• 대한수의학회지
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• 제33권2호
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• pp.263-268
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• 1993

This study was conducted to detect the serum antibody of toxoplasma in swine from breeding-pig, rearing-pig farm and slaughtered pig in abattior by latex agglutination(LA) test. The perfomance of LA test was carried out with commercial Toxo-MT kit(Eiken Chemical Co.)by Tsubota and Ozawa's method. The cut-off titer of positive and negative reactions by Toxo-MT antigen used in this experiment was determined as the serum titer of 1 : 32. Positive rate of toxoplasma antibody from the total of 823 serum samples by LA test was 17.0%(140 cases). And positive rates of toxoplasma antibody against serum samples of 194 from breeding-pig farm, 273 from rearing-pig farm and 356 from abattior were 91 cases(46. 9%), 23 cases(8.4%) and 26 cases(7.3%), respectively. The distributions of serum antibody titers in 823 test sera by LA test were shown 51 cases(36.3%) in 1:32, 40(28.6%) in 1:64, 17(12.1%) in 1:128, 14(10.0%) in 1:256, 3(2.1%) in 1:512, 5(3.6%) in 1:1024 and 3(2.1%) in 1:2048. The ranges of positive rate from the sera in each group of breeding-pig farms were 20~61.9%.

• 한국동물위생학회지
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• 제27권1호
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• pp.31-39
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• 2004

This study was performed to investigate the rabies surveillance in Gangwon-do from 1997 to 2001. Of 185 laboratory submissions for rabies diagnosis, 65(35.1%) cases were determined to be infected with the rabies virus. Annual incidence of animal rabies was 10 cases in 1997, 20 cases in 1998, 16 cases in 1999, 3 cases in 2000, and 16 cases in 2001, respectively. The total number of the reported cases were increased 382% compared with that of the previous period from 1993 to 1996(7 cases). The relative contributions of infected animals in this period were as follows: cattles(24 cases), dogs(26 cases), and raccoons(15 cases). Rabies outbreak in raccoon were steadily expanded. Epidemiologic surveillance showed the rabies outbreaks spreaded to the southern area in Gangwon-do. All rabies cases were showed positive results to rabies tests such as clinical signs, histopathological findings, indirect flourescent antibody test, and mouse inoculation test. Further studies such as genetic and phylogenetic analysis of the isolates should be performed in order to figure out accurate rabies outbreak.

• 대한임상검사과학회지
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• 제43권1호
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• pp.26-31
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• 2011

The genotypes of Human Papilloma Virus (HPV) are important in the carcinogenesis of uterine cervical cancer. Diagnosis of uterine cervical cancer screening has been executed using Papanicolau method (Pap) and HPV DNA Chip method. We researched the interrelation of HPV DNA genotypes in single and multiple infections and analyzed the results of Pap and HPV DNA Chip tests at Gunsan Medical Center (GMC). The correlation analysis was surveyed on collected results from 599 patients who have been tested with both Pap and HPV DNA chip tests from November 2004 to May 2010 at GMC. The inconsistency between Pap and HPV DNA Chip tests was 41.1%. The HPV DNA Chip genotype related with high risk cases were type 16 (13.5%), type 52 (10.5%), type 58 (10.1%), and type 18 (3.4%). Those related with low risk cases were type 70 (8.9%), type 6 (1.7%), type 40 (1.2%), type 11 (1.3%), and other types (14.3%). Among the 195 cases of HPV positive status, 161 cases were associated with single infection; 108 (67.1%) cases were related with high risk genotype; 19 (11.8%) cases were low risk genotype; 31 (21.1%) cases were related with other types. 29 cases were associated with double infections; 23 (79.3%) cases were high risks; 5 (17.2%) cases were mixed high and low risks; 1 (3.5%) case was low risk.

• 한국대기환경학회지
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• 제15권2호
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• pp.139-150
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• 1999

The ozone concentrations measured at the National Air Monitoring Stations between 1990 and 1995 were reviewed to detect any anomalies in the measurements. By screening the cases, in which variation of the ozone concentration from the previous measured value is greater than 75ppb, 125 station-days were identified as the test cases for the anomaly test. Historical and parallel consistencies of the measured concentrations were examined by plotting data for each test case. The detected anomalies can be classified into four categories; single outliers, anomalous variations during the startup period, baseline rises, and fluctuations in th diurnal variations. Anomalies were detected in as many as 80 cases among 125 test cases. Because of these anomalies, the number of hours exceeding 100ppb in the areas other than the Greater Seoul Area(GSA) could decrease from 157 to 107. Further studies for developing the methodology for eliminating the abnormal monitoring data are warranted for the data from the National Air Monitoring Stations are official to the both inside and outside of the country.

• 농촌의학ㆍ지역보건
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• 제12권1호
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• pp.117-123
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• 1987

Detection of IgG antibody in clonorchiasis has been accomplished through various serodiagnostic procedure including complement fixation test, gel diffusion test, indirect fluorescent antibody test, indirect hemagglutination test etc. In this report enzyme immunoassay (ELISA) and indirect hemagglutination test (IHA) were used to determine IgG serum antibody levels before and after therapy with praziquantel. Briefly, sera from 62 cases of confirmed human clonorchiasis were examined before and after treatment with praziquantel. Among 62 cases treated 25 cases were categorized as completely cured groups by formalin-ether and careful examination of 4 cellophane thick smered slides at 18 months after treatment. The sera of 25 cases of cured groups were examined again by ELISA and IHA, and com-pared to the previous data. The results obtained were as follows; 1) Sensitivity of IHA test was 83.6% when cut-off titer of 1:8 was applied. No sera obtained from 10 normal healthy control showed positive reaction. 2) Twenty cases (80.0%) out of 25 cured one showed negative results by IHA at 18 months after treatment. 3) Although 5 cases showed positive titer even 18 months after treatment 3 cases of them showed decreased antibody titer. However 2 cases did not show any response. 4) Even though almost all cases showed de- creased ELISA value, only 11 cases (44.0%) out of 25 patients showed negative results by ELISA at 18 months after treatment. In conclusion, it is suggested that, while IgG ELISA for detecting long persisting antibody was more sensitive than IHA, IHA results more conclusively indicated effective treatment in clonorchiasis by negative conversion than did the results of ELISA.

• 한국정보과학회논문지:소프트웨어및응용
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• 제41권7호
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• pp.469-480
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• 2014

소프트웨어 제품라인은 제품들 간의 공통성 및 가변성을 전체 개발라이프사이클에 걸쳐 체계적으로 계획하고 재사용하여 생산성 향상, 비용절감, 시장적시성 향상을 꾀하는 소프트웨어 개발 패러다임이다. 소프트웨어 제품라인이 가져다 주는 이익을 최대화하기 위하여 시험은 도메인 공학과 어플리케이션 공학의 두 라이프사이클을 구성하는 프로세스들과 일관된 방식으로 통합되어야 하며, 더불어 시험 노력을 절감할 수 있어야 한다. 본 논문에서는 조합 시험 설계를 적용하여 제품라인 플랫폼을 시험할 시험항목을 생성함으로써 시험항목 개수를 상당히 줄이면서 동시에 재사용이 용이한 시험항목 생성을 지원하여 시험노력을 절감할 수 있는 조합 시험 설계를 이용한 제품라인 시험항목 생성 방법을 제안한다. 또한, 사례연구를 통하여 제안한 방법이 조합 설계를 이용하거나 그렇지 않은 기존의 다른 방법들 보다 효율적임을 보인다.

• Journal of Information Processing Systems
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• 제6권2호
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• pp.235-252
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• 2010

Regression testing is a very costly process performed primarily as a software maintenance activity. It is the process of retesting the modified parts of the software and ensuring that no new errors have been introduced into previously tested source code due to these modifications. A regression test selection technique selects an appropriate number of test cases from a test suite that might expose a fault in the modified program. In this paper, we propose both a regression test selection and prioritization technique. We implemented our regression test selection technique and demonstrated in two case studies that our technique is effective regarding selecting and prioritizing test cases. The results show that our technique may significantly reduce the number of test cases and thus the cost and resources for performing regression testing on modified software.

• 한국정보과학회논문지:소프트웨어및응용
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• 제36권9호
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• pp.697-705
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• 2009

GUI 테스트의 자동화는 크게 두 가지로 분류하여 생각해 볼 수 있다. 즉, 회귀 테스트 (Regression Test) 자동화와 테스트 자동화(Automated Test)이다 전자는 테스트 케이스를 수동으로 생성하고 수행만을 자동화하는 의미를 가지는 반면, 후자는 테스트 케이스 생성 자체의 자동화도 포함한다. 점차 테스트에 소요되는 비용이 커지는 상황에서 테스트 자동화 방안을 계속적으로 모색하고 있으나 실제 적용되는 방법은 대부분 회귀 테스트에 한정되어 있다. 즉, 테스트를 처음 수행하는 단계에서는 직접 테스트 케이스를 생성하는 작업이 요구된다. 관련하여 기존의 많은 연구들이 상태 전이도를 기반으로 테스트 케이스를 자동으로 생성하는 방안을 제안하고 있으나 이 방법 역시 사람이 상태 전이도를 작성해야하는 문제를 남기게 된다. 본 논문에서는 자동화 범위를 보다 확대하여 소스코드를 기반으로 테스트 케이스를 자동으로 생성하고 수행하는 방안을 소개한다. 논문에서는 디지털 텔레비전에 탑재되는 셋탑 박스 기반의 어플리케이션 프로그램을 대상으로 연구하였으며 기존에 필요했던 수작업이 없이도 테스트 자동화를 진행하는 것이 가능하다는 것을 실제 적용 사례로 제시하였다. 물론 본 연구결과를 아직 일반화하여 적용할 수는 없을 것이다. 그러나 기존의 테스트 자동화 기법 및 연구들과 비교하여 본 연구결과는 수작업의 양을 보다 줄일 수 있었고 이후 완전한 테스트 자동화 또한 가능하다는 것을 보였다는데 그 의의가 있을 것이다.

• Pediatric Infection and Vaccine
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• 제9권1호
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• pp.85-94
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• 2002

목 적 : 호흡기 감염증으로 입원한 어린이에서 Mycoplasma pneumoniae(M. pneumoniae) 항체검사와 polymerase chain reaction(PCR)를 실시하여 항체 양성율과 항체 역가와 PCR과의 연관성 및 항체 검사와 PCR법으로 M. pneumoniae 감염으로 진단된 어린이의 흉부 x-선 소견의 특징을 밝히고자 하였다. 방 법 : 2000년 1월부터 2001년 12월까지 원광대학교병원 소아과에 호흡기 감염증으로 입원한 어린이 1979명을 대상으로 M. pneumoniae에 대한 항체검사를 시행하였고 항체가가 1 : 80 이상을 양성으로 하였으며, 이들 중 무작위로 추출된 131 명 환아의 객담에서 PCR을 이용한 검사를 시행하였다. 이들 검사결과 M. pneumoniae 감염으로 진단했던 예에서 흉부 x-선 소견의 양상을 분석하였다. 결 과 : 총 대상 환아중 항체가가 1 : 80 이상으로 양성을 보인 어린이는 499례(25%)이었다. PCR 검사를 시행한 131례 중 86례(66%)에서 음성이었으며 45례(34%)에서 양성이었다. PCR 음성인 86례 중 54례(63%)에서 항체검사 역시 음성이었으며 항체가 1 : 80 이상인 경우는 32례(37%)이었다. PCR 양성인 45례 중 36에서 항체 검사가 양성이었으며 9례는 음성이었다. Mycoplasma 감염으로 진단된 400례 전례에서 객담 그람염색과 일반 세균배양 검사에서 음성이었다. 항체검사 양성인 환아 가운데 흉부 x-선 검사에서 가장 흔한 소견은 간질성 폐침윤으로 266례(53%)이었고 22례(4%)에서 늑막 삼출소견을 보였으며, 129례(26%)에서는 정상 x-선 소견을 보였다. PCR 검사 양성인 45례 가운데 간질성 폐침윤은 32례(71%)이었고 x-선 소견에서 이상을 발견 할 수 없는 경우는 4례(8%)이었다. 결 론 : 호흡기 감염증을 보인 어린이에서 M. pneumoniae 감염에 의한 펴냄의 진단은 PCR 양성인 경우 항체검사 양성율이 높아서 M. pneumoniae에 대한 PCR이 진단에 유용하며, 항체에 양성이며 흉부 x-선 소견은 정상인 예가 적지 않아서 상기도 감염증의 어린이에서 M. pneumoniae 감염이 다소 흔할 것으로 추정된다.

• Journal of Genetic Medicine
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• 제12권2호
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• pp.96-99
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• 2015

Purpose: To evaluate the performance of the Momguard noninvasive prenatal test by tracing the 'screen positive' results based on preliminary samples from Korean cohorts. Materials and Methods: This preliminary study is based on data collected by the LabGenomics Clinical Laboratory (Seongnam, Korea) with informed consent. Only pregnant women who underwent both the Momguard test and karyotyping were included in this study. Momguard test results were compared with those of the karyotyping analysis. Results: Among the 38 cases with 'screen positive' results by Momguard, 30 cases also had karyotyping results available. In three trisomy (T) 18 and three T13 cases, the Momguard results were concordant with the karyotyping results. For the T21 cases, except for one case belonging to the mid-risk zone, Momguard results from 23 out of 24 cases matched the karyotyping results. Conclusion: Momguard is a highly reliable screening tool for detecting T13, T18, and T21 cases in independent Korean cohort samples.