• Title/Summary/Keyword: TF

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Complex Modulus of Alumina Green Tapes Measured by Micro Fourier Rheometer (Micro Fourier Rheometer에 의한 알루미나 그린 테이프의 Complex Modulus 측정)

  • ;;;;Michael V. Swain;Bruno Pfister
    • Journal of the Korean Ceramic Society
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    • v.36 no.2
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    • pp.122-129
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    • 1999
  • Alumina tapes, having various weight ratios of alumina powder/(alumina+binder+plasticizer), X, and binder / (binder+plsticizer), Y, were prepared and their complex modulus was measured using Micro Fourier Rheometer. As the X and Y ratios increased, Transfer function(TF) magnitude and Transfer function (TF) phase increased and decreased, respectively, indicating that the elastic modulus of the tapes depends on the weight ratios. The temperature dependence of the viscosity of the tapes was visualized by the decreased TF magnitude and the increased TF phase. The Y ratio dependence of the complex modulus related to the glass transition temperature of the tapes and the moduls change by the Y ratio was higher than that by the X ratio within the comperature of the tapes and the modulus changes by the Y ratio was higher than that by the X ratio within the composition range, investigated in the present study. The measurement of the complex modulus of the alumina tapes suggested that the TF phase should be higher that 17$^{\circ}$for the tapes to be utilized for 3-dimensional shaping.

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Tissue factor expression is associated with recurrence in patients with non-metastatic colorectal cancer

  • Jung, Hee Jae;Kim, Hye Jin;Kaneko, Kensuke;Kazama, Yoshihiro;Kawai, Kazushige;Ishihara, Soichiro;Choi, Gyu-Seog
    • Korean Journal of Clinical Oncology
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    • v.14 no.2
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    • pp.128-134
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    • 2018
  • Purpose: Previous studies have addressed the role of the hypercoagulable state in the pathogenesis of cancer progression and metastasis. In this study, we investigated the association between coagulation factors, including tissue factor (TF) expression, platelet count, and fibrinogen level, and disease recurrence in patients with non-metastatic colorectal cancer. Methods: Patients who underwent curative resection for stage II or III colorectal cancer between 2000 and 2007 were included in this study. Data from a prospectively maintained database were retrospectively reviewed. TF expression was determined by immunohistochemistry using an anti-TF monoclonal antibody. The Kaplan-Meier method was used to estimate 5-year disease-free survival. Results: TF was highly expressed in 257 of 297 patients (86.5%). TF expression was not significantly associated with the platelet counts (P=0.180) or fibrinogen level (P=0.281). The 5-year disease-free survival rate was lower in patients with high TF expression than in patients with low TF expression (72.3% vs. 83.9%, P=0.074). In Cox hazard analysis, high TF expression was an independent risk factor for tumor recurrence (hazard ratio [HR] 2.446; 95% confidence interval [CI], 1.054-5.674; P=0.037). Undifferentiated histologic type (HR, 2.911; 95% CI, 1.308-6.481; P=0.009), venous invasion (HR, 2.784; 95% CI, 1.431-5.417; P=0.003), and lymph node metastasis (HR, 2.497; 95% CI, 1.499-4.158; P<0.001), were also significantly associated with disease recurrence. Conclusion: TF expression is associated with a recurrence in patients with non-metastatic colorectal cancer. However, further studies are required to clarify the underlying mechanisms relating TF expression with oncologic outcomes and its potential role as a therapeutic target.

Quality Characteristics and Antioxidant Activities of Cookies containing Teff (Eragrostis tef) Flour (Teff (Eragrostis tef) 분말을 첨가한 Gluten-free 쿠키의 품질 특성 및 항산화 활성 비교)

  • Joung, Ki Youeng;Song, Ka-Young;O, Hyeonbin;Zhang, Yangyang;Shin, So Yeon;Kim, Young-Soon
    • The Korean Journal of Food And Nutrition
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    • v.30 no.3
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    • pp.501-509
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    • 2017
  • This study investigated the quality characteristics and antioxidant activities of gluten-free cookies containing teff flour. By substituting 0% (control), 25% (TF25), 50% (TF50), 75% (TF75), and 100% (TF100) of wheat flour with teff flour, five samples were produced. Baking loss rate was the highest in TF25 at 13.76% and the lowest in TF75 at 4.03%. Spread factor was significantly higher in cookies made with teff flour (83.00~85.00) than in the control (81.33) (p<0.05). There was no significant difference in density among the samples at 1.17~1.25 g/mL (p<0.05); however, pH significantly decreased at 6.42~6.04 (p<0.05). While the L-value and b-value significantly decreased with the amount of teff flour, the a-value significantly increased (p<0.05). The ${\Delta}E$ value was the highest in the control at 31.31 and the lowest in TF100 at 58.69. Hardness was the highest in the control at 42.04 N than in cookies containing teff flour. The content of polyphenols was the highest in TF100 at $3.37{\mu}g\;GAE/mg$ and the lowest in the control at $1.32{\mu}g\;GAE/mg$. The content of flavonoids was the highest in TF100 at $3.66{\mu}g\;QE/mg$ and the lowest in controls at $0.45{\mu}g\;QE/mg$. The value of DPPH $IC_{50}$ was the highest in the control at $3,723.00{\mu}g/mL$ and the lowest in TF 100 at $405.27{\mu}g/mL$. The value of ABTS $IC_{50}$ was the highest in the control at $1,822.32{\mu}g/mL$ and the lowest in TF100 at $529.30{\mu}g/mL$. In sensory evaluation, while control, TF75, and TF100 had a higher score in appearance at 5.52~5.60, all samples had no significant differences in flavor, sweetness, savory taste, chewiness, and overall acceptability (p<0.05). These results showed that the gluten-free cookies containing teff flour can improve the quality characteristics and antioxidant activities of a cookie. We concluded that gluten-free cookies containing 100% teff flour are desirable.

Comparison of $^{99m}Tc$-tetrofosmin and $^{99m}Tc$-sestamibi Myocardial Perfusion SPECT in Detecting Coronary Artery Fisease (부하-휴식 1일 영상법을 이용한 심근관류 SPECT에서 $^{99m}Tc$-tetrofosmin과 $^{99m}Tc$-MIBI의 관동맥질환 진단율 비교)

  • Min, Jung-Jun;Bom, Hee-Seung;Song, Ho-Cheon;Jeoung, Hwan-Jeoung;Kim, Ji-Yeul
    • The Korean Journal of Nuclear Medicine
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    • v.32 no.2
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    • pp.137-142
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    • 1998
  • Purpose: $^{99m}Tc$-tetrofosmin(TF) is a recently proposed myocardial imaging agent which has similar biokinetic characteristics to $^{99m}Tc$-sestamibi(MIBI). The aim of this study was to compare TF and MIBI myocardial perfusion SPECTs in detecting coronary artery disease. Materials and Methods: One hundred and sixty patients(101 males, 59 females, mean age $57{\pm}9yr$) who had undergone both myocardial perfusion SPECT(M-SPECT) and coronary angiography within 1 month were studied. M-SPECT was performed using TF in 115 patients and MIBI in 45 patients. Stress-rest one day protocol was used in all patients. A coronary stenosis was considered significant when the luminal diameter ${\geq}$50% was compromised. The chi square test was used to compare differences in sensitivity and specificity between the two groups. Results: There was no difference in age and diseased coronary artery branches between the two groups. There were more male patients in TF group: Male-to-female ratios of TF and MIBI groups were 78:37 and 23:22, respectively(p<0.05). The overall sensitivity of TF study was 92% and specificity 36%. The overall sensitivity and specificity of MIBI study were 93% and 30%, respectively. There was no difference between TF and MIBI groups in identifying individual diseased coronary artery branches. Conclusion: One day stress-rest myocardial SPECT using either TF or MIBI was comparable and was a very sensitive test in detecting coronary artery disease.

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Study on the Quality Characteristics and Retarding Retrogradation of Pound Cakes containing Teff (Eragrostis tef) Flour (테프(Eragrostis tef) 분말을 첨가한 파운드케이크의 품질 특성 및 노화 억제 분석)

  • Joung, Ki Youeng;Song, Ka-Young;O, Hyeonbin;Zhang, Yangyang;Shin, So Yeon;Kim, Young-Soon
    • Journal of the East Asian Society of Dietary Life
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    • v.27 no.1
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    • pp.41-49
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    • 2017
  • This study investigated the effects of teff flour on the properties of pound cakes. Five types of pound cakes were made by addition of 0% (Control), 5% (TF5), 10% (TF10), 15% (TF15), and 20% (TF20) of teff flour based on wheat flour. Specific gravity of pound cake batter showed no significant differences among samples as 0.54 (p<0.05). Baking loss was the highest in the control at 5.92% and the lowest in TF20 at 5.27%. Batter yield was the highest in TF20 at 94.73% and the lowest in control at 94.08%. Moisture content was the highest in TF20 at 23.68% and the lowest in control at 21.32%. pH showed no significant differences among samples at 7.61~7.65 (p<0.05). a-values of crumb significantly increased while L-values and b-values significantly decreased with added teff flour amounts. (p<0.05). ${\Delta}E$ values significantly increased with teff flour at 34.32~49.24 (p<0.05). Hardness was lowest in TF20 at $180.60g/cm^2$. Springiness was the lowest in TF20 at 85.37%. Cohesiveness showed no significant differences among samples (p<0.05). Chewiness was the lowest in TF20 at 172.17 g. Hardness more rapidly increased in control at $273.13{\sim}26,123.33g/cm^2$ than that of pound cakes with teff flour. Avrami exponent (n) was the highest in the control at 3.5987 and the lowest in TF20 at 1.2144. In sensory evaluation, flavor of TF20 was higher than that of the control at 4.43. Overall acceptability had a higher score in TF20 than in the control. It is considered that addition of 20% teff flour can improve the quality characteristics and retard retrogradation of pound cake.

Formulation of New Hyperbolic Time-shift Covariant Time-frequency Symbols and Its Applications

  • Iem, Byeong-Gwan
    • The Journal of the Acoustical Society of Korea
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    • v.22 no.1E
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    • pp.26-32
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    • 2003
  • We propose new time-frequency (TF) tools for analyzing linear time-varying (LTV) systems and nonstationary random processes showing hyperbolic TF structure. Obtained through hyperbolic warping the narrowband Weyl symbol (WS) and spreading function (SF) in frequency, the new TF tools are useful for analyzing LTV systems and random processes characterized by hyperbolic time shifts. This new TF symbol, called the hyperbolic WS, satisfies the hyperbolic time-shift covariance and scale covariance properties, and is useful in wideband signal analysis. Using the new, hyperbolic time-shift covariant WS and 2-D TF kernels, we provide a formulation for the hyperbolic time-shift covariant TF symbols, which are 2-D smoothed versions of the hyperbolic WS. We also propose a new interpretation of linear signal transformations as weighted superposition of hyperbolic time shifted and scale changed versions of the signal. Application examples in signal analysis and detection demonstrate the advantages of our new results.

An Exploratory Study on Survey Data Categorization using DDI metadata (메타데이터를 활용한 조사자료의 문서범주화에 관한 연구)

  • Park, Ja-Hyun;Song, Min
    • Proceedings of the Korean Society for Information Management Conference
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    • 2012.08a
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    • pp.73-76
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    • 2012
  • 본 연구는 DDI 메타데이터를 활용하여 귀납적 학습모델(supervised learning model)의 문서범주화 실험을 수행함으로써 조사자료의 체계적이고 효율적인 분류작업을 설계하는데 그 목적이 있다. 구체적으로 조사자료의 DDI 메타데이터를 대상으로 단순 TF 가중치, TF-IDF 가중치, Okapi TF 가중치에 따른 나이브 베이즈(Naive Bayes), kNN(k nearest neighbor), 결정트리(Decision tree) 분류기의 성능비교 실험을 하였다. 그 결과, 나이브 베이즈가 가장 좋은 성능을 보였으며, 단순 TF 가중치와 TF-IDF 가중치는 나이브 베이즈, kNN, 결정트리 분류기에서 동일한 성능을 보였으나, Okapi TF 가중치의 경우 나이브 베이즈에서 가장 좋은 성능을 보였다.

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Cloning and Characterization of the Putative Transferrin Receptor cDNA from the Olive Flounder (Paralichthys olivaceus)

  • Won Kyoung-Mi;Park Soo-Il
    • Fisheries and Aquatic Sciences
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    • v.6 no.2
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    • pp.101-104
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    • 2003
  • A cDNA clone for the olive flounder (Paralichthys olivaceus) transferrin receptor (fTfR) was isolated from a leukocytes cDNA library. The fTfR gene consisted of 2,319 bp encoding 773 amino acid residues. The amino acid sequence alignment of the fTfR showed that their size and hydrophobic profile are similar. In addition, the Tyr-Thr-Arg-Phe (YTRF) motif that is the recognition signal for high-efficiency endocytosis, is conserved very well. This motif is important for functional properties of TfR. The deduced amino acid sequence had $42.4-42.9\%$ identities with the previously reported TfRs of vertebrates. The fTfR was expressed in the blood, kidney, spleen, and liver of healthy olive flounder by the Northern blot hybridization.

Changes in the Level of Transferrin Receptor during the Differentiation of Chick Brain Neuroblasts (계배 신경아세포의 분화에 따른 Transferrin 수용체의 변화)

  • 이창호;전영주
    • The Korean Journal of Zoology
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    • v.35 no.2
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    • pp.144-148
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    • 1992
  • Insulin and transfenin (Tf) were found to be essential for suwival and differentiation of brain neuroblasts obtained from chick embryo. This requirement, however, is Changed from insulin to Tf upon neuronal development of the embryo, and this phenomenon is due to the changes in the levels of corresponding receptors. Using cultured neuroblasts, the level of Tf receptor is also found to increase Lvhile that of insulin receptor falls dramatically during the course of the cell differentiation. These results suggest that the development-specific changes in the levels of insulin and Tf receptors in embryo can be reproduced in the culture system during the differentiation period. Because the culture system used was a defined medium and contained no other macromolecules than insulin and Tf, it appears possible that insulin and Tf may act as signalling molecules in the control of neuronal development.

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Antioxidant Activity of Theaflavin and Thearubigin Separated from Korean Microbially Fermented Tea

  • Shon, Mi-Yae;Park, Seok-Kyu;Nam, Sang-Hae
    • Preventive Nutrition and Food Science
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    • v.12 no.1
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    • pp.7-10
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    • 2007
  • Theaflavins (TF) and thearubigins (TR) were separated from Korean microbially fermented tea leaves. Contents of TF (74.4 $\mu$M/g) and TR (37.2%) were higher than reported for black tea fermented by oxidase. Antioxidant activities of TF, TR and EGCG were analyzed and protective effects of COS-7 cells against copper and cadmium-induced toxicity were investigated. TF and TR exhibited good inhibition rates of about 85$\sim$90% for antioxidant and scavenging activities of free radicals and protected COS-7 cells against apoptosis or damage caused by stress, such as cadmium and copper-oxidative injury, free radicals etc. These results indicate that TF, TR and EGCG have antioxidant and scavenging activities against free radicals and protect COS-7 cells from Cu, Cd induced injury.