• Journal of the Korean Institute of Electrical and Electronic Material Engineers
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• v.24 no.7
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• pp.584-588
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• 2011

The ZnO thin films doped with Ga and Ge (GZO:Ge) were prepared on glass substrate using RF sputtering system. Structural, morphological and optical properties of the films deposited in different temperatures were studied. Proportion of the element of using target was 97 wt% ZnO, 2.5 wt% Ga and 0.5 wt% Ge with 99.99% highly purity. Structural properties of the samples deposited in different temperatures with 200 w RF power were investigated by field emission scanning electron microscopy, FE-SEM images and x-ray diffraction XRD analysis. Atomic force microscopy, AFM images were able to show the grain scales and surface roughness of each film rather clearly than SEM images. it was showed that increasing temperature have better surface smoothness by FE-SEM and AFM images. Transmittance study using UV-Vis spectrometer showed that all the samples have highly transparent in visible region (300~800 nm). In addition, it can be able to calculate bandgap energy from absorbance data obtained with transmittance. The hall resistivity, mobility, and optical band gap energy are influenced by the temperature.

• Biomedical Science Letters
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• v.8 no.3
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• pp.107-113
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• 2002

Enterohemorrhagic Escherichia coli (EHEC) strains of serotype O157:H7 have been shown to colonize the intestinal epithelial cell by the attaching and effacing (AE) mechanism. The AE lesion is mediated by an intimin, of which production and expression are controlled by a 3-Kb eaeA gene located EHEC chromosomal DNA. If the eaeA gene is mutated, EHEC O157:H7 strains lose capacity of adhesion to intestinal epithelial cells. In this study, a 891 bp of the 3'-end region of a gamma intimin was amplified by polymerase chain reaction (PCR). The PCR product was inserted into pSTBlue-1 cloning vector and transformed into DE3 (BL21) competent cell. After plasmid mini-preparation and restriction enzyme digestion of eaeA/891-pSTBlue-1 vector, target eaeA gene was re-inserted into pET-28a expression vector and was transformed. Then the expression of recombinant eaeA/891 (891 bp) gene was induced by isopropyl-$\beta$-D-thiogalactopyranoside (IPTG). The expression of the 40-KDa recombinant protein was identified in SDS-PAGE and confirmed by immunoblotting using the His.Tag$^{\circledR}$ and T$_{7}$.Tag$^{\circledR}$ monoclonal antibody. This recombinant protein expressed by eaeA gene could be applied in further studies on the mechanisms of E. coli O157:H7 infection and the development of recombinant vaccine.

• Journal of Korean Institute of Industrial Engineers
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• v.19 no.2
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• pp.53-64
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• 1993

Successful completion of a visual task in a predetermined time is very crucial to many operations such as piloting an aircraft. Although existing ergonomic interface models often provide a function of vision tests, it determines only the visibility at any given location. To complement this problem in existing models, the isoresponse time region considering the factors related to visual tasks is presented. Using a multiple regression model, equal response time regions were obtained within which mean response time is expected to be the same and is asymmetrical in shape. Among the factors considered, expectancy significantly decreased response time, and when cued, the effects of field heterogeneity, target uncertainty, density, size contrast and peripheral position on search time were less significant than those in unexpected cases. Response time and error rate, gender and visual acuity were not significantly correlated, and response time and age was positively correlated. These results are expected to be directly applicable to designing various visual tasks in real-life situations.

• Journal of The Korean Society of Agricultural Engineers
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• v.49 no.3
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• pp.63-68
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• 2007

The LRA(Logistic Regression Analysis) conducts a quantitative analysis by collecting a lot of samples and the AHP(Analytic Hierarchy Program) makes use of expert decision influenced by subjective judgment to a certain degree. This study is to suggest a combination method in mapping landslide hazard by giving equal weight for the result of LRA and AHP. Topographic factors(slope, aspect, elevation), soil dram, soil depth and land use were adopted to classify landslide hazard areas. The three methods(LRA, AHP, the combined approach) was applied to a $520km^2$ region located in the middle of South Korea which have occurred 39 landslides during 1999 and 2003. The suggested method showed 58.9% matching rate for the real landslide sites comparing with the classified areas of high-risk landslide While LRA and AHP Showed 46.1% and 48.7% matching rates respectively. Further studies are recommended to find the optimal combining weight of LRA and AHP with more landslide data.

• Korean Journal of Cognitive Science
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• v.12 no.4
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• pp.41-47
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• 2001

Palmer and Rock (1994) proposed that a connected region of uniform visual properties (uniform connectedness) strongly tends to be organized as a single perceptual unit To test this hypothesis using briefly presented forms three experiments were executed. In Experiment 1 and 2 participants were asked to report the identity of a post-cued target. and there was no difference between connected and disconnected displays. In Experiment 3 participants were asked to report the predesignated name of each whole display and the accuracy rate was higher in the connected displays than in the disconnected ones. However negative repetition effects were observed consistently in all the experiments. This indicates uniform connectedness does not have a strong effect in perceiving briefly presented forms.

• Journal of Korea Multimedia Society
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• v.23 no.1
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• pp.15-23
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• 2020

Recently, the increase in the elderly population due to an aging society has led to a relative increase in senile diseases such as vascular dementia or Alzheimer's disease, and the social burden for rehabilitation has increased. In addition, studies have been conducted for the risk assessment and prevention of musculoskeletal disorders. The purpose of this study is to suggest a system that can be used to help with dementia prevention training by tracking the movement of motion and virtual reality contents for the risk factors of musculoskeletal disorders of the elderly. We propose a training method for preventing dementia through musculoskeletal motion analysis algorithm and virtual reality content. Through motion recognition algorithm based on motion region design, we will track and analyze the moving radius of the target joint. The purpose of this study is to calculate and evaluate scores based on the time to accomplish the goals on virtual reality contents for the prevention of musculoskeletal disorders and the support of dementia prevention training, and the degree of difficulty, and to analyze the correlation between the results of performing K-MMSE and VR contents.

• Asian Journal of Atmospheric Environment
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• v.9 no.4
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• pp.272-279
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• 2015

The information about the dispersion and scavenging of traffic-related pollutants at the locations near busy expressways is very helpful to highway planners for developing better plans to reduce exposures to air pollution for people living as well as children attending schools and child care centers near roadways. The objective of the current study was to give information in the dispersion and scavenging of vehicle-derived pollutants at the region near a busy urban expressway by a combination of two different model calculations. The modified Gaussian dispersion model and the Lagrange type below-cloud scavenging model were applied to evaluate $NO_x$ dispersion and DEP (Diesel exhaust particles) wet removal, respectively. The highest $NO_x$ was marked 53.17 ppb within 20-30 meters from the target urban expressway during the heaviest traffic hours (08:00AM-09:00AM) and it was 2.8 times higher than that of really measured at a nearby ambient measuring station. The calculated DEP concentration in size-resolved raindrops showed a continuous decreasing with increasing raindrop size. Especially, a noticeable decrease was found between 0.2 mm and 1.0 mm raindrop diameter.

• The Korean Journal of Physiology and Pharmacology
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• v.20 no.2
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• pp.161-168
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• 2016

Abnormal localization of tumor suppressor proteins is a common feature of renal cancer. Nuclear export of these tumor suppressor proteins is mediated by chromosome region maintenance-1 (CRM1). Here, we investigated the antitumor effects of a novel reversible inhibitor of CRM1 on renal cancer cells. We found that S109 inhibits the CRM1-mediated nuclear export of RanBP1 and reduces protein levels of CRM1. Furthermore, the inhibitory effects of S109 on CRM1 is reversible. Our data demonstrated that S109 significantly inhibits proliferation and colony formation of renal cancer cells. Cell cycle assay showed that S109 induced G1-phase arrest, followed by the reduction of Cyclin D1 and increased expression of p53 and p21. We also found that S109 induces nuclear accumulation of tumor suppressor proteins, Foxo1 and p27. Most importantly, mutation of CRM1 at Cys528 position abolished the effects of S109. Taken together, our results indicate that CRM1 is a therapeutic target in renal cancer and the novel reversible CRM1 inhibitor S109 can act as a promising candidate for renal cancer therapy.

• Journal of the Korean Magnetic Resonance Society
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• v.20 no.4
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• pp.129-137
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• 2016

Transmembrane(TM) proteins are closely related to transport, channel formation, signaling, cell to cell interaction, so they are the crucial target of modern medicinal drugs. In order to study the structure and function of these TM proteins, it is important to prepare reasonable amounts of proteins. However, their preparation is seriously difficult and time-consuming due to insufficient yields and low solubility of TM proteins. We tried to produce large amounts of Syndecan-4 containing TM domain(SDC4-TM) that is related to the wound healing and tumor. Also, mutated SDC4-TM was studied to investigate structural change by modification of dimerization motif. We performed the structure determination by the Polarity Index at Slanted Angle (PISA) wheel pattern analysis based on $^{15}N-^1H$ 2D SAMPI-4 solid-state NMR of SDC4-TM and computational modeling using Discovery Studio 2016.

• Journal of Korea Multimedia Society
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• v.14 no.12
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• pp.1613-1620
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• 2011

Roof structure of the traditional buildings in the Northeast Asia region including Korea contains the most complicated and crucial components of the building and therefore the issues such as cost down, productivity and the attempt to combine the traditional building methodology with contemporary building technology turn out to be vital to the survival of the old yet disconnected traditional building industry. One of the distinctive modern building technologies is handling life-cycle building information by constructing virtual buildings using BIM, building information modeling tools. In this paper we follow a procedure to implement some of the design modules to be applied in BIM tools which are platforms for constructing virtual building models. We focus on Gong-po components namely the bracket-sets which are the essential part that connects the middle parts to the top parts (the roof structure) which are considered to be the most elaborate parts of the traditional buildings. The target building to work with in this paper is the Sung-Rye-Moon which has special cultural and social meanings nowadays and we tested our understanding and the design modules such as the bracket-sets by constructing a virtual building model of Sung-Rye-Moon.