• Korean Security Journal
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• no.45
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• pp.243-271
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• 2015

The primary aim of this study is to provide effective operational directions of multi-purpose maneuver patrol via practical analysis on the fear of crime and its impact factors in the Hot Spots Policing target region. Comparative Analysis on fear of crime and its impact factors such as informal social control, disorder, and the perception of police activities is conducted in regions of maneuver patrol against its neighborhood. In Conclusion, no evident differences in fear of crime between the regions of maneuver patrol and its neighborhood were found. However, regions of maneuver patrol displayed significant distinctions in informal social control and perception of crime frequency in comparison to its neighborhood of no such patrol. In addition, it was noticed that in both regions disorder and perception of crime frequency served as the impact factors of fear of crime, which in part exhibits positive relationship with perception of hot spots policing. This study concludes that criterion in deciding on the regions of maneuver patrol should include subjective impact factors such as fear of crime. Furthermore, it suggests that along with the current unsatisfactory maneuver patrol system there needs specific guideline to enhance the perception of police activities including strengthened interactions with residents, improvement in social disorder.

• Molecules and Cells
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• v.45 no.7
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• pp.465-478
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• 2022

MicroRNAs (miRNAs) are a class of small non-coding RNAs that regulate the expression of target messenger RNA (mRNA) complementary to the 3' untranslated region (UTR) at the post-transcriptional level. Hsa-miR-422a, which is commonly known as miRNA derived from transposable element (MDTE), was derived from short interspersed nuclear element (SINE). Through expression analysis, hsa-miR-422a was found to be highly expressed in both the small intestine and liver of crab-eating monkey. AT-Rich Interaction Domain 5 B (ARID5B) was selected as the target gene of hsa-miR-422a, which has two binding sites in both the exon and 3'UTR of ARID5B. To identify the interaction between hsa-miR-422a and ARID5B, a dual luciferase assay was conducted in HepG2 cell line. The luciferase activity of cells treated with the hsa-miR-422a mimic was upregulated and inversely downregulated when both the hsa-miR-422a mimic and inhibitor were administered. Nuclear factor erythroid-2 (NF-E2) was selected as the core transcription factor (TF) via feed forward loop analysis. The luciferase expression was downregulated when both the hsa-miR-422a mimic and siRNA of NF-E2 were treated, compared to the treatment of the hsa-miR-422a mimic alone. The present study suggests that hsa-miR-422a derived from SINE could bind to the exon region as well as the 3'UTR of ARID5B. Additionally, hsa-miR-422a was found to share binding sites in ARID5B with several TFs, including NF-E2. The hsa-miR-422a might thus interact with TF to regulate the expression of ARID5B, as demonstrated experimentally. Altogether, hsa-miR-422a acts as a super enhancer miRNA of ARID5B by collaborating with TF and NF-E2.

• Animal Bioscience
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• v.36 no.10
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• pp.1488-1498
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• 2023

Objective: α_S1-Casein is more closely associated with milk allergic reaction than other milk protein components. microRNA (miRNA) is a class of small non-coding RNAs that modulate multiple biological progresses by the target gene. However, the post-transcriptional regulation of α_S1-casein expression by miRNA in ruminants remains unclear. This study aims to explore the regulatory roles of miR-380-3p on α_S1-casein synthesis in goat mammary epithelial cells (GMEC). Methods: α_S1-Casein gene and miR-380-3p expression was measured in dairy goat mammary gland by quantitative real-time polymerase chain reaction (qRT-PCR). miR-380-3p overexpression and knockdown were performed by miR-380-3p mimic or inhibitor in GMEC. The effect of miR-380-3p on α_S1-casein synthesis was detected by qRT-PCR, western blot, luciferase and chromatin immunoprecipitation assays in GMEC. Results: Compared with middle-lactation period, α_S1-casein gene expression is increased, while miR-380-3p expression is decreased during peak-lactation of dairy goats. miR-380-3p reduces α_S1-casein abundance by targeting the 3'-untranslated region (3'UTR) of α_S1-casein mRNA in GMEC. miR-380-3p enhances β-casein expression and signal transducer and activator of transcription 5a (STAT5a) activity. Moreover, miR-380-3p promotes β-casein abundance through target gene α_S1-casein, and activates β-casein transcription by enhancing the binding of STAT5 to β-casein gene promoter region. Conclusion: miR-380-3p decreases α_S1-casein expression and increases β-casein expression by targeting α_S1-casein in GMEC, which supplies a novel strategy for reducing milk allergic potential and building up milk quality in ruminants.

• Korean Journal of Radiology
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• v.21 no.4
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• pp.431-441
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• 2020

Objective: To compare the diagnostic performance and interobserver variability of strain ratio obtained from one or two regions of interest (ROI) on breast elastography. Materials and Methods: From April to May 2016, 140 breast masses in 140 patients who underwent conventional ultrasonography (US) with strain elastography followed by US-guided biopsy were evaluated. Three experienced breast radiologists reviewed recorded US and elastography images, measured strain ratios, and categorized them according to the American College of Radiology breast imaging reporting and data system lexicon. Strain ratio was obtained using the 1-ROI method (one ROI drawn on the target mass), and the 2-ROI method (one ROI in the target mass and another in reference fat tissue). The diagnostic performance of the three radiologists among datasets and optimal cut-off values for strain ratios were evaluated. Interobserver variability of strain ratio for each ROI method was assessed using intraclass correlation coefficient values, Bland-Altman plots, and coefficients of variation. Results: Compared to US alone, US combined with the strain ratio measured using either ROI method significantly improved specificity, positive predictive value, accuracy, and area under the receiver operating characteristic curve (AUC) (all p values < 0.05). Strain ratio obtained using the 1-ROI method showed higher interobserver agreement between the three radiologists without a significant difference in AUC for differentiating breast cancer when the optimal strain ratio cut-off value was used, compared with the 2-ROI method (AUC: 0.788 vs. 0.783, 0.693 vs. 0.715, and 0.691 vs. 0.686, respectively, all p values > 0.05). Conclusion: Strain ratios obtained using the 1-ROI method showed higher interobserver agreement without a significant difference in AUC, compared to those obtained using the 2-ROI method. Considering that the 1-ROI method can reduce performers' efforts, it could have an important role in improving the diagnostic performance of breast US by enabling consistent management of breast lesions.

• Journal of the Institute of Electronics Engineers of Korea SP
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• v.46 no.3
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• pp.112-118
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• 2009

Skin color segmentation techniques have been widely utilized for face/hand detection and tracking in many applications such as a diagnosis system using facial information, human-robot interaction, an image retrieval system. In case of a video image, it is common that the skin color model for a target is updated every frame for the robust target tracking against illumination change. As for a single image, however, most of studies employ a fixed skin color model which may result in low detection rate or high false positive errors. In this paper, we propose a novel method for effective skin color segmentation in a single image, which modifies the conditions for skin color segmentation iteratively by the image feedback of segmented skin color region in a given image.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.10 no.6
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• pp.55-62
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• 2010

Monitoring systems are able to report certain events at region of interest(ROI) and to take an appropriate action. From industrial product line full of robots to fire detection, intrusion detection, smart grid application, environmental pollution alarm system, monitoring system has widely used in diverse industry sector. Recently, due to advance of wireless communication technology and availability of low cost sensors, intelligent and/or smart monitoring systems such as sensor networks has been developed. Several deployment methods are introduced to meet various monitoring needs and deployment performance criteria are also summarized to be used to identify weak point and be useful at designing monitoring systems. Both efficiency during deployment and usefulness after the deployment should be assessed. Efficiency factors during deployment are elapsed time, energy required, deployment cost, safety, sensor node failure rate, scalability. Usefulness factors after deployment are ROI coverage, connectivity, uniformity, target density similarity, energy consumption rate per unit time and so on.

• 한국신재생에너지학회:학술대회논문집
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• 2010.11a
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• pp.55.1-55.1
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• 2010

Cost efficient and large area deposition of superior quality $Al_2O_3$ doped zinc oxide (AZO) films is instrumental in many of its applications including solar cell fabrication due to its numerous advantages over ITO films. In this study, AZO films were prepared by a highly efficient rotating cylindrical dc magnetron sputtering system using AZO target, which has a target material utilization above 80%, on glass substrates in argon ambient. A detailed analysis on the electrical, optical and structural characteristics of AZO thin films was carried out for solar cell application. The properties of films were found to critically depend on deposition parameters such as sputtering power, substrate temperature, working pressure, and thickness of the films. A low resistivity of ${\sim}5.5{\times}10-4{\Omega}-cm$ was obtained for films deposited at 2kW, keeping the pressure and substrate temperature constant at 3 mtorr and $230^{\circ}C$ respectively, mainly due to an increase in carrier mobility and large grain size which would reduce the grain boundary scattering. The increase in carrier mobility with power can be attributed to the columnar growth of AZO film with (002) preferred orientation as revealed by XRD analysis. The AZO films showed a high transparency of>87% in the visible wavelength region irrespective of deposition conditions. Our results offers a cost-efficient AZO film deposition method which can fabricate films with significant low resistivity and high transmittance that can find application in thin-film solar cells.

• Journal of the Earthquake Engineering Society of Korea
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• v.18 no.3
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• pp.141-150
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• 2014

A methodology to evaluate the seismic performance of interface piping systems that cross the isolation interface in the seismically isolated nuclear power plant (NPP) was developed. The developed methodology was applied to the safety-related interface piping system to demonstrate the seismic performance of the target piping system. Not only the seismic performance for the design level earthquakes but also the performance for the beyond design level earthquakes were evaluated. Two artificial seismic ground input motions which were matched to the design response spectra and two historical earthquake ground motions were used for the seismic analysis of piping system. The preliminary performance evaluation results show that the excessive relative displacements can occur in the seismically isolated piping system. If the input ground motion contained relatively high energy in the low frequency region, we could find that the stress response of the piping system exceed the allowable stress level even though the intensity of the input ground motion is equal to the design level earthquake. The structural responses and seismic performances of piping system were varied sensitively with respect to the intensities and frequency contents of input ground motions. Therefore, for the application of isolation system to NPPs and the verification of the safety of piping system, the seismic performance of the piping system subjected to the earthquake at the target NPP site should be evaluated firstly.

• Journal of the Institute of Electronics Engineers of Korea SP
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• v.48 no.6
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• pp.105-114
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• 2011

The snake algorithm is widely adopted to track objects by extracting the active contour of the object from background. However, it fails to track the target converging to the background if there exists background whose gradient is greater than that of the pixels on the contour. Also, the contour may shrink when the target moves fast and the snake algorithm misses the boundary of the object in its searching window. To alleviate these problems, we propose an improved algorithm that can track object contour more robustly. Firstly, we propose two external energy functions, the edge energy and the contrast energy. One is designed to give more weight to the gradient on the boundary and the other to reflect the contrast difference between the object and background. Secondly, by computing the motion vector of the contour from the difference of the two consecutive frames, we can move the snake pointers of the previous frame near the region where the object boundary is probable at the current frame. Computer experiments show that the proposed method is more robust to the complicated background than the previously known methods and can track the object with fast movement.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.20 no.6
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• pp.1183-1188
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• 2016

Kinect sensor version 2 is a kind of camera released by Microsoft as a computer vision and a natural user interface for game consoles like Xbox one. It allows acquiring color images, depth images, audio input and skeletal data with a high frame rate. In this paper, using depth image, we present a surveillance system of a certain area within Kinect's field of view. With computer vision library(Emgu CV), if an object is detected in the target area, it is tracked and kinect camera takes RGB image to send it in database server. Therefore, a mobile application on android platform was developed in order to notify the user that Kinect has sensed strange motion in the target region and display the RGB image of the scene. User gets the notification in real-time to react in the best way in the case of valuable things in monitored area or other cases related to a reserved zone.