• Journal of Korean Society for Quality Management
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• v.42 no.4
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• pp.717-728
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• 2014

Purpose: The purpose of this research is to develop a model tat explains the motivation of mobile coupon gift intention in mobile instant messenger service. Methods: This study utilized Structural Equation Model to clarify factors those influence mobile coupon gift intention under mobile messenger environment. Results: The research model in this study is verified with two hundreds sample data. This study found that mobile coupon gift-givers's giving intention is influenced by experimental and obligated motivation, price utility, social value of gift-giving, and perceived ease of use of the technology. Conclusion: This study verified five factors those influence to mobile coupon gift-giving intention. Although this study initially suggests and verify gift-giving intention model, we expect further research that related to other factors affecting the intention and other recent technology factors such as personal innovation and others.

• BMB Reports
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• v.35 no.6
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• pp.583-589
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• 2002

The signal transducer and activator of transcription (STAT)1 is a cytoplasmic-transcription factor that is phosphorylated by Janus kinases (Jak) in response to interferon $\gamma$ (IFN-$\gamma$). The phosphorylated STAT1 translocates to the nucleus, where it turns on specific sets of IFN-$\gamma$-inducible genes, such as the interferon regulatory factor (IRF)-1. We show here that gamma irradiation reduces the IFN-$\gamma$ mRNA expression. The inhibition of the STAT1 phosphorylation and the IRF-1 expression by gamma irradiation was also observed. In contrast, the mRNA levels of IL-5 and transcription factor GATA-3 were slightly induced by gamma irradiation when compared to the non-irradiated sample. Furthermore, we detected the inhibition of cell-mediated immunity by gamma irradiation in the allogenic-mixed lymphocytes' reaction (MLR). These results postulate that gamma irradiation induces the polarized-Th2 response and interferes with STAT1 signals, thereby causing the immunosuppression of the Th1 response.

• Molecular & Cellular Toxicology
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• v.2 no.4
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• pp.229-235
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• 2006

Volatile organic compounds (VOCs) are a major component of urban air pollution. It is documented that low exposure levels of VOCs induce alterations in immune reactivity resulting in a subsequent higher risk for the development of allergic reactivity and asthma. Despite these facts, there are few reports on the affected primary target and the underlying effective causal mechanisms. So in this study, to better understand the risk of BTX (benzene, toluene and o-xylene) which are the major VOCs and to identify novel biomarkers on immune response to these VOCs exposure in human T lymphocytes, we performed the toxicogenomic study by analyzing of gene expression profiles using 35 k human oligo-microarray. BTX generated specific gene expression patterns in Jurkat cell line. By clustering analysis, we identified some genes as potential markers on immuno-modulating effects of BTX. Four genes of these, HLA-DOA, ITGB2, HMGA2 and 5TAT4 were the most significantly affected by BTX exposure. Thus, this study suggests that these differentially expressed immune genes may play an important role in the pathogenesis on BTX exposure and have significant potential as novel biomarkers of exposure, susceptibility and response to BTC.

• The Korean Journal of Food And Nutrition
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• v.20 no.4
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• pp.356-362
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• 2007

This study was carried to develop the new material of functional food which antioxidant of natural substances of sprouts. We compared antioxdiative activity and antioxidant substances exist in sprouts. Antioxidaive activities of sprouts were measured by total polyphenolic acid contents, electron donating activity(EDA), SOD-liked activity and hydroxyl radical scavenging ability. Total polyphenolic acid content was very higher in Rape sprouts extract(Rap) than other sprout extracts. Also Rape extract was showed the most excellent antioxdiative activity in SOD liked activity at 86.94%. The EDA was ordered Rape sprouts extract(Rap)>Tatsoi sprouts extract(Tat)>Broccoli sprouts extract(Bro)>Alfalfa sprout extract(Alf). Hydroxy radical scavenging ability was the most effective in Rape sprouts extract(Rap). Therefore we could be certain that Rape sprouts extract(Rap) was the most effective in antioxidative activity from sprouts.

• YAKHAK HOEJI
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• v.15 no.3_4
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• pp.87-92
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• 1971

Fourteen novel N,N'-disubstitued thiourea derivatives were synthesized by Hugershof reaction. Antitubercular activities of ten compounds against Mycobacterium tuberculosis H$_{37}$ Rv were tested and was found tat 1-cyclohexyl-3-(4-benzenesulfonepiperidide)-2-thiourea was considerably active at 1mg/ml and 1-$\alpha$-naphthyl-3-(4-benzenesulfonepiperidide)-2-thiourea was slightly active at 1mg/ml. Antibacterial activity of the newly synthesized compounds against E. coli, Sta. aureus and Streptococcus hemolyticus were also tested. 1-cyclohexyl-3-(4-benzenesulfonepiperidide)-2-thiourea was makedly active against E. coli, Sta, aureus and Streptococcus hemolyticus; Phenol coefficients against E. coli, Sta, aureus and Streptococcus hemolyticus were 30,17.5 and 21.3, respectively. 1,1'-p-phenylene-3,3'bis[N-(2-thiazolyl)-sulfamylphenyl]-2,2'-dithiourea and 1-$\alpha$-naphthyl-3-(4-benzenesulfonepiperidide)-2-thiourea were considerably active against E. coli: phenol coefficients, 18.8 and 37.5 respectively. 1-(4-ethoxyphenyl)3-(4-sulfamylphenyl)-2-thiourea was active against Streptococcus hemolyticus: phenol coefficients, 22.5. 1-$\alpha$-naphthyl-3-(4-sulfamylphenyl)-2-thiourea, 1-$\betha$-naphthyl-3-[4-N-(2-thiazolyl)-sulfamylphenyl]-2-thiourea and 1-$\alpha$-naphthyl-3-(4-benzenesulfonepiperidide)-2-thiourea were active against Sta. aureus: phenol coefficients, 17.5, 20.0 and 18.8 respectively.

• The Korean Society of Law and Medicine
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• v.14 no.2
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• pp.87-112
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• 2013

Vor kurzer Zeit gibt es viele Diskussion $\ddot{u}$ber die Unterbrechung der Freiheitsstrafe aufgrund der Krankheit. Man wollte ihre Voraussetzungen einerseits durch 'Kommission f$\ddot{u}$r die Unterbrechung der Freiheitsstrafe' andererseits durch doppelte medizinische Gutachten strenger machen. Jedoch muss man auf die im voraus zu entscheidende Frage antworten, ob das Recht des Gefangenen auf Gesundheit geschutzt wird, insbesondere die Gefangenen in Justizvollzugsanstalten medizinische Behandlungen genug nutzen k$\ddot{o}$nnen. Meine Antwort ist 'Nein!'. Im kStvollzG bestehen die Regelungen f$\ddot{u}$r medizinische Behandlung mit staatlicher Beteilung und mit Selbstbeteiligung au${\ss}$er Justizvollzugsanstalten. Im Prinzip muss der Staat f$\ddot{u}$r die Behandlungskosten der Gefangenen bezahlen. In der Tat aber nicht. In diesem Beitrag wurden die Antwort auf die Vorfrage aufgrund der Erfolgen der zwei Rundfragen zu geben versucht, um die Voraussetzungen der Unterbrechung der Freiheitsstrafe strenger zu machen.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.25 no.2
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• pp.182-191
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• 2001

The paper describes the improvement on concurrent subspace optimization(CSSO) via automatic differentiation. CSSO is an efficient strategy to coupled multidisciplinary design optimization(MDO), wherein the original design problem is non-hierarchically decomposed into a set of smaller, more tractable subspaces. Key elements in CSSO are consisted of global sensitivity equation, subspace optimization, optimum sensitivity analysis, and coordination optimization problem that require frequent use of 1st order derivatives to obtain design sensitivity information. The current version of CSSO adopts automatic differentiation scheme to provide a robust sensitivity solution. Automatic differentiation has numerical effectiveness over finite difference schemes tat require the perturbed finite step size in design variable. ADIFOR(Automatic Differentiation In FORtran) is employed to evaluate sensitivities in the present work. The use of exact function derivatives facilitates to enhance the numerical accuracy during the iterative design process. The paper discusses how much the automatic differentiation based approach contributes design performance, compared with traditional all-in-one(non-decomposed) and finite difference based approaches.

• Journal of the Mineralogical Society of Korea
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• v.17 no.2
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• pp.169-176
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• 2004

The Osaeg hotspring (long. $128^{\circ}$ 56'E, tat. $37^{\circ}$ 06'N) located in the northester part of Kangwon-do, Korea. The pH value of the hot spring water is 8.31, and the EC, $SO_4$, F and Na are 196 ${\mu}\textrm{s}$/cm, 10.88 mg/L, 8.19 mg/L, and 37.07 mg/L, respectively. The ocherous precipitates are precipitated on the stream bottom of Osaeg hot spring drainage. X-ray diffraction analysis (XRD), scanning electron microscopy (SEM) and stereo-microscope were used to analyze the precipitates. X-ray diffraction analysis shows that the precipitates consist mainly of poorly crystalline materials and messelite. Many spherical and rod-shaped bacteria-like forms were observed in the precipitates.

• Proceedings of the Korean Geotechical Society Conference
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• 1992.10a
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• pp.55-60
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• 1992

Hydraulically filled ground is formed by the settling of soil grains from the mixture of soil grains and water. It was generally known that the settling speed of the soil grains in governed by Stokes low. In the case of clayed dredged material, the shape of soil grains is not round, the surface of the soil grains is relatively large compared to the weight of soil grains and inter-grain ionic force is relatively large compared to the wight of soil grains. By this reason the settling and consolidation behavior of hydraulically filled quite different from that of Stokes law. This study investigated the settling and consolidation behavior of hydraulically filled materials of Yeochon industrial complex by large scale laboratory settling & consolidation container. The test results showed tat actual settling speed of soil grains in quite large compared to that of Stokes law. It was turned out that this phenomenon was due to the aggregation of soil grains. Also, it was truned out that the void ration and water content after the completion of settling process was 8.7 and 322% respectively. The consolidtion settlement of clayey hydraulic fill material was predicated better by "incremental small strain" consolidation concept than classical Terzaghj's consolidation concept (infinitesimal strain).

• Journal of the Korean Society for Precision Engineering
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• v.16 no.6
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• pp.36-44
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• 1999

The rapid Tooling technique is classified into two methods: one to directly utilize the model which was made by rapid prototyping technologies for dies, and the other to make a transferred type using the model as a master model and create dies and molds using it. In this study, the Al powder filled resin was made several mixed ratios and meshes sizes, and applied to slurry casting. And, variation of mechanical characteristics such as the shrinkage rate, the tensile strength, the elongation, the hardness, and surface roughness, are measured to compare. Consequently, as higher is the powder mixed ration and as smaller is the grain size of the power, the mechanical characteristics of the final mold are improved. Finally, the metal short fiber which can be fabricated easily and cheaply, if the self-excited vibration of an elastic tool, was also applied to slurry casting. It has been found tat the hardness gets higher, while the shrinkage rate lower, if mixed with short fiber.