• 한국지반신소재학회논문집
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• 제18권2호
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• pp.45-54
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• 2019

본 연구에서는 원지반의 상대밀도와 세립분 함유율의 조건에 따른 말뚝의 인발거동 특성 규명을 위하여, 유한요소해석을 수행하였다. 수치해석에서는 말뚝과 지반 경계에서의 전단거동을 원활히 모사하기 위해서 경계요소와 경계면 강도감소계수($R_{inter}$)를 부여하였으며, 그 결과를 기존의 실험적 연구결과(You et al., 2018)와 비교함으로써 본 수치해석 방법의 신뢰성을 검증하였고, 말뚝-지반 경계면에서의 변형 특성과 함께 경계요소에 대한 $R_{inter}$값의 결정방법을 제시하였다. 해석 결과, 본 연구에서 적용된 해석모델을 이용한 수치해석은 말뚝의 인발모형실험에 의한 말뚝과 지반의 경계면 특성을 적절하게 모사하였다. 또한 제시된 $R_{inter}$의 적용에 있어서, 반드시 지반의 상대밀도와 세립분 함유율 조건을 고려해야 할 필요가 있음을 확인하였다.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제28권4호
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• pp.365-370
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• 2006

Viral, bacterial and fungal infections can be transmitted via allografts such as bone, skin, cornea and cardiovascular tissues. Allogenic bone grafts have possibility of transmission of hepatitis C, human immunodeficiency virus (HIV-1), human T-Cell leukaemia virus (HTLV), tuberculosis and other bacterias. The tissue bank should have a policy for obtaining information from the patient's medical report as to whether the donor had risk factors for infectious diseases. Over the past several years, improvements in donor screening criteria, such as excluding potential donor with "high risk" for HIV-1 and hepatitis infection, and donor blood testing result in the reduction of transmission of these diseases. During tissue processing, many allografts are exposed to antibiotics, disinfectants and terminal sterilization such as irradiation, which further reduce or remove the risk of transmitting diseases. Because the effectiveness of some tissue grafts such as, fresh frozen osteochondral grafts, depends on cellular viability, not all can be subjected to sterilization and processing steps and, therefore, the risk of transmission of infectious disease remains. This article is review of the transmission of considering infectious disease in allogenic bone transplantation and the processing steps of reducing the risk. The risk of viral transmission in allografts can be reduced in several standards. The most important are donor-screening tests and the removal of blood and soft tissues by processing steps under the aseptic environment. In conclusion, final sterilizations including the irradiation, can be establish the safety of allografts.

• 한국전문물리치료학회지
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• 제30권4호
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• pp.288-305
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• 2023

Background: The compression therapy, which is the standard treatment for lymphedema patients, may be difficult to implement and contraindicated to some patients depending on their health condition. Objects: The purpose of this study is to investigate whether kinesiology taping (KT) can be used effectively and safely in the management of lymphedema as an alternative treatment through systematic review and meta-analysis. Methods: In February 2023, the literature was systematically collected through eight search engines with a combination of terms, 'lymphedema' and 'kinesiology taping.' We qualitatively analyzed the differences and safety of KT methods, and quantitatively meta-analyzed the effects of volume reduction in edema, range of motion (ROM), and pain improvement using Review Manager ver. 5. 4. To assess the risk of bias in the randomized controlled trial (RCT) studies, Risk of Bias was used. Results: A total of 616 articles searched and 20 studies were selected, including 12 RCTs and eight case studies. KT intervention could not replace multilayer compression bandage (MLB), but it demonstrated similar or better results compared to compression garment (CG), with reduced pain and improved intervention comfort. Studies reported skin adverse events ranging from 2.5% to 20.68%, with a total adverse event incidence of 7.7%. There was no significant difference in the application method of KT. As a result of the meta-analysis from the 8 RCTs, the KT intervention showed a mean difference (MD) of -7.18 with a 95% confidence interval (CI) [-12.64 to -1.72] in the volume change of lymphedema, while the pain difference was MD 0.82 with CI 95% [0.50 to 1.15], in comparison to the MLB and CG intervention. Conclusion: KT therapy led to a reduction in edema size, volume, pain, and improved ROM and quality of life. KT may be a viable option for lymphedema patients who have trouble applying traditional compression therapies.

• 한국지반공학회논문집
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• 제16권1호
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• pp.107-116
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• 2000

4개 현장에 실물크기의 강관말뚝과 PC 및 PHC 말뚝의 축방향에 대한 지지거동을 알아보기 위하여, 강관말뚝에 스트레인게이지를 부착하고 항타시 계측기 손상여부를 조사하면서 동재하시험을 수행하였다. 아울러 동일한 말뚝에 대하여 2일과 7일 경과후에 정재하시험을 실시하여 하중-침하량 거동과 주면 및 선단지지력을 분리 측정하였다. 그 결과, CAPWAP 해석에 Davisson방법을 적용하여 구한 강관말뚝의 허용지지력은 정재하시험에서 구한 허용지지력 보다 약 2~33%정도 크게 나타났다. 그리고 정재하시험 결과에서 구한 산술평균한 허용지지력은 CAPWAP해석에서 Davisson's offset방법으로 구한 허용지지력보다 극한지지력에 FS=2.5를 적용하여 구한 허용지지력에 더 근접하는 경향을 보였다. 또한, 단위면적당 주면지지력은 깊이가 증가함에 따라 증가하였고, 말뚝선단부 1~2m 이내에서 발휘되는 비율이 상당히 큰 것으로 나타났다.

• Archives of Plastic Surgery
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• 제40권2호
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• pp.91-96
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• 2013

Background A thinned anterolateral thigh (ALT) flap is often harvested to achieve optimal skin resurfacing. Several techniques have been described to thin an ALT flap including an adipocutaneous flap, an adipofascial flap and delayed debulking. Methods By systematically reviewing all of the available literature in English and French, the present manuscript attempts to identify the common surgical indications, complications and donor site morbidity of the adipofascial variant of the ALT flap. The studies were identified by performing a systematic search on Medline, Ovid, EMBASE, the Cochrane Database of Systematic Reviews, Current Contents, PubMed, Google, and Google Scholar. Results The study selection process was adapted from the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement, and 15 articles were identified using the study inclusion criteria. These articles were then reviewed for author name(s), year of publication, flap dimensions and thickness following defatting, perforator type, type of transfer, complications, thinning technique, number of cases with a particular area of application and donor site morbidity. Conclusions The adipofascial variant of the ALT flap provides tissue to fill large defects and improve pliability. Its strong and safe blood supply permits adequate immediate or delayed debulking without vascular complications. The presence of the deep fascia makes it possible to prevent sagging by suspending and fixing the flap for functional reconstructive purposes (e.g., the intraoral cavity). Donor site morbidity is minimal, and thigh deformities can be reduced through immediate direct closure or liposuction and direct closure. A safe blood supply was confirmed by the rate of secondary flap debulking.

• KSBB Journal
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• 제17권2호
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• pp.176-181
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• 2002

Astaxanthin (3,3＇-dihydroxy-${\beta}$, ${\beta}$-carotene-4-4＇-dione), a natural pigment of pink to red color, is widely distributed in nature particularly in the skin layer of salmonoids and the crust of shrimp, lobster, etc. Recently, it was produced from the yeast culture of Phaffia rhodozyma. Because of its high thermal stability and antioxidant functionality, its applications can be extended into food, cosmetics, and pharmaceutical ingredient beyond the traditional feed additive. Because of its very high lipophilicity, astaxanthin has been extracted traditionally by strong organic solvents such as chloroform, petroleum ether, acetone, etc. In this study, we developed a surfactant-based solubillization system for astaxanthin, and used it to extract astaxanthin from disrupted yeast cells. Among Tween 20, Triton X-100 and SDS, Tween 20 was identified as the most suitable surfactant in terms of extraction capacity and safety. The ethylene oxide group of Tween 20 was identified as the most significant factor to increase the HLB value that determined the extraction capacity. The effects of micelle formation condition, such as the molar ratio of astaxanthin and Tween 20, pH, and ionic strength were also investigated. pH and ionic strength showed no significant effects. The optimal molar ratio between astaxanthin and Tween 20 was 1 : 12. Antioxidant activity of astaxanthin was higher than ${\beta}$-carotene and ${\alpha}$-tocopherol. Astaxanthin in the crude extract from the yeast cell was more resistant to air and/or light degradation than pure astaxanthin, probably because of the presence of other carotenoids and lipids.

• 한국항공우주학회지
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• 제31권5호
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• pp.110-116
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• 2003

항공기 기술의 발전에 따라 기체 경량화는 성능에 큰 영향을 미치는 요소로 대두되었으며, 비행 중 도는 지상 계류 중 우박에 의한 표면 손상 문제가 중요한 설계 인자로 부각되었다. 우박은 항공기 운용 안정성 및 비용 면에서 심각한 피해를 입히는 경우가 많다. 대부분의 군용, 상용 항공기의 외부 구조 특히 레이돔, 캐노피 등 전방 부분과 주익, 미익의 앞전 부분은 쉽게 손상을 입는 부분임에도 불구하고, 이에 관한 연구는 활발하지 못했다. 이에 관한 일부 연구도 복합재에 집중되어 왔으며, 금속재에 관한 연구는 미미한 편이다. 본 연구에서는 상용 비선형 동적 수치 해석 코드인 LS-DYNA를 이용하여 ice 재질의 충돌 거동과 박판 알루미늄의 충돌 영향성을 분석하였다. 해석 방법은 유사 실험 자료를 이용하여 검증하였고, 주요 결과를 도표화하여 활용 및 응용 방안을 모색하였다.

• Journal of Preventive Medicine and Public Health
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• 제45권6호
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• pp.344-352
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• 2012

Mercury is a toxic and non-essential metal in the human body. Mercury is ubiquitously distributed in the environment, present in natural products, and exists extensively in items encountered in daily life. There are three forms of mercury, i.e., elemental (or metallic) mercury, inorganic mercury compounds, and organic mercury compounds. This review examines the toxicity of elemental mercury and inorganic mercury compounds. Inorganic mercury compounds are water soluble with a bioavailability of 7% to 15% after ingestion; they are also irritants and cause gastrointestinal symptoms. Upon entering the body, inorganic mercury compounds are accumulated mainly in the kidneys and produce kidney damage. In contrast, human exposure to elemental mercury is mainly by inhalation, followed by rapid absorption and distribution in all major organs. Elemental mercury from ingestion is poorly absorbed with a bioavailability of less than 0.01%. The primary target organs of elemental mercury are the brain and kidney. Elemental mercury is lipid soluble and can cross the blood-brain barrier, while inorganic mercury compounds are not lipid soluble, rendering them unable to cross the blood-brain barrier. Elemental mercury may also enter the brain from the nasal cavity through the olfactory pathway. The blood mercury is a useful biomarker after short-term and high-level exposure, whereas the urine mercury is the ideal biomarker for long-term exposure to both elemental and inorganic mercury, and also as a good indicator of body burden. This review discusses the common sources of mercury exposure, skin lightening products containing mercury and mercury release from dental amalgam filling, two issues that happen in daily life, bear significant public health importance, and yet undergo extensive debate on their safety.

• Parasites, Hosts and Diseases
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• 제51권5호
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• pp.545-549
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• 2013

A 12-year-old spayed female mixed-bred dog presented with nasal bleeding of 2 days duration and a skin nodule in the left flank. No abnormalities were found in coagulation profiles and blood pressure. Cytological evaluation of the nodule revealed numerous characteristic round organisms having a nucleus and a bar within macrophages and in the background, consistent with leishmaniasis. In vitro culture was unsuccessful but PCR of the nodular aspirate identified the organisms as Leishmania infantum, and the final diagnosis was canine leishmaniasis. No history of travel to endemic countries was noted. Because the dog had received a blood transfusion 2 years before the illness, serological screening tests were performed in all donor dogs of the commercial blood bank using the commercial Leishmania ELISA test kit, and there were no positive results. Additional 113 dogs with hyperglobulinemia from Seoul were also screened with the same kits but no positive results were obtained. To the best of the author's knowledge this is the first autochthonous case of canine leishmaniasis in Korea.

• 한국추진공학회지
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• 제4권3호
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• pp.29-37
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• 2000

풍력 터빈회전날개의 설계시 구조적 형상을 결정하는 예비설계 단계에서 종전에는 여러 가지 다양한 경우의 설계를 수행하여 이중 적합한 경우를 채택하는 시행착오 방법은 많은 설계시간을 요하였으나, 본 연구에서는 이 같은 설계시의 비효율적 요소를 배제하고자 적층판 이론을 기초로 한 설계 프로그램을 이용하는 설계기법을 계발함으로서 설계절차를 개선하였다. 개선된 설계절차에 따라 국제표준 설계규격 IEC1400-1에서 규정한 각 경우의 하중해석과 응력, 변형율 및 변형한계를 설정한 후, 단순화한 복합재 회전날개 구조에 혼합법칙과 주 응력 설계기법을 이용하여 복합재 구조의 형상을 정하였다. 설계된 구조는 본 연구를 통해 개발된 적층판 이론을 기초로 한 프로그램을 이용하여 강도 및 좌굴에 대한 구조의 안정성을 확인하여 상세설계 과정시 소요되는 시간을 최소화하였다. 설계된 구조는 표피 등을 고려하여 수정 설계한 후 유한요소법을 이용하여 응력, 변형율, 변위, 고유 진동수, 좌굴안정성, 피로수명 등을 해석하여 국제 표준규격의 만족 여부를 확인하였다.