• Title/Summary/Keyword: Th2 cell

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Immunoregulatory Action of Comus officinalis Sieb.et Zucc (산수유의 면역조절작용)

  • Lee Won Bum;Jung Han Sol;Kwon Jin;Oh Chan Ho;Lee Kwang Gyu
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.16 no.2
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    • pp.267-271
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    • 2002
  • The purpose of this research was to investigate the immunoregulatory effect, apoptosis of L 1210 leukemia cells of Comus officinalis Sieb.et Zucc. The proliferation of cultured splenocytes and thymocytes were enhanced by the addition of SSY. Splenic, thymic and mesenteric lymph node-T lymphocytes, especially TH cells was significantly increased in SSY-administered (p.o. for 7 days) mice. SSY treatment induced the apoptosis of L1210 mouse leukemia cells. In addition, SSY accelerated the phagocytic activity and nitric oxide production in peritoneal macrophages. These results suggest that SSY have an immuno-regulatory property and anti-cancer effect.

Low degree of homogeneity issue on the effective moduli of plain weave textile composites (기하학적 매개변수에 의한 평직복합재료의 저 균일도 문제)

  • 우경식;서영욱
    • Composites Research
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    • v.13 no.2
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    • pp.8-21
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    • 2000
  • In th is paper. the low degree of homogeneity issue in the effective modulus was studied for plain weave textile composites. Unit cell analyses were performed using multi-field macroelements. The effective moduli were calculated for finite and infinite configurations and the statistics assessment of the results was presented. Results indicated that the effective modulus of plain weave textile composites depended strongly on the fiber tow phase shift angles and the number of layers. As the number of layers increased, however, the distribution of the modulus showed concentration and higher degrees of homogeneity was attained.

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Effect of Insamyangyoung-tang on the Specific Immune Response in BALB/c Mice (인삼양영탕이 생쥐의 특이적 면역반응에 미치는 영향)

  • Eun Jae Soon;Kim Dae Keun;Choi Hoon;Oh Chan Ho
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.16 no.4
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    • pp.729-733
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    • 2002
  • The purpose of this research was to investigate the effects of Insamyangyoung-tang water extract (IYT) on the specific immune response in BALB/c mice. When IYT (500mg/kg) was administerd p.o. once a day for 7 days to BALB/c mice, the cell viability of thymocytes and splenocytes was increased. Also, IYT increased the population of CD4/sup +/ cells in thymocytes and the population of Thy1/sup +/ cells and CD4/sup +/ cells in splenocytes. In addition, IYT increased the production of γ -interferon and interleukin-2 from thymocytes and the production of γ -interferon from splenocytes. These results suggest that IYT enhances the specific immune response via activation of Th1 cells in thymocytes and splenocytes.

Effects of Silicon on Stomatal Size and Frequency in Rice Plants (규소가 벼의 엽신 기공 크기와 밀도에 미치는 영향)

  • 강양순
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.36 no.1
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    • pp.70-73
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    • 1991
  • Stomatal frequency and size of rice plant grown in the different silicon levels of the culture solution in phytotron were observed on both side of the 7th leaf blade. By the application of silicate, stomatal frequency and rates of stoma cell area to the leaf area were remarkably reduced in Milyang 23. It could be considered as favorable characteristics which might be reduced the transpira-tion rate from leaf surface of rice plant besides presence of cuticle-silica double layer in leaf surface.

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Agricultural Fertilizers as Economical Alternative for Cultivation of Haematococcus pluvialis

  • Dalay Meltem Conk;Imamoglu Esra;Demirel Zeliha
    • Journal of Microbiology and Biotechnology
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    • v.17 no.3
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    • pp.393-397
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    • 2007
  • A Haematococcus pluvialis strain isolated from the ruins of Ephesus in Turkey was investigated as regards its adaptation to laboratory conditions and maximum growth rate. In the first stage of the experiment, the growth of H. pluvialis was compared in common culture media. Furthermore, in an effort to minimize the culture costs, the second stage of the experiment compared the growth rate in the culture medium selected in the first stage with that in commercial plant fertilizers. The results demonstrated that the maximum cell concentration of 0.90 g/l, corresponding to a growth rate of $0.150d^{-1}$, was found with an N-P-K 20:20:20 fertilizer under a light intensity of $75{\mu}mol$ photons $m^{-2}s{-1}$ on the $12^{th}$ day of cultivation.

A Theoretical Study of Ultrasound Scattering by Blood (혈액에 의한 초음파 산란의 이론적 고찰)

  • 최재준;홍승홍
    • Journal of Biomedical Engineering Research
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    • v.2 no.1
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    • pp.15-20
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    • 1981
  • In this study, the scattering of ultrasound by blood is theoretically studied. At first, the Chernow equation which represents acoustic propagation inside the region of inhomogenieties is modified to be fitted for blood. Then, scattering amplitude and scattering Cross-section at the far-field region are obtained from this equation. In this case, hemotocrit is assumed to be less than 26 per cent, and the red blood cell is modeled as independent scatterer. This study also develops a practical approximation for the backscattering of periodic sinewave bursts by a volume of randomly distributed scatterers, i.e., whole red blood cells. This expression for the received backscattering ultrasound pressure after the n-th burst of narrowband transducer is obtained from an ideal continuous wave transducer's response.

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The Role of Probiotics in Infants and Children with Food Allergy (Probiotics와 영아와 소아의 식품 알레르기)

  • Park, Kie Young
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.11 no.sup1
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    • pp.127-135
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    • 2008
  • According to the hygiene hypothesis, westernized and urbanized life style leads to the increase of allergic disease. This hypothesis supports the use of probiotic therapy for the prevention or treatment of food allergy. The probiotics which contains potentially beneficial microorganism have been used for the treatment of some gastrointestinal disorders and atopic disease as dietary supplements. Many results of studies support the immunologic bases of probiotics therapy. The most important mechanism is that probiotics suppress Th2-skewed immunity as the stimulation of regulatory T cell. The difficulties of diagnosis of food allergy, variable symptoms, many kinds of microorganism, diet style and non-standardized study designs are attributed to the variety and controversy of the effectiveness of probiotics in food allergy with infant and children. More studies is needed to confirm the efficacy of probiotics in infant and children with food allergy.

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The effect of regular exercise on immune response and hormone (규칙적인 운동이 면역반응 및 호르몬에 미치는 영향)

  • Park, Sang Kyu
    • The Korean Journal of Emergency Medical Services
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    • v.5 no.1
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    • pp.15-22
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    • 2001
  • This study has measured the pulmonary function by treadmill test for 6 young women who were in twenties, and analyzed the respiratory-circulatory function and the change of hormone and immune response after performing the exercise program (60% severity) for 10 weeks. The results are as follows; 1. 10 weeks regular exercise made a decrease in weight and body fat proportion, and improved the respiratory-circular function by increasing the maximum oxygen absorption and ventilation. 2. 10 weeks regular exercise made a significant increase in count of WBC, lymphocyte, and T lymphocyte, but a significant decrease in B lymphocyte. NK cell also showed an increase in counts, but insignificant. 3. 10 weeks regular exercise made a significant increase in blood norepinephrine level. Epinephrine and cortisol also showed an increase in count, but insignificant. In summary, it suggested that 10 weeks regular exercise improves the immune function by decrease in body fat, increase in respiratory-circular function and metabolic efficiency, and also by raising Th/Ts ratio (an increase in count of WBC, lymphocyte, and T lymphocyte, but a decrease in suppressor T lymphocyte).

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pH Sensing Properties of ISFETs with LPCVD Silicon Nitride Sensitive-Gate

  • Shin, Paik-Kyun;Thomas Mikolajick;Heiner Ryssel
    • Journal of Electrical Engineering and information Science
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    • v.2 no.3
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    • pp.82-87
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    • 1997
  • Ion-Sensitive Field-Effect Transistors(ISFETs) with LPCVD silicon nitride as a sensitive gate were fabricated on the basis of a CMOS process. The silicon nitride was deposited directly on a poly silicon gate-electrode. Using a specially designed measuring cell, the hydrogen ions sensing properties of the ISFET in liquid could be investigated without any bonding or encapsulation. At first, th sensitivity was estimated by simualtions according to the site-binding theory and the experimental results were analysed and compared with simulated results. The measured dta were in good agreement with the simulated results. The silicon nitride based ISFET has good linearity evaluated from correlation factor ($\geq$0.9998) and a mean pH-sensitivity of 56.8mV/pH. The maximum hysteresis width between forward(pH=3\longrightarrowpH=11)- and backward(pH=11\longrightarrowpH=3) titration was 16.7mV at pH=6.54.

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Effects of Pinelliae Rizoma (PR) on asthma induced intra-nasal instillation of ovalbumin in mice (반하가 난황으로유발된 생쥐의 알레르기성 천식에 미치는 영향)

  • Jeong, Dong-Hwan;Kim, Jong-Han;Park, Su-Yeon;Choi, Jeong-Hwa
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.21 no.1
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    • pp.38-54
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    • 2008
  • Objective : This study was designed to investigated effects of Pinelliae Rizoma (PR) on asthma Methods : Detecting antigen specific antibody isotypes, cytokines in serum and bronchoalveolar lavage fluid (BALF). In addition, the present author also investigated changes in weight of spleen and proliferation rates of splenocytes. Finally, histopathological observation of the lung tissue was also investigated. Results : Oral administration of PR lowered OVA specific IgE levels in serum, IgG1 levels in serum and BALF. PR also decreased production levels of IL-4 in BALF. In addition, total cells in BALF were decreased by oral administration of PR effectively. In histapathological observation, PR group showed downward tendency of inflammatory cell infiltration around small vessels. Conclusion : PR is useful to treat patients with asthma and the mechanisms are related in suppression of Th2 skewing reactions.

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