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Direct Effect of a Hot Environment on Ruminal Motility in Sheep

  • Sunagawa, Katsunori;Arikawa, Yuji;Higashi, Mika;Matsuda, Hiroshi;Takahashi, Hiroshi;Kuriwaki, Zyunichi;Kojiya, Zuikou;Uechi, Syuntoku;Hongo, Fujiya
    • Asian-Australasian Journal of Animal Sciences
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    • v.15 no.6
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    • pp.859-865
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    • 2002
  • The aim of this research was to clarify the direct effects of a hot environment on ruminal motility in sheep fed twice a day. In the first experiment, in order to equalize variable factors excluding the ambient temperature between the thermoneutral environment ($23^{\circ}C$, relative humidity 80%) and the hot environment ($32^{\circ}C$, relative humidity 80%), sheep were fed equal amounts of the same quality feed twice a day. The sheep were allowed free access to water for the duration of the two one-hour feeding periods (10:00 am-11:00 am, 5:00 pm-6:00 pm). On the fourth day after exposure to the hot environment, the frequency and strength of ruminal contractions were continuously recorded between 9:30 am and 11:00 pm. Prior to the exposure to a hot environment the frequency and strength of ruminal contractions were recorded in a thermoneutral environment during the period 9:30 am-11:00 pm. In the second experiment, in order to maintain the stomach content of the sheep at equal levels in both environments, the sheep were fed equal amounts of the same quality feed twice a day. Following the completion of the two one-hour feeding periods, a fixed amount of warm water was infused into the rumen. Rumen motility was then recorded during the same period as for the first experiment (9:30 am-11:00 pm). In the first experiment, when the frequency of ruminal contractions prior to (24, 24 frequency/15 min), during (48, 47 frequency/min) and after (22, 19 frequency/min) both the morning and afternoon feeding in a hot environment was compared with the values from the thermoneutral environment (20, 22; 50, 50; 21, 20 frequency/min), there was found to be no difference. However, the strength of ruminal contractions after morning and afternoon feeding (3.7, 3.1 mm Hg) in the hot environment decreased significantly in comparison with the thermoneutral environment (4.3, 3.8 mm Hg). In the second experiment, the frequency of ruminal contractions in the hot environment was not significantly different from that in the thermoneutral environment. The strength of ruminal contractions after ruminal infusion of warm water in the hot environment (morning: 4.6, afternoon: 4.5 mm Hg) was significantly lower than that in the thermoneutral environment (morning: 5.6, afternoon: 5.0 mm Hg). The results suggest that a hot environment acts directly on the strength of ruminal contractions in sheep fed twice a day rather than on the frequency.

The Efficacy and Safety of Moclobemide Twice Daily : An Open Trial in Patients with Major Depressive Disorder (1회 2회 분복 투여하는 Moclobemide의 효과와 안전성 : 주요우울장애 환자에서 개방 시험)

  • Yoon, Jin-Sang;Lee, Hyung-Young;Kook, Seung-Hee;Choi, Young
    • Korean Journal of Biological Psychiatry
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    • v.3 no.1
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    • pp.102-108
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    • 1996
  • This was an open trial to evaluate the efficacy and safety of moclobemide twice daily for treatment of Korean patients with major depressive disorder(DSM-III-R). The duration of the trial was 6 weeks with the initial dose of moclobemide being fixed lor the first two weeks at 300mg/day(150mg twice daily, each token after morning and evening meals). Thereafter, when necessary, the dose was allowed to increase to 600mg/day or decrease to 150mg/day according to the seventy of the depression and/or the tolerability of the drug. Hypnotics and/or sedatives from a benzodiazepine group could be concomitantly administered at usual dosage. Patients were assessed at baseline and at days 14, 28 and 42. Efficacy was primarily judged on the Hamilton Rating Scale for Depression(HAM-D) and Beck Depression Inventory(BDI). Patients had to score at least 17 respectively an both scales to enter the trial. Secondary efficacy parameters included Clinical Global Impression(CGI) for severity of illness and improvement. Safety and tolerability were judged on reported adverse events, vital signs and laboratory parameters. In addition, there was a series of questions and assessments for the psychiatrists and patients to complete at the end of the trial Twenty nine patients completing trial were included in the analysis of efficacy : of thirty one patients participating in the safety and tolerability analysis, those who withdraw voluntarily without particular reasons or violated the treatment schedule were not included. The efficacies as determined by HAM-D, BDI or CGI were found to be significant compared to baseline. The number of responders defined as patients with a total score of 10 or less or with a total score of 50% or less of the baseline score on HAM-D and BDI were 17(59%) and 18(62%) respectively. Regarding safety and tolerability, nine patients(29%) reported mild adverse events probably related to moclobemide : of these one patient dropped out because of poor tolerability : however, there were no appreciable changes in blood pressure, pulse rate, body weight or laboratory parameters for all patients over the trial period. Furthermore, the physicians' and patients' opinions at final evaluation showed that moclabemide has a good antidepressant effect as well as a favorable tolerability. In conclusion, a twice-daily dosage schedule with maclobemide is recommendable for the treatment of Korean patients with major depressive disorder since its efficacy and safety were demonstrated in this study.

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Amino Acid Composition of Human and Cow's Milk (모유 및 우유의 아미노산 조성에 관한 비교연구)

  • 고영수
    • Journal of the Korean Home Economics Association
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    • v.24 no.4
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    • pp.51-55
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    • 1986
  • The composition of human milk was compared with that of cow's milk. The contents of amino acids were analyzed by amino acid autoanalyzer. The content of glutamic acid in cow's milk was three times as much as that in human milk. The content of essential amino acid in human colostrum was twice as much as that in mature milk.

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A Case Study of Continuous Explosives Demolition at Han Kuk Flour Mills Silo (한국제분 SILO 연속적 발파해체 시공사례)

  • Song, Young-Suk;Jeong, Min-Su;Heo, Eui-Haeng;Jung, Dong-Wol
    • Explosives and Blasting
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    • v.30 no.2
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    • pp.77-85
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    • 2012
  • This is the study about continuous explosives demolition to Han Kuk Flour Mills Silo(14 units) located in Mokpo. Considering the surroundings, We planned to collapse toward longitudinal direction of the silo. It had a lot of blast hole per silo in confined space. It could make lots of problems like Cut-off, collapse behavior, fragmentation after structure behavior. So we separated 14 units silo to two section for blast twice. At the first A-Section blast, there was Cut-off of detonating cord and we had to blast twice to collapse remained silo. After that the secondary B-Section blasting, we got the desired result of collapse behavior.

Analysis of Morphology and Viscoelastic Behavior of LCP/PET Blends by Repeated Extrusion (반복압출에 의한 LCP/PET 블렌드 조성에 따른 모폴로지 및 점탄성 거동 분석)

  • Choi, Yong Seok;Jeon, Han-Yong
    • Polymer(Korea)
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    • v.39 no.3
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    • pp.475-479
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    • 2015
  • Droplet distribution of LCP(Vectra 950) and PET blend by repeated extrusion was examined through morphology analysis. Repeated extrusion was respectively proceeded twice and three times with blending condition and droplet distribution of only once extrusion sample showed uniform shape. However, droplet size of twice and three times extrusion samples increased and it was confirmed that droplets were concentrated on the center of specimens. It is thought that this phenomena were due to the compatibility and viscoelastic behavior of LCP/PET blend. Finally, it is thought that fiber manufacturing of different diameter is possible from spinning of repeated extrusion LCP/PET blended chip under same spinning condition.

Kaposi's Varicelliform Eruption in Atopic Dermatitis treated with Korean medicine

  • Lee, Dong-Jin;Kwon, Kang;Sun, Seung-Ho;Seo, Hyung-Sik
    • Journal of Pharmacopuncture
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    • v.17 no.2
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    • pp.80-83
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    • 2014
  • Objectives: This case report is to present a complete recovery from Kaposi's varicelliform eruption (KVE) that occurred in a patient with atopic dermatitis by applying Korean Medicine therapies. Methods: Hwangyeonhaedoktang pharmacopuncture (HP), 0.3 mL, and 25% bee venom pharmacopuncture (BVP), 0.1 mL, were injected, 0.2 mL each, at both BL13 acupoints once a day in the morning. Acupuncture was applied at Sama Upper, Middle and Lower of the Master Tung acupuncture points and at ST44 on the left lateral for 30 minutes twice a day. The affected face was gauze dressed with mixture of 2.0 mL HP and 1.0 mL 25% BVP with 20 mL of normal saline twice a day. Herbal Medicine, Seungmagalgeuntang, was administered three times a day after each meal. Results: Rashes and papules on the face were completely cleared after 10 days of treatments. Conclusion: KVE, an acute and urgent dermatitis, can be effectively treated with Korean medicine.

Effect of Frequency of Meals on Intake and Digestion of Tropical Grass Consumed by Rams

  • Assoumaya, C.;Sauvant, D.;Pommier, F.;Boval, M.;Calif, B.;Archimede, H.
    • Asian-Australasian Journal of Animal Sciences
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    • v.22 no.1
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    • pp.72-81
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    • 2009
  • Eight Black Belly rams (45.2 kg) fitted with permanent ruminal cannulae were used in a 2${\times}$2 factorial design to determine the effects of feeding frequency and regrowth age on intake and digestion. Rams were fed with 21- or 35-day old fresh pangola grass offered ad libitum two or four times a day. Irrespective of the regrowth age, there was a tendency for intake to be positively correlated with increase in meal frequency. Differences were not significant (p>0.25). Significant effects of meal frequency were observed in NDF and ADF total tract digestibility of the 35-day grass which decreased as the number of meals increased. Meal frequency had no visible effect on feeding behaviour. Total rumen content increased when animals were fed twice a day as opposed to four times a day. Similarly, an accumulation of small and very small particles was observed in the rumen of rams fed twice a day in comparison with those fed four times a day. These results suggest that studies of digestive dynamics performed at a steady state are not representative of the rumen loading observed in farm rams which have two important peaks of meal.

A Case Report about Pregnancy and Delivery with Primary Amenorrhea by Oriental Medicine in Oocyte Donation (원발성 무월경 환자의 난자공여 시술시 한약치료를 병행한 임신 및 출산 1례)

  • Koh, Ji-Eun;Lyou, Myung-Sook
    • The Journal of Korean Obstetrics and Gynecology
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    • v.30 no.2
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    • pp.144-152
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    • 2017
  • Objectives: The aim of this case is to report the effects of oriental medicine on one patient with primary amenorrhea for endometrial preparation and implantation. Methods: A patient with primary amenorrhea had symptoms of sleep disorder, diarrhea, colpoxerosis. For preparing endometrium and implantation in oocyte donation after one previous failure, she was treated by twice a day herb medication for 75 days. And we observed the effects of treatments by improvement of symptoms and following up endometrial proliferation ultrasonography. After implantation, for maintaining pregnancy and live birth, she was also treated by twice a day herb medication for 45 days. Results: After treatments, Symptoms of sleep disorder, diarrhea, colpoxerosis were improved and the thickness of endometrium was prepared for implantation in oocyte donation. So she was pregnant and gave birth to a healthy baby 36 weeks later. Conclusions: This case shows that oriental medicine has its effective implementation for the implantational surroundings on patients with primary amenorrhea in oocyte donation programs.

Seismic Design of Steel Frame Model Considering the Panel Zone and Viscous Dampers (패널존과 점성감쇠기를 고려한 강골조 구조물의 내진 설계 모델)

  • Park, Sun-Eung;Lee, Tack-Woo
    • Journal of Korean Association for Spatial Structures
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    • v.20 no.2
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    • pp.87-94
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    • 2020
  • The present study is aimed to calculate the optimal damping according to the seismic load on the structure with a non-seismic design to perform structure analysis considering the deformation of structural joint connection and panel zone; to develop design program equipped with structural stability of the steel frame structures reinforced with the panel zone and viscous dampers, using the results of the analysis, in order to systematically integrate the seismic reinforcement of the non-seismic structures and the analysis and design of steel frame structures. The study results are as follows: When considering the deformation of the panel zone, the deformation has been reduced up to thickness of the panel double plate below twice the flange thickness, which indicates the effect of the double plate thickness on the panel zone, but the deformation showed uniform convergence when the ration is more than twice. The SMRPF system that was applied to this study determines the damping force and displacement by considering the panel zone to the joint connection and calculating the shear each floor for the seismic load at the same time. The result indicates that the competence of the damper is predictable that can secure seismic performance for the structures with non-seismic design without changing the cross-section of the members.

Intelligent Diagnosis of Broken Bars in Induction Motors Based on New Features in Vibration Spectrum

  • Sadoughi, Alireza;Ebrahimi, Mohammad;Moallem, Mehdi;Sadri, Saeid
    • Journal of Power Electronics
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    • v.8 no.3
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    • pp.228-238
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    • 2008
  • Many induction motor broken bar diagnosis methods are based on evaluating special components in machine signals spectrums. Current, power, flux, etc are among these signals. Frequencies related to a broken rotor fault are slip dependent, therefore, correct diagnosis of fault - especially when obtrusive frequency components are present - depends on accurate determination of motor velocity and slip. The traditional methods typically require several sensors that should be pre-installed in some cases. This paper presents a diagnosis method based on only a vibration sensor. Motor velocity oscillation due to a broken rotor causes frequency components at twice slip frequency difference around speed frequency in vibration spectrum. Speed frequency and its harmonics as well as twice supply frequency, can easily and accurately be found in a vibration spectrum, therefore th motor slip can be computed. Now components related to rotor fault can be found. It is shown that a trained neural network - as a substitute for an expert person - can easily categorize the existence and the severity of a fault according to the features extracted from the presented method. This method requires no information about th motor internal and has been able to diagnose correctly in all the laboratory tests.