• Title/Summary/Keyword: The skin safety

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A Study on Strength Reduction Factor of Pile-soil Interface for Evaluation of Pile Pullout Resistance by Soil Condition (지반조건에 따른 말뚝의 인발저항 평가를 위한 말뚝-지반 경계면 강도감소계수 고찰)

  • You, Seung-Kyong;Shin, Heesoo;Lee, Kwang-Wu;Park, Jeong-Jun;Choi, Choong-Lak;Hong, Gigwon
    • Journal of the Korean Geosynthetics Society
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    • v.18 no.2
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    • pp.45-54
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    • 2019
  • This paper describes the results of finite element analysis (FEA), in order to investigate a characteristics of pile pullout behavior according to the conditions of the relative density and fines content in original ground. In the FEA, a boundary elements and strength reduction factors ($R_{inter}$) on pile-soil interface were applied to simulate appropriately the shear behavior at the pile-soil interface, and then the reliability of numerical analysis method was verified by comparison of FEA results and previous experimental research(You et al., 2018). In addition, a the deformation characteristics at the pile-soil interface and determination method of $R_{inter}$ value was laid out. The results showed that the FEA, based on the analytical model applied in this study simulates appropriately the characteristics of the pile-soil interface by pullout model test of pile. In order to apply the suggested $R_{inter}$ value, it is necessary to consider the condition of the relative density and the fines content in ground.

THE REVIEW OF TRANSMISSION OF INFECTIOUS DISEASE IN HUMAN TISSUE TRANSPLANTATION: PART I ALLOGENIC BONE (동종조직이식술 시 전염성질환의 이환가능성에 대한 고찰 I : 동종골조직)

  • Lee, Eun-Young;Kim, Kyoung-Won;Um, In-Woong
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.28 no.4
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    • pp.365-370
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    • 2006
  • Viral, bacterial and fungal infections can be transmitted via allografts such as bone, skin, cornea and cardiovascular tissues. Allogenic bone grafts have possibility of transmission of hepatitis C, human immunodeficiency virus (HIV-1), human T-Cell leukaemia virus (HTLV), tuberculosis and other bacterias. The tissue bank should have a policy for obtaining information from the patient's medical report as to whether the donor had risk factors for infectious diseases. Over the past several years, improvements in donor screening criteria, such as excluding potential donor with "high risk" for HIV-1 and hepatitis infection, and donor blood testing result in the reduction of transmission of these diseases. During tissue processing, many allografts are exposed to antibiotics, disinfectants and terminal sterilization such as irradiation, which further reduce or remove the risk of transmitting diseases. Because the effectiveness of some tissue grafts such as, fresh frozen osteochondral grafts, depends on cellular viability, not all can be subjected to sterilization and processing steps and, therefore, the risk of transmission of infectious disease remains. This article is review of the transmission of considering infectious disease in allogenic bone transplantation and the processing steps of reducing the risk. The risk of viral transmission in allografts can be reduced in several standards. The most important are donor-screening tests and the removal of blood and soft tissues by processing steps under the aseptic environment. In conclusion, final sterilizations including the irradiation, can be establish the safety of allografts.

A Systematic Review of Kinesiology Taping in Patients With Lymphedema

  • Jaehee Yang;Eun Jin Lim
    • Physical Therapy Korea
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    • v.30 no.4
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    • pp.288-305
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    • 2023
  • Background: The compression therapy, which is the standard treatment for lymphedema patients, may be difficult to implement and contraindicated to some patients depending on their health condition. Objects: The purpose of this study is to investigate whether kinesiology taping (KT) can be used effectively and safely in the management of lymphedema as an alternative treatment through systematic review and meta-analysis. Methods: In February 2023, the literature was systematically collected through eight search engines with a combination of terms, 'lymphedema' and 'kinesiology taping.' We qualitatively analyzed the differences and safety of KT methods, and quantitatively meta-analyzed the effects of volume reduction in edema, range of motion (ROM), and pain improvement using Review Manager ver. 5. 4. To assess the risk of bias in the randomized controlled trial (RCT) studies, Risk of Bias was used. Results: A total of 616 articles searched and 20 studies were selected, including 12 RCTs and eight case studies. KT intervention could not replace multilayer compression bandage (MLB), but it demonstrated similar or better results compared to compression garment (CG), with reduced pain and improved intervention comfort. Studies reported skin adverse events ranging from 2.5% to 20.68%, with a total adverse event incidence of 7.7%. There was no significant difference in the application method of KT. As a result of the meta-analysis from the 8 RCTs, the KT intervention showed a mean difference (MD) of -7.18 with a 95% confidence interval (CI) [-12.64 to -1.72] in the volume change of lymphedema, while the pain difference was MD 0.82 with CI 95% [0.50 to 1.15], in comparison to the MLB and CG intervention. Conclusion: KT therapy led to a reduction in edema size, volume, pain, and improved ROM and quality of life. KT may be a viable option for lymphedema patients who have trouble applying traditional compression therapies.

The Behavior of Bearing Capacity for the Precast files (기성말뚝의 지지거동)

  • 박영호
    • Journal of the Korean Geotechnical Society
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    • v.16 no.1
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    • pp.107-116
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    • 2000
  • Dynamic and static load tests are conducted in four construction sites by using steel pipe piles(SPP) and concrete piles to compare differences of load bearing mechanism. Steel pipe piles are instrumented with electric strain gages and are subject to dynamic load tests during driving. The damage of strain gages attached is checked simultaneously. Static load test is also conducted on the same piles after two to seven days' elapse. Then load-settlement behavior and shaft and/or tip resistances are measured. As a result, the allowable bearing capacity calculated by the Davisson's offset method of CAPWAP analysis shows 2~33% larger than that of static load test. The average value of allowable bearing capacity of static load test is closer to the allowable capacity obtained at the safety factor of 2.5 applied on ultimate bearing capacity than to the one obtained from the Davisson's offset method. The analysis of strain gage readings shows that unit skin friction increases with depth. Furthermore, the friction mobilized around the 1~2m above the pile tip considerably contributes to the total shaft resistance.

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Adipofascial Anterolateral Thigh Flap Safety: Applications and Complications

  • Agostini, Tommaso;Lo Russo, Giulia;Zhang, Yi Xin;Spinelli, Giuseppe;Lazzeri, Davide
    • Archives of Plastic Surgery
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    • v.40 no.2
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    • pp.91-96
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    • 2013
  • Background A thinned anterolateral thigh (ALT) flap is often harvested to achieve optimal skin resurfacing. Several techniques have been described to thin an ALT flap including an adipocutaneous flap, an adipofascial flap and delayed debulking. Methods By systematically reviewing all of the available literature in English and French, the present manuscript attempts to identify the common surgical indications, complications and donor site morbidity of the adipofascial variant of the ALT flap. The studies were identified by performing a systematic search on Medline, Ovid, EMBASE, the Cochrane Database of Systematic Reviews, Current Contents, PubMed, Google, and Google Scholar. Results The study selection process was adapted from the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement, and 15 articles were identified using the study inclusion criteria. These articles were then reviewed for author name(s), year of publication, flap dimensions and thickness following defatting, perforator type, type of transfer, complications, thinning technique, number of cases with a particular area of application and donor site morbidity. Conclusions The adipofascial variant of the ALT flap provides tissue to fill large defects and improve pliability. Its strong and safe blood supply permits adequate immediate or delayed debulking without vascular complications. The presence of the deep fascia makes it possible to prevent sagging by suspending and fixing the flap for functional reconstructive purposes (e.g., the intraoral cavity). Donor site morbidity is minimal, and thigh deformities can be reduced through immediate direct closure or liposuction and direct closure. A safe blood supply was confirmed by the rate of secondary flap debulking.

Solubillzation and Extraction Of Antioxidant Astaxanthin by Micelle Formation from Phaffia rhodozyma Cell Homogenate (Phaffia rhodozyma 세포파쇄액으로부터 항산화제 Astaxanthin의 미셀 형성을 통한 가용화 및 추출)

  • Kim, Young-Beom;Ryu, Kang;Lim, Gio-Bin;Lee, Eun-Kyu
    • KSBB Journal
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    • v.17 no.2
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    • pp.176-181
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    • 2002
  • Astaxanthin (3,3'-dihydroxy-${\beta}$, ${\beta}$-carotene-4-4'-dione), a natural pigment of pink to red color, is widely distributed in nature particularly in the skin layer of salmonoids and the crust of shrimp, lobster, etc. Recently, it was produced from the yeast culture of Phaffia rhodozyma. Because of its high thermal stability and antioxidant functionality, its applications can be extended into food, cosmetics, and pharmaceutical ingredient beyond the traditional feed additive. Because of its very high lipophilicity, astaxanthin has been extracted traditionally by strong organic solvents such as chloroform, petroleum ether, acetone, etc. In this study, we developed a surfactant-based solubillization system for astaxanthin, and used it to extract astaxanthin from disrupted yeast cells. Among Tween 20, Triton X-100 and SDS, Tween 20 was identified as the most suitable surfactant in terms of extraction capacity and safety. The ethylene oxide group of Tween 20 was identified as the most significant factor to increase the HLB value that determined the extraction capacity. The effects of micelle formation condition, such as the molar ratio of astaxanthin and Tween 20, pH, and ionic strength were also investigated. pH and ionic strength showed no significant effects. The optimal molar ratio between astaxanthin and Tween 20 was 1 : 12. Antioxidant activity of astaxanthin was higher than ${\beta}$-carotene and ${\alpha}$-tocopherol. Astaxanthin in the crude extract from the yeast cell was more resistant to air and/or light degradation than pure astaxanthin, probably because of the presence of other carotenoids and lipids.

Investigation of Ice Impacts on Aluminum Skin Structure (알루미늄 표피 구조의 Ice 충돌 특성에 관한 연구)

  • Park, Gyu Cheol;Myeong, No Sin
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.31 no.5
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    • pp.110-116
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    • 2003
  • With the growth of aircraft performance and needs for light aircraft, the problems associated with hail impacts on aircraft during flights and grounding become and important issue. These hail encounters can cause severe damages to aircraft and result in major concerns in safety and cost. Since nearly all external components of the commercial and military aircraft-in particular, the nose section and the leading edge of the wing and tail-are subject to damages, much effort has been put into understanding of this problem. However, most of the previous studies have focused on the composite components and few results have been reported for the metallic components. In this paper, we study the ice impacts on the aluminum component with the finite element analysis method utilizing commercial non-linear dynamics solver LS-DYNA. The results are compared with the experimental data and a simple measure of the ice impact effects is proposed.

Human Exposure and Health Effects of Inorganic and Elemental Mercury

  • Park, Jung-Duck;Zheng, Wei
    • Journal of Preventive Medicine and Public Health
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    • v.45 no.6
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    • pp.344-352
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    • 2012
  • Mercury is a toxic and non-essential metal in the human body. Mercury is ubiquitously distributed in the environment, present in natural products, and exists extensively in items encountered in daily life. There are three forms of mercury, i.e., elemental (or metallic) mercury, inorganic mercury compounds, and organic mercury compounds. This review examines the toxicity of elemental mercury and inorganic mercury compounds. Inorganic mercury compounds are water soluble with a bioavailability of 7% to 15% after ingestion; they are also irritants and cause gastrointestinal symptoms. Upon entering the body, inorganic mercury compounds are accumulated mainly in the kidneys and produce kidney damage. In contrast, human exposure to elemental mercury is mainly by inhalation, followed by rapid absorption and distribution in all major organs. Elemental mercury from ingestion is poorly absorbed with a bioavailability of less than 0.01%. The primary target organs of elemental mercury are the brain and kidney. Elemental mercury is lipid soluble and can cross the blood-brain barrier, while inorganic mercury compounds are not lipid soluble, rendering them unable to cross the blood-brain barrier. Elemental mercury may also enter the brain from the nasal cavity through the olfactory pathway. The blood mercury is a useful biomarker after short-term and high-level exposure, whereas the urine mercury is the ideal biomarker for long-term exposure to both elemental and inorganic mercury, and also as a good indicator of body burden. This review discusses the common sources of mercury exposure, skin lightening products containing mercury and mercury release from dental amalgam filling, two issues that happen in daily life, bear significant public health importance, and yet undergo extensive debate on their safety.

An Autochthonous Case of Canine Visceral Leishmaniasis in Korea

  • Bhang, Dong Ha;Choi, Ul Soo;Kim, Hyun Jeong;Cho, Kyoung-Oh;Shin, Sung-Shik;Youn, Hee-Jeong;Hwang, Cheol-Yong;Youn, Hwa-Young
    • Parasites, Hosts and Diseases
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    • v.51 no.5
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    • pp.545-549
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    • 2013
  • A 12-year-old spayed female mixed-bred dog presented with nasal bleeding of 2 days duration and a skin nodule in the left flank. No abnormalities were found in coagulation profiles and blood pressure. Cytological evaluation of the nodule revealed numerous characteristic round organisms having a nucleus and a bar within macrophages and in the background, consistent with leishmaniasis. In vitro culture was unsuccessful but PCR of the nodular aspirate identified the organisms as Leishmania infantum, and the final diagnosis was canine leishmaniasis. No history of travel to endemic countries was noted. Because the dog had received a blood transfusion 2 years before the illness, serological screening tests were performed in all donor dogs of the commercial blood bank using the commercial Leishmania ELISA test kit, and there were no positive results. Additional 113 dogs with hyperglobulinemia from Seoul were also screened with the same kits but no positive results were obtained. To the best of the author's knowledge this is the first autochthonous case of canine leishmaniasis in Korea.

Design Improvement on Wind Turbine Blade of Medium Scale HAWT by Considering IEC 1400-1 Specification (IEC1400-1 규격을 고려한 중형 수평축 풍력발전용 회전날개의 설계개선 연구)

  • 공창덕;정석훈;장병섭;방조혁
    • Journal of the Korean Society of Propulsion Engineers
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    • v.4 no.3
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    • pp.29-37
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    • 2000
  • Because the previous design procedure for the composite wind turbine blade structure using trial and error method takes long time, a improved design procedure by using the program based on classical laminate theory was proposed to reduce the inefficient element. According to the improved design procedure, limitation of strains, stresses and displacements specified by international standard specification IEC1400-1 for the composite wind turbine blade were applied to sizing the structural configuration by using the rule of mixture and the principal stress design technique with a simplified turbine blade. Structural safety for strength and buckling stability was confirmed by the developed analysis program based on the laminate theory to minimize the design procedure. After modifying the preliminary design result with additional structural components such as skin, foam sandwich and mounting joints, stresses, strains, displacements, natural frequency, buckling load and fatigue life were analyzed by the finite element method. Finally these results were confirmed by comparing with IEC1400-1 specification.

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