• Title/Summary/Keyword: Time mixture

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Enhancement of Anticancer Activity by Combination of Garlic (Allium sativum) Extract and Vitamin C (마늘 추출물과 비타민 C 혼합물에 의한 암세포증식억제의 상승 효과)

  • 황우익;손향은;이지영;김동청
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.30 no.2
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    • pp.372-376
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    • 2001
  • The effect of garlic extract and vitamin C mixture on the various cancer cell lines in vitro and in vivo have been examined. Proliferation of human colon cancer (HT-29), human rectal cancer (HRT-18) and human hepatoma (HepG2) cells was inhibited by garlic extract and vitamin C, respectively. Based on the cytotoxic activity, mixture of garlic extract and vitamin C was demonstrated to possess a synergistic growth inhibition on HT-29, HRT-18 and HepG2 cancer cells. Mixture of garlic extract and vitamin C significantly arrested G2/M phase cells in the HepG2 cell cycle. Oral administration of mixture of garlic extract and vitamin C to sarcoma-180 tumor-bearing mice prolonged survival time compared to that of control group. These results suggested that addition of vitamin C enhances anticancer activity of garlic extract in vitro, and mixture of garlic extract and vitamin C has antitumor effect in vivo.

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Physical properties of Reinforced soil Mixture powder (보강혼합토분의 물리적 특성)

  • 이상호
    • Magazine of the Korean Society of Agricultural Engineers
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    • v.42 no.5
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    • pp.125-132
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    • 2000
  • This study was performed to evaluate the physical properties of reinforced soil mixture powder. Soil sample was prepared by passing into the standard sieve of No. 200 and reinforcement materials were calcium carbonate, quicklime and portland cement. Fineness, setting time, and compressive strength test for reinforced soil mixture powder were performed and analyzed to investigate their physical properties. The main results were summarized as follow. The compressive strength of soil mixture powder itself and most reinforced was reinforced according to increasing in the mixture rate of reinforcement and the rate of increase was remarkably higher in the cement reinforced soil moisture powder. It was appeared that the early compressive strength is considering higher in the cement reinforced soil moisture powder with 2% of moisture rate of accelerator.

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Fundamental Properties and Adiabatic Temperature Rise of Concrete with the Combination of Mineral and Chemical Admixture (혼화재료의 조합사용에 따른 콘크리트의 기초물성 및 단열온도상승 특성)

  • Jeon Chung Keun;Kim Jong;Shin Dong-An;Yoon Gi-Won;Han Cheon Goo
    • Proceedings of the Korea Concrete Institute Conference
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    • 2005.05b
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    • pp.345-348
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    • 2005
  • This paper presents the result of adiabetic temperature rise and fundamental properties of concrete combining admixtures. According to results, difference of setting time with I5.5hours is observed between S-P and R-F30 mixture. Based on the adiabetic temperature rise test, 8$^{circ}C$of heat producted occurs between E-P and R-F30 mixture. is applied to estimate the temperature rising under adiabetic curing condition, which exhibits closer consistency with tested value. The function mentioned above can account for the effect of dormant period in hydration process at early stage on hydration heat production. It reveals that the consideration of placing layer based on the mixture adjustment(E-P mixture at top layer and R-F30 mixture at bottom layer) in mass concreting will contribute to reduce hydration heat as well as alleviate tensile stress discrepancy between placing layer.

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Phyto-toxicological Effects of PAHs on the Germination and Growth of Alfalfa, Barley, and Tall Fescue (종자 발아율 지표 및 초기 묘조 성장에 의한 다환방향족탄화수소의 식물 독성 측정)

  • Kim, Yong-Bum;Chung, Yong
    • Environmental Analysis Health and Toxicology
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    • v.17 no.1
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    • pp.29-35
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    • 2002
  • The test of germination has been used as a good indicator to assess the toxicity of chemicals to plant. This study was carried out to investigate the effect of PAHs, anthracene and phenanthrene, on germination ratio, germination index and germination time of barley, tall fescue and alfafa. Anthracene and phenathrene induced to decrease the seedling length and increase the germination time of the experimental plants. But they did not affect the maximum germination ratio. While it was not correlated between seedling length and final germination ratio, it was shown a close relationship between seedling length and mean germination time of the plants. These results suggested that the mean of germination time and seedling growth could be useful to exmine the phyto -toxicological effect of PAHs. The mixture of anthracene and phenanthrene was examined to investigate the combined effect on seedling length; the mixture induced the reduction of seedling. This was meant that the mixture toxicity of PAHs might be not shown in the sum of each chemical toxicity.

Case study of SAMSUNG TFT-LCD Technology Innovation using TRIZ method (트리즈 기법을 활용한 삼성전자의 TFT-LCD 기술혁신 사례연구)

  • Ban, Byeong-Seob
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.15 no.6
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    • pp.3429-3434
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    • 2014
  • In the TFT-LCD(Thin Film Transistor-Liquid Crystal Display) panel manufacturing industry, SAMSUNG, a late entry, can catch up to leading first mover, SHARP. The changes the note, monitor, TV, and mobile markets in the TFT-LCD industry were studied using a system analysis method. In addition, the fast response time technology in SAMSUNG TFT-LCD technology was developed using the TRIZ method. For example, a new liquid crystal mixture of a wide view angle and fast response time were developed by doping a new high birefringence liquid crystal material in a base mixture using the contradiction method and su-field method of TRIZ. The response time of a new liquid crystal mixture was improved to approximately 60%(16.2ms with base LC mixture, 9.8ms with a new LC mixture).

A Study on Market Segmentations and Shopping Orientations of Home Shopping User: Based on Mixture Model (Mixture model에 의한 홈쇼핑 이용자 시장세분화와 쇼핑성향)

  • Seo, Jeong-Ah;Lee, Jin-Hwa;Hong, Jae-Won
    • Journal of the Korean Society of Clothing and Textiles
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    • v.32 no.7
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    • pp.1023-1033
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    • 2008
  • The purpose of this study was to segment home-shopper market by using the demographic characteristics. This study enables a better unders landing of home-shoppers and improving the strategy of marketing. The specific objects of this study are as follow: First, it was to exam market segmentations by demographic factors using mixture model. Second, it was to exam shopping orientations of fashion merchandise according to segmentation groups. The data was collected from 637 subjects who had used the home shopping more than one time in a year. The data was analysised through frequencies, factor analysis, ANOVA, Duncan's mutiple range tests with SPSS 12.0 and Mixture model. The results of data are as follows: 1. The result of market segmentation as demographic factor using Mixture model was extracted to 4 market segments called 20's/ unmarried stage, 30's/ children bearing & rearing stage, 40's/ families with children's education stage, 50's/ aging stage. 2. Shopping orientations were extracted to 5 factors called a pleasure oriented, convenience oriented, off-line oriented, human oriented, thrift oriented.

Bayesian Curve Clustering in Microarray

  • Lee, Kyeong-Eun;Mallick, Bani K.
    • 한국데이터정보과학회:학술대회논문집
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    • 2006.04a
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    • pp.39-42
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    • 2006
  • We propose a Bayesian model-based approach using a mixture of Dirichlet processes model with discrete wavelet transform, for curve clustering in the microarray data with time-course gene expressions.

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A Bivariate Two Sample Rank Test for Mixture Distributions

  • Songyong Sim;Seungmin Lee
    • Communications for Statistical Applications and Methods
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    • v.3 no.2
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    • pp.197-204
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    • 1996
  • We consider a two sample rank test for a bivariate mixture distribution based on Johnson's quantile score. The test statistic is simple to calculate and the exact distribution under the null hypothesis is obtained. A numerical example is given.

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Esterification of High Concentration Free Fatty Acid in Rice Bran Oil (미강유 중 고농도 자유지방산의 에스테르화)

  • Shin, Yong-Seop
    • Journal of Environmental Science International
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    • v.17 no.2
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    • pp.211-224
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    • 2008
  • Characteristics of the esterification reaction between free fatty acid in rice bran oil and methanol was investigated in the presence of catalysts, such as PTS(p-toluene sulfonic acid), Amberlyst 15 dry and SCX(silica gel based strong cation exchange resin). While reaction temperature was kept constant at $65^{\circ}C$, initial feed content of free fatty acid was varied from 100% to 1% by addition of pure free fatty acid which was previously made from rice bran oil. Also, the effect of mole ratio of methanol to fatty acid on the final conversion was examined. When esterification of pure free fatty acid was catalyzed by several acids, final conversions were increased in order of Amberlyst 15 dry, SCX and PTS. Using PTS catalyst, initially the reaction proceeded in homogeneous 2nd oder reaction mechanism. However, phase of reaction mixture changed from homogeneous to heterogeneous along the reaction time and then reaction rate was retarded by mass transfer resistance of methanol. Final conversion of free fatty acid in reaction mixture was depended on initial feed content of free fatty acid, and had maximum value at 30% of initial feed free fatty acid content for all kinds of catalysts used. And the final conversion was increased with mole ratio of methanol by the improvement of reaction rate. When initial feed free fatty acid content below 10% and the reaction was catalyzed by PTS, concentration of free fatty acid in reaction mixture was increased in the middle of reaction time by hydrolysis of triglyceride in reaction mixture. Also, if silica gel was added into the reaction mixture which had initial feed free fatty acid content below 50%, final conversion was increased by the adsorption of moisture produced. The SCX catalyst made the esterification reaction of free fatty acid to progress like in case of PTS catalyst. However, when initial feed free fatty acid content below 10%, concentration of free fatty acid in. reaction mixture was decreased monotonically and not increased in the middle of reaction time on the contrary to the case of PTS. Thus, SCX catalyst accomplished more high value of final conversion than PTS catalyst for the initial feed fatty acid content range from 50% to 5% In case of initial feed free fatty acid content of 1% and mole ratio of methanol was 2, concentration of free fatty acid in reaction mixture increased over the initial feed free fatty acid content for all kind of catalysts used. Although SCX catalyst was added into reaction mixture which had 1% of initial feed fatty acid content, final conversion was hardly raised by mole ratio of methanol.

Comparison of Saccharina japonica-Undaria pinnatifida Mixture and Minoxidil on Hair Growth Promoting Effect in Mice

  • Park, Ki Soo;Park, Dae Hwan
    • Archives of Plastic Surgery
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    • v.43 no.6
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    • pp.498-505
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    • 2016
  • Background Algae have traditionally been used for promotion of hair growth. Use of hair regrowth drugs, such as minoxidil, is limited due to side effects. The aim of this study was to examine a mixture of Saccharina japonica and Undaria pinnatifida (L-U mixture) on hair growth and to compare the promoting effect of hair growth by a 3% minoxidil and a L-U mixture. Methods To evaluate the hair growth-promoting activity, saline, 50% ethanol, 3% minoxidil, and the L-U mixture were applied 2 times a day for a total of 14 days on the dorsal skin of C57BL/6 mice after depilation. Analysis was determined by using a high-resolution hair analysis system, real-time polymerase chain reaction, and H&E staining. Results On day 14, the hair growth effect of the L-U mixture was the same as that of the 3% minoxidil treatment. The L-U mixture significantly (P<0.05) stimulated hair growth-promoting genes, as vascular endothelial growth factor (VEGF) and insulin-like growth factor -1. Increase of VEGF was observed in the L-U mixture group compared with minoxidil and the negative control. In contrast, the L-U mixture suppressed the expression of transforming growth factor-${\beta}1$, which is the hair loss-related gene. In histological examination in the L-U mixture and minoxidil groups, the induction of an anagen stage of hair follicles was faster than that of control groups. Conclusions This study provides evidence that the L-U mixture can promote hair growth in mice, similar to the effect from minoxidil, and suggests that there is potential application for hair loss treatments.