• Korean Journal of Radiology
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• v.22 no.12
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• pp.1985-1995
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• 2021

Objective: Although the liver-to-spleen volume ratio (LSVR) based on CT reflects portal hypertension, its prognostic role in cirrhotic patients has not been proven. We evaluated the utility of LSVR, automatically measured from CT images using a deep learning algorithm, as a predictor of hepatic decompensation and transplantation-free survival in patients with hepatitis B viral (HBV)-compensated cirrhosis. Materials and Methods: A deep learning algorithm was used to measure the LSVR in a cohort of 1027 consecutive patients (mean age, 50.5 years; 675 male and 352 female) with HBV-compensated cirrhosis who underwent liver CT (2007-2010). Associations of LSVR with hepatic decompensation and transplantation-free survival were evaluated using multivariable Cox proportional hazards and competing risk analyses, accounting for either the Child-Pugh score (CPS) or Model for End Stage Liver Disease (MELD) score and other variables. The risk of the liver-related events was estimated using Kaplan-Meier analysis and the Aalen-Johansen estimator. Results: After adjustment for either CPS or MELD and other variables, LSVR was identified as a significant independent predictor of hepatic decompensation (hazard ratio for LSVR increase by 1, 0.71 and 0.68 for CPS and MELD models, respectively; p < 0.001) and transplantation-free survival (hazard ratio for LSVR increase by 1, 0.8 and 0.77, respectively; p < 0.001). Patients with an LSVR of < 2.9 (n = 381) had significantly higher 3-year risks of hepatic decompensation (16.7% vs. 2.5%, p < 0.001) and liver-related death or transplantation (10.0% vs. 1.1%, p < 0.001) than those with an LSVR ≥ 2.9 (n = 646). When patients were stratified according to CPS (Child-Pugh A vs. B-C) and MELD (< 10 vs. ≥ 10), an LSVR of < 2.9 was still associated with a higher risk of liver-related events than an LSVR of ≥ 2.9 for all Child-Pugh (p ≤ 0.045) and MELD (p ≤ 0.009) stratifications. Conclusion: The LSVR measured on CT can predict hepatic decompensation and transplantation-free survival in patients with HBV-compensated cirrhosis.

• The Journal of the Korea Contents Association
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• v.14 no.7
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• pp.395-406
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• 2014

This research observes how an adolescent's usage of social network services is related with media use time, and also tries to verify how a parent's participation in acting to limit usage time serves as a mediating effect. For this analysis, data from The Korean Information Society Development Institute [Korea Media Panel Research] was used, being a survey conducted on 1,572 students from primary to secondary and high schools nationwide. The subjects' gender in the final analysis was 818 male students and 754 female students. In addition, primary school students consisted of 672 individuals, 416 were from secondary and 484 from high schools. To verify the appropriateness of the model proposed in this research, analyzed through the structural equation, using social network services(SNS) was not shown to have an effect on media usage time. However, there was an indirect effect from the use of alternative activities. In addition, the parent's limitation of usage showed no effect on media use time. This research attempts to identify the reasons why parents' limiting the usage time, along with alternative activities, do not have any significant effect in reducing media usage time in this era of smart media evolution. Further, this research hopes to suggest meaningful and political implications for the nation and society to understand and resolve media addiction.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.9
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• pp.57-67
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• 2016

This study is designed to investigate the differences of ferritin and hemoglobin levels according to the vitamin D state in 23577 Korean adult subjects by using data from the Korea National Health and Nutrition Examination Survey IV, V. Ferritin and hemoglobin levels are analyzed based on the quintile of vitamin D levels by a generalized linear model. The results of analysis showed that there was a relationship between vitamin D state and hemoglobin levels in females in the reproductive status group (p<0.001). In case of ferritin, there was a relationship with vitamin D state in females in reproductive status group (p<0.001) and males under 65 years old group (p<0.05). Within the male group, high ferritin correlated with low vitamin D state; but in the female group, high ferritin correlated with high vitamin D state. Therefore, it is possible for the ferritin level to be affected by vitamin D state in females in reproductive status group and males under 65 years old group.

• Toxicological Research
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• v.22 no.3
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• pp.221-228
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• 2006

Bonogen shampoo is composed of several plant extracts which are known to be used in oriental medicine. This study was carried out to investigate the effects of Bonogen shampoo on hair growth in an alopecia model of C57BL/6 mice. There were eight male and female experimental groups including distilled water(DW: negative control), a commercial shampoo[M], 3% minoxidil (MXD) and Bonogen shampoo(BNG). Dorsal skin hair of six-week-old mice was trimmed with an electric clipper carefully not to damage the skin. The next day, mice without skin scratch were selected, randomized and separated in 10 mice per group. The test compounds were topically treated with 0.15 ml per mouse or dorsal skin for 21 days daily and then washed thoroughly with DW. The hair regrowth was determined photographically at 0, 4, 7, 10, 15, 18, and 21 days and histologically at day 21. No clinical signs were observed in all mice. Although body weight was slightly increased in 3% MXD group than other groups, it was not significant. Hair regrowth began to be promoted after 14 days and appeared a distinct regrowth pattern in all animals by topical treatment of test compounds at 18 days. In particular, the topical treatment of bonogen shampoo or 3% MXD for 21 days to dorsal skin accelerated hair regrowth faster than DW or M shampoo. At 21 days, the hair regrowth promotion speed was in order of 3% MXD>BNG>M>DW. The bonogen shampoo or 3% MXD also promoted hair follicle elongation compared to the negative control. These results suggest that bonogen shampoo has hair growth promoting activities and may be useful for treatment of bald or alopecia.

• Korean Educational Research Journal
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• v.43 no.1
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• pp.125-152
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• 2022

The purpose of this study is to examine the differences of perceptions of teachers and students regarding teaching skills. For the analysis, data was collected by ICALT(International Comparative Analysis of Learning and Teaching) class observation tool and students survey called My Teacher Questionnaire. a student survey. The data of teachers and students can be compared because as the two tools have seven common domains(Safe and stimulating learning climate, Efficient organization, Clear and structured instructions, Intensive and activating teaching, Adjusting instructions and learner processing to inter-learner differences, Teaching learning strategies, Learner engagement). In 2016, in Daejeon, Chungbuk and Chungnam. trained teachers collected data from 106 classes, and 2,866 students responded the survey. The reliability and validity of the two tools, class observation and MTQ(My Teacher Questionnaire) are proven to be satisfactory for use in Korean schools. Students perception on teaching was high, particularly when students are in lower grades and learning major subjects like English, Korean, and math. The domain of higher teaching skills, male students show higher perceptions while female students reported higher perceptions on lower-level teaching skill domains. To compare the perceptions of teachers and students, the predictive reliability of students engagement against teaching skill domains was used. Teachers showed higher predictive reliability on lower teaching skill domains while students showed higher predictive reliability on higher teaching skill domains. It is recommended for further study to develop a professional development model using a teacher class observation tool and the My Teacher Questionnaire for pre-service teachers and school teachers.

• Journal of the Korean Society of Clothing and Textiles
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• v.32 no.12
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• pp.1825-1836
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• 2008

Many applications in computer graphics require complex and highly detailed models. However it is often desirable to use approximations in place of excessively detailed models in order to control the processing time. Thus, we aim to develop a notion of optimal matrix to simplify surface which can rapidly obtain the high quality 2D patterns flattening 3D surface as follows. Firstly, two 3D bodies are modeled based on existing Size Korea data. Secondly, each model is divided by shell and block for its pattern draft. Thirdly, each block is flattened by grid and bridge method. Finally, we selected the optimal matrix and demonstrated the efficiency and quality of the proposed method. This proposed approach accommodates surfaces with darts, which are commonly used in the clothing industry to reduce the deformation of surface forming and flattening. The resulting optimal matrix could be an initiation of standardization for pattern flattening. It is expected that this method could facilitate much better approximation in both efficiency and precision.

• Journal of Food Hygiene and Safety
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• v.25 no.2
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• pp.143-147
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• 2010

Chronic exposure to Arsenic (As) causes significant human health effects including various cancers. Total As concentrations from 300 polished rice samples cultivated near the mining areas in Korea were analyzed to estimate a probabilistic assessment of human health risk from As-contaminated rice. The mean of total As concentrations in rice was 0.09 mg/kg and lognormal distribution model was set for total As concentrations. Human health risk for As in rice was estimated using gender-specific rice consumption data and average daily dose (ADD). While cancer risk (CR) and hazard quotient (HQ) were calculated using oral cancer slope factor (OCSF) and Reference dose (RfD) suggested by the U.S. EPA. Mean of CR posed by total As was 2.16 (for male) and 1.83 (for female) per 10,000. The HQ for general population from rice cultivated near the mining areas in Korea was below 1 as the $50^{th}$ percentile of general population. However, less than 10% of general population consuming rice cultivated near the mining areas would exceed 1.0. This result is similar with those from each gender-specific group.

• Korean Journal of Ecology and Environment
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• v.33 no.3 s.91
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• pp.267-273
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• 2000

Temperature-associated emergence patterns for a hydropsychid caddisfly, Hydropsyche kozhantschikovi, were studied from the Wangsuk creek in Kyonggi-do from April to June in 1999. Emerging adults were quantitatively collected by pyramidshaped emergence traps. Water temperature was hourly monitored in 1999. The emergence began at April 15 when the daily mean water temperature rose to ca. $10^{\circ}C$: it rapidly increased and peaked in ca. 10 days, and continued to May 25, lasting 40 days since the starting date. The average number of emerged adults was $35.8\;inds./m^2$ and their sex ratio was male (M) : female (F) = 1 : 2.04. The emergence of males was ca. 2 days earlier than that of females. Daily, the emergence was a bigeminans pattern representing the major peak (66.7%) just after dark ($19:00{\sim}21:00$) and theminor peak (11.1%) just before dawn ($05:00{\sim}07:00$). According to our degree dayaccumulation (DD) model, it respectively required 453.89DD (M: 440.48DD and F: 473.97 DD), 615.71DD (M: 610.18DD and F: 622.09DD), and 820.24DD (M: 828.25DD and F: 804.71DD) to begin, to reach the peak, and to finish the emergence.

• Journal of Digital Convergence
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• v.19 no.1
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• pp.443-451
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• 2021

The purpose of this study is to investigate the mediating effects of depression, academic helplessness, and smartphone addiction tendency in the relationship between self-esteem and grit of adolescents. Data from the 2018 (first-year) Korean Children and Youth Panel Survey were used in this study. The subjects of this study were 1,375 male and 1,166 female students in seventh grade school. The multiple mediation model analysis was conducted using the SPSS and PROCESS macro program. The results of this study are as follows. First, there was a positive correlation between self-esteem and grit, while self-esteem and grit had negative correlations with depression, academic helplessness, smartphone addiction. Second, it was found that the relationship between self-esteem and grit was mediated by depression, academic helplessness, and smartphone addiction tendency, respectively, and furthermore, it was found that all pathways mediated sequentially were also significant. These results suggest that education and intervention considering self-esteem, depression, academic helplessness, and smartphone addiction to be useful as a way to help adolescents develop interest in specific goals and continue their efforts in these days when smartphone use is common.

• The Korean Journal of Applied Statistics
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• v.33 no.6
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• pp.777-789
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• 2020

COVID-19 has been rapidly spread world wide since late December 2019. In this paper, our interest is to estimate distribution of incubation time defined as period between infection of virus and the onset. Due to the limit of accessibility and asymptomatic feature of COVID-19 virus, the exact infection and onset time are not always observable. For estimation of incubation time, interval censoring technique is implemented. Furthermore, a competing risk model is applied to estimate the case fatality and cure fraction. Based on the result, the mean incubation time is about 5.4 days and the fatality rate is higher for older and male patient and the cure rate is higher at younger,female and asymptomatic patient.