• Journal of The Korea Institute of Healthcare Architecture
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• v.24 no.4
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• pp.69-87
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• 2018

Purpose: This study has been started with the awareness that light and color are the main visual sensors of the multi-sensory stimulation environment to achieve the therapeutic environment for demented elderly. The purpose of this study therefore is for clarifying the application characteristics of therapeutic light and color for dementia care facilities. Methods: Internal and external literature reviews have been conducted for the investigation into a)disorders and visual system in demented elderly, b)therapeutic effects of light and color, c)heliotherapy, light therapy and color therapy to deduce the therapeutic characteristics of light and color for demented elderly, and finally into d)the application characteristics of it for dementia care facilities. Results: The application characteristics of the therapeutic light and color for dementia care facilities are classified into both qualitative and quantitative characteristics. Qualitative application characteristics of light represented using of daylight, using of lighting approximate to daylight, expansion of iluminance level, equality in iluminance Level, reduction of shadow, and as well as exclusion of blare. Quantitative application characteristics of it represented iluminance level, color temperature and color rendering index prescribed in international lighting standards. Qualitative application characteristics of color represented non-monochromatic color, color contrast, long wavelength of yellow-red colors, exclusion of short wavelength of blue colors and patterns, and as well as different colors for idenfication. Quantitative application characteristics of it represented kontrast(K) prescribed in DIN32975:2009 and light reflectance value(LRV) prescribed in BS8300:2009. Implications: To form dementia care facilities as therapeutic environment both qualitative and quantitative application characteristics of therapeutic light and color in dementia care facilities are needed.

• Journal of Korean Medical classics
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• v.33 no.1
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• pp.1-16
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• 2020

Objectives : This study aims to organize the genealogy of the Ministerial Fire Theory in relation to Wangbing's Dragon Fire discourse through examining how Wang's Dragon Fire content first mentioned in the annotation of 『Suwen』 was included into the discourse of the Ministerial Fire Theory in explaining the concept of Ministerial Fire and its therapeutic application. Methods :First to examine the inclusion and application of the Dragon Fire concept into the Ministerial Fire Theory, Zhudanxi's theory and critiques on him were studied. Next the concept of Dragon Fire within the Ministerial Fire Theory was analyzed, followed by comparison between generations of doctors's therapeutic application of Ministerial Fire and Wangbing's Dragon Fire application. Conclusions & Results : Wangbing's dragon fire concept held an important position in discussing its characteristic as fire within water, which was adopted and differentiated by later doctors in aspects of pathology, deficiency and excessiveness, influenced by various theoretical elements of later periods. In the midst of expansion of the concept from combination of dragon fire and ministerial fire, the therapeutic aspect of it was maintained from Wangbing's original mentioning. This tendency manifested in either awkward combination of Wang's therapeutic methods and the new theory or modification of Wangbing's methods.

• Nuclear Medicine and Molecular Imaging
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• v.40 no.2
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• pp.58-65
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• 2006

Since the development of sophisticated molecular carriers such as octereotides for peptide receptor targeting and monoclonal antibodies against various antigens associated with specific tumor types, radionuclide therapy (RNT) employing open sources of therapeutic agents is promising modality for treatment of tumors. furthermore, the emerging of new therapeutic regimes and new approaches for tumor treatment using radionuclide are anticipated in near future. In targeted radiotherapy using peptides and other receptor based tarrier molecules, the use of radionuclide with high specific activity in formulating the radiopharmaceutical is essential in order to deliver sufficient number of radionuclides to the target site without saturating the target. In order to develop effective radiopharmaceuticals for therapeutic applications, it is crucial to carefully consider the choice of appropriate radionuclides as well as the tarrier moiety with suitable pharmacokinetic properties that could result in good in vivo localization and desired excretion. Up to date, only a limited number of radionuclides have been applied in radiopharmaceutical development due to the constraints in compliance with their physical half-life, decay characteristics, cost and availability in therapeutic applications. In this review article, we intend to provide with the improved understanding of the factors of importance of appropriate radionuclide for therapy with respect to their physical properties and therapeutic applications.

• Biotechnology and Bioprocess Engineering:BBE
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• v.5 no.4
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• pp.219-226
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• 2000

The application of recombinant DNA technology to restructure metabolic net-work can change metabolite and protein products by altering the biosynthetic pathways in an organism. Although some success has been achieved, a more detailed and thorough investigation of this approach is certainly warranted since it is clear that such methods hold great potential based on the encouraging results obtained so far. In last decade, there have been tremendous advances in the field of glycobiology and the stage has been set for the biotechnological production of glycoproteins for therapeutic use. Today glycoproteins are one of the most important groups of pharmaceutical products. In this study the attempt was made to focus on identifying technologies that may have general application for modifying glycosylation pathway of the yeast cells in order to produce glycoproteins of therapeutic use. The carbohydrates of therapeutic recombinant glycoproteins play very important roles in determining their pharmacokinetic properties. A number of biological interactions and biological functions mediated by glycans are also being targeted for therapeutic manipulation in vivo. For a commercially viable production of therapeutic glycoproteins a metabolic engineering of a host cell is yet to be established.

• Korean Journal of Biological Psychiatry
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• v.5 no.1
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• pp.17-33
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• 1998

Advances in molecular biology contribute to the understanding genetic mechanism of psychiatric disorders. They have renewed hope for the discovery of disease relevant gene. However, the results somewhat confused. And we will wait for a long time for the application of gene therapy in schizophreniar. Fortunately we could classified the schizophrenia with genotypes of dopamine and serotonin receptors. It is expected that this genetic classification could provide key strategy for the therapeutic application in biological treatment for schizophrenia. The purpose of this article is to call attention of the institute participants to linkage, association, mRNA expression, genotypic classification and to the need for more systemic research. The author summarized the modified methods which were done in his laboratory in appendix.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.11 no.2
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• pp.161-178
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• 2000

The author reviewed history and development of variable approaches of play psychotherapy. To understand basic concepts and practical factors of play, the functions of play behavior and it's clinical application were summarized. As major therapeutic approaches, both theoretical concepts and practical techniques of psychoanalytic approach and those of nondirective approach were presented. For clinician it is important to know developmental theories which can be applied to various therapeutic technics and to apply these theories to play therapy situations. So, to know the developmental approach in play psychotherapy, play as a developmental process, its' therapeutic application, play in the perspective of cognitive development and the therapeutic process of play psychotherapy were reviewed. With the knowledge of developmental concept therapists can increase their abilities to prescribe an appropriate type of play therapy.

• PNF and Movement
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• v.21 no.1
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• pp.129-137
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• 2023

Purpose: The physical therapy diagnosis process requires high-level background knowledge, the ability to obtain added information from patients, accurate examination skills, and a framework for transforming thoughts into a diagnostic decision. Thus, the physical therapy diagnostic process is highly complicated and difficult work. To function as autonomous professionals, physical therapists must develop effective clinical diagnosis skills. As such, mobile application aids can help with accurate and scientific diagnoses. Therefore, this study aims to develop and evaluate the usability of a mobile application for physical therapy diagnoses. Methods: In this study, a diagnostic application was developed using App Inventor, the development environment was the Chrome web browser for Windows 10, and the mobile application was run on a Google Pixel 5. The developed application was evaluated for usability by 20 physical therapists with more than 5 years of clinical experience in the musculoskeletal physical therapy field, and a usability evaluation was conducted using a 5-point Likert scale for accuracy, convenience, satisfaction, and usability. The collected Likert scores were converted into percentages and analyzed as descriptive statistics. Results: The graphical user interface consisted of an initial screen with program guidance, 18 screens presenting the algorithm, and 12 screens presenting the estimated diagnosis based on the algorithm. As such, the usability evaluation of the developed application was as follows: accuracy 100%, convenience 90%, satisfaction 91%, and usability 88%. Conclusion: The newly developed mobile application for physical therapeutic diagnoses has a high accuracy, and it will aid in building an easy and reliable physical therapy diagnosis system.

• KIEAE Journal
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• v.4 no.2
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• pp.57-64
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• 2004

Apartments recently built have been strategically designed in many ways, and one of the most striking aspects is to utilize the idea of environmental friendliness and the application to the living environment. Especially, the number of environmentally friendly apartments that concern the health of residents have been increasing and their landscape is notably differentiated. The purpose of this research study was to examine the landscape of the environmentally friendly apartments that have been built in the past five years, and to assess its features in the aspects of therapeutic garden. Based upon the review of previous studies, this study constructed a checklist that was used to evaluate the planning components of the landscape during site visits. This study found that overall landscape selected in the study was well-planned. However, it was suggested that more features of therapeutic garden such as vegetation area which both encourages interaction with residents and produces therapeutic benefits be adopted in planning the advanced therapeutic garden of environmentally friendly apartments.

• The Journal of Korean Academy of Orthopedic Manual Physical Therapy
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• v.7 no.1
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• pp.51-66
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• 2001

Objective: The purpose of study was to compare physical therapy duration in relation tohealth care organization system in patients with low back pain. Subjects: Subjects of this study were 759 patients who are receiving physical therapy at 56 health care organization. Methods: Data were collected by questionnaire that had been completed by patients and physical therapist for two months. Physical therapy procedures consisted of modality application, manual therapy, active therapeutic exercise, and patient education. Physical therapy session duration was investigated for each physical therapy procedure. Data were analyzed in relation to the university hospital, hospital, and clinic. Results: The mean age of subjects was $42.84{\pm}15.46$. There were no significant differences in age among three groups. The number of patients diagnosed with herniated disc were 244(32.15%) and with mechanical low back pain was 187(24.64%). The mean treatment duration per day was 53.22 minutes, and the longest treatment duration was 61.28 minutes at the university hospitals (p<0.001). The mean modality application duration was 42.17 minutes, and the longest application duration was 46.26 minutes at the university hospitals (p<0.001). The mean duration for manual therapy was 5.11 minutes, and the longest treatment duration was 5.97 minutes at clinics. The mean duration for active therapeutic exercise was 4.16 minutes. It was 7.60 minutes at the university hospitals, and 2.48 minutes at clinics. There was a significant difference in active therapeutic exercise duration between university hospitals and clinics(p<0.001). For modalities, hot packs(89.33%) and interferential current therapy(60.87%) were mostly applied. For manual therapy, Soft tissue mobilization(32.93%) and manipulation(14.10%) were mostly applied. In general, treatment application duration was longer at University hospital (p<0.05). For therapeutic exercise, exercise without equipment(18.84%) and muscle strengthening (16.73%) were mostly performed. The longest treatment duration for therapeutic exercise was 7.60 minutes at the university hospital(p<0.05). Conclusion: physical therapy session duration for low back pain was 53.22 minutes. Modality application constitutes 79%, manual therapy 10%, active therapeutic exercise 8% of total treatment duration. It is concluded that patients do not participate actively in treatment procedures.

• The Journal of Korean Society for Radiation Therapy
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• v.3 no.1
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• pp.45-50
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• 1989

Wedge filter are used in high energy radiation therapy to obtain uniform isodose lines at small volume tumor and irregular body surface. The aim of this study is not only to describe the method of construction and setting of semi-universal wedge filter for $^{60}Co$ radiation therapy but also to get the optimum treatment planning by clinical application of wedge filter.