• 대한간호학회지
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• 제51권5호
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• pp.505-510
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• 2021

• 벤처창업연구
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• 제11권6호
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• pp.27-37
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• 2016

스타트업 팀은 시장의 비즈니스 기회를 신속하게 포착해야 함은 물론이고 이전에 경험해 보지 못한 다양한 문제들을 해결해야만 한다. 본 연구는 신생 조직이나 팀에서 의사소통 매체의 활용을 통해 지식 공유를 거쳐 팀의 민첩성으로 이어지는 프로세스에 대한 가설을 검증하고 과업 갈등에 따른 차이를 비교하기 위한 연구이다. 의사소통 매체의 활용 측면에서 동시적, 비동시적 매체 사용으로 구분하였고, 지식 공유는 속도와 양으로 나누어 영향을 비교하였다. 그리고 신생 조직의 중요한 성과 변수로서 팀의 민첩성을 종속 변수로 설정하였다. 연구 모형을 통해 의사소통 매체를 사용함으로써 지식 공유가 이루어지며 결과적으로 팀의 민첩성에 영향을 주며, 팀의 과업 갈등의 정도에 따라 의사소통 매체의 활용 정도나 변수들 간 관계에 차이가 있을 것이라는 가설을 제시하였다. 설립된 지 5년 미만의 스타트업 팀 230개를 대상으로 설문조사를 통해 데이터를 수집하고 통계적으로 분석하였다. 분석 결과, 갈등 상황을 고려하지 않은 전체 집단에서, 지식 공유의 속도가 빠르면 지식공유의 양이 증가하고, 지식 공유의 속도와 양이 높으면 민첩성이 높아지는 관계를 확인하였다. 또한, 의사소통 매체는 동시적이건 비동시적이건 간에 모두 지식 공유의 속도에 유의미한 영향을 미치는 것으로 나타났다. 한편, 과업갈등의 정도에 따른 분석에서는, 과업갈등이 높은 집단이 낮은 집단에 비해 매체의 사용, 지식 공유의 속도와 양, 민첩성이 더 높았다. 또한, 매체의 사용, 지식 공유, 민첩성으로 이어지는 프로세스에서도 집단 간 차이를 확인하였다. 이러한 결과에 따라 스타트업 팀의 리더를 위한 시사점을 제시하였다.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2007년도 제38회 하계학술대회
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• pp.731-732
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• 2007

This paper presents the final configuration of test field and test items for the application of IEC 60364-4-44 in Korea. IEC 60364-4-44 provides rules for the protection against the effects of conducted and radiated disturbances on electrical installations. Especially this standard deals with the protection of low voltage facility against the ground fault in the high voltage side of power distribution system. Many countries define the regulations on the use of electrical facilities based on their own power system and technical references which are considered to be suitable for them. The background of circuit of IEC 60364-4-44 is based on the ungrounded system as most of European countries. However, domestic electric power distribution system is based on multi-grounding system different from European system. Therefore, it is necessary to evaluate or prove the effect of the IEC 60364-4-44 for introducing and applying it to the domestic grounding system as a national standard. The authors with KEA(Korea Electric Association) carried out a project on the application of IEC 60364-4-44 to Korean electrical installations of buildings sponsored by Korean ministry of commerce, industry and energy for three years(2004.4.1$\sim$2007.3.31). The test field is established in K.E.R.I.(Korea Electrotechnology Research Institute), which is the purpose of evaluating the formula to calculate touch voltage and stress voltage in the IEC standards. This paper presents some considerations and final configuration of test field to evaluate and introduce the IEC 60364-4-44 applicable to domestic rule for the protection against ground fault.

• 대한본초학회지
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• 제31권6호
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• pp.1-9
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• 2016

Objectives : Gamisoyosan (GMS) is a useful prescription for treating insomnia, dysmenorrhea and infertility induced by a stress. Also, GMS has been used traditionally to improve systemic circulation and biological energy production. The purpose of this study was to assess the anti-oxidant activity and anti-inflammatory effects of Gamisoyosan Formulation (Soft extract, GMS-SE). Methods : The biological activities such as anti-oxidant and anti-inflammatory effects were measured through cell line-based in vitro assay. We investigated the anti-oxidant properties of GMS-SE on the 1,1-diphenyl-2-picryhydrazyl (DPPH) radical, contents of total flavonoid and polyphenol. GMS-SE compared to butyl hydroxy anizole (BHA). Furthermore, based on this result the anti-inflammatory effects of GMS-SE have verified by mechanism from LPS- treated Raw264.7 macrophages. Results : The anti-oxidant activities of GMS-SE increased markedly, in a dose-dependent manner. The GMS-SE showed significant scavenging activity (GMS-SE $500{\mu}g/m{\ell}$ : $32.77{\pm}1.65%$, GMS-SE $1000{\mu}g/m{\ell}$ : $45.06{\pm}1.04%$ and BHA $100{\mu}g/m{\ell}$ : $39.25{\pm}2.41%$ for DPPH assay). and, The total phenolic compound and flavonoids contents of GMS-SE were $73.93{\pm}6.87{\mu}g/mg$ and $698.75{\pm}6.78{\mu}g/mg$. GMS-SE which is LPS has diminished in the LPS-induced release of inflammatory mediators (NO, iNOS, COX2 and PGE2) and pro-inflammatory cytokines (TNF-${\alpha}$, IL-6 and IL-$1{\beta}$) from the RAW264.7 macrophages. Moreover, GMS-SE inhibited the activation of phosphorylation of p38 and ERK MAPKs by induced LPS. Conclusion : The present results indicate that GMS-SE has an anti-oxidant and anti-inflammatory properties, therefore may be beneficial in diseases which related to oxidative stress-mediated inflammatory disorders.

• 대한본초학회지
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• 제33권2호
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• pp.69-77
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• 2018

Objectives : Daesiho-tang (DSHT) has been widely used in the treatment of cerebral infarct in traditional medicine. However, there was not report on the anti-obesity-related diseases efficacy of DSHT. In this study, we investigated the effects for the new formulation of DSHT, on the adipocyte differentiation cycle in 3T3-L1 cells. Methods : 3T3-L1 cells were treated with DSHT (50, 100, $200{\mu}g/m{\ell}$) during differentiation for 6 days. Also, the inhibitory effect of DSHT against 3T3-L1 adipogenesis was evaluated in various stage of adipogenesis such as early (0-2day), intermediate (2-4day), and terminal stage (4-6day). The accumulation of lipid droplets was determined by Oil Red O staining. and, the expressions of genes related to adipogenesis were measured by RT-PCR and Western blot analyses. Results : DSHT showed inhibitory activity on adipocyte differentiation at 3T3-L1 preadipocytes without affect cell toxicity as assessed by measuring fat accumulation and adipogenesis. In addition, DSHT significantly reduced the expression levels of several adipocyte marker genes including proliferator activated $receptor-{\gamma}$ ($PPAR-{\gamma}$) and CCAAT/ enhancer-binding $protein-{\alpha}$ ($C/EBP-{\alpha}$). Also, the anti-adipogenic effect of DSHT was strongly limited in the intermediate (2-4 day), terminal stage (4-6 day) of 3T3-L1 adipogenesis. In addition, the DSHT treatment down- regulated mRNA expression levels of $PPAR-{\gamma}$,, $C/EBP-{\alpha}$ in mature 3T3-L1 adipocytes. Conclusions : These results suggest that, the ability of DSHT has inhibited overall adipogenesis and lipid accumulation in the 3T3-L1 cells. The new formulation of DSHT may be a promising medicine for the treatment of obesity and related metabolic disorders.

• Journal of Radiation Protection and Research
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• 제47권4호
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• pp.204-213
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• 2022

Background: The accident at the Fukushima Daiichi nuclear power plant increased the level of anxiety related to the radioactive contamination of various foods sourced in Japan. Particularly, after the accident, the detection of artificial radionuclides in locally produced foods raised food safety concerns. In this study, the radioactivity concentrations and annual ingestions of ⁴⁰K and ¹³⁷Cs in food products commonly and frequently consumed by the general public were investigated, and the annual effective dose of each was evaluated. Materials and Methods: The 2016-2018 data from the Radiation Safety Management Report released by the Korea Nuclear Safety Technology Center was referenced for the evaluation of the amounts of ⁴⁰K and ¹³⁷Cs contained in food. Using the food-ingestion survey mentioned above as a reference, we selected 62 foods to include in our radioactivity concentration and dose assessment. We also developed a questionnaire and evaluated the responses from the subjects who answered the questionnaire. Results and Discussion: The radioactivity concentration of ¹³⁷Cs was found to be close to or below the level of minimum detectable activity. Additionally, the annual ingestion of 62 foods was 294.77 kg/yr, the effective doses from ⁴⁰K and ¹³⁷Cs were 136.4 and 0.163 μSv/yr, respectively. Conclusion: Thus, the findings confirmed that the effective dose from ⁴⁰K and ¹³⁷Cs in food tends to be lower than the effective dose limit of 1 mSv/yr suggested by the International Commission on Radiological Protection (ICRP) Publication 60. The questionnaire developed in this study is expected to be useful for estimating the annual effective dose status of Korean adults who consume foods containing ⁴⁰K and ¹³⁷Cs.

• 대한본초학회지
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• 제29권6호
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• pp.117-123
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• 2014

Objectives : Sinhyowoldo-san (SHWDS) is said to be a traditional medicine used for shigellosis, abdominal pain, diarrhea. But mechanism of SHWDS mediated-modulation of immune function is not sufficiently understood. To ascertain the molecular mechanisms of SHWDS 70% EtOH extract on pharmacological and biochemical actions in inflammation, we researched the effect of pro-inflammatory mediators in phorbol-12-myristate-13-acetate (PMA)+ A23187-activated human mast cell line (HMC-1). Methods : In the present research, cell viability was measured by MTS assay. pro-inflammatory cytokine production was measured by performing enzyme-linked immunosorbent assay (ELISA), reverse transcription polymerase chain reaction (RT-PCR), and western blot analysis to analyze the activation of mitogen-activated protein kinases (MAPKs), nuclear factor kappa-light-chain-enhancer of activated B cells ($NF-{\kappa}B$). The investigation focused on whether SHWDS inhibited the expressions of interleukin-6 (IL-6), interleukin-8 (IL-8), MAPKs and $NF-{\kappa}B$ in PMA+A23187-activated HMC-1 cells. Results : SHWDS has no cytotoxicity at measured concentration (50, 100, and $250{\mu}g/ml$). SHWDS ($250{\mu}g/ml$) inhibits pro-inflammatory cytokine expression in PMA+ A23187-activated HMC-1 cells. Moreover, SHWDS inhibited cyclooxygenase (COX)-2 expression. In activated HMC-1 cells, SHWDS suppressed phosphorylation of extracellular signal-regulated kinase (ERK 1/2) and c-jun N-terminal Kinase (JNK 1/2). Then, SHWDS suppressed activation of nuclear factor $NF-{\kappa}B$ in nuclear, degradation of IkB ${\alpha}$ in cytoplasm. Conclusions : We propose that SHWDS has an anti-inflammatory therapeutic potential, which may result from inhibition of ERK 1/2, JNK 1/2 phosphorylation and $NF-{\kappa}B$ activation, thereby decreasing the expression of pro-inflammatory genes.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제27권1호
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• pp.2-30
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• 2016

This article provides an overview of the developmental history and rationale of medical ethics to establish the code of ethics and professional conduct of the Korean Academy of Child and Adolescent Psychiatry (KACAP). Most medical professional organizations have their own codes of ethics and conduct because they have continuous responsibility to regulate professional activities and conducts for their members. The Ethics and Award Committee of the KACAP appointed a Task-Force to establish the code of ethics and conduct in 2012. Because bioethics has become global, the Ethics Task Force examined global standards. Global standards in medical ethics and professional conduct adopted by the World Medical Association and the World Psychiatric Association have provided the basic framework for our KACAP's code of ethics and professional conduct. The Code of Ethics of the Americal Academy of Child and Adolescent Psychiatry has provided us additional specific clarifications required for child and adolescent patients. The code of ethics and professional conduct of the KACAP will be helpful to us in ethical clinical practice and will ensure our competence in recognizing ethical violations.

• 한국콘텐츠학회논문지
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• 제20권11호
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• pp.170-183
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• 2020

본 연구는 항공승무원의 감정노동으로 인한 조직몰입의 문제와 조직몰입이 저하되어 나타나는 서비스 품질 문제를 해결하는 방안을 모색하기 위해 감정노동과 조직몰입의 영향관계를 알아보고자 하였다. 또한 항공서비스품질 저하에 따른 보완 요인으로 사회적 지지가 미치는 영향에 대하여 순차적인 관계루트를 찾아보고자 한다. 본 연구는 2020년 1월부터 약 1개월 동안 설문조사를 실시하였고, 총 426부가 최종분석에 사용되었다. 자료분석은 SPSS 23.0과 AMOS 23.0 통계프로그램을 사용하였다. 본 연구의 결과는 다음과 같다. 첫째, 항공 승무원의 감정노동은 사회적 지지인 동료지지, 가족지지, 팀장지지에 모두 부적인 영향을 미치는 것으로 나타났다. 둘째, 항공승무원의 사회적지지 중, 동료지지와 팀장지지가 조직몰입에 정적인 영향을 미치는 것으로 나타났다. 셋째, 항공승무원의 감정노동은 조직몰입에 부적인 영향을 미치는 것으로 나타났다. 넷째, 항공승무원의 감정노동과 조직몰입의 관계에서 사회적 지지 중, 동료지지와 팀장지지가 유의한 매개역할을 하고 있음을 검증하였다.

• 한국콘텐츠학회논문지
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• 제7권10호
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• pp.262-273
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• 2007

본 연구의 목적은 여성 스포츠팬을 스포츠 마케팅의 세그먼트로 인정하고 마케팅을 펼치기 위한 초기과제로, 여성 스포츠팬의 스포츠 관람동기요인을 규명하고 동기요인 중 동일시수준에 따라 재관람의도와 구전의도에 영향을 주는 요인을 밝히는 것에 있다. 이러한 목적을 달성하기 위해 여성 스포츠팬을 대상으로 포커스그룹인터뷰를 실시한 후, 경기장을 찾은 여성관람객을 대상으로 표집이 이루어졌으며, 총 248명의 설문지를 분석에 사용하였다. 자료처리는 기술통계분석, 상관분석, 신뢰도분석, 확인적 요인분석, 회귀분석 등을 이용하였으며 본 연구에서 도출된 결과는 다음과 같다. 첫째, 여성 스포츠팬의 관람동기요인은 9개의 요인으로 나타났으며, 그 중 기술, 성취감, 드라마, 그리고 일상탈출요인이 여성 스포츠팬의 재관람의도에 긍정적인 영향을 미친다. 둘째, 여성 스포츠팬의 관람동기 요인 중 구전의도에 긍정적 영향을 미치는 요인은 선수기술, 성취감, 그리고 사회성요인이다. 셋째, 여성스포츠 팬의 관람동기요인 중 재관람의도에 영향을 미치는 요인은 동일시수준에 따라 차이가 있었다. 넷째, 여성 스포츠 팬의 관람동기요인 중 구전의도에 영향을 미치는 요인은 동일시수준에 따라 차이가 있었다.