• Investigative Magnetic Resonance Imaging
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• v.23 no.2
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• pp.114-124
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• 2019

Purpose: We investigate biases in the assessments of left ventricular function (LVF), by compressed sensing (CS)-cine magnetic resonance imaging (MRI). Materials and Methods: Cardiovascular cine images with short axis view, were obtained for 8 volunteers without CS. LVFs were assessed with subsampled data, with compression factors (CF) of 2, 3, 4, and 8. A semi-automatic segmentation program was used, for the assessment. The assessments by 3 CS methods (ITSC, FOCUSS, and view sharing (VS)), were compared to those without CS. Bland-Altman analysis and paired t-test were used, for comparison. In addition, real-time CS-cine imaging was also performed, with CF of 2, 3, 4, and 8 for the same volunteers. Assessments of LVF were similarly made, for CS data. A fixed compensation technique is suggested, to reduce the bias. Results: The assessment of LVF by CS-cine, includes bias and random noise. Bias appeared much larger than random noise. Median of end-diastolic volume (EDV) with CS-cine (ITSC or FOCUSS) appeared -1.4% to -7.1% smaller, compared to that of standard cine, depending on CF from (2 to 8). End-systolic volume (ESV) appeared +1.6% to +14.3% larger, stroke volume (SV), -2.4% to -16.4% smaller, and ejection fraction (EF), -1.1% to -9.2% smaller, with P < 0.05. Bias was reduced from -5.6% to -1.8% for EF, by compensation applied to real-time CS-cine (CF = 8). Conclusion: Loss of temporal resolution by adopting missing data from nearby cardiac frames, causes an underestimation for EDV, and an overestimation for ESV, resulting in underestimations for SV and EF. The bias is not random. Thus it should be removed or reduced for better diagnosis. A fixed compensation is suggested, to reduce bias in the assessment of LVF.

• Korean Journal of Ecology and Environment
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• v.45 no.4
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• pp.378-391
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• 2012

The objective of this study was to determine temporal patterns and longitudinal gradients of water chemistry at eight artificial reservoirs and ten streams within the Han-River watershed along the main axis of the headwaters to the downstreams during 2009~2010. Also, we evaluated chemical relations and their variations among major trophic variables such as total nitrogen (TN), total phosphorus (TP), and chlorophyll-a (CHL-a) and determined intense summer monsoon and annual precipitation effects on algal growth using empirical regression model. Stream water quality of TN, TP, and other parameters degradated toward the downstreams, and especially was largely impacted by point-sources of wastewater disposal plants near Jungrang Stream. In contrast, summer river runoff and rainwater improved the stream water quality of TP, TN, and ionic contents, measured as conductivity (EC) in the downstream reach. Empirical linear regression models of log-transformed CHL-a against log-transformed TN, TP, and TN : TP mass ratios in five reservoirs indicated that the variation of TP accounted 33.8% ($R^2$=0.338, p<0.001, slope=0.710) in the variation of CHL and the variation of TN accounted only 21.4% ($R^2$=0.214, p<0.001) in the CHL-a. Overall, our study suggests that, primary productions, estimated as CHL-a, were more determined by ambient phosphorus loading rather than nitrogen in the lentic systems of artificial reservoirs, and the stream water quality as lotic ecosystems were more influenced by a point-source locations of tributary streams and intense seasonal rainfall rather than a presence of artificial dam reservoirs along the main axis of the watershed.

• Ocean and Polar Research
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• v.42 no.2
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• pp.115-131
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• 2020

The effective range of surface current data observed by high-frequency radar (HFR) operated in the northern coastal area of Jeju Island by Korea Institute of Ocean Science and Technology was estimated and the distribution and variability of the M₂ tidal current of the Jeju Strait was analyzed. To evaluate the HFR data, the M₂ tidal current corrected from 25 hours current data observed by the Korea Hydrographic and Oceanographic Agency (KHOA) was compared with the M₂ tidal current in the Jeju Strait analyzed from the surface currents of HFR. The reliability of HFR data was confirmed by analyzing the characteristics of the tide components of these two data sets, and the effective range of HFR data was estimated through temporal and spatial analysis. The observation periods of HFR used in the analysis were from 2012 to 2014, and it was confirmed that there is a difference in the effective range of HFR data according to the observation time. During the analysis periods, the difference between the M₂ current ellipses from the data of KHOA and the HFR was greater in the eastern than in the western part of the Jeju Strait, and represented a high reliability in the western and central parts of the Jeju Strait. The tidal current of the Jeju Strait analyzed using the HFR data revealed a seasonal variability a relatively weak in summer and a strong in winter, about a 17% fluctuations between the summer and winter based on the length of the semi-major axis of tidal ellipse. Appraisals and results of regarding the characteristics and seasonal variability of the M₂ tidal current in the Jeju Strait using HFR data have not been previously reported, so the results of this study are considered meaningful.

• Childhood Kidney Diseases
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• v.3 no.2
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• pp.109-116
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• 1999

Purpose: Insulin-like growth factor(IGF)-I and -II are peptide growth factor whose activity is modulated by interaction with the family of six IGF-binding proteins(IGFBPs). IGF-I is detected in rat kidney and has metabolic and growth effects. This study was designed to examine temporal expression of IGFBPs in kidney during renal development and postischemic regeneration in rat. Method: The expression of IGFBPs in kidney during renal development from 15th day of gestation to adult life by using Northern blot analysis. We also examined the renal IGF-IGFBP axis in uremic rat by using Northern blot and immunohistochemistry. Results: The mRNA of IGFBP-1 and -3 were not or barely detected in fetal stages. However, the mRNA level of IGFBP-1 and -3 were increased gradually from day 7 after birth to adult. In contrast, the mRNA of IGFBP-2 and -5 were highly expressed in fetal stages and maintained almost same levels until day 7 (IGFBP-2) or day 30 (IGFBP-5) after birth, then their levels decreased markedly. The mRNA of IGFBP-4 were expressed moderately in fetal kidney and increased gradually after birth. Interestingly, the mRNA of IGFBP-1 and-4 were induced up to 3-5 fold during maximum regeneration period and were recovered to normal levels after acute ischemic injury. In contrast, the mRNA level of IGFBP-3 and-IGFBPrP-1 were decreased slightly at 1 day after ischemic injury, then recovered to normal level during maximum regeneration period. Conclusion: There were differential expressions of IGFBPs in kidney that can modulate IGF action on developing, differentiating, maintaining, and regenerating renal structure and function.

• Journal of the Institute of Electronics Engineers of Korea CI
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• v.37 no.1
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• pp.55-63
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• 2000

This paper investigated the sub-region compression effect of the three dimensional DCT(3D-DCT) using the difference component(DC) of inter-frame in images. The proposed algorithm are the method that obtain compression effect to divide the information into subband after 3D-DCT, the data appear the type of cubic block(8${\times}$8${\times}$8) in eight difference components per unit. In the frequence domain that transform the eight differential component frames into eight DCT frames with components of both spatial and temporal frequencies of inter-frame, the image data are divided into frame component(8${\times}$8 block) of time-axis direction into 4${\times}$4 sub block in order to effectively obtain compression data because image components are concentrate in corner region with low-frequency of cubic block. Here, using the weight of sub block, we progressed compression ratio as consider to adaptive sub-region of low frequency part. In simulation, we estimated compression ratio, reconstructed image resolution(PSNR) with the simpler image and the complex image contained the higher frequency component. In the result, we could obtain the high compression effect of 30.36dB(average value in the complex-image) and 34.75dB(average value in the simple-image) in compression range of 0.04~0.05bpp.

• Journal of Veterinary Clinics
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• v.29 no.4
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• pp.344-347
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• 2012

Bilateral convergent strabismus with exophthalmus(BCSE) is an eye disorder affecting many cattle breeds worldwide. BCSE is the most common in cattle at various types of strabismus. Divergent strabismus is of relatively low incidence than convergent strabismus. This report is the to shown a case of convergent and divergent strabismus with unilateral in the exophthalmus in a heifer Holstein cow. A female Holstein calf born with congenital progressive divergent strabismus in right eye and convergent strabismus in left eye was tested. Ocular and blood examination, and activity were checked from the first week, 8 month, and 16 month after birth. The ocular examination includes general inspection, fixation reflex and menace response. The general inspection is checking the degree of deviation of both eyes from the normal visual axis, which was determined by the amount of sclera permanently visible in the temporal corner of the eye. The stage is divided into 4 stages depending on the degree of deviation. The right eye shown in stage 4 continues after birth and the left eye shown stage 2, stage 3 and stage 4 at 1 week, 8 month and 16 month after birth, respectively. In fixation reflex and Menace response, both eye balls showed a normal response at 1 week, 8 month and 16 month after birth. Blood count and serum chemistry test were performed, but a specific factor was not detected outside the reference range.

• The korean journal of orthodontics
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• v.36 no.3 s.116
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• pp.218-227
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• 2006

Although the submentovertex radiograph and surface EMG are not often used due to the difficulty of interpretation, they are accepted as useful diagnostic and analytic aids for skeletal asymmetry. There have been reports which state that they were also useful for the evaluation of vertical skeletal relations. The purpose of this study was to evaluate the correlations between EMG data, measurements from submentovertex radiographs, facial types and facial asymmetry following examination of 60 asymmetric patients. The radiographic corpus length were greater in the nonaffected sides (p<0.001), gonion to interspinosum axis were greater in the affected sides and the mandibular condyle and gonion were located more anteriorly in the non-affected sides than in the affected sides but not significant (p=0.07). The activity of the anterior temporal muscle in rest position was higher in the affected sides than in the non-affected sides (p<0.01). The activity of the masseter muscle at maximum clenching was found to be nonsignificant but it was higher in the affected sides than in the non-affected sides (p=0.09). There was positive correlation between facial index and the intercondylar axes angle (p<0.01). There was positive correlation between masseter muscle activity in maximum occlusion and facial index in the affected and non-affected sides (p<0.05). The results demonstrate that the submentovertex radiograph and EMG can provide useful information for the evaluation of horizontal and vertical skeletal relations.

• The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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• v.8 no.2
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• pp.94-110
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• 2003

This study utilizes the dataset of Topex/Poseidon(T/P) altimeter sea surface height (1992-2000 yr., 286 cycles)to investigate the tempore-spatial variability in the East (Japan) Sea. Optimal interpolation (Ol) technique was applied to the pre-processed T/P dataset (level 2) to produce sea surface height anomaly (SSHA) map on regular grids. Spectral analyses of the timeseries of the SSHA at chosen stations and empirical orthogonal function (EOF) analysis of the SSHA in the entire East Sea were made. Distribution of the SSHA can be divided by the southern and northern regions sharply by the polar front situated in the middle of the East Sea. The southern region under the direct influence of the Tsushima Current exhibits higher amplitude of the SSHA fluctuation, while the northern region does relatively smaller one. The spatio-temporal variability of the SSHA in the East Sea can be characterized by the five modes of the EOFs accounting for more than 85% of the total variance. The first mode dominates the SSHA variation in the entire domain with strong seasonal and inter-annual periods accounting for the 72.3% of the total variance. The other modes (up to 5th account for 14%) are responsible for the SSHA variation associated with the local current system, meandering of the polar frontal axis, and mesoscale eddies. Spectral peaks with significant confluence level show semi-annual, annual and interannual (2, 3-4 years) periods.

• The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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• v.23 no.1
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• pp.32-48
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• 2018

The mechanisms of $CH_4$ uptake into and release from the ocean are not well understood due mainly to complexity of the biogeochemical cycle and to lack of regional-scale and/or process-scale observations in the marine boundary layers. Without complete understanding of oceanic mechanisms to control the carbon balance and cycles on a various spatial and temporal scales, however, it is difficult to predict future perturbation of oceanic carbon levels and its influence on the global and regional climates. High frequency, high precision continuous measurements for carbon isotopic compositions from dissolved $CH_4$ in the surface ocean and marine atmosphere can provide additional information about the flux pathways and production/consumption processes occurring in the boundary of two large reservoirs. This paper introduces recent advances on optical instruments for real time $CH_4$ isotope analysis to diagnose potential applications for in situ, continuous measurements of carbon isotopic composition of dissolved $CH_4$. Commercially available, three laser absorption spectrometers - quantum cascade laser spectroscopy (QCLAS), off-axis integrated cavity output spectrometer (OA-ICOS), and cavity ring-down spectrometer (CRDS) are discussed in comparison with the conventional isotope ratio mass spectrometry (IRMS). Details of functioning and performance of a CRDS isotope instrument for atmospheric ${\delta}^{13}C-CH_4$ are also given, showing its capability to detect localized methane emission sources.

• Journal of Environmental Impact Assessment
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• v.21 no.3
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• pp.483-501
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• 2012

The purpose of this study was to apply a multi-metric model of Lentic Ecosystem Health Assessments(LEHA) for environmental impact assessments of Cheongpyung Reservoir during 2005 - 2006 and assessed the ecological model values. The ecosystem model of LEHA was composed of eleven metrics such as biological parameters($B_p$), physical parameters($P_p$), and chemical parameters($C_p$), and determined the rank of ecological health by the criteria. The variables of $B_p$ were metrics of % sensitive species($M_2$, NMS) and insectivore species($M_5$, % $I_n$), which decrease as the water quality degradates, and these metric values were low as 1.5% and 32.4%, respectively. In contrast, the proportions of tolerant species and omnivore species as the other $B_p$ parameters were 43% and 62%, respectively, which indicate a degradation and disturbance of the ecosystem. Riparian vegetation coverage($M_9$, % $V_c$) as a variable of $P_p$, were higher in the 2nd than 1st survey, and decreased toward the dam site from the headwaters. This was due to a habitat simplification(modifications) by frequent bottom dredging of sand and rocks. The variables of $C_p$ were two metrics of specific conductivity($M_{10}$, $C_I$) as an indicator of ionic contents(cations and anions) and the Trophic State Index(TSI) based on chlorophyll-a($M_{11}$, $TSI_{CHL}$) as an indicator of trophic state. These metric values of $C_p$ had high temporal variations, but low spatial variations on the main axis of the reservoir along with the ecological health of a good condition. The environmental impact assessments using the LEHA multi-metric model indicated that the model values of LEHA averaged 30.7 in 1st survey(fair - poor condition) vs. 28 in 2nd survey(poor condition), indicating a temporal variation of the ecological health. The model values of LEHA showed a minimum(28) in the lacustrine zone(S5) and ranged from 29 to 30 in the other locations sampled, indicating a low longitudinal variation. Overall, environmental impact assessments, based on LEHA model, suggest that chemical water quality conditions were in good, but biological conditions were disturbed due to habitat modifications by frequent dredgings in the system.