• BMB Reports
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• v.40 no.3
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• pp.358-367
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• 2007

A novel mannose-binding tuber lectin with in vitro antiproliferative activity towards human cancer cell lines and antiviral activity against HSV-II was isolated from fresh tubers of a traditional Chinese medicinal herb, Typhonium divaricatum (L.) Decne by a combined procedure involving extraction, ammonium sulfate precipitation, ion exchange chromatography on DEAE-SEPHAROSE, CM-SEPHAROSE and gel-filtration on sephacryl S-200. The apparent molecular mass of the purified Typhonium divaricatum lectin (TDL) was 48 kDa. TDL exhibits hemagglutinating activity toward rabbit erythrocytes at 0.95 $\mu$g/ml, and its activity could be strongly inhibited by mannan, ovomucoid, asialofetuin and thyroglobulin. TDL showed antiproliferative activity towards some well established human cancer cell lines, e.g. Pro-01 (56.7 $\pm$ 6.8), Bre-04 (41.5 $\pm$ 4.8), and Lu-04 (11.4 $\pm$ 0.3). The anti-HSV-II activity of TDL was elucidated by testing its HSV-II infection inhibitory activity in Vero cells with $TC_50$ and $EC_50$ of 5.176 mg/ml and 3.054 $\mu$g/ml respectively. The full-length cDNA sequence of TDL was 1145 bp and contained an 813-bp open reading frame (ORF) encoding a 271 amino acid precursor of 29-kDa. Homology analysis showed that TDL had high homology with many other mannose-binding lectins. Secondary and three-dimensional structures analyses showed that TDL is heterotetramer and similar with lectins from mannose-binding lectin superfamily, especially those from family Araceae.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.19 no.8
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• pp.1421-1432
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• 1994

The optimum design and performance of noncoherent TDL considering the effect of distortions due to the IF bandpasss filters are described. NRZ data and ideal filter is presumed in the simulation. The optimum filter bandwidth is calculated in the sense of minimizing the loop's squaring loss, which is equivalent to minimizing the loop's tracking jitter for a given data rate and data signal-to-noise ratio. As a result, the optimum filter bandwidth depends on the signal-to-noise ratio, and is obtained in the range of about 1-2 times of the data rate.

• The Journal of the Korea institute of electronic communication sciences
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• v.14 no.6
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• pp.1069-1076
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• 2019

With the development of information and communication technology, the military's battle environment is changing greatly to network centric warfare in where weapon system is connected in a network and carries out mission by exchanging the real-time data. The core of the network centric warfare is Tactical Data Link(TDL) system, and subscribers of TDL exchange tactical information in real time through wireline, wireless and satellite network to share the battlefield situation. The amount of data sent and received through TDL inevitably increase as military's weapon systems equipped with TDL systems increase over time and the performance of communications equipment improves. This study proposes ways to improve the transmission speed and processing capacity of the TDL system by improving the Data Link Processor.

• 한국연소학회:학술대회논문집
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• 2006.10a
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• pp.160-167
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• 2006

In this project, we studied more accurate and reliable sensing method for oxygen in reheating furnace, made the empirical model for NOx concentration based on oxygen and evaluate the stability of the Tuneable Diode Laser (Absorption) Spectroscopy(TDL(A)S). The tested oxygen monitoring system is installed at work-field reheating furnace on hot roll at POSCO and compared with the Zr sensor system which shows too sensitive because it measures oxygen concentration on a spot unlike TDLS sensor which is successfully applied at 13m-width reheating furnace to measures the line average along the Optical Path Line(OPL).

• Journal of the Korea Institute of Military Science and Technology
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• v.13 no.3
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• pp.388-396
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• 2010

Generally, flight information is transmitted by voice signal over legacy UHF radio in ground to air communication system. In this paper, we have implemented the transceiver of TDL(tactical data link) which transmits tactical information, such as flight information, using digital signal. For transmitting digital information over radio path, we have designed data modem that is processing CPFSK modulation, and TDMA(Time Division Multiple Access) network for Synchronization among multi user(platform). By simulating aeronautical propagation modeling with the environment of Korea terrain, it is predicted the maximum performance of communication range of the transceiver. As result of the transceiver's aviational boarding test, it is proved that the transceiver of TDL over legacy UHF radio transmits and receives the tactical information in TDMA network within communication range of 160km.

• The Journal of the Acoustical Society of Korea
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• v.18 no.5
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• pp.3-11
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• 1999

The conventional stereophonic acoustic echo cancellers need two adaptive filters to estimate one channel echo signal. Since the two channel signals are strongly correlated, the ESR of the input signals is considerably increased whatever the input signals may be. This causes the slow convergence of the adaptive filter for echo cancellation. To speed up the convergence, the AP algorithm is frequently used for the stereophonic acoustic echo canceller although there isn't a fast version for 2-channel case. The AP algorithm can be approximated with the Gram-Schmidt orthogonalization and a TDL structure. We propose a two channel algorithm for stereophonic acoustic echo canceller with the approximated AP algorithm.

• Toxicological Research
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• v.19 no.2
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• pp.133-139
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• 2003

Allergic contact dermatitis may be caused by a wide variety of chemicals. A murine local lymph node assay (LLNA) has been developed as an alternative to guinea pig models for assessing the contact sensitization potential of chemical. However, there is a need to develop a nonradioisotopic endpoint for the LLNA, because of the radioisotopic method's requiring the use of special facilities. In this study, we investigated the development of a nonradioisotopic endpoint for LLNA using ELISA (enzyme-linked immunosorbent assay). Female Balb/c mice were treated by the topical application on the dorsum of both ears with four different strong sensitizers, 2,4-dinitrochlorobenzene (DNCB), oxazolone (OXZ), toluene diisocyanate (TDI), and trimellitic anhydride (TMA), and a strong irritant, sodium lauryl sulfate (SLS), once daily for three consecutive days. The proliferation of cells in the auricular Iymph node was analyzed by means of the labelling index (Ll) of bromodeoxyuridine (BrdU) incorporation into cells. The weights of the Iymph nodes in the mice treated with allergens, DNCB, OXZ, TDl and TMA were increased compared to the vehicle control. The stimulation index (Sl) of mice treated with DNCB, OXZ, TDl, and TMA was over three-fold increase compared to the vehicle control. However, the S1 of mice exposed to SLS was not significantly increased compared to the vehicle control, while the lymph node weight of SLS was significantly increased. These results suggest that the LLNA modified endpoint using ELISA based on BrdU incorporation could provide a useful method of screening for irritants and allergens.

• Journal of the Korean Institute of Telematics and Electronics S
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• v.35S no.10
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• pp.166-174
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• 1998

Neural networks, having highly nonlinear dynamics by virtue of the distributed nonlinearities and the learing ability, have the potential for the adaptive prediction of nonstationary signals. This paper describes the nonlinear prediction of these signals in two ways; using a nonlinear module and the cascade combination of nonlinear and linear modules. Fully-connected recurrent neural networks (RNNs) and a conventional tapped-delay-line (TDL) filter are used as the nonlinear and linear modules respectively. The dynamic behavior of the proposed predictors is demonstrated for chaotic time series adn speech signals. For the relative comparison of prediction performance, the proposed predictors are compared with a conventional ARMA linear prediction model. Experimental results show that the neural networks based adaptive predictor ourperforms the traditional linear scheme significantly. We also find that the cascade combination predictor is well suitable for the prediction of the time series which contain large variations of signal amplitude.

• The Journal of the Korea institute of electronic communication sciences
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• v.16 no.6
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• pp.1045-1052
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• 2021

Modern Warfare is transforming into a Network Centric Warfare(NCW) where surveillance systems, command control systems and strike systems are interconnected with advanced IT technologies to share battlefield situations. The South Korean military is using the various tactical data links(TDL) such as Link-K, Link-16, Link-11 and KVMF depending on each military's battlefield situation. Joint Tactical Data Link System(JTDLS) is a system thar shares tactical information in near-real time between army/navy/air joint forces and additionally establishes Link-22 in Link-K, Link-16 and KVMF. In this paper, we propose the Link-22 system structure, Link-22 message analysis and the interface structure between the tactical data link processor and Link-22 to apply Link-22 to the JTDLS.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.62 no.3
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• pp.380-386
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• 2013

This paper represents an adaptive beamforming technique to suppress interference or jamming signals in wideband. In order to maintain low side lobe level(SLL) at an antenna element level, Taylor-weighting was used. Also, to make a nulling beam pattern toward jammer's directions in wideband, we used the modified Loaded Sample Matrix Inversion(LSMI) algorithm and Tapped Delay Line(TDL). To verify the proposed algorithm, we applied it to a rectangular array antenna. Finally, the results show beam pattern with low SLL and jammers suppression.