• 대한의용생체공학회:의공학회지
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• 제37권2호
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• pp.84-89
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• 2016

In this study, we proposed ameliorated method for region of interest (ROI) study to improve its accuracy using partial volume effect (PVE). PVE which arose in volumetric images when more than one tissue type occur in a voxel, could be used to reduce an amount of gray matter and cerebrospinal fluid within ROI of diffusion tensor image (DTI). In order to define ROIs, individual b0 image was spatially aligned to the JHU DTI-based atlas using linear and non-linear registration (http://cmrm.med.jhmi.edu/). Fractional anisotropy (FA) and mean diffusivity (MD) maps were estimated by fitting diffusion tensor model to each image voxel, and their mean values were computed within each ROI with PVE threshold. Participants of this study consisted of 20 healthy controls, 27 Alzheimer's disease and 27 normal-pressure hydrocephalus patients. The result showed that the mean FA and MD of each ROI were increased and decreased respectively, but standard deviation was significantly decreased when PVE was applied. In conclusion, the proposed method suggested that PVE was indispensable to improve an accuracy of DTI ROI study.

• Communications for Statistical Applications and Methods
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• 제18권2호
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• pp.171-177
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• 2011

실생활에서 얻어지는 자료에서 근사함수를 구성하기 위하여 모델링을 하기 전에 측정된 원자료로부터 이상치를 제거하는 것이 필요하다. 기존의 이상치 진단의 방법들은 시각화나 최대 잔차들을 이용해왔다. 그러나 종종 다차원의 입력자료를 가지는 비선형함수에 대한 이상치 진단은 좋지 않은 결과를 얻었다. 다차원 입력자료를 갖는 비선형함수에 대한 전형적인서포트 벡터 회귀에 기초한 이상치 진단방법들은 좋은 수행능력을 얻어지지만, 계산비용이나 모수들의 보정 등의 실질적인 문제점들을 가지고 있다. 본 논문에서 계산비용을 감소하고 이상치의 문턱을 적절히 정의하는 서포트 벡터회귀를 이용한 이상치 진단의 실질적인방법을 제안한다. 제안한 방법을 실제자료들에 적용하여 타당성을 보일 것이다.

• Journal of Biosystems Engineering
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• 제38권2호
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• pp.129-137
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• 2013

Purpose: Modeling has been used for elucidating the mechanism of complex biosystems. In spite of importance and uniqueness of adolescent calcium (Ca) metabolism characterized by a threshold Ca intake, its regulatory mechanism has not been covered and even not proposed. Hence, this study aims at model-based proposing potential mechanisms regulating adolescent Ca metabolism. Methods: Two different hypothetic mechanisms were proposed. The main mechanism is conceived based on Ca-protein binding which induces renal Ca filtration, while additional mechanism assumed that active renal Ca re-absorption regulated Ca metabolism in adolescents. Mathematical models were developed to represent the proposed mechanism and simulated them whether they could produce adolescent Ca profiles in serum and urine. Results: Simulation showed that both mechanisms resulted in the unique behavior of Ca metabolism in adolescents. Based on the simulation insulin-like growth factor-1 (IGF-1) is suggested as a potential regulator because it is related to both growth, a remarkable characteristic of adolescence, and Ca metabolism including absorption and bone accretion. Then, descriptive modeling is employed to conceptualize the hypothesized mechanisms governing adolescent Ca metabolism. Conclusions: This study demonstrated that modeling is a powerful tool for elucidating an unknown mechanism by simulating potential regulatory mechanisms in adolescent Ca metabolism. It is expected that various analytic applications would be plausible in the study of biosystems, particularly with combination of experimental and modeling approaches.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제11권9호
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• pp.4180-4196
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• 2017

In this paper, we analyze average capacity of an amplify-and-forward (AF) cooperative communication system model in multi-relay multiuser networks. In contrast to conventional cooperative networks, relays in the considered network have no embedded energy supply. They need to rely on the energy harvested from the signals broadcasted by the source for their cooperative information transmission. Based on this structure, a two-step selection scheme is proposed considering both channel state information (CSI) and battery status of relays. Assuming each relay has infinite or finite energy storage for accumulating the energy, we use the infinite or finite Markov chain to capture the evolution of relay batteries and certain simplified assumptions to reduce computational complexity of the Markov chain analysis. The approximate closed-form expressions for the average capacity of the proposed scheme are derived. All theoretical results are validated by numerical simulations. The impacts of the system parameters, such as relay or user number, energy harvesting threshold and battery size, on the capacity performance are extensively investigated. Results show that although the performance of our scheme is inferior to the optimal joint selection scheme, it is still a practical scheme because its complexity is much lower than that of the optimal scheme.

• 한국축산시설환경학회지
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• 제20권2호
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• pp.41-48
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• 2014

This study was conducted to investigate the dispersion prediction of odor from swine farms in Korea. Gaussian Plume model used in considering of farm size, wind velocity, atmospheric stability and threshold odor unit to prediction of odor dispersion based on the survey on current state of odor emission and control from 48 site of swine farms. Farm size, wind velocity and atmospheric stability were affected the distance of odor dispersion, showed longer distance in cases of large farm, low wind velocity and stable atmospheric condition. We will suggestion the adjusted distance of odor dispersion according to farm size was estimated to 180 m in small farm and 320 m in large farm when apply the 3 OU, 5 m/s wind velocity and stable atmospheric condition.

• Geomechanics and Engineering
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• 제1권3호
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• pp.193-204
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• 2009

A 10.4-m high highway embankment retained behind mechanically stabilized earth (MSE) walls is under construction in the northeastern part of the Indian state of Bihar. The structure is constructed with compacted, micaceous, grey, silty sand, reinforced with polyester (PET) geogrids, and faced with reinforced cement concrete fascia panels. The connections between the fascia panels and the geogrids failed on several occasions during the monsoon seasons of 2007 and 2008 following episodes of heavy rainfall, when the embankment was still under construction. However, during these incidents the MSE embankment itself remained by and large stable and the collateral damages were minimal. The observational data during these incidents presented an opportunity to develop and calibrate a simple procedure for estimating rainfall induced pore water pressure development within MSE embankments constructed with backfill materials that do not allow unimpeded seepage. A simple analytical finite element model was developed for the purpose. The modeling results were found to agree with the observational and meteorological records from the site. These results also indicated that the threshold rainwater infiltration flux needed for the development of pore water pressure within an MSE embankment is a monotonically increasing function of the hydraulic conductivity of backfill. Specifically for the MSE embankment upon which this study is based, the analytical results indicated that the instabilities could have been avoided by having in place a chimney drain immediately behind the fascia panels.

• 고려인삼학회:학술대회논문집
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• 고려인삼학회 1984년도 학술대회지
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• pp.141-144
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• 1984

인삼이 강장제인 약용식물로 인식됨에 따라 세포에 대한 인삼 추출물의 효과를 연구하기 위해 미생물을 실험재료로 연구한 결과, 인삼이 두 단계로 세포 호흡에 영향을 미치는 것으로 관찰되었으며 (Tso and Fung, Microbios, Lett. 13 : $7{\~}12$., Tso, Acta Microbiologies sinica 21 : $53{\~}56$)이것은 세포 에너지 대사 변화에 중요한 역할을 할 수 있다는 것을 시사해 주었다. 이와 같은 결과로 인삼이 세포의 mitochondria 에 의한 산소 소모에 미치는 효과를 검토한 결과, 일정한 pH 조건하에서 인삼은 호흡을 촉진시켰으며, 일정농도 이상 투여하였을 경우 다소의 억제효과를 보였다. 위의 결과들은 세포의 mitochonbria 호흡에 미치는 인삼의 효과를 재확인하는 것으로 강장제로서의 인삼의 가치를 뒷받침해 주고 있다.

• Nuclear Engineering and Technology
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• 제39권5호
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• pp.627-636
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• 2007

The present work is aimed at further discussing the effectiveness of dimensionless parameters recently proposed for the analysis of flow stability in heated channels with supercritical fluids. In this purpose, after presenting the main motivations for the introduction of these parameters in place of previously proposed ones, additional information on the theoretical bases and on the consequences of this development is provided. Stability maps, generated by an in-house program adapted from a previous application to boiling channels, are also shown for different combinations of the operating parameters. The maps are obtained as contour plots of an amplification parameter obtained from numerical discretization and subsequent linearization of governing equations; as such, they provide a quantitatively clear perspective of the effect of different boundary conditions on the stability of heated channels with supercritical fluids. In order to assess the validity of the assumptions at the basis of the in-house model, supporting calculations have been performed making use of the RELAP5/MOD3.3 computer code, detecting the values of the dimensionless parameters at the threshold for the occurrence of instability for a heated channel representative of SCWR proposed core configurations. The obtained results show reasonable agreement with the maps, supporting the applicability of the proposed scaling parameters for describing the dynamic behaviour of heated channels with supercritical fluids.

• Nuclear Engineering and Technology
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• 제10권2호
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• pp.65-72
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• 1978

원자로 가동시, 정상상태에서 벗어나 갑작스럽게 출력이 바뀔 때 발생하는 응력의 집중과 핵 분열시 발생하는 요오드의 부식에 의해서 생기는 피복물질의 응력 부식파괴현상을 이해하기 위하여, 이번 실험에서는 지르칼로이-4(Zicaloy-4)관을 사용하여 요오드응력부식 실험을 원자로 안의 상태에 가깝도록 30$0^{\circ}C$의 상태아래서 행하였다. 요오드 농도에 따라서 지르칼로이-4, 관(Tube)의 응력부식에 한 파괴시간을 구했고, 응력부식을 일으킬 수 있는 임계요오드 농도 및 임계접선방향의 응력을 구하였다. 요오드에 의한 응력부식이 화학석인 반응이라기 보다는 기계적인 반응성격을 갖기 때문에 응력부식을 파괴 역학적인 관점에서 설명하고자 응력과 파괴시간을 함수관계로 다음과 같이 표시해 보았다. log t$_{F}$ =5.5- (3/2) log$_{c}$-4log$\sigma$ t$_{F}$ : 파괴시간(") c : 요오드농도(mg/㎤) $\sigma$ : 응력 ($10^4$psi).

• Journal of Magnetics
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• 제6권4호
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• pp.132-141
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• 2001

The switching characteristics and the magnetization-flop behavior in magnetic tunnel junctions exchange biased by synthetic antiferromagnets (SyAFs) are investigated by using a computer simulations based on a single-domain multilayer model. The bias field acting on the free layer is found to be sensitive to the thickness of neighboring layers, and the thickness dependence of the bias field is greater at smaller cell dimensions due to larger magnetostatic interactions. The resistance to magnetization flop increases with decreasing cell size due to increased shape anisotropy. When the cell dimensions are small and the synthetic antiferromagnet is weakly, or not pinned, the magnetization directions of the two layers sandwiching the insulating layer are aligned antiparallel due to a strong magnetostatic interaction, resulting in an abnormal magneto resistance (MR) change from the high-MR state to zero, irrespective of the direction of the free-layer switching. The threshold field for magnetization-flop is found to increase linearly with increasing antiferromagnetic exchange coupling in the synthetic antiferromagnet. Irrespective of the magnetic parameters and cell sizes, magnetization flop does not exist near zero applied field, indicating that magnetization flop is driven by the Zeeman energy.