Radiation Oncology Journal
- Volume 11 Issue 1
- /
- Pages.91-96
- /
- 1993
- /
- 2234-1900(pISSN)
- /
- 2234-3156(eISSN)
The Role of High Dose Rate (HDR) Intracavitary Radiation Therapy for the Management of Nasopharyngeal Carcinoma
비인강암 환자의 고선량 강내 방사선 치료의 효과
- Cho, Jeong-Gill (Department of Radiation Oncology, Asan Medical Center, College of Medicine, University of Ulsan) ;
- Chang, Hye-Sook (Department of Radiation Oncology, Asan Medical Center, College of Medicine, University of Ulsan) ;
- Choi, Eun-Kyung (Department of Radiation Oncology, Asan Medical Center, College of Medicine, University of Ulsan)
- 조정길 (울산대학교 의과대학, 서울중앙병원, 치료방사선과학교실) ;
- 장혜숙 (울산대학교 의과대학, 서울중앙병원, 치료방사선과학교실) ;
- 최은경 (울산대학교 의과대학, 서울중앙병원, 치료방사선과학교실)
- Published : 1993.06.01
Abstract
From September 1989 to June 1992,22 patients with nasopharyngeal carcinoma were treated in Asan Medical Center with an external beam of 60 Gy followed by a boost dose of 15 Gy HDR brachytherapy. There were 5 females and 17 males with median age of 44 years (range: 20-69 years). All patients were histologically confirmed and staged by physical examination, CT scan and/or MRI. By the AJCC TNM staging system, there were 2 patients with stge II (T2NO), 4 with stage III (T3NO, T1-3N1), and 16 with stage IV (T4 or N2-3). Four patients received chemotherapy with 5-FU and cisplatin prior to radiotherapy. All patients were followed up periodically by a telescopic examination and radiologic imaging study of CT scan or MRI with a median follow-up time of 13 months (range: 3-34 months). Twenty one patients showed a complete response ore month after completing therapy and one patient showed a complete response after three months. At the time of this analysis, seventeen patients remain alive without evidence of disease, but four patients developed distant metastasis and one patient died a month after treatment. The local control rate was