• Journal of Sasang Constitutional Medicine
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• v.22 no.1
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• pp.1-8
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• 2010

1. Objectives: This study was performed to research the relationship between Sasang Constitution and characteristics of tongue diagnosis based on Donguisusebowon's Experience prescriptions(經驗方). 2. Methods: We searched tongue diagnosis factors in Donguisusebowon and classified this. Based on Donguisusebowon's Experience prescriptions(經驗方), we find tongue diagnosis factors in 6 contemporary Oriental medicine prescription books. 3. Results: Most So-eumin has white thin tongue coating and clear redish tongue color. Yellow tongue coatings are found in symptoms for Yinjinho-tang(Yinchenhao-tang), Soseungki-tang(Xiaochengqi-tang), Daeseungki-tang(Dachengqi-tang). Shortened Tongue is found in So-eumin's experience prescription and So-yangin's treat histroy. It didn't shown that So-eumin's Semen Crotonis included 6 prescritions' factors of tongue diagnosis. So-yangin's white tongue coating is found in Hyungbangpaedok-san(Jingfangbaidu-san), Sipjo-tang(Shizao-tang), Sosiho-tang(Xiaocihu-tang), Shinki-hwan(Shenqi-wan). Most of other So-yangin's tongue coatings are Yellowish and tongue color is deep red. Tae-eumin have thin white tongue coating at the Mahuang-tang(Mahuang-tang). Red tongue color and drying tongue are found at Jowiseungki-tang(Tiaoweichengqi-tang)Daesiho-tang(Dacihu-tang)Saengmaek-san(Shengmai-san) 4. Conclusions: Following So-eumin's Experience prescriptions, So-eumin's tongue color is clear red and tongue coatings are thin white and greasy. Following So-yangin's Experience prescriptions, So-yangin's tongue color is deep red and tongue coatings are yellowish and scarce except Exterior cold disease. And So-yangin has specific symptom of irritability, oral sores. Tae-eumin's tongue has two sides of white thin tongue coatings and Red and drying tongue.

• Journal of Korean Medical classics
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• v.33 no.1
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• pp.51-60
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• 2020

Objectives : To compare the herbal ingredients of the prescriptions in 「Newly Selected Twenty-four Key Formulas applied to Tae-eumin(新定太陰人病應用要藥二十四方)」 chapter of the Shinchuk edition of the 『Donuisusebowon』 and those from the texts of the Four Great Doctors of the Jin Yuan period. Methods : The herbal ingredients of the 『Donuisusebowon』 and those from 『Huangdisuwen Xuanminglunfang(黃帝素問宣明論方)』, 『Lanshimicang(蘭室秘藏)』, 『Suwenbingji Qiyibaomingji(素問病機氣宜保命集)』, 『Shanghan Biaoben Xinfaleicui(傷寒標本心法類萃)』, 『Piweilun(脾胃論)』, 『Neiwai Shangbianhuolun(內外傷辨惑論)』, 『Shanghanzhige(傷寒直格)』, 『Shanghanxinyao(傷寒心要)』, 『Sanxiaolun(三消論)』 were entered into the database. Next, formulas which included the herbal combination pattern of Tae-eumin formula were determined. Results : Among the 27 Tae-eumin formulas including edited versions, those that showed similar pattern among those in the JinYuan texts were the following 12: Gegenjiejitang(葛根解肌湯), Reduohanshaotang(熱多寒少湯), Gegenchengqitang(葛根承氣湯), Gegentaichengqitang(葛根大承氣湯), Gegenshaochengqitang(葛根小承氣湯), Mahuangpobiaotang(麻黃發表湯), Bufeiyuantang(補肺元湯), Zaojiaodahuangtang(皂角大黃湯), Guadisan(瓜蒂散), Shexiangsan(麝香散), Shichangpuyuanzhisan(石菖蒲遠志散), Maimundongyuanzhisan(麥門冬遠志散). Conclusions : Based on the finding that 44.4% of the Shinchuk edition's Tae-eumin formula patterns could be found in the texts of the Four Masters, Dongmu's assertion that about half of the Tae-eumin formulas has been clarified by the doctors of the Song, Yuan, Ming eras could be understood as true.

• Journal of Physiology & Pathology in Korean Medicine
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• v.24 no.5
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• pp.790-795
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• 2010

Sasang Constitution Medicine(SCM)'s researches have been developed in many ways, especially Herbal medicine prescriptions and diagnosis. But there are no acceptable acupuncture theory for the Sasang Constitution. So We have tried to find the way for identifying each Sasang Constitution's acupuncture point on more reasonable methods. We studied that SCM acupuncture based on collecting Books of "Shanghanlun(傷寒論)", or Six-meridian pattern identification's acupuncture prescription. Selected books are "The Acupuncture and Moxibustion(침구학)", "Zhonghua Zhenjiuxue(中華鍼灸學)", "Zhenjiuxinchuan(鍼灸心傳)", "Shanghanlun Zhenjiupeixuexuanzhu(傷寒論鍼灸配穴選注)". So-eumin uses Conception Vessel's acupuncture points most frequently. And So-yangin and Tae-eumin use Bladder meridian and Stomach meridian's acupuncture points most. Moxibustion is used many times for So-eumin, especially at three Yin-Symptoms(三陰病). Orders for using frequencies of three Sasang constitutions' acupuncture points are: So-eumin uses ST36 CV12 CV4 most, So-yangin uses PC6 ST36 LI4 most, Tae-eumin uses ST36 LU7 CV12 most. Acupuncture for Sasang constitutions has been developed for many ways, but there are no generally acceptable theory. So we need to hold a committee for SCM and acupuncture specialist to establish acceptable and reasonable SCM acupuncture theory.

• The Journal of Korean Medicine
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• v.32 no.5
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• pp.12-24
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• 2011

Objectives: This study analyzed literature published in Korea using Tae-eumin prescriptions and herbs for obesity for future research. Methods: We conducted a computerized search at journal web sites and manual searches. A total of 25 sites were included. Obesity, obese, over weight, herb, herbal, taeum, taeyuem, and taeeum were selected keywords and they were combined properly. Results:A total of 28 studies were analyzed. The percentage of clinical and case report studies was 35.7% and experimental studies 64.3%. The most frequently used prescription was Taeeumjowui-tang (太陰調胃湯) and herbs were Raphani semen(蘿葍子) and Platycodon grandiflorum(桔梗). Weight (kg), body mass index (BMI) and side effects and symptoms were used as indices in clinical and case report studies. Weight, weight gain percentage and blood serum lipid profiles were frequently used as indices in experimental studies. Conclusion: Further well-designed randomized controlled studies and clinical reports of side effects and symptoms are needed for development of obesity studies for Tae-eumin prescriptions.

• Journal of Sasang Constitutional Medicine
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• v.21 no.2
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• pp.96-106
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• 2009

1. Objectives : The aim of this study was to survey the ordinary symptoms of TE type(Tae-eumin) and to compare the tendency of their symptoms according to the Exterior- or Interior- disease. 2. Methods : We recruited 659 TE type(Tae-eumin)-subjects in multi-oriental hospitals and researched their ordinary symptoms. Subjects were diagnosed by the Sasang Constitutional specialists in oriental hospitals, and had remarkable improvement in the chief complains after Sasang Constitutional Medication. Subjects were divided two groups. One group had the Exterior-cold disease and they took the prescription for the Exerior-cold disease(such as Taeumjowi-tang, Jowiseungcheong-tang, Nocyongdaebo-tang etc.). The other group had the Interior-febrile disease and they took the prescription for the Interior-febrile disease(such as Galgunhaegui-tang, Yeoldahanso-tang, Cheongsimyeonja-tang, Gongjinhugwon-dan etc.). All subjects answered the questionnaire about their symptoms. We found the differences of answers using the Chi-square test between-group comparisons. We analyzed using SPSS 12.0 for Korean. 3. Results and Conclusions : In symptoms, Quantity of meal(p=.009), Perspiration of head and face(p=.001), Aspect of Excrement(p=.027), Presence of pain after excrement(p=.001), Frequency of urination at night(p=.003), Clarity of urine(p=.041), Sleep during the day(p=.049), Warm or cold feeling on abdomen(p=.007), etc. are different according to the Exterior- or Interior- disease. We found the differences of symptoms between not only the constitutional types but also the types of disease.

• Journal of Physiology & Pathology in Korean Medicine
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• v.28 no.1
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• pp.53-58
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• 2014

The object of this study was to evaluate the single dose toxicity of Choweseuncheng-tang (CWS), a polyherbal formula have been traditionally used as prevention or treatment agent for various diseases as Tae-eumin prescription on Korean medicinal theory, Sasang-euihak, in male and female mice. Aqueous extracts of CWS (yield = 11.00%) was administered to female and male mice as an oral dose of 2,000, 1,000 and 500 mg/kg (body weight) according to the recommendation of Korea Food and Drug Administration (KFDA) Guidelines. Animals were monitored for the mortality and changes in body weight, clinical signs and gross observation during 14 days after dosing, upon necropsy; organ weight and histopathology of 14 principle organs were also examined. As results, we could not find any CWS treatment related mortality and clinical signs, changes in the body and organ weights, gross findings and changes in histopathology of principle organs, except for some dose-independent accidental findings. The results obtained in this study suggest that the 50% lethal dose and approximate lethal dose of CWS aqueous extracts in both female and male mice were considered as over 2,000 mg/kg, the limited highest dosage recommended by KFDA Guidelines, and can be safety used in clinics.

• Journal of Sasang Constitutional Medicine
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• v.22 no.1
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• pp.9-16
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• 2010

1. Background: GalgeunNabokja-Tang(葛根蘿葍子湯) is suggested as treatment and prescription of Exterior Heat syndrome Diarrhea(表熱證泄瀉) in Donguisusebowon Tae-eumin Interior febrile disease induced form the liver affected by heat("東醫壽世保元" "太陰人肝受熱裏熱病論"), but is not recorded the treatment contents in Sinjungbang("新定太陰人病應用要藥二十四方"). 2. Methods: Accordingly, the writer surveyed, compared, and arranged the relevant contents by collecting books of doctors of Four-Constitutional Medicine(四象醫) since Lee Je-ma including Lee Je-ma's books. 3. Results: and Conclusions: 1) The treatment contents in GalgeunNabokja-Tang are thought to be valid to have the criterion as the contents of appearing in SanggyohyuntoDonguisusebowon Boyubang("詳校懸吐東醫壽世保元" "補遺方"). 2) The origin in GalgeunNabokja-Tang is GalgeunNabokja-Tang in Bimang-lok("備忘錄"). And the period of having made treatment for the first time may be estimated to be the one between Donguisuse- bowonSasangchobonguan("東醫壽世保元四象草本卷") and HamsansachonDonguisusebowonGabogubon ("咸山沙村東醫壽世保元甲午舊本"). 3) GalgeunNabokja-Tang is thought to be probably what Han Du-jeong recorded in Boyubang by searching for what Lee Je-ma modified some of GalgeunNabokja-Tang in Bimang-lok while writing Pathological Syndromes("病證論") in Donguisusebowon("東醫壽世保元").

• Journal of Sasang Constitutional Medicine
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• v.24 no.4
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• pp.75-83
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• 2012

Objectives : Although Yeoldahanso-tang (YDHST) has been widely used for treatment of obesity and its related diseases such as hyperinsulinemia and hypertension for Taeeumin, no scientific evidence has reported yet to support its ability to work against these metabolic disorders. Our study was aimed to investigate the anti-obesity effect of YDHST extract on the cellular differentiation of 3T3-L1 preadipocytes into adipocytes. Methods : 3T3-L1 preadipocytes were differentiated into adipocytes by adding insulin, dexamethasone and 3-isobutyl-1-methylxanthine (IBMX) for 8 days in the absence or presence of YDHST extract. Anti-obesity effects of YDHST extract were evaluated by Oil Red O staining, glycerol-3-phosphate dehydrogenase (GPDH) activity, triglyceride contents, and leptin production. Results : YDHST extract remarkably prevented lipid accumulation with no cytotoxicity in the differentiated 3T3-L1 cells. In addition, YDHST extract decreased contents of triglyceride 3T3-L1 adipocytes. Consistently, YDHST extract caused a significant inhibition of GPDH activity and leptin production in a dose-dependent manner. Conclusions : Our findings suggest that Sasang constitutional herbal formula YDHST for Tae-eumin has anti-obesity activity by regulation of the adipogenesis process in vitro. Additional study will be required to further confirm the inhibitory effect on adipocyte differentiation by using in vivo animal model.