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Prognostic Significance of Pre-operative FDG-PET in Colorectal Cancer Patients with Hepatic Metastasis (대장직장암 간전이 환자에서 수술전 FDG PET의 예후인자로서의 중요성)

  • Lee, Hyo-Sang;Lee, Won-Woo;Kim, Duck-Woo;Kang, Sung-Bum;Lee, Kyoung-Ho;Lee, Keun-Wook;Kim, Jee-Hyun;Kim, Sang-Eun
    • Nuclear Medicine and Molecular Imaging
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    • v.43 no.5
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    • pp.429-435
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    • 2009
  • Purpose: The purpose of this study was to assess the prognostic value of preoperative FDG-PET in colorectal cancer (CRC) patients with hepatic metastasis (HM). Materials and Methods: 24 CRC patients (M:F=14:10; age, $63{\pm}10$ yrs) with HM who had undergone preoperative FDG PET were included. Cure-intent surgery was performed in all the patients and HMs were controlled using resection (n=13), radio-frequency ablation (RFA) (n=7), and resection plus RFA (n=4). Potential prognostic markers tested were maxSUV of primary tumor, maxSUV of HM, maxSUV ratio of HM over primary tumor (M/P ratio), histologic grade, CEA level, venous/lymphatic/nerve invasion, T stage, N stage, no. of HM, no. of lymph node metastasis, and treatment modality of HM. Results: 14 CRC patients developed a recurrence with a median follow-up duration of 244 days, whereas 10 patients did not develop recurrence with a median follow-up duration of 504 days. M/P ratios but other potential prognostic markers were significantly higher in the recurrent patients ($0.72{\pm}0.14$) than recurrence-free patients ($0.54{\pm}0.23$) (p=0.038). M/P ratio only was found to predict recurrence by Cox multivariate analysis (hazard ratio 37.7, 95% confidence interval 2.01-706.1, p=0.016). The 11 patients with lower M/P ratio of <0.61 had significantly better disease-free survival rate than the 13 patients with higher M/P ratio (${\geq}0.61$) (p=0.026). Conclusion: maxSUV ratio of HM over primary tumor (M/P ratio) may be useful for prognosis prediction of CRC patients with HM. Higher FDG uptake of HM than that of primary tumor may indicate a more advanced status in stage IV CRC.

A Study on Secondary School Girl Students' Life Style, Attitude toward Appearance and Clothing Attitude (중.고등학교 여학생의 라이프스타일, 외모에 대한 태도와 의복태도와의 관련 연구)

  • Lee, Eun-Hee
    • Journal of Korean Home Economics Education Association
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    • v.18 no.4 s.42
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    • pp.85-102
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    • 2006
  • The objectives of this study were to classify of life style of secondary school girl students, to investigate the relationships between life styles, attitude toward appearance and clothing attitude. The method of this study was survey research by using questionnaires. Subjects were 658(middle school students 327, high school students 331) girl students located in Jeollabukdo province. In this statistical analysis, SPSS 11.5 for Windows program was utilized to calculate frequency, mean, cronbach's ${\alpha}$, factor analysis, t-test, Pearson's correlation, multiple regression analysis. The results of this research were as follows: The results of analysing the factors to the response lifestyles, attitude toward appearance and clothing attitude emerged five dimensions(digital orientation, material orientation, positive activity, achievement orientation, frugality), three dimensions(needs conformity value toward appearance), five dimensions(fashion pursuit, gender attractiveness, self-expression, aesthetic, and modesty). High school girls' students showed higher digital orientation and positive activity life styles, attitude toward appearance, clothing attitude except of modesty. Clothing attitude variables except of modesty had positive correlations with lifestyles and attitude toward appearance. However, modesty of clothing had negative correlations with life styles and attitude toward appearance. As a conclusion, secondary school girl students' life styles and attitude toward appearance constituted important characteristics which could affect clothing attitude directly.

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Analysis of Influential Factors from Rainfall to Stream Water Quality in Small Forested Watershed - pH, dissolved oxygen, electrical conductivity - (산림유역내(山林流域內) 강수(降水)로부터 계류수질(溪流水質)에 미치는 영향인자(影響因子) 분석(分析) - pH, 용존산소(溶存酸素), 전기전도도(電氣傳導度) -)

  • Park, Jae-Hyeon;Woo, Bo-Myeong
    • Journal of Korean Society of Forest Science
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    • v.86 no.4
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    • pp.489-501
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    • 1997
  • This research was conducted to analyze the influence of the environmental factors on water quality such as pH, dissolved oxygen, and electrical conductivity of rainfall, throughfall, soil water(A and B layer), and stream water quality at a small forested watershed. Rainfall, throughfall, soil water(A and B layer), and stream water were sampled at the study sites in Kwanak Arboretum, Seoul National University in Mt. Kwanak for 14 months(Jul. 1, 1996~Aug. 31, 1997). Average rainfall pH value was 6.06(ranged from 5.02 to 6.60). Acid rain frequency(less than pH 5.6) was 16.7%. The lowest rainfall pH value was 5.02. Average of pH values in hydrological processes were decreasing in the following order, stream water>soil water [Prunus serrulata var, spontanea(B layer>A layer)]>throughfall(Prunus serrulata var. spontanea)>soil water [Carpinus laxiflora(B layer >A layer)]>throughfall(Carpinus laxiflora)>rainfall>soil water [Pinus rigida(B layer>A layer)]>throughfall(Pinus rigida). pH values of throughfall in Prunes serrulata var. spontanea and Carpinus laxiflora were higher in Pines rigida. Average of dissolved oxygen values in hydrological processes were decreasing in the order, stream water>throughfall(Carpinus laxiflora>Prunus serrulata var, spontanea>Pines rigida)>rainfall>soil water [Prunes serrulata var. spontanea(A layer)>Pines rigida(A layer)>Carpinus laxiflora(A layer)>Prunes serrulata var. spontanea(B layer)>Pines rigida(B layer)>Carpinus laxiflora(B layer)]. And average electrical conductivity values in hydrological processes were decreasing in the order, soil water (B layer>A layer)>throughfall(Pinus rigida>Prunes serrulata var, spontanea>Carpinus laxiflora)>stream water>rainfall. Multiple regression equations of electrical conductivity and $Mg^{2+}$, $Na^+$, total amount of cation, total amount of ion, and no. of before non-rain days in rainfall, throughfall, soil and stream water shows high significance(Multi R; 0.84).

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Study on Incidence and Improvement of Food Allergies for Prevention of Damage in Adolescents and Adults (청소년과 성인의 식품 알레르기 예방을 위한 식품 알레르기 발생 실태 및 개선안 연구)

  • Kim, Mi Jung;Sim, Ki Hyeon
    • Journal of the East Asian Society of Dietary Life
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    • v.24 no.4
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    • pp.514-528
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    • 2014
  • This study examined the actual state and future improvement of food allergies in adolescents and adults in order to prevent damage. In this survey, proportions of females, people in their 40s, college graduates, and office workers and housewives with allergies were higher than other groups. Exactly 41.1% of participants responded that they had experienced food allergies while 58.9% responded that they had not. According to their responses, the most common food allergy symptom involved the skin while whole-body allergic reactions were rare. Most respondents answered that frequency of their food allergies was two or three times. There was a variety of allergenic foods, including fast food, eggs, mackerel and milk, and instant food was ranked as the most allergenic food. Therefore, in order to protect consumers from damage caused by food allergens, the food allergen labeling system must be improved. A better food allergen labeling system should be implemented to avoid potential risks of allergic reactions and ensure national food safety.

Gastrointestinal Foreign Bodies: Review of 96 Cases (소아의 위장관 이물에 대한 고찰)

  • Lee, Min-Rye;Kang, Ki-Su;Jung, Hae-Sung;Seo, Ji-Hyoun;Lim, Jae-Young;Park, Chan-Hoo;Choi, Myoung-Bum;Woo, Hyang-Ok;Youn, Hee-Shang
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.5 no.2
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    • pp.136-142
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    • 2002
  • Purpose: Foreign body swallowing is common in children. Most of foreign bodies passed upper esophagus are removed spontaneously. But recently, therapeutic endoscopy in children is widely used. In this study, we reviewed gastric foreign bodies regarding types, location, interval from swallowing, complications, and treatment or method of removal. Methods: We reviewed medical records of 96 cases with foreign bodies in gastrointestinal tract at Department of Pediatrics in Gyeongsang National University Hospital (GNUH) from Feb 1987 to Feb 2002. Results: The peak age of patients (male=60, female=36) with foreign bodies in gastrointestinal tract was 2 to 5 years of age. Sixty two patients (64.5%) were asymptomatic. The location of foreign bodies in gastrointestinal tract were detected by simple X-ray in eighty one patients (86.0%), barium study (1 case), and gastroduodenoscopy in 37 cases. The most common location was stomach (63.5%). The most common foreign body was coin (41.7%). In thirty seven cases (38.5%), foreign bodies were removed with flexible gastroduodenoscopy. Fifty four patients (56.3%) visited GNUH in 24 hours after swallowing foreign bodies. The long interval (over 24 hours) of swallowing of foreign bodies is related with high frequency of endoscopic removal. Conclusion: The flexible gastroduodenoscopy was effective in diagnosis and removal of foreign bodies. Further studies for indication and validity of endoscopic removal of foreign bodies in upper gastrointestinal tract are needed.

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The effect of Lantus on glycemic control in children and adolescents with type 1 diabetes mellitus (1형 당뇨병을 가진 소아와 청소년에서 란투스 치료의 혈당 조절에 대한 효과)

  • Rhie, Young Jun;Chae, Hyun Wook;Kim, Ho Seong;Kim, Duk Hee
    • Clinical and Experimental Pediatrics
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    • v.50 no.6
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    • pp.565-569
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    • 2007
  • Purpose : With a duration of action of approximately 24 hours and peakless levels, Lantus is a more physiologic basal insulin analogue compared with NPH. The aim of this study was to compare the glycemic control of Lantus plus Humalog with that of premixed insulin in children and adolescents with type 1 diabetes mellitus. Methods : The subjects consisted of 25 patients with type 1 diabetes mellitus, aged 12-19 years, who changed their insulin regimen from premixed insulin to Lantus plus Humalog. Daily insulin doses, frequency of hypoglycemia, fasting blood glucose, C-peptide concentration and HbA1c before and 6 months after Lantus treatment were compared. 24 hour blood glucose of 11 patients among Lantus treatment group (n=25) and premixed insulin treatment group (n=10) were self-monitored and compared. Results : 6 months after Lantus treatment, the episodes of hypoglycemia were reduced by 50%(15.1 vs. 7.6 events/month), especially nocturnal hypoglycemia by 67%(6.7 vs. 2.5 events/month). HbA1c was reduced from 9.3% to 8.7% after Lantus treatment. Self-monitored blood glucose of Lantus treatment group at postbreakfast 30, 60, 90 and 120 minutes were 171.1, 169.5, 171.0 and 154.1 mg/dL respectively and lower than those of premixed insulin treatment group (259.7, 282.7, 280.0 and 250.9 mg/dL respectively). Conclusion : Compared with premixed insulin, Lantus plus Humalog is more effective in glycemic control and reduction in nocturnal hypoglycemia in children and adolescents with type 1 diabetes mellitus.

Effects of Palm Kernel Expellers on Productive Performance, Nutrient Digestibility, and White Blood Cells of Lactating Sows

  • Kim, J.;Seo, J.;Kim, W.;Yun, H.M.;Kim, S.C.;Jang, Y.;Jang, K.;Kim, K.;Kim, B.;Park, S.;Park, I.;Kim, M.K.;Seo, K.S.;Kim, H.B.;Kim, I.H.;Seo, S.;Song, M.
    • Asian-Australasian Journal of Animal Sciences
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    • v.28 no.8
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    • pp.1150-1154
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    • 2015
  • This experiment was conducted to investigate the effects of palm kernel expellers on productive performance, nutrient digestibility, and changes in white blood cells (WBC) of lactating sows. A total of 14 sows ($200{\pm}12kg$ of average body weight [BW]; 2.5 of average parity) were used and moved from gestation room to farrowing room on d 109 of gestation. Sows were randomly assigned to 2 dietary treatments in a completely randomized design. The treatments were a diet based on corn and soybean meal (CON) and CON added with 20% of palm kernel expellers (PKE). Sows were fed the treatments for 28 days (weaning) after farrowing. Blood was collected from each sow and 4 randomly selected piglets from each sow before farrowing or on d 3, 7, or 14 of lactation. Sows were fed respective treatments containing 0.2% chromic oxide from d 15 to 21 of lactation. Fecal samples were collected daily for the last 3 days after the 4-d adjustment period. Measurements were performances and WBC changes of sows and litter, nutrient digestibility of sows, and daily diarrhea of litter. Sows fed PKE had greater average daily feed intake (7.38 vs 7.10 kg/d; p<0.05) and lost less BW (-6.85 vs -8.54 kg; p<0.05) and backfat depth (-0.42 vs -0.71 mm; p<0.05) than those fed CON. However, there were no differences on digestibility of dry matter, nitrogen, and energy and weaning to estrus interval of sows fed either CON or PKE. Piglets from sows fed PKE gained more BW (203 vs 181 g/d; p = 0.08) and had less frequency of diarrhea (6.80 vs 8.56%; p = 0.07) than those from sows fed CON. On the other hand, no difference was found on preweaning mortality of piglets from sows fed either CON or PKE. Sows fed PKE had lower number of WBC (9.57 vs $11.82{\times}10^3/{\mu}L$; p = 0.09) before farrowing than those fed CON, but no difference on d 3 and 7. Similarly, piglets from sows fed PKE had also lower number of WBC (7.86 vs $9.80{\times}10^3/{\mu}L$; p<0.05) on d 14 of lactation than those from sows fed CON, but no difference on d 3 and 7. In conclusion, addition of 20% palm kernel expellers to lactation diet based on corn and soybean meal had no negative effects on productive performance, nutrient digestibility, and WBC changes of lactating sows.

Analysis on TV News Frame on Whistle-Blower: Focused on News Coverages on 'Kim Yong Chul' Claiming Samsung Group's Slush Fund (내부고발에 대한 텔레비전 뉴스 프레임: '김용철' 변호사의 삼성비리 고발사건을 중심으로)

  • Kim, Nam-Il
    • Korean journal of communication and information
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    • v.43
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    • pp.117-151
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    • 2008
  • This paper regards former Samsung lawyer Kim Yong-Chul's action of claiming Samsung Group's slush fund as typical Whistle-Blowing from inside. News frames in KBS, SBS TV were examined through comparative analysis. In formal feature, 'episodic news frame' hold an absolute majority in both stations. From news sources, the group of whistle-blower such as lawyer Kim Yong-Chul and civic groups was confronted with Samsung and state authorities including the Prosecutor, financial agencies. Analysis on the theme of news coverages demonstrated 5 frames: 'public announcing frame', 'news of conflict frame' 'demanding a close inquiry frame', 'declaration of conscience frame', 'causing social upheaval frame', Analysis result shows that 'public announcing frame' was most frequently used in reporting and there was distinction between KBS and SBS in 'declaration of conscience frame' and 'causing social upheaval frame'. Relatively KBS preferred 'declaration of conscience frame' and SBS would use 'causing social upheaval frame', from which reciprocal relation as media ownership could be analogized. Both media tend to make light of in-depth news coverages on structural issues or essential settlement and it is shown that both stations treated this situation with intriguing audiences as stressing sensitive parts in this event. Follow-up of changing process of 'declaration of conscience frame' through diachronic analysis on framing informs that additional exposure of 'Lee Yong Chul', former secretary in Nov 19, 2007 influenced increasing of frequency of using 'declaration of conscience frame'. However, news reporting on whistle-blower in KBS and SBS generally adheres to passive attitude of following changes in the surroundings rather than playing an active role in improving social recognition on whistle-blowing, which can induce to the spread of negative feature on it. Thus it is assumed that terrestial television broadcasting should regard whistle-blowing as contradiction in social structures and active depth reporting seems to be neded for improving social recognition on whistle-blowing.

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A Clinical Study of Acute Colonic Diverticulitis in Children (소아에서 발생한 급성 대장 게실염의 임상적 고찰)

  • Sim, Jae Hoon;Song, Keum Ho;Sim, Yun Jung;Cho, Do Jun;Kim, Dug Ha;Min, Ki Sik;Yoo, Ki Yang;Lee, Hae Ran;Lee, Kwan Seop
    • Clinical and Experimental Pediatrics
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    • v.46 no.11
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    • pp.1095-1100
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    • 2003
  • Purpose : Children with acute colonic diverticulitis(ACD), can be misdiagnosed with acute appendicitis. Methods : We reviewed 15 cases of ACD during five years, from January 1998 to June 2002 retrospectively. Results : Most patients(80%) with ACD in children presented with right lower quadrant pain. The primary diagnosis on admission was mostly acute appendicitis(87%), and all ACD in children occurred in the right colon. Fourteen patients were managed by conservative treatment including antibiotics. A follow-up study was performed in 15 patients. There were symptomatic recurrences in two patients, but no significant complication was noted. The frequency of ACD was 11.7 per 1000 acute appendicitis. Conclusion : ACD in children can mostly be cured by conservative treatment. It is prudent to choose the management through the diagnostic work up, including abdominal sonography and computed tomography, because there was no significant difference of clinical findings between ACD and acute appendicitis.

Urinary Calcium Excretion in Children with Primary Monosymptomatic Nocturnal Enuresis (일차성 단일증상성 야뇨증 환아에서 소변내로의 요칼슘배설에 대한 연구)

  • Chung, Woo-Yeong;Cho, Min-Hyun;Park, Yong-Hoon
    • Childhood Kidney Diseases
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    • v.15 no.2
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    • pp.146-153
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    • 2011
  • Purpose : Hypercalciuria has been suggested to be involved in the pathogenesis of nocturnal enuresis associated with polyuria. We have measured the amount of calcium excretion in the urine from children with monosymptomatic nocturnal enuresis and studied the association with enuresis. Methods : Thirty-six children (20 males and 16 females, age 5 to 15.6 years) presenting with monosymptomatic nocturnal enuresis were recruited for this study. Results : Among 36 patients, 6 patients had hypercalciuria, providing a 16.7% frequency. The mean Ca/Cr ratio of hypercalciuria group showed $0.23{\pm}0.10$ on daytime, and $0.33{\pm}0.10$ on nighttime showing higher values in nighttime, but it was not statistically significant. Average 24 hour calcium excretion was 8.95 mg/kg. Night/day time urine volume ratio in hypercalciuria group was $0.87{\pm}0.20$, and that in normocalciuria group was $0.81{\pm}0.33$, also showing no difference. Daytime Ca/Cr ratio and nighttime Ca/Cr ratio from all enuresis patients showed a significant correlation (P=0.0001). However, Ca/Cr ratio between daytime and nighttime urine volume had no significant correlation, respectively (daytime P=0.08; nighttime P=0.07). Also, daytime and nighttime Na concentration, urea concentration, and osmolality also had no significant correlation with urine Ca/Cr ratio, respectively. Conclusion: Hypercalciuria shown in some of enuresis patients is not directly caused by primary monosymptomatic nocturnal enuresis.