• Journal of Animal Science and Technology
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• 제60권4호
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• pp.7.1-7.5
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• 2018

Background: Mice are widely accepted research models of great clinical significance. Maintenance of laboratory mice breed is an essential aspect for performing research activities in various fields of science. Infanticide is one of the prominent causes of litter loss during maintenance of laboratory mice stock. The present study is an effort to monitor the effect of change in ambient temperature of female mice below the normal range on cannibalism and infanticide during early postparturition phase. Adult female Swiss albino mice have been divided into two groups of control and treatment. On the day of litter group one was maintained under controlled temperature conditions (minimum $20^{\circ}C$ to maximum $23^{\circ}C$) throughout, while female mice belong to group two have been exposed to variation of room temperature (maximum $15^{\circ}C$ to minimum $10^{\circ}C$ for two nights and one day) until 36 h postparturition. Results: The effects of temperature changes were observed on the infanticide behaviour of dams along with the survival of pups in early postparturition phase till 36 h after delivery. The significant statistical difference (P < 0.05) was reported in infanticide behaviour of dams when control and treatment group was compared. It is observed that decrement in surrounding temperature promotes decrement in the ambient body temperature of dams during early postparturition. It is proposed that alteration of hypothalamic homeostasis due to temperature change induces cannibalism and infanticide behaviour. Lack of thermoregulation during early postparturition creates the sense of insecurity, in-satiety, anxiety and stress. Conclusions: Authors strongly recommend the maintenance of body and surrounding temperature to prevent infanticidal behaviour and cannibalism within Swiss albino mice population. Further investigations are advisable to authenticate the active behavioural and biochemical pathway behind the phenomena.

• 대한안전경영과학회지
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• 제14권3호
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• pp.101-109
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• 2012

It is commonly recognized that railway is one of the representative transportation and it offers public service based on strategies for being rapid, automation, safety. Since the opening of high speed railway, 3-hundred-million people have used it and acknowledged its efficiency. However, derailed accident at Kwangmyeong station in February, 2011, frequent malfunction of KTX-Sancheon, and accidents by engineer's careless fault damaged on credibility of safety, Especially, spreaded accidents through social networking service by cell phones amplified anxiety of public, being criticized by the press. This study analyzed statistics of past accident and cases of passing-by accident, and surveyed 152 KTX captain engineers about their recognition of the accident by careless fault and experiences of possibility of occurrence for preventing engineer's careless fault and restoring trust According to the analysis, engineers worry about responsibility and disadvantages related to the accidents for the most, and they are nervous about malfunction for the second most. This study presents prevention methods regarding the result. First, it is required to improve mental stability and concentration on their work, secondly, advanced ability to cope with malfunction or error through repetitive education and training are required to increase confidence, and for the last, improvement of operational supporting system such as ATP, GPS to prevent errors by human factors. Improvement of the system is expected to lead engineers to prevent careless fault and regain the reputation of railway.

• 문화기술의 융합
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• 제6권1호
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• pp.191-199
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• 2020

본 연구에서는 결혼이주여성이 경험하는 정서경험에 대해 심층적으로 탐구하고자 하였다. 이를 위해 한국어를 할 수 있는 결혼이주여성 3인을 대상으로 심층면접을 진행하였다. 수집된 자료는 Giorgi의 현상학적 연구방법을 통해 분석하였다. 연구결과, '시부모의 따뜻한 관심으로 안정된 삶을 삼', '남편의 지지로 인해 가정에 충실함', '정서적으로 위로를 받아 보다 안정된 삶을 살게 됨', '하나님의 도우심을 경험함으로 기쁨', '정서적으로 회복되어 남편과 주변 사람들에게 잘함', '정서적 불안으로 인해 가정일이 손에 잡히지 않음', '힘들어 자신과 남편을 원망하고 갈등이 일어남', '분노가 일고 결혼한 것을 후회함'의 8개의 범주가 도출되었다. 결혼이주여성의 정서경험에 대한 연구결과를 통해 결혼이주여성들이 정서적으로 잘 적응하며 살 수 있도록 토대를 마련하였다고 볼 수 있다.

• 한국정보전자통신기술학회논문지
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• 제8권2호
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• pp.133-139
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• 2015

연구의 목적은 지적장애인 생활시설 입소자의 스트레스, 행동지수 요인이 삶의 만족도에 미치는 영향을 분석하고자 한다. 연구대상은 대전광역시 지적장애인 생활시설 지적장애인 200명을 대상으로 2014년 3월 5일부터 9월 22일 까지 설문조사를 실시하였다. 분석방법은 SPSS WIN 18.0, Amos 21.0 프로그램을 사용하여 t-test와 일원변량분석, 확인적 요인분석, 구조방정식을 실시하여 유의수준 5%에서 검증하였다. 연구결과는 첫째는 스트레스가 삶의 만족도에 영향을 미치지 않음을 알 수 있다. 둘째, 행동지수요인이 이용만족도에 영향을 미치지 않음을 알 수 있다. 셋째, 신체증상의 경우에 이용자 만족도에 의하여 삶의 만족도에 영향을 미치는 것을 알 수 있다. 향후 생활시설 지적장애인의 이용만족도와 일상생활 스트레스의 개선에 대한 정책적 기초자료에 활용이 요구된다.

• Archives of Pharmacal Research
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• 제22권2호
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• pp.157-164
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• 1999

LB50016 was characterized as a selective and potent$ 5-HT_{1A}$ receptor agonist and evaluate it anxiolytic and antidepressant activities. It shows high affinity for $ 5-HT_{1A}$receptor, moderate affinity for $\alpha$2 adrenergic and $ 5-HT_{2A}$receptors and no significant affinity for other receptors tested. Hypothermia and increased serum corticosterone level were observed in LB50016-treated rats, which are mediated mostly by post synaptic $ 5-HT_{1A}$ receptor activation. In the mouse forced swim model for depression, LB50016-elicited dose-dependent reductions in immobility time, showing $ED_{50}$ of approximately 3 mg/kg i.p., which was blocked by pretreatment of NAN-190, $ 5-HT_{1A}$antagonist. In face-to-face test for anxiolytic activity in mice, estimated $ED_{50}$ was 2 mg/kg, i.p.. In isolation-induced aggression test with mice, fifty-fold increases in latency to attack were observed at 30 min and last up to 4 h after LB50016 treatment (3 mg/kg, i.p.). Taken together, LB50016-induced pharmacological activities are mediated by activation of $ 5-HT_{1A}$receptors, offering an effective therapeutic candidate in the management of anxiety and depression in humans.

• Journal of Animal Science and Technology
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• 제63권3호
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• pp.651-661
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• 2021

This study aimed to investigate whether breed, sex, and age affected temperament differently (more or less neophobic) in mature horses during a novel object test. The study included Jeju crossbred (n = 12, age = 9.42 ± 4.57 y), Thoroughbred (n = 15, age = 10.73 ± 3.09 y), and Warmblood horses (n = 12, age = 13.08 ± 3.55 y) with the females (n = 22, age = 11.36 ± 4.24 y) and geldings (n = 17, age = 10.65 ± 3.66 y). Jeju crossbreds (Jeju horse × Thoroughbred) are valuable considering their popular usage in Korea, but limited studies have explored temperament of Jeju crossbred horses. A trained experimenter touched the left side of the neck with a white plastic bag (novel object). The test ended when the horse stopped escape response and heart rate (HR) dropped to baseline. Behavioral score and escape duration were measured as behavioral variables. Multiple variables related to HR and heart rate variability (HRV) were measured to reflect emotional state. These included basal HR (BHR), maximum HR (MHR), delay to reach maximum heart rate (Time to MHR), standard deviation of beat-to-beat intervals (SDNN), root mean square of successive differences (RMSSD), and ratio of low to high frequency components of a continuous series of heartbeats (LF/HF). Statistics revealed that Thoroughbreds had significantly higher behavioral scores, and lower RMSSD than Jeju crossbreds (p < 0.05), suggesting greater excitement and fear to the novel object in Thoroughbreds. None of the behavioral or cardiac parameters exhibited sex differences (p < 0.05). Age was negatively correlated with SDNN and RMSSD (p < 0.05), indicating that older horses felt more anxiety to the novelty than younger horses. Thoroughbreds and females had distinct correlations between behavioral and HRV variables in comparison with other groups (p < 0.05), implying that escape duration might be a good indicator of stress, especially in these two groups. These results are expected to improve equine welfare, safety and utility, by providing insights into the temperament of particular horse groups, to better match reactivity levels with specific functions.

• International Journal of Advanced Culture Technology
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• 제8권4호
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• pp.279-286
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• 2020

This study was a phenomenological qualitative research that analyzed the experiences of Korean students studying in Korea after the COVID-19 incident. Participants in this study consisted of 22 international students aged 20 to 40 attending the International Exchange Center at C University. The interview period was from September 10, 2020 to October 10, 2020. Giogi qualitative research method was used to analyze vivid experiences of international students. As a result of the analysis, 26 semantic units, 7 subcomponents were derived. The description of the general structure sentence of phenomenology was a description of the meaning of experience from the perspective of participants, and the context and structure descriptions were integrated. The results of this study showed that: The students who came to Korea to study were concerned about Korea in various ways, but they had to adjust to unexpected changes in education methods, anxious about the unexpected COVID-19 disaster. Participants chose to study in Korea based on existing information, so they felt anxiety, regret, fear, and frustration over sudden changes, but taking online classes helped them learn repeatedly and voluntarily became an experience that suited their learning speed. As commuting time has decreased, they were more opportunities to make money in Korea also. Based on the results of this study, the following is suggested: First, the government should establish systematic online infection prevention measures for international students who have poor Korean language skills in preparation for unexpected disasters. Second, non-face-to-face teaching methods should be prepared with the same weight in the face-to-face teaching methods that have been carried out so far in preparation for unexpected disasters.

• 한국환경보건학회지
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• 제47권1호
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• pp.20-35
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• 2021

Objectives: Waste treatment by incineration is gradually increasing as the emission of harmful substances has decreased owing to developments in incineration technology. However, residents living near incinerators continue to express anxiety regarding the effects on their health. Therefore, we attempted to summarize the health impact of incinerators by comprehensively reviewing the recently reported literature. Methods: Sixty-two epidemiological research papers related to incineration and health effects were selected from the Google Scholar database and analyzed (from between January 2001 and December 2019). Results: When compared to older incinerators, newer incinerators established after 2000 are considered relatively safe in terms of health effects. Nevertheless, there have been some studies that have linked them to various diseases, such as malignant tumors including soft tissue cancer and non-Hodgkin's lymphoma, reproductive disorders, respiratory diseases, and more. In addition, incinerator workers and local residents are considered to be exposed to dioxins and some heavy metals from the incinerator. Since most studies included subjects exposed to older incinerators, it is difficult to apply these results to the health impact assessment of new incinerators. However, it is not appropriate to conclude that new incinerators made with state-of-the-art technology are safe, as chronic environmental diseases caused by hazardous substances tend to appear only after prolonged exposure. Conclusions: In terms of environmental health, it is necessary to continuously monitor the health effects of incinerators. Also, there is a need to develop a research methodology that can minimize various confounders in incineration-related epidemiological study.

• 문화기술의 융합
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• 제7권3호
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• pp.105-113
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• 2021

본 연구는 중년여성 근로자를 대상으로 모바일 앱을 활용한 심뇌혈관질환 예방관리 프로그램 참여 경험에 대한 의미를 파악하기 위해 일대일 심층면담 및 포커스 그룹 인터뷰(Focus Group Interview, FGI)를 실시한 질적 연구이다. 본 연구의 대상자는 일 백화점에서 모바일 앱을 활용하여 심뇌혈관질환 예방프로그램에 참여하고 있는 50세 이상의 여성 근로자 26명을 대상으로 하였다. 연구결과 도출된 참여경험은 '알아가는 것에 대한 즐거움', '상호 우호적 관계의 활성화', '건강에 대한 관심이 나를 관리하게 함', '익숙하지 않은 문화를 받아들임', '어디서나 상담을 받는 듯한 편리함'의 주제가 도출되었다. 이러한 결과를 통해 모바일 앱이 건강행위 실천의지를 향상시키는 것으로 나타났고, 모바일 앱을 설치 시 낯선 프로그램에 대한 불안을 감소하기 위해 안전한 프로그램임을 보증할 수 있는 인증기준이 필요함을 제언한다.

• 한국방사선학회논문지
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• 제15권3호
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• pp.293-299
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• 2021

CT 장치를 이용하여 주기적인 검사를 시행하는 환자의 불가항력적 방사선 피폭을 줄이기 위해 다양한 스캔 파라미터 중 X선의 투과력과 밀접한 관전압의 변화를 통해 환자 선량을 감소시킬 수 있는 스캔 방법을 알아보았다. 실험결과 일반적으로 임상에서 많이 적용하는 120 kVp 대신 100 kVp를 적용하여 스캔 시 CTDI가 약 41 % 감소하였다. 또한 화질 변화정도는 CT value는 1046.1±3.7 HU, Pixel value는 71.4±7.9로 측정되었으며 통계분석결과 큰 차이가 없는 것으로 분석되었다(0.05