• Korean Journal of Environmental Biology
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• v.22 no.1
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• pp.177-183
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• 2004

Cytochrome P45O (CYP) contents and 7-ethoxyresorufin-O-deethylase (EROD) activity were determined in hepatic microsome of olive flounder (Paralichthys olivaceus) exposed to tributyltin chloride (TBTC), tributyltin oxide (TBTO), and triphenyltin chloride (TPTC). In addition, effects of in vivo (intraperitoneal injection of 7.5 mg $kg^{-1}$ BW) exposure of flounder to TPTC on CYP, NADPH cytochrome c reductase, NADH cytochrome b5 yeductase and EROD levels were measured. In in vitro exposure of hepatic microsome to organotins, TBTC, TBTO and TPTC reduced CYP contents and inhibited EROD activity. The TPTC was the strongest inhibitor, which is followed by TBTO and TBTC. The degree of inhibition, especially EROD acitivity, depended on the exposure duration. In addition, all the target enzymes in flounder were inhibited by TPTC with the in vivo exposure to TPTC. As EROD activity was the most sensitive to the inhibitions and demonstrated good reproducibility of the results, it could be used as a helpful tool toy monitor effects of organotin compounds on mixed funciton oxygenase system in marine fish.

• The Journal of Korean Academy of Prosthodontics
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• v.46 no.6
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• pp.553-560
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• 2008

STATEMENT OF PROBLEM: Proximal contact plays an important role in the stability and maintenance of the integrity of the dental arches. However, it is difficult to evaluate quantitatively the tightness of proximal tooth contact (TPTC). PURPOSE: The aim of this study was to measure the TPTC in permanent dentition. MATERIAL AND METHODS: Ten young adult volunteers with healthy dentition participated in this experiment. The TPTC between the teeth of both the maxilla and the mandible was measured at rest state by a novel device which records the TPTC by pulling of a stainless steel strip (0.03 mm thick) using the electric motor. One-way ANOVA test was used to compare the values in all measured area. When a statistically significant difference was calculated, Bonferroni correction was applied. Independent samples t-test was used to compare the values in male and female. RESULTS: The lowest TPTC and the highest TPTC was measured between the lower central incisors (0.87 ${\pm}$ 0.20 N), and between the lower left first molar and second molar (1.99 ${\pm}$ 0.68 N), respectively. All TPTC per quadrant demonstrated a similar pattern of a continuous increased gradient in an anterior-posterior direction. There are no significant difference between the maxilla and mandible. CONCLUSION: The TPTC was measured quantitatively by a novel device and decreased progressively in a posterior-anterior direction.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.35 no.2
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• pp.185-190
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• 2002

This study was carried out to measure the in vitro interaction of trialkyltin with the microsomal monooxygenase (MFO) system of the clam, Coelomactra antiquata. Cytochrome P450 (CYP) level and 7-ethonvesorufin-O-deethylase (EROD) activity were invetigated in the microsome isolated from digestive gland of the clam (C. antiquata) exposed to tributyltin chloride (TBTC), bis-tributyltinoxide (TBTO) and triphenyltin chloride (TPTC). The specific contents of CYP in clam microsome exposedto 0.4 mM TBTC, TBTO and TPTC for 20 minutes were decreased 52, 72 and $40\%$, respectively, compared to control group. The EROD activities also were inhibited by exposure to TBTO ($92\%$) and TPTC ($85\%$) except for TBTC, The level of CYP and the EROD actintles were decreased according to the OTC exposure concentrations. The toxic effects on the level of CYP and the EROD activities were in order of TPTC>TBTC>TBTO in this study. The measurement of CYP level and EROD activity could be applied as a biomarker for environmental study.

• Proceedings of the Korea Society of Environmental Biology Conference
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• 2001.12a
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• pp.119-120
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• 2001

• Proceedings of the Korea Society of Environmental Biology Conference
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• 2001.12a
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• pp.117-118
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• 2001

• Journal of Dental Rehabilitation and Applied Science
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• v.28 no.3
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• pp.233-243
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• 2012

The aim of this study was to evaluate time serial change of the TPTC(Tightness of Proximal Tooth Contact) between the implant prosthesis and natural tooth at rest state. Thirty-one patients(19 males and 12 females; mean age, 48.2 years) restored with a total 31 single-implant crowns in the left maxillary for 13 single-implant and left mandibular second molars for 18 single-implant crowns, respectively were selected. The TPTC was checked directly after delivery, 1 month after delivery and 6 months after delivery of prothesis at rest state. The TPTC decreased significantly as time goes by both maxilla(p<.01) and mandible(p<.05). The TPTC between the implant prosthesis and natural tooth decreased as time goes by after fixed implant prothesis placement.

• Korean Journal of Environmental Biology
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• v.21 no.2
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• pp.158-163
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• 2003

This study was conducted te evaluate the effect of organotin compounds on rotifer(Brachionus plicatilis), which is important as food organism of aqua-cultured fish and shellfish. To evaluate the texicities of tributyltin compounds such as tributyltin chloride (TBTC), tributyltin oxide (TBTO), tributyltin acetate (TBTA) and tributyltin benzoate (TBTB), and triphenyltin compounds such as triphenyltin chloride (TPTC), triphenyltin fluoride (TPTF), triphenyltin hydroxide (TPTB), the survival rates of rotifer exposed to these compounds were measured as the 96 hr-$LC_{50}$. Exposed concentrations Were from 0.5 to 8 bbp depending on compounds. Based on 96 hr-$LC_{50}$ Value, the Order of toxicity in TBTs was TBTA(1.1 ppb)>TBTC (2.0)>TBTB (3.3)>TBTO(5.6), and that in TPTs was TPTF (1.0)$\geq$TPTC(1.1)>TPTH(1.6). Triphenyltin compounds were slightly higher toxic than tributyltins. The toxicity is likely to depend on alkyl or aryl group other than halogen or the other substituted radicals.

• Proceedings of the Korean Society of Fisheries Technology Conference
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• 2002.05a
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• pp.486-487
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• 2002

• Proceedings of the Korea Society of Environmental Biology Conference
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• 2001.12a
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• pp.109-110
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• 2001

• Journal of Dental Rehabilitation and Applied Science
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• v.24 no.4
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• pp.371-379
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• 2008

The aim of this study was to evaluate the tightness of proximal tooth contact(TPTC) using a novel device at rest state on implant prostheses. Ten healthy young adults with class I normal occlusion consented to participate in the study and twenty patients were restored with a total 20 single-implant crowns in the left maxillary and mandibular second molars for 10 single-implant crowns, respectively. Test area were divided by 4 groups. UM describes the contact between the upper natural left first molar and natural second molar; LM the contact between the lower natural left first molar and natural second molar; IUM the contact between the upper natural left first molar and implant second molar and ILM the contact between the lower natural left first molar and implant second molar. The TPTC was measured at rest state in each area. The mean TPTC of the UM, LM, IUM and ILM was 1.48(${\pm}0.44$) N, 1.78(${\pm}0.40$) N, 1.14(${\pm}0.37$) N and 1.30(${\pm}0.32$) N respectively. These results indicate that the TPTC was less between natural tooth and implant prosthesis than between natural teeth.