• Radiation Oncology Journal
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• 제11권1호
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• pp.91-96
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• 1993

From September 1989 to June 1992,22 patients with nasopharyngeal carcinoma were treated in Asan Medical Center with an external beam of 60 Gy followed by a boost dose of 15 Gy HDR brachytherapy. There were 5 females and 17 males with median age of 44 years (range: 20-69 years). All patients were histologically confirmed and staged by physical examination, CT scan and/or MRI. By the AJCC TNM staging system, there were 2 patients with stge II (T2NO), 4 with stage III (T3NO, T1-3N1), and 16 with stage IV (T4 or N2-3). Four patients received chemotherapy with 5-FU and cisplatin prior to radiotherapy. All patients were followed up periodically by a telescopic examination and radiologic imaging study of CT scan or MRI with a median follow-up time of 13 months (range: 3-34 months). Twenty one patients showed a complete response ore month after completing therapy and one patient showed a complete response after three months. At the time of this analysis, seventeen patients remain alive without evidence of disease, but four patients developed distant metastasis and one patient died a month after treatment. The local control rate was $100{\%}$ in a median follow-up time of 13 months. The two year overall and disease free survival rates by the Kaplan-Meier method were $94{\%}$ and $67{\%}$, respectively. Serious radiation sequelae have not been observed yet. Although longer follow-up is needed, this retrospective analysis suggests that HDR brachytherap. given as a boost therapy for nasoharyngeal carcinoma may improve the local control. To reduce the incidence of distant metastasis, we need to develop a more effective systemic chemotherapy.

• Journal of Magnetics
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• 제17권2호
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• pp.158-162
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• 2012

Although 3.0T magnetic resonance imaging (MRI) has the advantages of a higher signal to noise ratio (SNR) and contrast than 1.5T MRI, there are limitations on the contrast between white and grey matter because of the long T1 recovery time when T1 images are obtained using the Spin Echo Technique. To overcome this, T1 weighted images are obtained occasionally using the inversion recovery (IR) technique, which employs a relatively long TR. The aim of this study was to determine the optimal TI in a brain examination when a T1 weighted image is obtained using the IR technique. Eight participants (male: 7, female: 1, average age: $34{\pm}14.11$) with a normal diagnosis were targeted from February 18, 2012 to February 27, 2012, and the contrast between white and grey matter as well as the contrast to noise ratio (CNRs) in each participant were measured. The CNRs of white matter and grey matter were highest at TI = 600, 650, 750, 900, 1050 and 1100 ms when the TR was 1100, 1400, 1700, 2000, 2300 and 2600 ms, respectively. Therefore, as the TIs were $44.425{\pm}0.877%$ of the TRs in the TR range of 1400-2300 ms, the optimal T1 weighted images that describe the contrast between white and grey matter can be obtained if the TIs are compensated for with $44.425{\pm}0.877%$ of the TRs in the time of setting TIs.

• 대한영양사협회학술지
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• 제27권4호
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• pp.276-292
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• 2021

There is a dearth of Korean studies on dehydration, one of the health risks for adult women. This study analyzed the subjects of the 2016~2018 National Health and Nutrition Examination Survey (KNHANES) to investigate the relationship between nutrient intake ratios and sedentary time in dehydrated women. Body mass index and waist circumference in the dehydrated group (DG) were significantly higher than the normal group (NG). Intake of other liquids in the DG was significantly higher than in the NG, but total water intake in the DG was significantly lower than in the NG. Compared to the 600 sedentary minutes or more per day group, the odds ratio of dehydration was significantly higher in the less than 300 sedentary minutes per day group (1.871 [95% CI: 1.579~2.215], P<0.001). Compared to the drinking over 6.0 cups of water per day group, the odds ratio of dehydration was significantly higher in the 3 cups or fewer per day (OR [95% CI] is 1.198 times [1.019 to 1.408], P<0.05), and 6.0 cups or fewer group (OR [95% CI] is 1.162 times [1.018 to 1.326], P<0.05). The results of this study showed that the total water intake was relatively lower in the ≥600 sedentary minutes per day group compared to the 300 sedentary minutes per day group, making them more vulnerable to dehydration. The nutrient intake ratios were higher in the dehydration group than in the normal group. In conclusion, emphasis should be placed on the importance of hydration and nutrition education for adult women in the workplace.

• 치위생과학회지
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• 제14권3호
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• pp.332-341
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• 2014

이 연구는 본 학과 졸업생의 학교 성적과 국시 성적을 비교하여 분석하고자 하였다. 즉 본 학과의 6개 연도 졸업생 185명의 학교 성적과 국시 성적의 상관관계를 파악하고, 성별과 졸업 연령 등에 따라 학교 성적과 국시 성적에 차이가 있는지 평가하며, 학교 성적의 여러 세부항목 가운데 국시성적을 가장 적절히 예측할 수 있는 주요 요인이 무엇인지 밝히고자 하였다. 본 학과 졸업생의 학년 평점 및 종합시험 점수는 국시 필기 점수와, 1~3학년의 학년 평점 및 종합시험 점수는 국시총점수와 유의한 양의 상관관계가 있었다. 특히 2학년의 학년 평점이 국시 필기 점수와, 2차 종합시험 점수가 국시 총 점수와 상관성이 가장 높았다. 졸업 총평점이 높거나, 여학생이거나, 졸업 연령이 낮은 졸업생이 국시 필기 점수가 의미 있게 높았으나 국시 실기 점수에는 유의한 차이가 없었다. 2차 종합시험 점수가 국시 총점수와 상관성이 가장 높게 나타난 바, 4학년 2학기에 최종적으로 시행하는 종합시험 점수가 국시 성적을 예측할 수 있는 가장 주된 요인으로 판단된다. 그러나 4년 전체의 졸업 평점이 우수하더라도 국시실기 점수에는 그 영향이 없었으며, 국시 실기와 직접 관련이 있는 4학년의 학년 평점은 오히려 국시 실기 점수와 반대의 양상을 보였다. 또한 국시 실기 점수와 이에 해당하는 학교 교과목 평점도 유의한 상관관계가 없었다. 결론적으로, 학교 성적으로 국시 필기 점수는 신뢰성있게 예측할 수 있으나 국시 필기 점수는 그렇지 못하였다. 이 연구는 일개 학교의 사례라는 한계가 있다. 그러나 학교 교육과 국시가 상치되지 않아야 한다면 치위생학 교육과 치과위생사 국시의 연계성에 관련하여 심층적인 연구가 더욱 활발히 수행되어야 할 것으로 생각된다.

• 핵의학기술
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• 제13권1호
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• pp.40-46
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• 2009

목적 : 분화된 갑상선암 환자에서 방사성옥소(I-131)를 이용한 전신스캔은 보통 수술 후 잔여 갑상선 조직, 재발된 병변 부위 또는 전이 병소 등을 찾는데 유용한 방법이다. 최근 고선량 방사성동위원소를 이용한 치료는 증가 추세에 있으며, 동위원소 치료를 위한 입원대기는 수개월씩 지연되고 있다. 본원에서는 정화조 설비를 확장하여 주당 치료 가능 인원이 증가되었고 이로 인해 I-131 전신스캔 환자가 늘어나면서 검사시간 또한 증가되었다. 이를 개선하기 위해 본 연구에서는 기존의 검사시간을 단축하면서 병소의 위치를 정확하게 구별할 수 있도록 Transmission scan tool을 제작하여 우수한 분해능을 가진 전신영상을 얻고자 한다. 실험재료 및 방법 : 2008년 2월부터 7월까지 본과를 내원하고 ORBITER Gamma Camera를 이용하여 I-131 전신스캔을 시행하는 환자를 대상으로 하였다. 먼저 전신 스캔을 시행한 후 Transmission scan를 위해 검사 Table에 Rail을 설치하고 $^{99m}Tc$-pertechnetate 2 mCi를 희석한 Flood phantom을 올려놓을 수 있는 Tool을 자체 제작하여 Transmission image를 얻어 전신 스캔에 Fusion 하였다. 결과 : I-131 전신스캔과 Transmission scan의 Fusion된 영상은 간단한 marking을 통하여 구강이나 침샘부위, neck 부위의 병소, 전이병소의 위치를 감별하는데 우수한 분해능을 가진다. 또한 추가적인 국소 영상이 불필요하여 8~28분 정도의 검사 소요시간을 단축할 수 있었다. 결론 및 고찰 : I-131 전신스캔에서 Transmission scan은 방사능의 감약을 통하여 체표면의 윤곽을 정확히 나타낼 수 있으며 미리 시행한 I-131 전신스캔과의 Fusion 영상을 통하여 분해능을 향상시킴으로서 잔여 갑상선 조직이나 전이병소 등의 위치를 나타내는데 유용하다. 또한 추가적인 국소영상 촬영이 불필요함에 따라 검사에 소요되는 시간을 단축할 수 있고, 체표면 윤곽을 나타내어 해부학적 위치를 파악하는데 도움을 줄 수 있는 다른 임상검사에도 확대 적용할 수 있을 것이다.

• 한국보육지원학회지
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• 제19권6호
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• pp.21-37
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• 2023

Objective: This study aims to investigate the perception and demand of child care teachers regarding the support project for part-time substitute teachers in Busan. Methods: A survey was conducted on 6,141 childcare teachers participating in the Busan part-time substitute teacher support project, and the data were analyzed using the SPSS 25.0 program. Results: First, an examination of the perception of part-time substitute teacher support projects based on the type of daycare center revealed significant differences in all aspects, except for whether they choose to reapply. Second, an analysis of the demand for part-time substitute teacher support projects, categorized by the type of daycare center, indicated significant differences. Conclusion/Implications: The findings of this study furnish valuable insights for the equitable and effective implementation of the part-time substitute teaching assistant support project, taking into account the distinct characteristics of various daycare centers. Additionally, the results offer essential foundational data to guide the strategic direction of the part-time substitute teaching assistant support project.

• 산업공학
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• 제15권4호
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• pp.439-443
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• 2002

In this paper, we study to evaluate the relative time required to perform the CT scanning in the PACS versus a film-based system and helical versus non-helical studies. Time studies were performed in 175 consecutive CT scanning. Images from 85 examinations were electronically transferred to a PACS, and 90 were printed to film. The time required to obtain and electronically transfer the images or print the images to film and make the current and previous studies available to the radiologists for interpretation was recorded. The time required for a radiological technologist to complete a CT test was reduced by 43% with the PACS compared with the film-based system and nonhelical was reduced 10~20% with helical studies. This reduction was due to the elimination of a transfer and printing, such as the printing at window or level settings. The use of PACS can result in the elimination of time tasks for the radiological technologist, resulting in marked reduction in examination time. This reduction can result in decreased cost and increased productivity in PACS operation.

• 한국임상약학회지
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• 제9권2호
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• pp.119-126
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• 1999

The educational backgrounds and research interests of pharmacy educators in Korea were analyzed to investigate the possibility of migrating the pharmacy education system from basic science-oriented to pharmacy practice-oriented. There are 257 full-time faculty members and 190 part-time members in twenty pharmacy colleges in 1999. Most of the full-time professors are majoring in basic pharmacy areas focused on the drug itself. Thirty nine percent of full-time professors are specialized in the fields of Medicinal Chemistry, $20\%$ in Biochemistry, $19\%$ in Pharmaceutics, and $18\%$ in Pharmacology-Toxicology. Only $4\%$ are related to the Pharmacy Practice Field. When we consider only the educational backgrounds of the educators, $89\%$ of full-time professors are related to the subjects of Korean Pharmacists Licensure Examination. Changes in educator's inclination will lead to the changes in pharmacy education and the contents of the test. There will be at least 38 job-openings due to retirements within next five years, and this will lead to approximately $15\%$ changes of current full time professors in Korean pharmacy education. More full-time professors will be needed in the area of pharmacy practice in order to focus on the pharmacy practice-oriented pharmacy education. Many distinguished characteristics of pharmacy educators between the private schools and the national universities are also discussed in the paper.

• 한국실내디자인학회논문집
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• 제16권2호
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• pp.347-356
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• 2007

The concept of time-space to be seen in the modem society has complex features at the points of scientific, philosophical, artistic, religious point of view. It has been brought up at a points of neo centric religious, philosophical view and then after, phenomenal approach and scientific approach were rendered through Newton and Einstein and so many scholar approaches affected the artistic field significantly. With such visual expression, it has affected the paintings for a long time till the 19th century, and then has affected various fields such as photography, film, video, computer, architecture and has currently affected the various space expressive of our daily lives and virtual space of digital. This study is to extract a visual and expressionistic characteristic through historical examination and multi-scholar analysis of time-space concept. Especially, by expanding the previous time and space concept, experimental cases and expressionistic characteristics has come up on the media art that offers various experience and by analyzing the expressionistic characteristics of the time-space concept expressed in media art, it is to extract the basic factors for the diversity of space experience.

• 대한핵의학회지
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• 제23권1호
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• pp.41-48
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• 1989

$^{99m}Tc-Pertechnetate\;(TcO_4^-)$ is concentrated by the stomach after intravenous injection, allowing the detection of ectopic gastric mucosa. It has been used to develop a noninvasive test of gastric secretion. However the cellular site of concentration is still controversial, that is whether mucin-secreting epithelial cell or acid-secreting parietal cell. This study is planned to investigate the effects of cimetidine and gastric acidity on the retention of $TcO_4^-$ in the gastric wall of the rat. Also we further attempted to clarify the uptake and secreting cell of $TcO_4^-$ in the gastric mucosa. One hundred rats were divided into two groups, preliminary (40 rats) and main examination group (60 rats). Preliminary examination group was composed of fasting group (20 rats) for the detection of the time for reaching stable $TcO_4^-$ retention ratio in gastric wall and post-prandial group (20 rats) for the detection of the time for reaching the maximal gastric acidity. Main examination group was composed of fasting group (30 rats), which was subdivided into control group (10 rats), cimetidine group (10rats), $Mylanta^{(R)}$ group (10 rats) and post?prandial group (30 rats), which was subaivided into 90 min group (10 rats), 90 min cimetidine group (10 rats), and 120 min group (10 rats). Retention ratio (%) of $TcO_4$ in the gastric wall and the pH of the gastric contents were measured in the extracted stomach of the six groups. Gastric wall retention ratio of $TcO_4^-$ was calculated by the gastric wall radioactivity (cpm) divided by total gastric radioactivity (cpm) at 30 mins after intravenous injection of 0.4 mCi of $TcO_4^-$. The results were as follows: 1) The time required for reaching stable $TcO_4$ retention ratio and the lowest gastric PH were 30 min and 90 min, respectively. 2) In the fasting group, the gastric wall retention ratio of $TcO_4^-$ was significantly increased in the cimetidine group, compared with the control group (P < 0.01). However there was no significant difference between the control and $Mylanta^{(R)}$ group 3) The $TcO_4^-$ retention ratios of 90 min and 120 min groups were lower than that of the fasting control group (p < 0.05), either. After administration of cimetidine, the retention ratio was significantly increased in 90 min group (p < 0.01). 4) While $TcO_4^-$ retention ratio and gastric pH were well correlated in the post-prandial 120 min group (r=0.7112, p<0.05), in the post-prandial 90 min and 90 min cimetidine groups correlated poorly. However, there was no correlation in the three fasting groups at all. Referring the above results, we infer that $TcO_4^-$ is secreted into the gastric lumen by both parietal and non-parietal cells, with dominant non-parietal $TcO_4^-$ secretion in the fasting state and dominant parietal $TcO_4^-$ secretion in the stimulated state.