• Title/Summary/Keyword: Therapy Beam

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Dosimetry for Total Skin Electron Beam Therapy in Skin Cancer (피부암치료를 위한 전자선 전신피부 치료방법과 선량분포 측정)

  • Chu, Sung-Sil;Loh, John-Jk;Kim, Gwi-Eon
    • Radiation Oncology Journal
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    • v.10 no.1
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    • pp.107-113
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    • 1992
  • Increasing frequency of skin cancer, mycosis fungoides, Kaposi's sarcoma etc, it need to treatment dose planning for total skin electron beam (TSEB) therapy. Appropriate treatment planning for TSEB therapy is needed to give homogeneous dose distribution throughout the entire skin surface. The energy of 6 MeV electron from the 18 MeV medical linear accelerator was adapted for superficial total skin electron beam therapy. The energy of the electron beam was reduced to 4.2 MeV by a $0.5\;cm\times90\;cm{\times}180\;cm$ acryl screen placed in a feet front of the patient. Six dual field beam was adapted for total skin irradiation to encompass the entire body surface from head to toe simultaneously. The patients were treated behind the acryl screen plate acted as a beam scatterer and contained a parallel-plate shallow ion chamber for dosimetry and beam monitoring. During treatment, the patient was placed in six different positions due to be homogeneous dose distribution for whole skin around the body. One treatment session delivered 400 cGy to the entire skin surface and patients were treated twice a week for eight consecutive weeks, which is equivalent to TDF value 57. instrumentation and techniques developed in determining the depth dose, dose distribution and bremsstrahlung dose are discussed.

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An Analysis on Treatment Schedule of Carbon Ion Therapy to Early Stage Lung Cancer

  • Sakata, Suoh;Miyamoto, Tadaaki;Tujii, Hirohiko
    • Proceedings of the Korean Society of Medical Physics Conference
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    • 2002.09a
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    • pp.174-176
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    • 2002
  • A total of 134 patients with stage 1 of non-small cell lung cancer treated by carbon ion beam of HIMAC NIRS were investigated for control rate and delivered dose. The delivered dose of every patient was converted to biological effective dose (BED) of LQ model using fraction number, dose per fraction and alpha beta ratio which shows the maximum correlation between BED and tumor control. The BED of every patient was classified to establish a BED response curve for control. Assuming fraction numbers, dose response curves were introduced from BED response curve. The total doses to realize several control rates were obtained for the treatment of small fraction number.

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Evaluation of the effect of mechanical deformation on beam isocenter properties of the SC200 scanning beam delivery system

  • Wang, Ming;Zheng, Jinxing;Song, Yuntao;Li, Ming;Zeng, Xianhu
    • Nuclear Engineering and Technology
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    • v.52 no.9
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    • pp.2064-2071
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    • 2020
  • For proton pencil beam scanning (PBS) technology, the accuracy of the dose distribution in a patient is sensitive to the properties of the incident beam. However, mechanical deformation of the proton therapy facility may occur, and this could be an important factor affecting the proton dose distribution in patients. In this paper, we investigated the effect of deformation on an SC200 proton facility's beam isocenter properties. First, mechanical deformation of the PBS nozzle, L-shape plate, and gantry were simulated using a Finite Element code, ANSYS. Then, the impact of the mechanical deformation on the beam's isocenter properties was evaluated using empirical formulas. In addition, we considered the simplest case that could affect the properties of the incident beam (i.e. if only the bending magnet (BG3) has an error in its mounting alignment), and the effect of the beam optics offset on the isocenter characteristics was evaluated. The results showed that the deformation of the beam position in the X and Y direction was less than 0.27 mm, which meets the structural design requirements. Compared to the mechanical deformation of the L-shape plate, the deformation of the gantry had more influence on the beam's isocenter properties. When the error in the mounting alignment of the BG3 is equal to or more than 0.3 mm, the beam deformation at the isocenter exceeds the maximum accepted deformation limits. Generally speaking, for the current design of the SC200 scanning beam delivery system, the effects of mechanical deformation meet the maximum accepted beam deformation limits. In order to further study the effect of the incident beam optics on the isocenter properties, a fine-scale Monte Carlo model including factors relating to the PBS nozzle and the BG3 should be developed in future research.

Correction of Prompt Gamma Distribution for Improving Accuracy of Beam Range Determination in Inhomogeneous Phantom

  • Park, Jong Hoon;Kim, Sung Hun;Ku, Youngmo;Lee, Hyun Su;Kim, Young-su;Kim, Chan Hyeong;Shin, Dong Ho;Lee, Se Byeong;Jeong, Jong Hwi
    • Progress in Medical Physics
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    • v.28 no.4
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    • pp.207-217
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    • 2017
  • For effective patient treatment in proton therapy, it is therefore important to accurately measure the beam range. For measuring beam range, various researchers determine the beam range by measuring the prompt gammas generated during nuclear reactions of protons with materials. However, the accuracy of the beam range determination can be lowered in heterogeneous phantoms, because of the differences with respect to the prompt gamma production depending on the properties of the material. In this research, to improve the beam range determination in a heterogeneous phantom, we derived a formula to correct the prompt-gamma distribution using the ratio of the prompt gamma production, stopping power, and density obtained for each material. Then, the prompt-gamma distributions were acquired by a multi-slit prompt-gamma camera on various kinds of heterogeneous phantoms using a Geant4 Monte Carlo simulation, and the deduced formula was applied to the prompt-gamma distributions. For the case involving the phantom having bone-equivalent material in the soft tissue-equivalent material, it was confirmed that compared to the actual range, the determined ranges were relatively accurate both before and after correction. In the case of a phantom having the lung-equivalent material in the soft tissue-equivalent material, although the maximum error before correction was 18.7 mm, the difference was very large. However, when the correction method was applied, the accuracy was significantly improved by a maximum error of 4.1 mm. Moreover, for a phantom that was constructed based on CT data, after applying the calibration method, the beam range could be generally determined within an error of 2.5 mm. Simulation results confirmed the potential to determine the beam range with high accuracy in heterogeneous phantoms by applying the proposed correction method. In future, these methods will be verified by performing experiments using a therapeutic proton beam.

Effects of balance imagery of semi-tandem stance on a flat floor and balance beam for postural control: a comparison between older and younger adults

  • Lee, Jeong-Weon;Hwang, Sujin
    • Physical Therapy Rehabilitation Science
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    • v.4 no.2
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    • pp.87-93
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    • 2015
  • Objective: Balance is a preceding task for functional activities in daily activities as well as community-dwelling activities. To learn skilled and functional activities, it is also necessary to imagine an appropriate and effective movement representation used to plan and execute the functional activities. The purpose of this study was to evaluate the effects of balance imagery of semi-tandem stance on a flat floor and balance beam on balance abilities for elderly and young adults. Design: Cross-sectional study. Methods: Fifteen elderly and thirty-four young adults were enrolled in this study. In order to determine whether there is a change in postural control ability according to the different imagery training methods used, standing static balance measurements were performed. According to the therapist's instructions, participants were to stand in a semi-tandem position on the Good Balance System for 1 minute while imagining that they were standing on a balance beam, and while the postural control abilities was assessed. Results: Postural control was significantly different in balance ability of semi-tandem stance on a flat floor compared to on a balance beam in both geriatrics and young adults. Postural sway was more significantly decreased in young adults than older adults during balance imagery of semi-tandem stance on a flat floor as well as on balance beam (p<0.05). Conclusions: The results of this study suggest that the ability to mentally represent their actions was similar in older adults compared to young adults, although older adults showed a drop in efficiency of postural control more than young adults.

Quantifications of Intensity-Modulated Radiation Therapy Plan Complexities in Magnetic Resonance Image Guided Radiotherapy Systems

  • Chun, Minsoo;Kwon, Ohyun;Park, Jong Min;Kim, Jung-in
    • Journal of Radiation Protection and Research
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    • v.46 no.2
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    • pp.48-57
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    • 2021
  • Background: In this study, the complexities of step-and-shoot intensity-modulated radiation therapy (IMRT) plans in magnetic resonance-guided radiation therapy systems were evaluated. Materials and Methods: Overall, 194 verification plans from the abdomen, prostate, and breast sites were collected using a 60Co-based ViewRay radiotherapy system (ViewRay Inc., Cleveland, OH, USA). Various plan complexity metrics (PCMs) were calculated for each verification plan, including the modulation complexity score (MCS), plan-averaged beam area (PA), plan-averaged beam irregularity, plan-averaged edge (PE), plan-averaged beam modulation, number of segments, average area among all segments (AA/Seg), and total beam-on time (TBT). The plan deliverability was quantified in terms of gamma passing rates (GPRs) with a 1 mm/2% criterion, and the Pearson correlation coefficients between GPRs and various PCMs were analyzed. Results and Discussion: For the abdomen, prostate, and breast groups, the average GPRs with the 1 mm/2% criterion were 77.8 ± 6.0%, 79.8 ± 4.9%, and 84.7 ± 7.3%; PCMs were 0.263, 0.271, and 0.386; PAs were 15.001, 18.779, and 35.683; PEs were 1.575, 1.444, and 1.028; AA/Segs were 15.37, 19.89, and 36.64; and TBTs were 18.86, 19.33, and 5.91 minutes, respectively. The various PCMs, i.e., MCS, PA, PE, AA/Seg, and TBT, showed statistically significant Pearson correlation coefficients of 0.416, 0.627, -0.541, 0.635, and -0.397, respectively, with GPRs. Conclusion: The area-related metrics exhibited strong correlations with GPRs. Moreover, the AA/Seg metric can be used to estimate the IMRT plan accuracy without beam delivery in the 60Co-based ViewRay radiotherapy system.

The Usability Evaluation Half Beam Radiation Treatment Technique on the Esophageal Cancer (식도암 환자에서의 Half Beam 치료법의 유용성 평가)

  • Park, Hochoon;Kim, Youngjae;Jang, Seongjoo
    • Journal of the Korean Society of Radiology
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    • v.9 no.5
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    • pp.287-293
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    • 2015
  • Because of esophageal cancer has the long length of the lesion and also inhomogeneous in depth. So, the radiation dose distribution was inhomogeneous in radiation therapy. To overcomes the dose distribution uniformity using half beam method. Patient's CT image was used radiation treatment planning. We used two planning methods that one is the using normal beam and another is using half beam. Than comparing the two radiotherapy planning using target coverage, dose volume histogram, conformity index, homogeneity index and normal tissues - heart, spinal cord, lung -. In results, Treatment planning using half beam is little more than normal beam in target coverage, dose volume histogram, conformity index, homogeneity index and normal tissues covering. However, If the patient is not correct position patients may arise a side effect. Thus, the using in Half beam involving the geometrically exact under lung cancer is considered to advantage.

Test of a Multilayer Dose-Verification Gaseous Detector with Raster-Scan-Mode Proton Beams

  • Lee, Kyong Sei;Ahn, Sung Hwan;Han, Youngyih;Hong, Byungsik;Kim, Sang Yeol;Park, Sung Keun
    • IEIE Transactions on Smart Processing and Computing
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    • v.4 no.5
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    • pp.297-304
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    • 2015
  • A multilayer gaseous detector has been developed for fast dose-verification measurements of raster-scan-mode therapeutic beams in particle therapy. The detector, which was constructed with eight thin parallel-plate ionization chambers (PPICs) and polymethyl methacrylate (PMMA) absorber plates, is closely tissue-equivalent in a beam's eye view. The gas-electron signals, collected on the strips and pad arrays of each PPIC, were amplified and processed with a continuous charge.integration mode. The detector was tested with 190-MeV raster-scan-mode beams that were provided by the Proton Therapy Facility at Samsung Medical Center, Seoul, South Korea. The detector responses of the PPICs for a 190-MeV raster-scan-mode proton beam agreed well with the dose data, measured using a 2D ionization chamber array (Octavius model, PTW). Furthermore, in this study it was confirmed that the detector simultaneously tracked the doses induced at the PPICs by the fast-oscillating beam, with a scanning speed of 2 m s-1. Thus, it is anticipated that the present detector, composed of thin PPICs and operating in charge.integration mode, will allow medical scientists to perform reliable fast dose-verification measurements for typical dynamic mode therapeutic beams.