were at an average level. Discussion : Childhood-onset (very early onset) group and adolescent-onset (early onset) group Schizophrenia had different clinical and psychological features including prodromal period, and IQ subtests.

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The Effect of Knee Exercises on the Onset Time of Vastus Medialis Oblique and Vastus Lateralis Muscle (무릎운동훈련들이 안쪽빗넓은근과 가쪽넓은근의 수축 개시시간에 미치는 효과)

  • Kim, Myoung-Jin;Kim, Ji-Won;Lee, Jae-On;Park, Kyoung-Hee;Shin, Hwa-Kyoung
    • Physical Therapy Korea
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    • v.8 no.2
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    • pp.65-72
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    • 2001
  • The purpose of this study was to investigate the effect of knee exercises on the onset times of vastus medialis oblique muscle (VMO) and vastus lateralis muscle (VL) and in healthy subjects. Fifteen subjects (7 men, 8 women) in a mean age of 26.4 years participated in the study. Electromyographic (EMG) signals were recorded from the VMO and VL under four exercises. Knee exercises consisted of open kinematic terminal knee extension, straight leg raising, isometric hip adduction exercise, and closed kinematic terminal knee extension. No significant differences were found in the onset times of EMG activities of VMO and VL in the four exercises. There were also no significant differences among the exercises. These results coincided with previous studies that found no difference between onset of VMO and VL. However, it is difficult to say that there is no difference between onset of VMO and VL in healthy subjects. To confirm this results, further researches that follow same on set determination metod and exercises are needed. Not only is the study of onset time of muscle needed, but also the studies of the amount of activation and the rate of increase of muscle activation are needed.

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The Analysis on Pre-hospital Cases of Cardiac Arrest and Drug Intoxication during Local Emergency Activities - Based on Differences between Elderly Group and Non-Elderly Group - (일개지역 구급활동 중 병원 전 심정지 및 약물중독 환자 분석 - 노인대 비노인의 차이를 중심으로 -)

  • Lee, Jae-Min;Yun, Hyeong-Wan
    • The Korean Journal of Emergency Medical Services
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    • v.14 no.3
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    • pp.83-93
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    • 2010
  • Purpose: The purpose of this study is to determine potential differences in pre-hospital cases of cardiac arrest and drug Intoxication between elderly group and non-elderly group on local emergency activity sites of rescue 119 team for those cases, so that it can provide useful reference materials for a system of corresponding emergency medical services. Methods: Patients with cardiac arrest and drug intoxication in the elderly and the non-elderly group were analyzed by analyzing the Ambulance Run Report for 3 years from January 2007 to December 2009. Results: According to analysis on potential differences between elderly and the non-elderly group, it was found that there was no significant difference between elderly cases (evacuated to hospital due to cardiac arrest and drug poisoning) and non-elderly cases in year of onset (p = .247), quarter of onset (p = .813), sex (p = .235), consciousness state (p = .126), place of onset (p = .215) and number of first aid services (applied to emergency cases) respectively, but there were significant differences between elderly cases and non-elderly cases in guardian availability (p = .042), time zone of onset (p = .050), distance from the site of onset (p = .278), type of onset (p = .000), number of first aid services depending on distance of evacuation (p = .008) and effectiveness of emergency care (p = .003) on statistical basis. Conclusion: It is important to establish a system of early emergency case reports for rational emergency case management with lower mortality; shorten distance from the site of onset at each time zone of onset in emergency cases; employ more emergency team members; facilitate firsthand / secondhand medical instructions for emergency teams in specialized emergency care depending on distance of evacuation for each kind of onset (elderly group vs. non-elderly group); and improve rate of resuscitated emergency cases by extending the scope of works for emergency medical technicians into wider applications, so that it will be possible to take timely and appropriate measures for emergency settings of ever-increasing aged population in near future.

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Detection of Onset and Offset Time of Muscle Activity in Surface EMG using the Kalman Smoother

  • Lee Jung-Hoon;Lee Hyun-Sook;Lee Young-Hee;Yoon Young-Ro
    • Journal of Biomedical Engineering Research
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    • v.27 no.3
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    • pp.131-141
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    • 2006
  • A visual decision by clinical experts like physical therapists is a best way to detect onset and offset time of muscle activation. The current computer-based algorithms are being researched toward similar results of clinical experts. The new algorithm in this paper has an ability to extract a trend from noisy input data. Kalman smoother is used to recognize the trend to be revealed from disorderly signals. Histogram of smoothed signals by Kalman smoother has a clear boundary to separate muscle contractions from relaxations. To verify that the Kalman smoother algorithm is reliable way to detect onset and offset time of muscle contractions, the algorithm of Robert P. Di Fabio (published in 1987) is compared with Kalman smoother. For 31 templates of subjects, an average and a standard deviation are compared. The average of errors between Di Fabio's algorithm and experts is 109 milliseconds in onset detection and 142 milliseconds in offset detection. But the average between Kalman smoother and experts is 90 and 137 milliseconds in each case. Moreover, the standard deviations of errors are 133 (onset) and 210 (offset) milliseconds in Di Fabio's one, but 48 (onset) and 55 (offset) milliseconds in Kalman smoother. As a result, the Kalman smoother is much closer to determinations of clinical experts and more reliable than Di Fabio's one.

Reliability of the Onset Time Determinations During Maximal Isometric Contraction in Surface EMG (최대 등척성 수축시 표면근전도에서 근 수축 개시점 결정을 위한 기법들의 신뢰도)

  • Chung, Yi-Jung;Cho, Sang-Hyun;Lee, Jung-Hoon;Lee, Sang-Heon
    • Physical Therapy Korea
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    • v.10 no.1
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    • pp.51-62
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    • 2003
  • The purpose of this study was to compare the relative accuracy of a range of computer-based analysis with respect to EMG onset determined visually by an experienced examiner. Ten healthy students (6 male, 4 female) were recruited and three times randomly selected trials of isometric contraction of wrist flexion and extension were evaluated using four technique. These methods were compared which varied in terms of EMG processing, threshold value and the number of samples for which the mean must exceed the defined threshold, and beyond 7% of maximum amplitude. To identify determination of onset time, ICCs(Intraclass Correlation Coefficients) was used and inter-rater arid intra-rater reliability ranged good in visually derived onset values. The results of this study present that in wrist flexion and extension, the reliability of the inter and intra-examiner muscle contraction onset times through visual analysis showed beyond .971 with ICCs. The reliability of the muscle contraction onset time decision through visual reading, tested with computer analysis, showed a relationship of all the selected analysis methods with ICCs .859 and .871. The objective computer-based analysis comparing with visual reading at the same time is the effective and qualitative data analysis method, considering the specificity of each study method.

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Comparisons of Vastus Medialis and Vastus Lateralis EMG Onset Time During Quadriceps Strengthening Exercise in Neutral and Adducted Hip Positions (대퇴사두근 근력 운동 시 고관절 중립 자세와 내전 자세에 따른 내측광근과 외측광근의 근수축 개시 시간 차이 비교)

  • Choi, Bo-Ram;Kim, Min-Heem;Jeon, Hye-Seon
    • Physical Therapy Korea
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    • v.16 no.3
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    • pp.42-49
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    • 2009
  • This study examined the vastus medialis oblique (VMO) and the vastus lateralis (VL) onset time differences (OTD) during quadriceps contraction in different hip positions. Twelve healthy subjects were recruited (four men, eight women). Surface EMG activities of the VMO and VL were measured during a quadriceps strengthening exercise in a long sitting condition and in a sitting at a chair with feet hanging condition. For each condition, subjects were tested in two hip positions (neutral and adduction). The OTD between the two muscles was calculated for each condition, by subtracting the onset time of the VL from the VMO. Therefore, the negative value of OTD represent earlier EMG onset of the VMO compared to the VL. The OTD was not significantly different between the hip neutral and the hip adduction position in the long sitting condition (p=.064). However, the OTD was significantly different between the hip neutral position ($15.83{\pm}109.51$ ms) and hip adduction position ($-5.58{\pm}121.08$ ms) during the sitting at a chair with feet hanging condition (p=.047). The negative OTD value in the hip adduction condition during quadriceps strengthening exercises is the result of earlier onset of the VMO than VL. Therefore, quadriceps contraction in the hip adduction position can prevent the risk of patella lateral tracking. We expect that quadriceps strengthening exercise in the hip adduction position will be a safe way to prevent patellofemoral pain syndrome resulting from abnormal patella lateral tracking.

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