• KOREAN JOURNAL OF CROP SCIENCE
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• v.49 no.5
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• pp.423-428
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• 2004

Soybean seeds contain high amounts of isoflavones that display biological effects and isoflavone content of soybean seed can vary by year, environment, and genotype. Objective of this study was to identify quantitative trait loci that underlie isoflavone content in soybean seeds. The study involved 85 $F_2$ populations derived from Korean soybean cultivar 'Kwangkyo' and wild type soybean 'IT182305' for QTL analysis associated with isoflavone content. Isoflavone content of seeds was determined by HPLC. The genetic map of 33 linkage groups with 207 markers was constructed. The linkage map spanned 2,607.5 cM across all 33 linkage groups. The average linkage distance between pair of markers among all linkage groups was 12.6 cM in Kosambi map units. Isoflavone content in $F_2$ generations varied in a fashion that suggested a continuous, polygenic inheritance. Eleven markers (4 RAPD, 3 SSR, 4 AFLP) were significantly associated with isoflavone content. Only two markers, Satt419 and CTCGAG3 had F-tests that were significant at P<0.01 in $F_2$ generation for isoflavone content. Interval mapping using the $F_2$ data revealed only two putative QTLs for isoflavone content. The peak QTL region on linkage group 3, which was near OPAG03c, explained $14\%$ variation for isoflavone content. The peak QTL region on linkage group 5, which was located near OPN14 accounted for $35.3\%$ variation for isoflavone content. Using both Map-Maker-QTL $(LOD{\geq}2.0)$ and single-factor analysis $(P{\leq}0.05)$, one marker, CTCGAG3 in linkage group 3 was associated with QTLs for isoflavone content. This information would then be used in identification of QTLs for isoflavone content with precision

• Journal of the Korea Academia-Industrial cooperation Society
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• v.8 no.6
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• pp.1566-1571
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• 2007

Oligodeoxyribonucleotide bearing the di-acetylenic linkage has been prepared. Staring from 5-Iodo-2'-deoxyuridine(1), a four-step sequence, consisting of the Pd(0)-catalyzed Heck-type C-C coupling with acetylenic group, protection of 5'-hydroxy group, generation of acetylenic hydrogen, and Glaser oxidative coupling reaction leads to the dimeric oligodeoxyribonucleotide(5).

• Health Policy and Management
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• v.4 no.2
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• pp.27-57
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• 1994

The objective of running a long-term care institution is to provide services helpful for maintaining, supporting, and improving elderlies' optimum level of physical, mental, and psychosocial functioning. For the purpose of analyzing the current situations of institutional long term care facilities in Korea, 27 facilities were selected proportionately from each of the cities and provinces, out of the total 152 facilities. About 20% of those who were institutionalized during 25 August through 2 Qctober 1993, the 391 elderlies were chosen on a systematic random basis. The instrument of this study was developed by modifying the tools of CARE, MAI and PCTC. A multivariate approach of discriminant analysis and clustering technique were employed for this study. The Stiudy reveals that there is no clear differentiation of goals and functions among the longterm care institutions in Korea. Staffing patte군 of long-term care facilities shows a shortage of nurses, physical therapists, and dieticians. The linkage between acute care facilities and long-term care is weak, and administration of long-term care faciltiy is carried out by non-professionals. They are responsible for assessing health status before entering the facility, and evaluating elderlies' care. Therefore, it is not surprising to find that most of the facilities have accommodated agede regardless of their real needs and health status. Based upon findings of the analysis, this study has classified long-term care facilities into four types : Type I is to help elderlies maintain independence in daily living activities. Type II facilities have the objective of maintaining and improving the current level of elderlies' function. Type III is to maintain maximum independence of elderlies in activities of daily living. And Type IV is identified for the group of facilities designed to restore or improve functional abilities of elderlies. In conclusion, the following suggestions are made : the need for long-term care should be assessed by multidimensional measurement. Institutional long-term care facilities should be classified and developed in response to type of type of care and service need. Both acute and long-term care facilities should be linked together in order to support the evaluation of service operation and program development.

• Mycobiology
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• v.49 no.4
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• pp.406-420
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• 2021

Gloeostereum incarnatum has edible and medicinal value and was first cultivated and domesticated in China. We sequenced the G. incarnatum monokaryotic strain GiC-126 on an Illumina HiSeq X Ten system and obtained a 34.52-Mb genome assembly sequence that encoded 16,895 predicted genes. We combined the GiC-126 genome with the published genome of G. incarnatum strain CCMJ2665 to construct a genetic linkage map (GiC-126 genome) that had 10 linkage groups (LGs), and the 15 assembly sequences of CCMJ2665 were integrated into 8 LGs. We identified 1912 simple sequence repeat (SSR) loci and detected 700 genes containing 768 SSRs in the genome; 65 and 100 of them were annotated with gene ontology (GO) terms and KEGG pathways, respectively. Carbohydrate-active enzymes (CAZymes) were identified in 20 fungal genomes and annotated; among them, 144 CAZymes were annotated in the GiC-126 genome. The A mating-type locus (MAT-A) of G. incarnatum was located on scaffold885 at 38.9 cM of LG1 and was flanked by two homeodomain (HD1) genes, mip and beta-fg. Fourteen segregation distortion markers were detected in the genetic linkage map, all of which were skewed toward the parent GiC-126. They formed three segregation distortion regions (SDR1-SDR3), and 22 predictive genes were found in scaffold1920 where three segregation distortion markers were located in SDR1. In this study, we corrected and updated the genomic information of G. incarnatum. Our results will provide a theoretical basis for fine gene mapping, functional gene cloning, and genetic breeding the follow-up of G. incarnatum.

• Journal of the Korean Society of Manufacturing Process Engineers
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• v.20 no.9
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• pp.42-47
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• 2021

A one-touch descending lifeline that can easily be installed and rapidly evacuated in the event of a fire accident in high-rise buildings was proposed to overcome difficulties of conventional descending lifeline such as complex installation methods and procedures. However, this lifeline exhibits limitations such as restrictions in installation location and large apparatus size. Therefore, this paper proposes a sliding-type descending lifeline, which has a similar operation to that of current one-touch descending lifeline and solves the aforementioned limitations. A double square link mechanism including a sliding four-bar linkage is proposed and the descending lifeline support is redesigned to unfold in two different planes, allowing 3D movement. Additionally, the shape of the support frame is designed to obtain two attachment surfaces that can be attached to a wall, irrespective of the angle between the window and the inner wall. FEA analysis using ABAQUS is performed to ensure that the robustness of the presented support complies with the Fire Control Act Enforcement Decree. Finally, the feasibility of the proposed sliding one-touch descending lifeline is verified through fabrication.

• Journal of Korea Technology Innovation Society
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• v.15 no.1
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• pp.47-75
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• 2012

Basic research have contributed to technological growth or economic growth in U.S. Specially recent studies say that universities also contribute to economic development through scientific activities like science research, education, technology transfers. But we can not assure whether scientific knowledge was connected to real technology or economic performance, and it is difficult to figure out the effect of scientific output. "What is the exact performance of scientific knowledge?" It is still obscure. In this context, this paper analyzes characteristics of the linkage of science and technology. Data are U.S. R&D expenditure, scientific articles, citation of articles in U.S. patents by fields and sectors. As a result, university sector has the most weight of the linkage of science and technology. But, in relative connection rate analysis, industrial sector's is stronger than any other sectors. In the field analysis, linkage of science and technology is very strong in Chemistry, Physics, Biological sciences fields. And recently the linkage was increased in the fields of Computer science, Agricultural science, Engineering. Finally, this paper supports funding policy or estimation policy of government to product of scientific knowledge. University sector is still important because it has the most weight of the linkage. Scientific knowledge of industrial sector is also important. The connection rate of industrial science is the strongest in all sectors. And this research classify the R&D type by science fields. Considering the differences of science fields is needed to product science knowledge effectively.

• Journal of Preventive Medicine and Public Health
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• v.37 no.4
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• pp.366-372
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• 2004

Objectives : This study was conducted to propose a new transmission/disequilibrium test(TDT) to test the linkage between genetic markers and disease-susceptibility genes based on haplotypes. Simulation studies were performed to compare the proposed method with that of Zhao et al. in terms of type I error probability and powers. Methods : We estimated the haplotype frequencies using the expectation-maximization(EM) algorithm with parents genotypes taken from a trio dataset, and then constructed a two-way contingency table containing estimated frequencies to all possible pairs of parents haplotypes. We proposed a score test based on differences between column marginals and their corresponding row marginals. The test also involved a covariance structure of marginal differences and their variances. In simulation, we considered a coalescent model with three genetic markers of biallele to investigate the performance of the proposed test under six different configurations. Results : The haplotype-based TDT statistics, our test and Zhao et al.'s test satisfied a type I error probability, but the TDT test based on single locus showed a conservative trend. As expected, the tests based on haplotypes also had better powers than those based on single locus. Our test and that of Zhao et al. were comparable in powers. Conclusion : We proposed a TDT statistic based on haplotypes and showed through simulations that our test was more powerful than the single locus-based test. We will extend our method to multiplex data with affected and/or unaffected sibling(s) or simplex data having only one parent s genotype.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.25 no.12
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• pp.1723-1728
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• 2021

C-ITS is an intelligent transportation system that can improve transportation convenience and traffic safety by collecting, managing, and providing traffic information between components such as vehicles, road infrastructure, drivers, and pedestrians. In Korea, road infrastructure is being built across the country through the C-ITS project, and various services such as real-time traffic information provision and bus operation management are provided. However, the current state-of-the-art road infrastructure and information linkage system are insufficient to build C-ITS. In this paper, considering the continuity of time in various spatial aspects, we proposed a group-type network-based traffic situation recognition system that can recognize traffic flows and unexpected accidents through information linkage between traffic infrastructures. It is expected that the proposed system can primarily respond to accident detection and warning in the field, and can be utilized as more diverse traffic information services through information linkage with other systems.

• KIEE International Transaction on Electrical Machinery and Energy Conversion Systems
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• v.4B no.2
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• pp.47-53
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• 2004

The salient pole rotor type single phase SRM (switched reluctance motor) uses radial and axial direction magnetic flux simultaneously. Therefore, the output power per unit volume is very high and the shaft length is shorter than other types of SRMs with the same output. Furthermore, it can be manufactured with low cost owing to its simple structure and driving circuit. The prototype was designed using the theory of the traditional rotating machine and 3D FEM analysis. On this paper, the experiment apparatus, which includes the fabricated prototype in previous researches, was fabricated to measure the current and voltage of the prototype. Then the flux linkage, inductance and magnetic co-energy were calculated using the experimental results. Finally, the measured magnetic co-energy was compared with the simulated magnetic co-energy.

• 한국정보디스플레이학회:학술대회논문집
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• 2008.10a
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• pp.816-819
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• 2008

A negative photoresist formulation was developed utilizing synthesized UV monomers containing imide linkage, photoinitiator, UV oligomer, and alkali developable polymer matrix. It was found that via-holes with good resolution, high transmittance and thermal resistance could be obtained by photolithographic process utilizing the negative-type photoresist formulations.