• Journal of Pharmaceutical Investigation
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• v.36 no.4
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• pp.245-251
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• 2006

The novel microsphere blending and multiple emulsion method by single process was tried to prepare sustained release microspheres which release a physiologically active substance for long periods of time. A drug was separately dissolved in each of two or more oils containing biodegradable polymers to give the primary oil phases. The primary oil phases were dispersed in single aqueous phase in succession. From the drug-dispersed solution, the organic solvent was removed to produce microspheres. The accelerated drug release from the microsphere formulation prepared by single process through the multiple emulsion method was very similar to a physical blending of separately prepared microspheres using the same polymers. But long term release was not same. In this study, leuprorelin acetate loaded poly(lactide-co-glycolide) microsphere formulation for one-month delivery was developed by the multi-emulsion method followed by solvent extraction/evaporation method.

• Proceedings of the Korean Geotechical Society Conference
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• 2009.03a
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• pp.265-277
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• 2009

A long-term field demonstration experiment of selected stabilization method to reduce the heavy metal mobility in farmland soil contaminated by heavy metals around abandoned mine site was conducted. Field demonstration experiments were established on the contaminated farmland with the wooden plate(thickness=1cm) which dimension were width=200cm, Length=200cm, height=80cm and filled with treated soil, which was mixed with lime stone and steel refining slag except on control plot. Soil samples were collected and analyzed during the experiment period(2008. 2~2008. 8) after the installation of the plots. Field demonstration experiments results showed that the application ratio of lime stone 5% was effective for immobilizing heavy metal components in contaminated farmland soil.

• Journal of Ginseng Research
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• v.22 no.2
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• pp.82-90
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• 1998

In order to stabilize the price of fresh ginseng by extension of seasonal variation and marketing structure, and to reduce the cost of production by works of intensive and short term, studies were carried out. As fresh ginseng of 4 years old by the MA and CA was stored for 12 week at 4$^{\circ}C$, samples were collected after every 1, 2, 3, 4, 6, 8, 12 weeks for processing red ginseng. Color and Sensual characteristics on ginseng steamed red for the quality evaluation are summarized as follows. For the time course of storage with red ginseng, which was processed from fresh one after various treatments, L and b values were decreased, however a value was increased. In particular, absorbance was step-wisely increased. Turbidity was somewhat increased, and non-treatment of preservative were shown 2 times higher of absorbance. Extraction ratio of ethanol-soluble extractives slightly increased by the preservation methods, and as storage period was passed. CA storage and preservative treat merit versus MA and non-preservative treatment gave much stability in ginseng quality. In the sensual characters, sour taste and sweet taste were increased, but fresh taste and rice scorched taste were decreased. Bitter taste was not much changed until end of storage. CA was shown smaller differences than MA in the pH change. Addition of preservative extended the storage time.

• Journal of the Korea Society of Computer and Information
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• v.4 no.4
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• pp.77-85
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• 1999

In this paper. improved the formula of Kass. First of all, improved initial guess inside and outside of an object. So, prevent the of shrink, find more easily and faster the contour of object. Secondly, proposed the algorithm which moved to local minimum with the improvement of formula of the internal energy and $3{times}3$ matrix. Process the noise of local minimum with use of medial filtering. In third, process the phenomenon which edge points gather one point with imposing energy to the energy term. Improve the algorithm to find the contour precisely with the use of threshold. The result of these improvements, make an initial guess easily and find the contour of objects which have higher curvature. Improve the speed of process by reducing the repetition of feedback system.

• Transactions of the Korean Society of Mechanical Engineers
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• v.19 no.1
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• pp.45-60
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• 1995

It is attempted to estimate excitation force of a linear vibratory system using measured vibration responses. The excitation force is estimated from the relationship between the vibration response and system characteristic matrices which are extracted from both the mathematical model of the system and actual response in contrast to the usual approach of inverting the frequency response matrices. This extraction scheme is based on the fact that the vibration response can be expressed in term of linear combination of frequency domain modal vectors defined as mutually orthonormal basis vectors in frequency domain. The extracted frequency domain basis vectors are very stable in computational manipulation. It is found that the estimated excitation force is in good agreement with actually measured force except at the natural frequencies the structure, which is the common feature still to be overcome by the research efforts in this area. From the results of this paper, this disagreement is considered to come from the discrepancy between the model and actual value of the mass, damping and stiffness of the structure.

• Journal of Periodontal and Implant Science
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• v.36 no.1
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• pp.61-68
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• 2006

The factors influencing long-term prognosis of teeth must be carefully considered. Among these, attachment level is strongly associated with tooth loss. The purpose of the present study was to estimate pattern of attachment loss based on attachment area in extracted teeth. 197 satisfied the criteria for assessment after staining. The protocol described by Waerhaug(l975) was performed. An indir ect method, based on digital image abstracted from digital camera and digital imaging software program, was used to calculate the root surface area and the attachment loss area. The data were analysed using SPSS. Except maxillary central incisior and mandibular canine, no statistical significant differences between each root surfaces were observed in anterior teeth. In posterior teeth, statistical significant differences in palatal surface of maxillary molar and mandibular molar compared with others were observed. Statistical significant difference in buccal surface compared with others was lowly observed in single and multi rooted. This study did not reveal progressive loss pattern of attachment area in each root surface but clarified root surface that has relative high loss rate of attachment area at extraction. Thus understanding this pattern of attachment loss is helpful for dentist to treat the periodontitis.

• Journal of the Korean Society of Food Science and Nutrition
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• v.23 no.2
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• pp.225-231
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• 1994

As the way of mass process of red pepper, extraction of oleoresin, which is labile during distribtuion and long-term storage, is alternative way to minimize markdown of red pepper quality. Changes of carotenoid pigments in modified oleoresin during cooking at high temperature were investigated. Dried red peperwas milled to 100 mesh of size particle and oily compounds were extracted by reduced pressure steam distillation. The rest part was reetracted and concentrated. The extracts were combined . The same volume of water and 4 % of polyglycerol condensed ricinoleate (PGDR) were added to the combined extract, and emulsified to make oleroesin. Capsanthin among dried red pepper, was the most abundant carotenoid (97.80mg%) followed by $\beta$ -cartoene, cryptoxanghin ,violaxanthin, crypotocapsin, and capsorubin. Oleoresin is acquiesce in the same order of raw red pepper. Transmittal of color components from raw red pepper to oleroresin was over 85% in cryptoxanthin, crytocapsin, and $\beta$ -carotene, over 70% in capsolutein and hydroxycapsolutein, and under 50% in antheraxanthin and mutatoxanthi Crytocapsin cryptoxanthin, an capsorubin in oleoresin red pepper were remained 72.1, 51.8 and 25.25, respectively, after cooking for 5hours at10$0^{\circ}C$. Color compounds were unsteady by cooking , About 90% of color compounds were destroyed by 3 hours cooking at 15$0^{\circ}C$. But, they were more thermostable under nitrogen circumstance than air one.

• Proceedings of the Korean Geotechical Society Conference
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• 2009.09a
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• pp.1487-1506
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• 2009

A long-term field experiment of the selected stabilization methods(Cover system, full range and upper range treatment) was conducted to reduce the heavy metal mobility in farmland soil which was contaminated by heavy metals around abandoned mine site. Field experiments were established on the contaminated farmland with the wooden plate and filled with treated soil, which was mixed with lime stone and steel reforming slag except on control plot. Soil samples were collected and analyzed during the experiment period(about 4 months) after the installation of the plots. Field demonstration experiments results showed that the cover system and the full range treatment of the selected stabilization methods applied to the application ratio of lime stone 5% and steel refining slag 2% were effective for immobilizing heavy metal components in contaminated farmland soil.

• Proceedings of the Korean Geotechical Society Conference
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• 2009.09a
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• pp.1455-1471
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• 2009

In order to investigate on the effect of stabilization methods for rice paddies contaminated by heavy metals, a series of lab-scale model test was carried out by applying the characteristics of submerged Paddy soil. To perform the lab-scale model test, columns were made by acrylic with the dimension of diameter=10cm, thickness=0.5cm and were filled with soils which was contaminated were mixed with stabilization agents(lime stone 5% and steel refining slag 5% respectively). To manipulate the reduction condition, soils in the columns were submerged with distilled water. And then soil water and subsurface water in each column were sampled in the regular term and analysed the various physical and chemical properties.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.65 no.3
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• pp.388-396
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• 2016

Through the correspondence works with international electrotechnical vocabulary(IEV) in the smart grid field and power information technology field, we analyzed cases for discussion of terms and definitions in the IEV and then proposed an advanced procedure and computing system for standardization of International Electronical Committee(IEC) terminologies. The standardization procedure consists of processes for existing terminology, new terminology and correspondent terminology which have different structures. An example of the standardization work of correspondent terminology is given. The standardization computing system are based on the process for terminology extraction, terminology verification and terminology management which could provide the Wikipedia type terminology search function. In order to prevent that there exist multiple terminologies in IEV, the database search system is needed to be developed. We proposed the 'IEV_Term_Search' program which is the database search system. Terminology standardization of different technical committees(TC) and completion of the IEV to promote cooperation between TC 1 and the TCs must be followed by revision and standardization using the standardization computing system.