• Journal of Integrative Natural Science
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• v.9 no.4
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• pp.234-240
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• 2016

Bradykinin receptor B2, a GPCR protein, binds with the inflammatory mediator hormone bradkynin. It plays an important role in cross-talk between the renin-angiotensin system (RAS) and the kinin-kallikrein system (KKS). Also, it is involved in many processes including vasodilation, edema, smooth muscle spasm and pain fiber stimulation. Hence, studuying the structural features of the receptor becomes important. But the unavailability of the three dimensional structure of the protein makes the analysis difficult. Hence we have performed the homology modelling of Bradykinin receptor B2 with 5 different templates. 25 different homology models were constructed. Two best models were selected based on the model validation. The developed models could be helpful in analysing the structural features of Bradykinin receptor B2 and in pathophysiology of various disorders related to them.

• Proceedings of the Korean Geotechical Society Conference
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• 2008.10a
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• pp.1614-1622
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• 2008

A series of three-dimensional numerical modelling have been conducted to clarify the behaviour of multi-pressurised soil nails with high strength steel pipes. In this study, the soil non-linearity, the soil-nail interaction and staged construction are considered. It has been found that pressurised soil nails can reduce lateral ground movement by 14-21% compared to general soil nails with very low pressure. In addition, ground settlement was reduced when using multi-pressurised soil nails. The pressurised soil nail may result in an increase in the surcharge loading on the ground surface.

• Structural Engineering and Mechanics
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• v.6 no.4
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• pp.439-455
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• 1998

A three-dimensional static nonlinear finite element analysis was performed on the NUPEC large-scale flanged shear wall, which was the subject of an international study program. Details of the constitutive models and analysis procedures used are provided, and the results of the analysis are presented and discussed. The analytical results are compared to the experimentally observed behaviour, and reasonable correlation is observed. Deficiencies in the modelling are identified. In addition, a parametric study is undertaken to investigate factors and mechanisms influencing both the observed behaviour and the calculated response. Finally, a cyclic load analysis of the wall is described and discussed. The paper serves to point out aspects in modelling that are critical to both producing realistic results, and correctly interpreting those results.

• Structural Engineering and Mechanics
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• v.72 no.2
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• pp.257-273
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• 2019

In this paper, the mechanical behaviour of functionally graded material beams is studied using the 3D Saint-Venant's theory, in which the section is free to warp in and out of its plane (Poisson's effects and out-of-plane warpings). The material properties of the FGM beam are distributed continuously through the thickness by several distributions, such as power-law distribution, exponential distribution, Mori-Tanaka schema and sigmoid distribution. The proposed method has been applied to study a simply supported FGM beam. The numerical results obtained are compared to other models in the literature, which show a high performance of the 3D exact theory used to describe the stress and strain fields in FGM beams.

• Magazine of korean Tunnelling and Underground Space Association
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• v.21 no.2
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• pp.117-129
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• 2019

Tunnelling in urban environments is very common nowadays as large cities are expanding and transportation demands require the use of the underground space for creating extra capacity. Inevitably, any such new construction may have significant effects on existing nearby infrastructure and therefore relevant assessment of structural integrity and soil-structure interaction is required. Foundation piles can be rather sensitive to nearby tunnel construction and therefore their response needs to be evaluated carefully. Although detailed three-dimensional continuum finite element analysis can provide a wealth of information about this behaviour of piles, such analyses are generally very computationally demanding and may require a number of material and other model parameters to be properly calibrated. Therefore, relevant simplified approaches are used to provide a practical way for such an assessment. This paper presents a simple method where the pile is modelled with beam finite elements, pile-soil interaction is modelled with soil springs and tunnelling-induced displacements are introduced as an input boundary condition at the end of the soil springs. The performance of this approach is assessed through some examples of applications.

• Journal of the Korean Society for Precision Engineering
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• v.16 no.2 s.95
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• pp.225-233
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• 1999

This paper describes a versatile finite element technique which has been used to investigate of wide range of structural defects of practical importance. The procedure automatically remeshes the three-dimensional finite element model during the stages of crack growth. Problems analyzed to date include the surface cracks in leak-before-break situations, the development of quarter-elliptical corner defects, planar semi-elliptical surface defects and the fatigue growth of defects.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.11 no.10
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• pp.4759-4780
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• 2017

Full Dimension multiple input multiple output (FD-MIMO) architecture employs a planar array design at the Base Station (BS) to provide high order multi-user MIMO (MU-MIMO) via simultaneous data transmission to large number of users. With FD-MIMO, the BS can also adjust the beam direction in both elevation and azimuth direction to concentrate the energy on the user of interests while minimizing the interference leakage to co-scheduled users in the same cell or users in the neighboring cells. In a typical highly populated macrocell environment, modelling the elevation angular characteristics of three-dimensional (3D) channel is critical to understanding the performance limits of the FD-MIMO system. In this paper, we study the throughput performance of FD-MIMO system with varying elevation angular spread and inter-element spacing using a 3D spatial channel model. Our results show that for a typical urban scenario, horizontal beamforming with correlated antenna spacing achieves optimal performance but by restricting the spread of elevation angles of departure, elevation beamforming achieves high array gain with wide inter-element spacing. We also realize significant gains due to spatial array processing via modelling the elevation domain and varying the inter-element spacing for both the transmitter and receiver.

• Korean Journal of Computational Design and Engineering
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• v.10 no.6
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• pp.432-443
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• 2005

Recent three-dimensional feature-based CAD systems based on solid or non-manifold modelling functionality have been widely used for product design in manufacturing companies. When product models associated with features are used in various downstream applications such as analysis, however, simplified and abstracted models at various levels of detail (LODs) are frequently more desirable and useful than the full detailed model. To provide multi-resolution models, the features need to be rearranged according to a criterion that measures the significance of the feature. However, if the features are rearranged, the resulting shape is possibly different from the original because union and subtraction Boolean operations are not commutative. To solve this problem, in this paper, the new concept of the effective zone of a feature is defined and identified using Boolean algebra. By introducing the effective zone, an arbitrary rearrangement of features becomes possible and arbitrary LOD criteria may be selected to suit various applications. Besides, because the effective zone of a feature is independent of the data structure of the model, the multi-resolution modelling algorithm based on the effective zone can be implemented on any 3D CAD system based on conventional solid representations as well as non-manifold topological (NMT) representations.

• Proceedings of the Korea Institute of Fire Science and Engineering Conference
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• 1997.11a
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• pp.112-119
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• 1997

The modelling of carbon substances obtaining, for instance, carbon fibers which have high fire resistance, has been realized on the example of the polyacrylonitrile pyrolysis modelling. The pyrolysis is considered as a double step process when the formation of a liquid phase and the oxidation of substance are excluded. Three main reactions are considered: a) with the evolution of ammonia; b) with the evolution of hydrogen cyanide; c) with the evolution of hydrogen. Reactions b) and c) are sequential, and a) and b) are parallel. The problem is formulated as one-dimensional. The equations of energy, masses or concentrations, porosity and thermal conductivity are proposed. The mathematical model of the carbonization process is designed using tile kinetic characteristics of the above reactions and the thermodynamic parameters of reagents and products in these reactions. The equations received are calculated by Runge-Cutta method and by Adams method of the fourth order accuracy.

• Water for future
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• v.16 no.4
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• pp.221-236
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• 1983

In semi-enclosed shallow sea areas typified by the Yellow sea and the East China Sea, currents and sea surface variations are predominantly tidal. During the recent years two-dimensional numerical hydrodynamic model of the Yellow Sea and the East China Sea has been developed, based on the vertically-integrated equations of motion and continuity, capable of reproducing amplitudes and phases of the principal components of tides to satisfiable accuracy. As a subsequent development a three-dimensional hydrodynamical nymerical model covering the Yellow Sea and the East China Sea has been formulated to investigate the vertical distribution of horizontal tidal current and the response of the continented to investigate the vertical distribution of horizontal tidal current and the response of the continental shelf sea to steady uniform wind stress field imposed over the surface. Features of the M2 tidal current and the wind-induced three-dimensional current structure determined from the computation have been examined and discussed.