• Journal of Life Science
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• v.33 no.9
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• pp.746-753
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• 2023

Viral infectious diseases have been regarded as one of the greatest threats to global public health. The recent coronavirus disease 2019 (COVID-19) pandemic caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a stark reminder of the threat posed by emerging viral infections. Developing and producing appropriate and efficient vaccines and therapeutics are the only options to combat this pandemic. The COVID-19 pandemic has highlighted the need for novel vaccine platforms to control and prevent emerging viral diseases. Conventional vaccine platforms, including live-attenuated vaccine and inactivated vaccines, pose limitations in the speed of vaccine development, manufacturing capacity, and broad protection for emergency use. Interestingly, vaccination with the SARS-CoV-2 vaccine candidate based on the mRNA-lipid nanoparticle (LNP) platform protected against COVID-19, confirming that the nucleoside-modified candidate is a safe and effective alternative to conventional vaccines. Moreover, the prophylactic strategies against the COVID-19 pandemic have been mRNA nucleic acid-based vaccines and nanoparticle-based platforms, which are effective against SARS-CoV-2 and its variants. Overall, the novel vaccine platform has presented advantages compared with the traditional vaccine platform in the COVID-19 pandemic. This review explores the recent advancements in vaccine technologies and platforms, focusing on mRNA vaccines, digital vaccines, and nanoparticles while considering their advantages and possible drawbacks.

• Journal of the Korea Society for Simulation
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• v.32 no.3
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• pp.55-66
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• 2023

In recent years, naval vessels have been developed to fulfill a variety of missions by being equipped with various cutting-edge equipment and ICT technologies. One of the main missions of Korean naval vessels is anti-ballistic missile warfare to defend key units and areas against the growing threat of ballistic missiles. Because the process of detection and interception is too complex and the cost of failure is much high, a lot of preparation is required to effectively conduct anti-ballistic missile warfare. This paper describes the development of a simulation model of anti-ballistic missile warfare with combat systems and equipment to be installed on future naval vessels. In particular, the DEVS formalism providing a modular and hierarchical modeling manner was applied to the simulation model, which can be utilized to efficiently represent various anti-ballistic missile warfare situations. In the simulation results presented, experiments were conducted to analyze the effectiveness of the model for effective detection resource management in anti-ballistic missile warfare. This study is expected to be utilized as a variety of analysis tools necessary to determine the optimal deployment and configuration of combat resources and operational tactics required for effective anti-ballistic missile warfare of ships in the future.

• Journal of the Korea Society for Simulation
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• v.18 no.4
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• pp.39-47
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• 2009

Recently, the threat of DDoS attacks is increasing and many companies are planned to deploy the DDoS defense solutions in their networks. The DDoS attack usually transmits heavy traffic data to networks or servers and they cannot handle the normal service requests because of running out of resources. Since it is very hard to prevent the DDoS attack beforehand, the strategic plan is very important. In this work, we have conducted modeling and simulation of the DDoS attack by changing the number of servers and estimated the duration that services are available. In this work, the modeling and simulation is conducted using OPNET Modeler. The simulation result can be used as a parameter of trade-off analysis of DDoS defense cost and the service's value. In addition, we have presented a way of estimating the cost effectiveness in deployment of the DDoS defense system.

• Research in Plant Disease
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• v.29 no.1
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• pp.52-59
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• 2023

Cucurbit chlorotic yellows virus (CCYV) is a plant virus that causes damage to cucurbit crops such as watermelon and cucumber, and is transmitted by an insect vector known as the whitefly. Since CCYV was first detected on cucumber in Chungbuk in 2018, it has been reported in other areas including Gyeongsang in Korea. In 2020, we performed field surveys of yellowing diseases in the greenhouses growing melon and watermelon in Chungbuk (Jincheon and Eumseong). Reverse transcription-polymerase chain reaction analysis of 79 collected samples including melon, watermelon, and weeds resulted in detection of CCYV in 4 samples: Three samples were singly infected with CCYV and one samples was mixed infected with CCYV, Cucurbit aphid borne yellows virus, and Watermelon mosaic virus. The complete genome sequences of the four collected CCYV melon isolates (ES 1-ES 4) were determined and genetically compared with those of previously reported CCYV isolates retrieved from GenBank. Phylogenetic analyses of RNA 1 and 2 sequences revealed that four ES isolates were clustered in one group and closely related to the CCYV isolates from China. The analysis also revealed very low genetic diversity among the CCYV ES isolates. In general, CCYV isolates showed little genetic diversity, regardless of host or geographic origins. CCYV has the potential to pose a serious threat to melon, watermelon, and cucumber production in Korea. Further studies are needed to examine the pathogenicity and transmissibility of CCYV in weeds and other cucurbits including watermelon.

• Journal of the Korea Institute of Information Security & Cryptology
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• v.33 no.2
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• pp.305-318
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• 2023

The complexity of software products led many manufacturers to stitch open-source software for composing a product. Using open-source help reduce the development cost, but the difference in the different development life cycles makes it difficult to keep the product up-to-date. For this reason, even the patches for known vulnerabilities are not adopted quickly enough, leaving the entire product under threat. Existing studies propose to use binary differentiation techniques to determine if a product is left vulnerable against a particular vulnerability. Despite their effectiveness in finding real-world vulnerabilities, they often fail to locate the evidence of a vulnerability if it is a small function that usually is inlined at compile time. This work presents our tool FunRank which is designed to identify the short functions. Our experiments using synthesized and real-world software products show that FunRank can identify the short, inlined functions that suggest that the program is left vulnerable to a particular vulnerability.

• Journal of Navigation and Port Research
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• v.47 no.1
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• pp.18-24
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• 2023

After the Great East Japan Earthquake, many reports and books that compiled testimonies of adult victims were published. Thus, refugee situations are well known, but information on the refugee situations of Japanese students is not. This is because what actions the students took and how they sought refuge from an earthquake or tsunami have not been fully recognized. The purpose of this study was to examine and analyze students' refuge behavior in the Great East Japan Earthquake and to predict the refuge behavior of students affected by future disasters. The results of the study showed that students passively acquired information about earthquakes and tsunamis and that their refuge behavior was highly dependent on adults. Immediately after an earthquake, people tended to protect themselves and stay in place until the shaking stopped. However, they tended to move to another place after the shaking occurred frequently. Students living on ria coastlines were likely to move to high places to escape the threat of earthquakes and tsunamis, whereas students living in plain regions were likely to move vertically to tall buildings, such as schools. As for the mode of movement to refugee shelters, the students arrived at the final refugee shelters in one move, and it is assumed that the refugee shelters should be decided in advance and the students should move there.

• Korean Journal of Environmental Biology
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• v.41 no.1
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• pp.31-40
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• 2023

In 2022, the Korean Ministry of Environment designated Parthenium hysterophorus as an ecosystem-disturbing plant. The purpose of this study was to present a management plan for P. hysterophorus considering its distribution, morphological, physiological, and ecological characteristics, and to introduce various control techniques. P. hysterophorus is native to Central America and occurs in about 45 countries worldwide. However, in Korea, it only grows in some areas of Tongyeong and Changwon, Gyeongsangnam Province. P. hysterophorus is an annual plant and spreads by seeds, moves between countries in the process of importing and/or exporting agricultural seeds, and spreads by agricultural machinery and vehicles after introduction. P. hysterophorus releases parthenin, an allelochemical that suppresses the occurrence of the surrounding vegetation, from its stems and roots. In addition, P. hysterophorus causes damage to humans and livestock through various allergens. P. hysterophorus can be controlled by physical methods, such as cutting its stems or pulling roots, and by treatment with non-selective herbicides, such as glyphosate. Many biological control research studies have been conducted and, unfortunately, there is no a practical solution so far.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.50 no.4
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• pp.287-295
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• 2022

As low altitude long-range artillery threat has been strengthened, the development of anti-artillery interception system to protect assets against its attacks will be kicked off. We view the defense of long-range artillery attacks as a typical dynamic weapon target assignment (DWTA) problem. DWTA is a sequential decision process in which decision making under future uncertain attacks affects the subsequent decision processes and its results. These are typical characteristics of Markov decision process (MDP) model. We formulate the problem as a MDP model to examine the assignment policy for the defender. The proximity of the capital of South Korea to North Korea border limits the computation time for its solution to a few second. Within the allowed time interval, it is impossible to compute the exact optimal solution. We apply approximate dynamic programming (ADP) approach to check if ADP approach solve the MDP model within processing time limit. We employ Shoot-Shoot-Look policy as a baseline strategy and compare it with ADP approach for three scenarios. Simulation results show that ADP approach provide better solution than the baseline strategy.

• Asia-pacific Journal of Multimedia Services Convergent with Art, Humanities, and Sociology
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• v.6 no.6
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• pp.229-240
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• 2016

Academic resilience of individual competencies that have overcome fatal or chronic adversity seen as a excessive threat in academic scene is the psychological ability to overcome stress. This study is a survey research carried try to identify the factors that affect the academic resilience of nursing students. Interpersonal communication competence and happiness to target the nursing students of the total 554 people to investigate the effect on the academic resilience, were analyzed using the SPSS version 21.0. The main results are as follows. (1) academic resilience could vary depending on the grade, living arrangements, Interpersonal relationship, personality and academic performance. (2) academic resilience had a positive correlation with interpersonal communication competence(r=.46, p<.001) and happiness(r=.35, p<.001). (3) factors that had significant impact on academic resilience of nursing students were grade(p=.002), living arrangements(p=.001), academic performance(p<.001), interpersonal communication competence(p<.001) and happiness(p<.001) and explanatory power was 36.9%. Through this study, interpersonal communication competence and happiness were identified as having the positive effect on academic resilience. As a follow-up, in order to improve academic resilience, a study to develop programs that would promote interpersonal communication competence and happiness are suggested.

• Korea Science and Art Forum
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• v.30
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• pp.251-261
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• 2017

Metal is a material that has exerted a lot of influence on the development of human cultures, and has closely connected with our life from the past to the present. Types of metal we have used from the prehistoric times are varied, and iron relics take the largest percentage of metal relics excavated in our country. The biggest threat to the existence of iron relics ranging from excavated relics to the ones that are transmitted is the process of corrosion, and physical removal has been used the most for removing corroded oxides. For details for removal of corrosion oxides, this thesis aimed to research on the chemical corrosion oxides remover that protects parent material of iron relics but treats corrosion oxides only. For safe and effective removal of corrosion oxides of iron relics, this study was conducted aiming at finding the possibility of and optimized composition for removal of iron relics corrosion oxides by manufacturing new acid, alkaline and neutral oxides removers and changing their composition variously, exploring the possibility by applying the agents to modern relics. The results of this study are as follows: First, the acid solution removed only some part of corrosive substance oxidized on the surface of metal specimen. Second, the application of each of alkaline and neutral solution resulted in remaining black-colored corrosive substance, but it was removed when the quantity of the solution and the duration of application are increased. Third, All the three solutions did not cause any damage to parent material in the course of application, and showed the result that they are capable of removing unstable oxide layer while protecting parent material and stable corrosive layer as the solutions would be able to deal with situation by a relic only through the control of concentration of solution and duration of application.