• Journal of Korean Society for Atmospheric Environment
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• v.14 no.1
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• pp.1-10
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• 1998

Relationships between TSP and PM10 concentrations were evaluated using their respective data sets collected from Taegu and Kyeungsan areas during the period of December 1993 to November 1994. The collection of data was made using the gravimetric and $\beta$-ray absorption ($\beta$-MPM) methods for 7 days of every month from three urban sites in Taegu and one suburban site in Kyeungsan. Correlation coefficients between TSP and PM10 concentrations for these four sampling sites were found in the range of 0.85 $\sim$ 0.96. Correlation analysis was also conducted for $\beta$-PM concentration data that were measured only from the residential and commercial sites. The correlation coefficients between TSP and $\beta$-PM concentrations were 0.9 in the residential site and 0.8 in the commercial site. By contrast, the correlation coefficients between PM10 $\beta$-PM concentrations were almost identical for both the residential and commercial sites with a value of 0.88. The mean ratio for PM10 to TSP concentrations for all sites was appeared to be 0.68. The analysis of seasonal trends in PM10/TSP ratios showed that the contribution of PM10 to TSP concentrations was more significant during winter (0.70 $\sim$ 0.75) than during summer (0.61 $\sim$ 0.68). The results of this study may provide empirical informations on the compatability of aerosol data measured by different sampling methods.

• Journal of Environmental Health Sciences
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• v.26 no.4
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• pp.1-8
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• 2000

The objective of this study was to identify the sources and to estimate the source contributions to the atmospheric TSP(total suspended particulate matter) and PM-10(particulate matter with aerodynamic diameters less than 10$\mu\textrm{m}$) concentration in Taegu area. A total of 84 samples was collected during the January to December 1999. TSP and PM-10 were collected on filters by portable air sampler, and heavy metals in TSP and PM-배 were analyzed by ICO(Inductively Coupled Plasma Spectrometery) after preliminary treatment. The results were follow as : First, annual average of TSP and PM-10 concentration was 123 and 69$\mu\textrm{g}$/㎥ respectively. The concentration of TSP and PM-10 were highest in winter season compared to other seasons. Second, the concentration of Al, Fe, Mn were higher in TSP than in PM-10, indicating that these heavy metals are generally associate with natural contributions. Third, metal combinations showed that a high correlation among concentrations of heavy metals were follows: As Al, Fe and Mn in TSP ; Ni, Cr, Cd and Pb in PM-10. Finally, Statistical analysis was performed using Principal Components Analysis(PCA) in order to find possible sources of the pollutants. The factor analysis was permitted to identify four major sources(soil/road dust resuspension, waste incineration, furl combustion, vehicular emission) in each fraction. These source accounted for at least 83, 85% of variance of TSP and PM-10 concentration in Taegu area.

• International Journal of Oral Biology
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• v.33 no.3
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• pp.105-111
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• 2008

Thrombospondins (TSP-1, TSP-2) are secretory extracellular glycoproteins that are involved in a variety of physiological processes such as tumor cell adhesion, invasion, and metastasis. The present study was undertaken to elucidate the involvement of thrombospondins in the adhesion of osteoblast-like cells using the TSP-1 or TSP-2 antisense MG63 and MC3T3-E1 cell lines. For downregulation of TSPs expression, we prepared antisense constructs for TSP-1 and TSP-2 using the pREP4 an episomal mammalian expression vector, which be able to produce the specific antisense oligonucleotides around chromosome. MG63 and MC3T3-E1 osteoblast-like cells were transfected with the antisense constructs and nonliposomal Fugene 6, and then selected under hygromycin B (50 ${\mu}g/ml$) treatment for 2 weeks. Western blot analysis revealed that expression of the TSP proteins was downregulated in the antisense cell lines. The cell adhesion assay showed that adhesive properties of TSP-1 and TSP-2 antisense MG63 cells on the polystyrene culture plate were reduced to 17% and 21% of the control cells, respectively, and those of the TSP-1 and TSP-2 antisense MC3T3-E1 cells also decreased to 19% and 27% of control, respectively. Adhesion of TSP-1 and TSP-2 antisense MC3T3-E1 cells on Type I collagen-coated culture plate decreased to 27% and 76%, respectively. These results indicate that TSP-1 and TSP-2 proteins may have an important role in adhesion of osteoblast-like cells to extracellular matrix.

• 한국지구물리탐사학회:학술대회논문집
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• 1999.08a
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• pp.117-136
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• 1999

The geophysical survey at pre-investigation stage can hardly provide the detailed information on geological structure of site which has difficulty in access and thick overburden. The TSP (VSP applied in tunnel) survey at post-investigation stage can show the detailed geology ahead of tunnel and around cavern. The TSP survey was carried out at the Pyongtaek LPG storage cavern site during the cavern excavation and provided the location and orientation of the fault inferred below Namyangho. In order to confirm the result of TSP survey four boreholes were drilled in access tunnel. The fault was also detected by borehole survey and the location was coincided with the result of TSP survey. Depend on the result of TSP survey and core logging, the design such as cavern layout and length could have been changed. As another case history the TSP survey was performed at the Mumeuje road tunnel which has poor geological information due to thick overburden. The support design was also changed on the base of TSP survey.

• Journal of Life Science
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• v.15 no.6 s.73
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• pp.895-903
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• 2005

Thrombospondin-1 (TSP-1), a negative regulator in tumor growth and angiogenesis, is cell-type specifically regulated under pathological conditions or by extracellular stimuli, and the regulation of TSP-1 gene expression is important for developing new approaches in tumor therapy. Mistletoe is a parasitir plant that have been used for immunomodulation and antitumor therapy. Helixor A is an aqueous part of mistletoes extract. Here we showed that TSP-1 expression was significantly induced at both mRNA and protein levels in the Hepatocarcinorna cell line (Hep3B) and primary bovine endothelial cell line (BAE) exposed to Helixor A. Our promoter analysis confirmed that the expression of TSP-1 gene was regulated by Helixor A at the transcriptional level. In cell invasion assay, the conditioned media obtained from treatment of these cells significantly reduced the number of invasive cells and also inhibited capillary-like tube formation of BAE cells on Matrigel. Moreover, the inhibitory efforts of the conditioned media on cell invasion and tube formation were reversed by blocking with anti-TSP-1 neutralizing antibodies, suggesting that TSP-1 is involved in Helixor A-indured antiangiogenic effect. Taken together, our results suggest that Helixor A have an antiangiogenic effects through upregulation of TSP-1.

• Proceedings of the Acoustical Society of Korea Conference
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• spring
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• pp.236-239
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• 1999

Target signal feature parameters are very important to classify target by active sonar. Two highly correlated broadband pulses separated by time T have a time separation pitch (TSP) of 1/THz, equal to the spacing between ripples of its spectrum. In this study, TSP is applied to scaled-target echoes to be used as a feature parameter. The TSP from the target sign리 when source signals are CW short, CW long, and LFM long was investigated. It is also found the TSP can be applied to the target signal with doppler shift. It is shown that the position and magnitude of highlight can be found for LSEM based on TSP.

• YAKHAK HOEJI
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• v.53 no.3
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• pp.151-155
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• 2009

Meteorin in astrocytes has antiangiogenic activities via thrombospondin-1 (TSP-1), however, the regulatory mechanism has been unclear. Here we report that Meteorin upregulates TSP transcriptionally through luciferase reporter assays in astrocytes. Moreover, Meteorin activates $PKC\delta$ and ERK1/2 in astrocytes. Inhibition of $PKC\delta$ and ERK1/2 activities attenuated expression of TSP-1 by Meteorin in astrocytes. We, therefore, demonstrate that Meteorin activates $PKC\delta$ signaling and, in turn, increases TSP-1 expression in astrocytes to inhibit angiogenesis in the brain.

• Proceedings of the Korea Information Processing Society Conference
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• 2006.05a
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• pp.273-276
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• 2006

CMM/CMMI 와 같은 프로세스 모델의 등장으로 소프트웨어 프로세스 개선에 대한 원리와 방법은 인식하였으나 현실에 적용하여 성과를 창출하기에는 상당한 어려움을 겪어왔다. 이러한 문제를 해결하고 개발자와 개발팀 차원에서 CMM/CMMI 의 목표와 프렉티스를 구현하기 위해 SEI(Software Engineering Institute)에 의해 PSP/TSP 가 개발되었다. 이렇게 PSP/TSP 가 개인과 팀차원에서 소프트웨어 개발에 사용될 수 있는 구체적인 기법들을 기술하고 있지만 일반적으로 PSP/TSP 에서 수집되는 메트릭에 대한 분석기법은 여전히 부족하다. 따라서 PSP/TSP 수행시 발생할 수 있는 문제를 방지하고 프로세스가 변경되고 유지 관리될 수 있도록 하기 위해서는 6 시그마의 다양한 통계 기법과 의사 결정도구의 사용이 필요하다. PSP/TSP 는 6 시그마가 성공적으로 적용될 수 있는 정량적인 기반을 개인과 프로젝트 차원에서 제공한다. 이에 대해 6 시그마는 PSP/TSP 에서 식별된 문제의 원인을 파악하고 분석하기 위해 필요한 분석도구와 통계적 기법을 제공하고, 문제를 방지하기 위해 프로세스가 변경되고 유지 관리될 수 있는 프로세스 관리 방법론을 제공한다. 따라서 본 논문에서는 PSP 의 각 프로세스에서 활용될 수 있는 6 시그마 도구를 식별하고 활용 가이드라인을 제시함으로써 개인과 팀 차원에서의 프로세스 개선의 수행을 지원하며 팀 차원에서 발생할 수 있는 이슈를 6 시그마의 분석, 정량화 도구를 사용하여 개인 또는 팀의 성과를 향상할 수 있는 방법을 모색해본다.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.10 no.3
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• pp.622-627
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• 2006

TSP(Traveling Salesman Problem) is a problem finding out the shortest distance out of many courses where given cities of the number of N, one starts a certain city and turns back to a starting city, visiting every city only once. As the number of cities having visited increases, the calculation rate increases geometrically. This problem makes TSP classified in NP-Hard Problem and genetic algorithm is used representatively. To obtain a better result in TSP, various operators have been developed and studied. This paper suggests new method of population initialization and of sequential transformation, and then proves the improvement of capability by comparing them with existing methods.

• Journal of the Korean Institute of Intelligent Systems
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• v.14 no.1
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• pp.105-111
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• 2004

DNA computing has been using to solve TSP (Traveling Salesman Problems). However, when the typical DNA computing is applied to TSP, it can`t efficiently express vertices and weights of between vertices. In this paper, we proposed ACO (Algorithm for Code Optimization) that applies DNA coding method to DNA computing to efficiently express vertices and weights of between vertices for TSP. We applied ACO to TSP and as a result ACO could express DNA codes which have variable lengths and weights of between vertices more efficiently than Adleman`s DNA computing algorithm could. In addition, compared to Adleman`s DNA computing algorithm, ACO could reduce search time and biological error rate by 50% and could search for a shortest path in a short time.