• BMB Reports
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• v.28 no.6
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• pp.477-483
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• 1995

The recombinant human interferon alpha 2a ($rhIFN-{\alpha}2a$), expressed in Saccharomyces cerevtsiae, was purified from insoluble aggregates. The inclusion body of $rhIFN-{\alpha}$ was solubilized by guanidine salt in the presence of disulfide reducing agent. The refolding of denatured $rhIFN-{\alpha}2a$ was achieved by simple dilution. The authentic interferon alpha, which has two correctly matched disulfide bonds, was seperated from incompletely oxidized $IFN-{\alpha}$ and dimeric $IFN-{\alpha}$ by use of a CM-Sepharose column, followed by size exclusion columns at two different pH conditions. The purified protein has been subjected to detailed physicochemical characterization including sequence determination. Unlike other $rhIFN-{\alpha}2a$ from E. coli reported, the $rhIFN-{\alpha}2a$ from S. cerevisiae has no methionine residue at its N-terminus originating from the start codon, ATG. The pI of the protein was determined to be 6.05 with a single band in the pI gel, which demonstrated that the purified $rhIFN-{\alpha}$ was homogeneous. The structural study using circular dichroism showed that the protein retains its three dimensional structure in the wide range of pH conditions between pH 3 and 9, and only minor strucural deformation was observed at pH 1.0.

• Journal of the Korean Society of Clothing and Textiles
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• v.43 no.2
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• pp.204-214
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• 2019

A CAD program has recently been introduced that can be directly developed into a three-dimensional human body shape and made into a pattern. It is possible to fabricate a bra that reflects the volume and surface area of the breast; however, it still needs to be verified. This study investigates the average size and shape of 20 big-breasted women and designs a brassiere pattern for women with large breasts using a 3D Flattening function of OptiTex PDS v15.6. In addition, the study verifies the reliability of the proposed method compared to a conventional brassiere pattern. The study results are as follows. First, the three dimensional measurement values were smaller than the direct measurement dimensions when the three dimension measurement dimensions of the subjects were compared with the direct measurement dimensions, the replica measurement dimensions and the three dimensional measurement dimensions. Second, the 3D flattening pattern reflects the actual shape, length, and area of the actual breast when comparing a brassiere pattern using a 3D shape and pattern reflecting the direct measurement.

• Journal of the Korean Home Economics Association
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• v.37 no.12 s.142
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• pp.59-67
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• 1999

This study analyzed firefighter's actual wearing condition of turnout gear The results are as fellows: 1. When a firefighter is employed, Korea applies only the minimum of firefighters stature and weight but America applies both the minimum and the maximum. The choice of size is highly related with stature more than chest circumference. 2. The satisfaction degree of thermal barrier is very low, 3%. They used rubber gloves rather than heatproof gloves. This is more serious in small country like 'up', 'myun' than in cities. For laundering, they used sprinkling method with firefighting hose. Firefigthers hoped that their clothes could be classified tv the seasons and fire places. 3. frefighter had high unsatisfaction with the movement of hands and leges in the aspect of movement adjustability, air permeability, weight, body temperature regulation, and breathing in the hygenic aspect, fire resistance, thermal resistance property, water proof, chemical reactivity and electrical conductivity. Thev were also unsatisfied with water proof boots and gloves. They were generally satisfied with helmets but firefighters over 90kg of weight were rather unsatisfied. 4. The satisfaction degree for physical fitness was very low and the items with which they were not satisfied depend on physical features. 5. To develop turnout gear, they wanted changes in design, material and size. Reflection tape need to be replaced with high quality products and they wanted the use of velcro and zipper in fastening system.

• Journal of the Korea Fashion and Costume Design Association
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• v.26 no.2
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• pp.101-114
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• 2024

Currently, in Korea, the number of handicapped children receiving inclusive education in general schools is expanding. In the inclusive education field, the most important tasks are personal needs support, such as toilet assistance, meal assitance, and support for wearing and taking off various assistive devices. A significant portion of the support work in the actual education field is related to clothing. Therefore, it is necessary to research and develop universal fashion designs for handicapped children at school where inclusive education is implemented. To achieve this aim, this study analyzed the concepts, principles and, characteristics of universal fashion design through theoretical research and established research principles. In this study, two fact-finding surveys were conducted. Next, a total of 10 universal fashion designs were proposed considering both the preceding survey results and the principles of universal fashion design Among them, the four designs that were considered most suitable were selected for universal fashion design through F.G.I (Focus Group Interview) analysis conducted by experts. The four selected designs were made by referring to the size framework based on the '6th Human Body Size Survey Report of Korea'. The completed experimental clothes were proposed as the final universal fashion design for handicapped children by conducting external evaluation through a virtual clothing system and real clothes.

• Transactions on Electrical and Electronic Materials
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• v.11 no.5
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• pp.226-229
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• 2010

Many methods exist that promote wound healing, including light therapy, which consists of light beams that assist the human body in treating and sterilizing wounds, as well as regenerating cells. Irradiation with specific wavelengths of either laser or LED light has been shown to induce beneficial proliferation of fibroblasts that, depending on the size of the wound, can be effective in promoting wound healing. The experiments in this study utilized 8 week old 250~300 g Male Sprague Dawley Rats (ILAR Code: NTacSam:SD) and included a non-irradiation group and a 525 nm green LED irradiation group (n of each group = 7). In experiments animals were allowed to rest for 24 hours after wounds had been excised, which was followed by non- irradiation or 525 nm green LED irradiation therapy one hour per day for 9 days. Immunohistochemical staining was conducted for cytokeratin in order to precisely measure the defect size. In addition, Masson's trichrome staining was utilized in order to compare levels of collagen between the 525 nm green LED irradiation group and the non-irradiation group. Animals exposed to 525 nm green LED irradiation (p<0.05) healed at a faster rate and had increased collagenosis compared with the non-irradiated control group. Thus, treatment with 525 nm green LED irradiation had a beneficial effect on wound healing and should be considered as a possible alternative to low power laser treatment.

• Fashion & Textile Research Journal
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• v.25 no.1
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• pp.52-61
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• 2023

This study aimed to present data for the development of a shoe which is suitable for plus-size men (BMI 25kg/m² or higher) and to analyze the characteristics of each type of foot. The results of the study are as follows. To assess foot shape in relation to weight gain, participants were categorized into normal weight, overweight, and obese weight groups, according to their BMI indexes. Those in the normal weight group exhibited a smaller value than the overweight or obese weight group in all items. As a result of the cluster analysis, by type of foot, of the obese men category, men were classified into four BMI index groups: members of the type 1 group had a BMI index of 157 (18.4% of total sample), while for type 2 the figure was 213 (25.0% of sample), for type 3 it was 259 (30.4%), and for type 4 it stood at 224 (26.3% of total sample). Those from the type 1 group had thin ankles with narrow toes and flattened sides. Type 2 group members had thick ankles with well-developed outer feet and thick sides. Those within the type 3 group had medium-thick ankles with narrow feet but wide inner feet. Finally, those in the type 4 group had feet with a slanted side, as well as thick ankles, wide feet, and flat sides. Among these categories, the type 3 group members indicated the highest distribution.

• Korean Journal of Human Ecology
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• v.14 no.2
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• pp.303-312
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• 2005

The purpose of this research is to analyze the lower part of dress forms with different sectional rotation-angles ($e.g.\;9^{\circ},\;15^{\circ},\;30^{\circ},\;45^{\circ}$) using three-dimensional measurement system and to investigate measurement properties for dress making. The dress forms used in this experiment were size 8 and six types: four from Korea and two from Japan. The instrument and tools for three-dimensional measurement was Whole Body 3D scanner (Exyma-WBS2H). The analysis program used in this experiment was Rapid Form 2004 PP1 (INUS technology, Inc, Korea). The measurement of dress forms was done three times with different sectional rotation-angles and its data were analyzed using SPSS WIN 10.0 Package. The following results were obtained: 1. With mean and standard deviation of each measured part, it was found out that the dress forms from two countries were different in size per each part. For example, the Japanese one was relatively large in middle hip and hip, compared to the Korean one. 2. The 3D analysis of the sectional rotation-angles revealed some differences between the two dress forms in sectional length per each part. 3. With cluster analysis results, it was found that there were definite differences among measurements per each part, especially in $30^{\circ}\;and\;45^{\circ}$ sections. 4. The proportion of the dress forms showed significant differences in the curvature between center and side section of the lower parts. In addition, the shapes on the horizontal section map of the four levels (waist, middle hip, hip, and bottom) were analyzed.

• Journal of the Korea Furniture Society
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• v.13 no.2
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• pp.75-84
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• 2002

The chairs are one of the most important furniture in this modern society, as we know that history of furniture is made of history of the chairs. Among the chairs, the stool, which made by only sit and legs, forms the basis of the chairs. The stool plays an important part in the human body to support and also help to make an agile movement In a short period of time. The stool is the minimum unit of chair, which made of least size and simple structure; therefore it fits to study basic knowledge of furniture making. For that reason, we can see occasionally the schools of furniture design departments have chosen the stool making course in their foundation students' studio classes. However, the professional study on the stool, such as the study on the posture for designing stool, has not been developed yet. This study presents basic Information of design for stool by analyzing various stools formatively.

• The Research Journal of the Costume Culture
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• v.29 no.6
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• pp.779-794
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• 2021

In this study, the sales status of female ball-jointed dolls and their parts were investi- gated and analyzed. Baseline data from 194 products and 54 brands on domestic and international Internet sites was gathered for the manufacture of ball-jointed dolls and the development of prototype costumes for them. The results are as follows. First, the sizes used for ball-jointed dolls are SD, USD, MSD, 13SD, and 70SD together with height. This study analyzed 39 sizes (15~70cm) by classifying them into numbered groups: 1 (15~22cm), 2 (23~33cm), 3 (35~51cm), 4 (53~62cm), and 5 (63~70cm). The price varied depending on the size; for example, 50cm dolls were approximately 45,000 won, while limited editions were sold at high prices, regardless of their size. They were classified into designs according to their body proportions and facial features as follows: 7- or 8-head-figure, 5-head figure, and 3-head figure, and were presented proportionally as images of women, adolescents, and infants. Second, the head was incised so that the top could be removed horizontally or the facial region vertically, allowing attachment of the eyeballs (which were either glass, resin, or acrylic) to the inside. More than 30 different colors were sold. Various wig styles were provided, including cut, short hair, and perm. These were made from human hair, heat-resistant fiber, and artificial hair. For the hands, there was a design expressing human hand gestures. For the feet, heels were in the form of wearing either high-heels or flat soles.

• Journal of Biomedical Engineering Research
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• v.16 no.4
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• pp.481-491
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• 1995

Endovaginal and endorectal receiver only surface coils were designed for MR imaging (MRI) and $^1H$ MR spectroscopy (MRS) for the uterine cervix and the prostate. The shape of endovaginal coil wire was rectangular with round corner. Size of the coil wire was empirically determined for 7cm and 4cm along the long and short axis, respectively. The coil wire loop was supported by acryl handle and bent about $150^{\circ}$ at one side of the loop considering the average angle of the cervix to the vagina. We called this as a "spoon-type endovaginal coil". The wire of the endorectal coil was made of the flexible materials so that the wire loop became long elliptic shape by pushing the acryl handle into the plastic tube for the comfort of patients when the coil was inserted into the cervix. Then, the shape was maintained to be circle by popping out handle. Conventional spin echo (SE) and fast spin echo (FSE) sequences were used as 71 and 72 weighted imaging sequences, respectively. Matrix size was 128~$256{\times}256$. FOVs for surface coil and body coil were 14cm and 24cm, respectively. 3D volume localized in vivo $^1H$ MR spectroscopy of the human cervix and prostate was performed using PRESS or STEAM localization method with the following parameters . TR=3 sec, TE=135 msec for PRESS or 30 msec for STEAM, NEX=2, NS=48, Sl=2048, and SW=2500 Hz. Using home-built endovaginal and endorectal coils, excellent T1- and T2-images were obtained to visualize early cervical and prostate tumors. 3D volume localized in vivo IH MRS was useful to differentiate the cancerous tissue from the normal tissue.