• Journal of Life Science
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• v.27 no.11
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• pp.1357-1368
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• 2017

The purpose of this study was to investigate the anti-obesity and anti-inflammation effect of the cheonggukjang (a soybean paste fermented for only a few days) in diet induced obesity mice. Weight gain was significantly decreased in the mice fed cheonggukjang compared High Fat Diets (HFD). The HFD plus cheonggukjang (CGJ) were also effective in improving the lipid metabolism. The levels of plasma triglyceride, cholesterol, ALT, AST, leptin, glucose, and insulin were significantly lower in CGJ than HFD group (p<0.05). The adiponectin level of CGJ group was significantly increased compared to the HFD group (p<0.05). In the CGJ group, the mRNA expression of adipogenic genes in the liver and adipose tissues, which are transcription factors crucial for adipogenesis, were significantly suppressed (p<0.05). The number of $CD11b^+F4/80^+$ T cells, $Gr-1^{int}CD11b^{high}$ cells, and $Gr-1^{int}CD11b^{high}$ cells were significantly higher in HFD group than CGJ group (p<0.05). The size of adipocyte was significantly reduced in CGJ group compared to HFD group. In addition, the contents of liver lipid droplets were significantly downregulated in the CGJ mice than HFD mice (p<0.05). Collectively, these data suggest the novel function of cheonggukjang in modulating adipogenesis through an immune function-alteration involving downregulation of adipogenic transcription factors and macrophage activation.

• Herbal Formula Science
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• v.5 no.1
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• pp.169-178
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• 1997

To investigate effect of water extract of Asparagi Tuber(天門冬) on human cancer cell-lines and immunocytes, this research estimated proliferation of A431 cell line, KHOS-NP cell line, mouse thymocytes and mouse splenocytes, Nitric Oxide(NO) from macrophage, apoptosis and subpopulation of the mouse thymocytes. The result were obtained as follows ; 1. Asparagi Tuber inhibited the proliferation of A431 cell line. 2. Asparagi Tuber inhibited the proliferation of KHOS-NP cell line. 3. Asparagi Tuber accelerated the proliferation of mouse thymocytes. 4. Asparagi Tuber inhibited the proliferation of mouse splenocytes. 5. Asparagi Tuber $100{\mu}g/m{\ell}$ inhibited the production of NO from macrophages in vitro, being compared NPS+IFN treated group. 6. Asparagi Tuber inhibited the production of NO from macrophages in vivo, being compared LPS+IFN treated group. 7. Asparagi Tuber accelerated the induction of apoptosis of the mouse thymocytes. 8. In subpopulation Asparagi Tuber increased $T_H$ of the mouse thymocytes, but decreased $T_C/T_S$ of the mouse thymocytes.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2009.05a
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• pp.3-3
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• 2009

In order to investigate the possibility of using mixed rare earth $(Nd_{1/3}Eu_{1/3}Gd_{1/3})Ba_2Cu_3O_{7-x}$ (NEG123) as the superconducting layer of the HTS coated conductor, the NEG123 thin film was deposited epitaxialy on LAO(100) single crystal and IBAD_YSZ metal templates by pulsed laser deposition. Systematic studies were carried out to investigate the influences of deposition parameters of PLD on the micro structure, texture and superconducting properties of NEG-123 coated conductor. Deposition at oxygen partial pressure of 600 mTorr was needed to routinely obtain high quality NEG123 films with $J_c$'s (77K) over 2 MA/$cm^2$ and Tc's over 90K (${\Delta}T{\sim}2\;K$). We verified from magnetization study that the NEG123 has an improved in-field Jc as the field increases at temperatures between 10 K and 77 K compared with Gd123. The $J_c$ (77K, self field) and the value of onset $T_c$ of NEG123 thin film on LAO substrate was $4.0MA/cm^2$ and 92K, respectively. This is the first report, to the best of our knowledge, of coated conductors with NEG123 film as the superconducting layer which have Ic and Jc over 40 A/cm-width and 1.6 MA/$cm^2$ at 77K, self field. This study shows the possibility of using NEG123 film as the superconducting layer of the HTS coated conductor which can be used in high magnetic field power electric devices.

• The Korea Journal of Herbology
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• v.27 no.5
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• pp.1-7
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• 2012

Objectives : This study was conducted to 9% compared with the previous experimental obesity-induced metabolic function in rats that it was a mixture of pear extract and herbal drugs(Lycii Fructus, Coicis Semen, Alimatis Rhizoma and Astragali Radix) on high fat diet-induce obesity rats. Methods : The animals were used in male rats. Control group fed high-fat diet only. Experimental groups were divided four, ExpI group was fed high-fat diet with a mixture pear extract and Lycii Fructus 9%, Exp II group was fed high-fat diet with a mixture pear extract and Coicis Semen 9%, Exp III group was fed high-fat diet with a mixture pear extract and Alimatis Rhizoma 9%, and Exp IV group was fed high-fat diet with a mixture pear extract and Astragali Radix 9% for 4 weeks. Results : The body weight gain increased in all groups, but attenuated gradually in the experimental groups compared to the control group. The food intakes were significantly lower in all Exp groups than the control group. The concentrations of serum total cholesterol (TC), LDL-cholesterol, and free fatty acid were significantly lower in Exp II than in the control group. Also the concentration of serum free fatty acid was significantly lower in the Exp IV group than in the control group. In inflammatory activities, the Exp II, IV group was significantly lower than the control group. Conclusion : The results indicated that Exp I group (administered a mixture of pear extract and Lycii Fructus) reduced fat accumulation, body weight and the highest elevated lipid metabolism, while the Exp II group (administered the mixture of pear extract and Coicis Semen) and Exp IV group (administered the mixture of pear extract and Astragali Radix) had the highest elevated immune activity.

• Journal of the East Asian Society of Dietary Life
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• v.15 no.4
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• pp.386-396
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• 2005

The effects of spirulina-added salad dressing on lipid profiles and antioxidant biomarkers such as total glutathionine, TBARS value, carbonyl value, GPx, GR, SOD and paraoxonase activity in plasma or liver of mice were evaluated Sixteen male ICR mice weighing 20$\pm$2 g were divided into two groups and fed low fat ($5\%$ fat) diet (low fat control: LFC) and low fat control plus dressing diet (LFD) for eight weeks. Body weight, tissue weights of liver, heart and kidney, and the distribution of body fat deposition were not significantly different between two groups. Also, the profile of TG, TC, LDL and HDL cholesterol were similar between two groups. The DNA damage was determined using the comet assay (single cell gel assay) with alkaline electrophoresis and quantified by measuring tail length (TL). Spirulina salad dressing consumption resulted in significant decrease in lymphocyte DNA damage expressed by TL (LFC: $28.8{\mu}m$, LFD: $20.3{\mu}m$). Additionally, salad dressing consumption for 8 wks decreased the lipid peroxidation assayed by TBARS to $12.6\%$ compared with the control. The levels of antioxidant vitamins such as $\beta$-carotene were significantly higher in plasma of LFD group than those in LFC group based on HPLC method This study shows that spirulina-added salad dressing exerts degenerative disease-protective effects on oxidative DNA damage and lipid peroxidation possibly via a free radical levels.

• Korean Journal of Food Science and Technology
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• v.37 no.1
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• pp.44-49
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• 2005

Physicochemical properties of hydroxypropylated rice starches were investigated. Swelling power of hydroxypropylated rice starch increased at relatively lower temperature than native rice starch. Solubility of hydroxypropylated rice starch was lower (1.9-13.4%) than that of native rice starch (2.2-13.8%), and increased with increasing amount of propylene oxide. Pasting temperature ($66.2-70.8^{\circ}C$) and peak viscosity (2,843-3,395cp) of hydroxypropylated rice starch were lower than those of native starch ($71.6^{\circ}C,\;3,976\;cp$) and decreased with increasing amount of propylene oxide, regardless of reaction time. DSC thermal transitions of hydroxypropylated rice starches shifted toward lower temperature. Amylopectin-melting enthalpy of hydroxypropylated rice starch decreased (11.8-9.8J/g) with increasing amount of propylene oxide and was lower than that of native starch (11.9 J/g). These results indicate hydroxypropylation lowered swelling power and gelatinization temperatures of rice starch, because internal bonds of rice starch molecules were sterically weaken by substituted hydroxypropyl groups.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.39 no.1
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• pp.34-41
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• 2002

In the conventional rake receiver structure for the IS-95 CDMA system, each finger has its own time-deskew buffer or FIFO that aligns the multipath signals to the same timing reference in order to combine symbols. This architecture is not a burden to the rake receiver design mainly because of the small number and size of the buffers. However, the number and size of the buffers are significantly increased in the cdma2000 system which adopts multiple carriers and the small spreading gain for a higher rate in data services. In order to decrease the number of buffers, we propose a new model of the time-deskew buffers, which combines the symbols as well as realigns them at the same time. Our architecture reduces the hardware complexity of the buffers by about more than 60% and 70% compared with the conventional one when we consider each rake receiver has three and four independent fingers, respectively. Moreover, the proposed algorithm is very useful not only to the cdma2000 rake receiver but also to the receiver with many fingers in order to increase the BER performance.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.45 no.4
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• pp.31-37
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• 2008

Conventional cooperative communications can attain gain of spatial diversity and path loss reduction because destination node independently received same signal from source node and relay node located between source node and destination node. However, these techniques bring about decreased spectral efficiency with relay node and increased complexity of receiver by using maximal ratio combining (MRC). This paper has proposed cooperative ARQ protocol that can improve the above problems and can get the better performance. This method can increase the spectral efficiency than conventional cooperative communication because if the received signal from source node is satisfied by the destination preferentially, the destination transmits ACK message to both relay node and source node and then recovers the received signal. In addition, if ARQ message indicates NACK relay node operates selective retransmission and we can increase reliability of system compared with that of general ARQ protocol in which source node retransmits data. In the proposed protocol, the selective retransmission and ARQ message are to be determined by comparing log-likelihood ratio (LLR) computation of received signal from source node with predetermined threshold values. Therefore, this protocol don't waste redundant bandwidth with CRC code and can reduce complexity of receiver without MRC. We verified spectral efficiency and BER performance for the proposed protocol through Monte-Carlo simulation over Rayleigh fading plus AWGN.

• The Proceeding of the Korean Institute of Electromagnetic Engineering and Science
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• v.5 no.4
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• pp.83-93
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• 1994

1886년 고트리브 다이믈러와 칼 벤즈가 가솔린 자동차를 개발한 이후 100여년이 지난 지금 자동차는 비약적으로 진보, 발전하여 현대 산업사회와 개인의 생활에 있어 산업운송수단과 이동수단으 로서 필요불가결하게 되어 밀접한 관계를 갖고 있다. 우리나라 자동차 공업의 역사는 자동차가 사회적, 경제적 효용에 따라 그 생산과 보유대수가 날이 갈수록 증가 일로에 있으며, 자동차의 생산대수는 전세 계에서 년간 약 50,606천대('94년)로서 중요한 국가 기간 산업으로 자리하고 있다. 한편 전기, 전자공업의 발전에 따른 자동차의 Car Electronics가 많이 채용되게 됨에 따라 현재의 자 동차에는 대부분이 전자제어 System으로 구성되어 있다. 최근에는 Micro Processor를 이용한 전자부품이 많이 사용되어 전자파에 대한 문제가 다양하게 발생 하고 있다. 예를 들면 미국 캘리포니아주에서 전자점화제어장치와 연료분사 장치를 설치한 구미의 자동 차가 주행중 28MHz, 28W의 아마추어 무선을 탑제한 자동차가 통과할 때 엔진이 고르지 못한 보고가 있 었고, 화학섬유로된 옷을 착용한 전자부품이 다른 부품에 영향을 주는 사례가 맣아지고 있다. 따라서 자동차에는 여러가지의 전장품, 전자기기를 탑재하기 때문에 자동차 자체에서 발생하는 것과 외부로 부터 받는 전자장해 EMI(Electromagnetic Interference), EMS(Electromagnetic Susceptibility) 가 문제로 되어 자동차 및 부품 maker에 의한 EMC(Electromagnetic Compatibility) 평가의 중요성이 고조되고 있다. 차제무전기, 차제무전기, Car-Radio는잡음방해를 많이 받기도 하지만, 잡음원이 되기 도 한다. 또한 Engine 제어, 차속제어, Brake 제어등에 이용되는 전자제품은 방해에 의한 오동작 또는 파괴가 발생하여 주행기능, 안전성에 문제가 야기되지 않도록 해야 한다. 이러한 전자기 환경은 모두 RF(Radio Frequence)와 자동차에서의 전자파 장해 문제의 원이 될 수 있다. 자동차 및 그 부품의 전자기 방해에 관한 규격화는 1987년부터 괄목할 만하게 진행되어 이에 따른 규제 움직임이 IEC(International Electrotechnical Commission: 국제전기기술위원회) 산하의 하부기 구인 CISPR(International Special Committeeon Radio Interference: 국제 무선 장해 특별위원회)가 전자기 방해파에 대한 측정법 통일안을 제안 하였고, ISO(International Standardization Organiza- tion: 국제표준화 기구) 가운데 TC 22/SC3가 자동차의 전장품에 대한 장해를 논의히고 있다. 특히, 자동차의 EMC에 관한 국가 규격은 국제 규격에서 저술한 바와 같이 특별히 규정된 것이 없고 VDE(Verband Deutscher Elektrotechniker: 서독전기기술 협회)와 SAE(Society of Automotive Engi- neers: 자동차 기술자 협회)에서 비교적 활발하고 Jaso(Japanese Automobile Standards Organization: 일본 자동차 표준협회)에서 많이 진행중에 있다. 본 고에서는 자동차의 전자제어에 따른 잡음 발생 요인과 전자파 간섭 관련 자동차 규격과 시험평가 방법에 대해 간단히 소개 하였다.

• Journal of the Korean Dietetic Association
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• v.11 no.3
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• pp.365-374
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• 2005

This study was conducted to compare the validity of obese index among body mass index(BMI), waist to hip ratio(WHR), and waist circumference(WC) and to determine which is the best in relation to cardiovascular risk factors of middle aged Korean(40-64yr).Data from the 1998 Korean Health and Nutrition Survey were used(N=3380). Anthropometric indices and cardiovascular risk factors were measured. Chi-square test, analysis of variance following duncan's multiple range test, partial correlation analysis, and Receiver Operator characteristic(ROC) curves were used in the analysis. There was a significant increasing trend in WHR, systolic blood pressure(SBP), high density lipoprotein cholesterol(HDL), and fasting blood sugar(FBS) with age categories of male and in BMI, WC, WHR, diastolic blood pressure(DBP), SBP, total cholesterol(TC), low density lipoprotein cholesterol(LDL), triglycerol(TG), and FBS with those of female. Specially female had the characteristics of upper body fat and systolic blood pressure risk(p<0.05). Proportions of subjects with lifestyle factors related to cardiovascular risk in overweight or upper body fat group were higher than that of normal group. Higher proportions of subjects were practiced exercise in upper body fat group of male than in other groups. Among 7 cardiovascular risk factors in partial correlation analysis, BMI had the highest correlation coefficient in 6 risk factors in male, whereas WC in 4 risk factors in female. Mean of each obese index according to cardiovascular risk groups except smoker was higher than that of normal(p<0.05). These trends were shown in upper body fat group and female. In ROC analysis of 12 risk factors and health conditions, the largest area under curve among obese indices for risk factors were BMI in male and WHR in female. The optimal cutoff values of each index(BMI: WHR: WC) for one or more cardiovascular risk factors were 23.13: 0.89: 85.35 in male and 23.57: 0.84: 78.35 in female. The results showed that cardiovascular risk factors were prevalent in middle aged Koreans within normal limits of obese indices like another Asians. For the identification of cardiovascular risk factors of middle aged Koreans, BMI for men and WHR for women are appropriate indices. But it is recommended that BMI, WHR, and WC, all three indices should be considered, when using these indices.