• 한국신재생에너지학회:학술대회논문집
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• 2009.06a
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• pp.460-462
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• 2009

This study has analyzed the scale, location, resource potential and feasibility of offshore wind farm scientifically and systematically based on the national wind map and GIS (Geographic Information System). For long-term wind power development, this study pursues siting strategy building, selection of target area and deciding development priority as well as the presenting a basis for assessment that are necessary for policy decision making by making theme layers under GIS environment. According to the analysis after organizing technological development by stages, even if only the most suitable sites are developed among the area of offshore wind farm candidates that can be developed under the current technological standard, it has been evaluated as being able to develop about 3 times of the wind power dissemination target until 2012. It is expected that about 5% of territorial water area can be developed in a short-term future while the southern offshore area possessing relatively favorable wind resource than the western offshore has been identified as the most feasible site. While about 23% of territorial water area has been classified as potential area for offshore wind farm development in a long-term future, even Jeju Island and offshore of Ulsan possessing excellent wind resource have been analyzed as feasible sites. The feasibility assessment of offshore wind farm development established by this study is expected to assist national strategy building for accomplishing the wind power dissemination target.

• Korean Journal of Veterinary Pathology
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• v.3 no.1
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• pp.7-14
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• 1999

We investigated the effect of a single intravenous dose of Fumonisin $B_1(FB_1$) of rat kidney on the time sequence. Male Sprague-Dawley rats were intravenouslyin jected with FB$_1$at 1.25 mg/kg and were euthanized at 12 hrs, 1, 2, 4, and 6 days after the injection. In $FB_1$ treated rats, serum BUN and creatinine were elevated from 12 hrs. Microscopically, the initial target site was tubules of inner stripe, with mild degenerative and necrotic changes at 12 hrs, but the tubules recovered on day 4. In outer stripe, there were only a few scattered necrotic cells on day 1. These changes became more obvious over the time passed and most severe on day 4. On day 6, regeneration occurred, manifest as hypertrophic, basophilic tubular cells. The dying cells were proved to necrotic cells instead of apoptotic cells by TUNEL. Ultrastructural changes were cytoplasmic vacuole, dilated endoplasmic reticulum, swollen mitochondria, ballooned microvilli of the tubular cell in the outer stripe. These results showed that the renal tubules of outer medulla were the target to $FB_1$-induced nephrotoxicity in the rat. However, initial target was mner stnpe of medulla.

• Journal of Microbiology and Biotechnology
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• v.30 no.5
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• pp.681-688
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• 2020

Bacterial cell-based biosensors, or whole-cell bioreporters (WCBs), are an alternative tool for the quantification of hazardous materials. Most WCBs share similar working mechanisms. In brief, the recognition of a target by sensing domains induces a biological event, such as changes in protein conformation or gene expression, providing a basis for quantification. WCBs targeting heavy metal(loid)s employ metalloregulators as sensing domains and control the expression of genes in the presence of target metal(loid) ions, but the diversity of targets, specificity, and sensitivity of these WCBs are limited. In this study, we genetically engineered the metal-binding loop (MBL) of ZntR, which controls the znt-operon in Escherichia coli. In the MBL of ZntR, three Cys sites interact with metal ions. Based on the crystal structure of ZntR, MBL sequences were modified by site-directed mutagenesis. As a result, the metal-sensing properties of WCBs differed depending on amino acid sequences and the new selectivity to Cr or Pb was observed. Although there is room for improvement, our results support the use of currently available WCBs as a platform to generate new WCBs to target other environmental pollutants including metal(loid)s.

• Natural Product Sciences
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• v.19 no.1
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• pp.49-53
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• 2013

Paeonia lactiflora Pall (PL) has been used as a traditional herbal medicine in China, Korea, and Japan for more 1,200 years. PL has reported to have antioxidant activity and protective effect of cells from oxidative stress, although the mechanism has not been verified. FOXO3a is a transcription factor that binds to its target gene's consensus FOXO binding site. FOXO3a protein modulates the various biological functions including cell cycle control, apoptosis, DNA repair, and ROS detoxification. Therefore, FOXO3a activity is associated with cancer, aging, diabetes, infertility, neurodegeneration, and immune system dysfunction. Here we found that FOXO3a was activated by PL extract. Transcriptional target genes such as MnSOD, p27, and GADD45 were activated by PL extract. Protein levels of MnSOD and catalase were increased, consequently, ROS level was reduced in HEF cells by PL extract. These findings suggest that PL extract has an antioxidant activity through FOXO activation and thereby activation of FOXO target genes, MnSOD and catalase.

• Journal of The Korean Society of Agricultural Engineers
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• v.52 no.3
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• pp.81-88
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• 2010

The purpose of this study is to analyze the spatial characteristics of Namgang-Dam watershed for a Total Maximum Daily Loads (TMDL). Three TMDL target sites, Gyeonghogang1, 2, Namgang-Dam2, are located within Namgang-Dam watershed. Under the current criterion for TMDLs, 3-year arithmetic mean BOD concentration of the target sites should not exceed the target concentration for 2 consecutive years. Two and three times of violation were observed for Gyenghogang2 and Namgang-Dam2 sites while no violation was found for Gyeonghogang1 site. However, no violation was found since 1999 for all three sites. Correlation between each 12 stations within the watershed were analyzed and cluster analysis was conducted to figure out the spatial characteristics of the watershed. Correlation coefficient between Gyonghogang1 and 2 was high (0.758) while the coefficients between lake station (Namgang-Dam2) and stream stations (Gyonghogang1 and 2) were very low. Dendrogram indicated that all of three Namgang-Dam stations were very close and Gyenghogang1, 2 stations were also close.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2002.11a
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• pp.555-559
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• 2002

Internet users can input URL in Address window of browser or click address of site that is registered to Bookmark and sail the world of internet. But, need input of ID and password and mouse click action of 4-5 times to reach on target page that users want. This environment is very annoying work to users who approach specification page repeatedly every day. So, Homepage (first screen) of URL that want is not, Web Page Access Manager's development that can approach to target page that want by mouse click of short once. That may make web users can approach fast on target page, and minimise effort by web sailing.

• Proceedings of the Korea Water Resources Association Conference
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• 2010.05a
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• pp.1355-1359
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• 2010

The purpose of this study is to analyze the spatial characteristics of Namgang-Dam watershed for a Total Maximum Daily Loads(TMDL). Three TMDL target sites, Gyeonghogang1, 2, Namgang-Dam2, are located within Namgang-Dam watershed. Under the current criterion for TMDLs, 3-year arithmetic mean BOD concentration of the target sites should not exceed the target concentration for 2 consecutive years. Two and three times of violation were observed for Gyenghogang2 and Namgang-Dam2 sites while no violation was found for Gyeonghogang1 site. However, no violation was found since 1999 for all three sites. Correlation between each 12 stations within the watershed were analyzed and cluster analysis was conducted to figure out the spatial characteristics of the watershed. Correlation coefficient between Gyonghogang1 and 2 was high (0.758) while the coefficients between lake station (Namgang-Dam2) and stream stations (Gyonghogang1 and 2) were very low. Dendrogram indicated that all of three Namgang-Dam stations were very close and Gyenghogang1, 2 stations were also close.

• Journal of the Korean Institute of Landscape Architecture
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• v.34 no.1 s.114
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• pp.10-20
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• 2006

This study is to introduce the improvement and management of Ecoduct located in Uiwang's Mt. Obong, Gyeonggi province. The inner planting of Ecoduct is not very related to the flora of mountain areas nearby. The difference in the index of plant crown volume(GVZ), the similarity index(S.I.), and monitored animals is significant between Ecoduct and mountain areas. Putting together all of the results, the initial selection of movement and target species is excessive in number. Target species must be selected again. They will be species that are currently found on the site. The Ecoduct space must be divided into two parts: buffer planting space and wildlife corridor. Reforestation is needed since the GVZ is remarkably lower in Ecoduct than in the nearby mountain areas. Besides the vegetation of Ecoduct is densely planted in guidance planting space to connect the southern Quercus mongolica community and the northern Quercus acutissima community. Proper upkeep after construction should be continuously conducted to maintain the procedure of natural change.

• Earthquakes and Structures
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• v.17 no.3
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• pp.271-282
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• 2019

Knowing the response of buildings to earthquakes is very important in order to ensure that a structure is able to withstand a given level of ground shaking. Thus, nonlinear dynamic earthquake engineering analyses are unavoidable and are preferable procedure in the seismic assessment of buildings. In order to estimate seismic performance on the basis of the hazard at the site where the structure is located, the selection of appropriate seismic input is known to be a critical step while performing this kind of analysis. In this paper, seismic analysis is performed for a four-story reinforced concrete ISPRA frame structure which is designed according to Eurocode 8 (EC8). A total of 90 different earthquake scenarios were selected, 30 for each of three target spectrums, EC8 spectrum, Uniform Hazard Spectrum (UHS), and Conditional Mean Spectrum (CMS). The aim of this analysis was to evaluate the average maximum Inter-story Drift Ratio (IDR) for each target spectrum. Time history analysis for every earthquake record was obtained and, as a result, IDR as the main measure of damage were presented in order to compare with defined performance levels of reinforced concrete bare frames.

• International Journal of Advanced Culture Technology
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• v.9 no.1
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• pp.121-128
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• 2021

In this study, we aim to suggest direction for landscape design of residential complex in Korea by studying target areas to understand how landscape urbanism was applied to residential landscape design as it is the majority of landscape design in Korea and by closely examining design elements to be considered for design of residential complex based on landscape urbanism theory. For the purpose of the study, some of public multifamily housing complex were selected as target areas and a survey was first conducted to understand how landscape urbanism was applied to design of these target areas. Then, by analyzing the survey results, we identified which elements were of importance to designing of multifamily housing complexes in Korea and how practical design of landscape urbanism works. From this study, we concluded that landscape urbanism theory is not just about design strategies, but more of comprehensive design methodology covering both operation and management and that such theory can be appropriately applied to design of multi-housing complexes in Korea. We also discovered that in order to apply landscape urbanism in design stage for multi-housing complex, selecting which design strategy/words in the previous study is not what's important, but comprehensive understanding and interpretation of design languages is key.