• Title/Summary/Keyword: TC&R

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Assessment of TC&R RF Test Result of LEO Satellite (저궤도 위성 TC&R RF 시험 결과에 대한 분석)

  • Cho, Seung-Won;Youn, Young-Su;Kwon, Jae-Wook;Kim, Young-Yun;Huh, Yun-Goo;Choi, Jong-Yeoun
    • Aerospace Engineering and Technology
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    • v.7 no.1
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    • pp.76-82
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    • 2008
  • The communication function and performance between low earth orbit satellite and ground should be verified by various TC&R RF test before the launch. In this paper, the procedure is examined from the preparation of the TC&R test to getting the results through measurement and the factors which should be measured to acquire reliable results is also described. Finally, it is verified that the results acquired through this procedure satisfy the requirement.

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Protective Effects of $\alpha$-Tocopherol and Ischemic Preconditioning on Hepatic Reperfusion Injury

  • Lee Woo-Yang;Lee Sun-Mee
    • Archives of Pharmacal Research
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    • v.28 no.12
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    • pp.1392-1399
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    • 2005
  • This study evaluated the effect of $\alpha$-tocopherol ($\alpha$-TC), ischemic preconditioning (IPC) or a combination on the extent of mitochondrial injury caused by hepatic ischemia/reperfusion (I/R). Rats were pretreated with $\alpha$-TC (20 mg/kg per day, i.p.) for 3 days before sustained ischemia. A rat liver was preconditioned with 10 min of ischemia and 10 min of reperfusion, and was then subjected to 90 min of ischemia followed by 5 h or 24 h of reperfusion. I/R increased the aminotransferase activity and mitochondrial lipid peroxidation, whereas it decreased the mitochondrial glutamate dehydrogenase activity. $\alpha$-TC and IPC individually attenuated these changes. $\alpha$-TC combined with IPC ($\alpha$-TC+IPC) did not further attenuate the changes. The mitochondrial glutathione content decreased after 5 h reperfusion. This decrease was attenuated by $\alpha$-TC, IPC, and $\alpha$-TC+IPC. The significant production of peroxides observed after 10 min reperfusion subsequent to sustained ischemia was attenuated by $\alpha$-TC, IPC, and $\alpha$-TC+IPC. The mitochondria isolated after I/R were rapidly swollen. However, this swelling rate was reduced by $\alpha$­TC, IPC, and $\alpha$-TC+IPC. These results suggest that either $\alpha$-TC or IPC reduces the level of mitochondrial damage associated with oxidative stress caused by hepatic I/R, but $\alpha$- TC combined with IPC offers no significant additional protection.

Characterization of Tetracycline-Resistant Genes of Staphylococci isolates from Human and Marine Environment (사람과 해양환경에서 분리된 Staphylococci의 Tetracycline 내성 유전자의 특성 비교)

  • CHO, Ki-Taek;KIM, Young-Chul;KWON, Woo-Ju;JEONG, Hyun-Do
    • Journal of Fisheries and Marine Sciences Education
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    • v.28 no.1
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    • pp.59-68
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    • 2016
  • For comparison of tetracycline-resistant ($Tc^R$) genes, we obtained 21 and 14 $Tc^R$ Staphylococcus spp. from marine environment and human patient, respectively. Although all isolates from human were identified as Staphylococcus aureus, higher proportion of $Tc^R$ isolates (12 out of 14) from human were utilizing tet(M) gene compared to that of $Tc^R$ isolates (6 out of 21) from marine environment. Additionally, collaborated utilization of tet(M) and erm(A) in $Tc^R-Em^R$ S. aureus in human patient, but not in $Tc^R$ Staphylococcus spp. isolates from marine environment was also characterized. Based on the nucleotide sequence of transposon related to $Tc^R$ gene, we confirmed the origin of tet(M) gene in $Tc^R$ Staphylococci isolated from marine environments and human are derived from Tn916/1545-like and Tn5801 transposon, respectively. It is the first report showing the presence of Tn5801 in all $Tc^R$ S. aureus carrying tet(M) in human patient. Alignment of the fully sequenced tet(M) from marine environmental isolates was also agreed with the determined transposons by showing the genomic mosaic structure composed with three genomic parts from Tn916/1545 and unknown transposons. Genetic characteristics of these tet(M) in environmental isolates were similar to each other but different from those in isolates from human showing only tet(M) from Tn916/5801 type. It may imply the presence of less dramatic communication of antibiotic resistant genes between Staphylococci isolated from marine environment and human.

Design of Cold-junction Compensation and Disconnection Detection Circuits of Various Thermocouples(TC) and Implementation of Multi-channel Interfaces using Them (다양한 열전쌍(TC)의 냉점보상과 단선감지 회로설계 및 이를 이용한 다채널 인터페이스 구현)

  • Hyeong-Woo Cha
    • Journal of IKEEE
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    • v.27 no.1
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    • pp.45-52
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    • 2023
  • Cold-junction correction(CJC) and disconnection detection circuit design of various thermocouples(TC) and multi-channel TC interface circuit using them were designed. The CJC and disconnection detection circuit consists of a CJC semiconductor device, an instrumentation amplifier(IA), two resistors and a diode for disconnection detection. Based on the basic circuit, a multi-channel interface circuit was also implemented. The CJC was implemented using compensation semiconductor and IA, and disconnection detection was detected by using two resistor and a diode so that IA input voltage became -0.42V. As a result of the experiment using R-type TC, the error of the designed circuit was reduced from 0.14mV to 3㎶ after CJC in the temperature range of 0℃ to 1400℃. In addition, it was confirmed that the output voltage of IA was saturated from 88mV to -14.2V when TC was disconnected from normal. The output voltage of the designed circuit was 0V to 10V in the temperature range of 0℃ to 1400℃. The results of the 4-channel interface experiment using R-type TC were almost identical to the CJC and disconnection detection results for each channel. The implemented multi-channel interface has a feature that can be applied equally to E, J, K, T, R, and S-type TCs by changing the terminals of CJC semiconductor devices and adjusting the IA gain.

Influence of Iodinated Magnetic Resonance Contrast Media and Isotope 99mTc on Changes of Computed Tomography Number

  • Kim, Sang-Beom;Lee, Jin-Hyeok;Ahn, Jae-Ouk;Cho, Jae-Hwan
    • Journal of Magnetics
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    • v.20 no.3
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    • pp.302-307
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    • 2015
  • The purpose of the study was to identify how isotope and magnetic resonance imaging (MRI) contrast media impact on noise to computed tomography (CT) examination. For the study, divide the phantoms to two groups: 1) saline, saline + different kinds of contrast agent without $^{99m}Tc$ administration; 2) $^{99m}Tc$ administration: saline, saline + different kinds of contrast agent with $^{99m}Tc$ administration. CT contrast agent was used for Iopamidol$^{(R)}$ and Dotarem. And MRI contrast agent was used for Primovist$^{(R)}$ and Gadovist$^{(R)}$. To obtain an image, we used CT scanner. With an obtained image, we set the $1cm^2$ region of interest in the middle of bottle to measure the noise and CT number. As a result, there was no difference in CT number before and after inserting $^{99m}Tc$ into all contrast media including Normal Saline. However, when it comes to Noise, there was a difference before and after inserting $^{99m}Tc$ into every contrast media except MRI contrast media such as Primovist$^{(R)}$ and Gadovist$^{(R)}$.

Distribution of R Factors in Salmonella and Escherichia Coli Isolated from Korean Domestic Animals (우리나라 가축(家畜)에서 분리(分離)한 Salmonella 및 대장균(大腸菌)의 내성인자(耐性因子) R의 분포(分布))

  • Ha, Tai-You;Chung, Sun-Sik;Kang, Byung-Kyu
    • The Journal of the Korean Society for Microbiology
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    • v.6 no.1
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    • pp.21-27
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    • 1971
  • Recent reports confirm that R factors is widespread in Korea among Enterobacteriaceae isolated from humans. However, no reports have been made concerning the incidence of transferable drug resistance in domestic animals in this country. A total of 211 isolates of Escherichia coli, including 94 strains from dogs, 76 strains from pigs, 30 strains from chickens, and 21 strains from cow milk, were examined for drug resistance and distribution of R factors. And, respective two strains of Salmonella E group and Salmonella cholerasuis which were isolated from dogs and pigs, respectively were also examined for the same purposes. Of 211 strains of E. coli isolated, 66.8% were found to be resistant to 8 antibacterial agents such as streptomycin(SM), tetracycline(TC), chloramphenicol(CP), ampicillin sodium(AP), nalidixic acid(NA), gentamicin(GM), and polymyxin B(PX). Among the isolates, 86.2% of the strains from dogs, 70% of the strains from chickens, 43.4% of the strains from pigs, and 28.6% of the strains from milk, respectively, were found to be resistant to the drugs. The following percentage of resistance of E. coli to each individual drugs was encountered: of 94 strains from dogs, AP, 64.9%; SM, 20.2%; NA, 12.8%, CP and PX, 8.5% each; GM, 2.1% each; GM, 2.1%. Among 76 strains from pigs, 42.2% and 2.6% each were resistant to TC, AP and PX, respectively. Among 30 strains from chickens, 43.3% were resistant to SM, TC, AP, respectively, and no strains were resistant to the other drugs. No strains of the isolated from milk were resistant to the drugs, except that 28.6% were resistant to SM and AP, respectively. Of the strains from dogs, multiply resistant strains(56.8%) were more than singly resistant one(43.2%) and sixteen different drug resistant patterns were observed. The most frequently encountered patterns were AP TC AP and SM CP AP NA. Of the isolates from other sources, the most frequently encountered resistant patterns were as follows: TC among the strains from pigs; SM TC AP from chickens; SM AP from milk. Of the resistant strains from dogs, 32% carried R factors and the most common resistance patterns of R factors were AP TC AP and SM TC CP, whereas 35.2% of the resistant strains from pigs carried R factors of which the most common encountered pattern was TC. Of the resistant strains from chickens, 46.9% carried R factors of which the most common patterns were SM TC TC AP and AP, whereas 50% of the resistant strains from milk carried R factors of which the most common pattern was SM. Of 4 strains of Salmonella isolated, no strains were resistant to the drugs, except that only one strain of Salmonella E group isolated from a dog was resistant to AP. The strain did not harbor R factor.

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Antimicrobial Susceptibility of Salmonella and Shigella Isolated in Taegu Area in 1977 (1977년(年) 대구(大邱)에서 분리(分離)한 Salmonella 및 Shigella의 항균제(抗菌劑) 감수성(感受性))

  • Park, Moon-Jae;Chun, Do-Ki
    • The Journal of the Korean Society for Microbiology
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    • v.13 no.1
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    • pp.31-36
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    • 1978
  • Twenty strains of Salmonella paratyphi A, 55 of S. typhi, 7 of Shigella flexneri, and 14 of Sh. sonnei which were isolated in Taegu area in 1977, were tested for the susceptibility to antimicrobial drugs. All strains of S. paratyphi A were resistant to sulfisomidine(Sa), but none was resistant to chloramphenical(Cm), tetracycline(Tc), streptomycin(Sm), ampicillin, nalidixic acid, kanamycin, gentamicin, amikacin, 1:20 mixture of trimethoprim and sulfamethoxazole, carbenicillin, cephaloridine, and rifampicin. Only one strain. of S. typhi was multiply resistant to Cm, Tc, Sm, and Sa, but all strains were susceptible to the other drugs tested. The resistant strain carried R plasmid; R(Cm Tc Sm Sa). All strains except one were highly resistant to Cm, Tc, Sm, and Sa, and all except one of multiply resistant strains carried R plasmid; R(Cm Tc Sm Sa).

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Analysis on Relations between Travel time and Watershed Characteristics (유역특성(流域特性)과 홍수도달시간(洪水到達時間)과의 상관해석(相關解析))

  • Suh, Seung Duk;Lim, Kyu Dong
    • Current Research on Agriculture and Life Sciences
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    • v.5
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    • pp.158-167
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    • 1987
  • The purpose of this study is to inquire and analyse the relation between traveltime (Tc) and watetshed physical characteristics surveyed such as river length (L), Lea, river main slope (s), base length of time area diagram, and storage constant (k). The results obtained in this study are as follows. The average widths of watersheds were with the range from 4.6 kilometers to 16.7 kilometers. The shape factors of main stream ranged from 0.08 to 0.37. The average slopes to main 8tream were within the range of 1.7-5.5 meter per kilometer. The relation between the base length and traveltime from S. C. S. method, Rational method, and RZIHA+KRAVEN method were derived $Tc=0.524{\times}1.35^c$ (r=0.98), $Tc=0.628{\times}1.339^c$, (r=0.98), $Tc=0.667{\times}1.342^c$ (r=0.97). The base length of the time-area diagram (c) for the IUH was derived as $c=0.9(\frac{L.L_{ca}}{\sqrt{s}})^{0.35}$ and correlation coefficient was 0.98 which defined a high significance. The storage constant K, derived in this study was $K=8.32+0.0213{\frac{L}{\sqrt{s}}}$ with correlation coefficient (0.96). The relation between storage Constant and conventional formula were figured out $Tc=0.0003{\times}3.323^k$ (r=0.97). $Tc=0.00045{\times}3.268^k$ (r=0.99) and $Tc=0.0004{\times}3.26^k$ (r=0.963). The base length (c) and storage constant (k) of time-Area Diagram were very important parts that determined traveltime for flood events. In the estimate of travel time for predicting flood volume, the formula of $Tc=0.524{\times}1.35^c$ that would be available to apply the Nak - Dong river watershed area and homogeneous watershed characteristics was found.

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Antibiotic Resistance of Escherichia coli Isolated from Hens (계유내(鷄由來) Escherichia coli의 항생물질내성(抗生物質耐性)및 R 인자(因子)의 분포(分布))

  • Tak, Ryunbin
    • Korean Journal of Veterinary Research
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    • v.17 no.1
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    • pp.1-4
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    • 1977
  • Two hundred and twenty-seven strains of Escherichia coli isolated from 25 hens (12 hens received tetracycline neomycin and sulfadimethoxine, and 13 hens not received antibiotics) were studied for the drug resistance and distribution of R factors. About 74 per cent of E. coli strains isolated from hens of a herd received antibiotics were resistance to tetracycline (TC) streptomycin (SM), chloramphenicol (CM), kanamycin (KM), ampicillin (AP) and sulfisomidine (Su), alone or in combination thereof, but only a hen among a herd not received antibiotics excreted E. coli resistant to TC and SM. Among resistant strains, about 7% were found to be resistant to TC and SM, whereas 93% were resistant to three or more antibiotics. The most common pattern was the quadruple resistant to SM, TC, KM and Su (28.7%), and followed by triple ones to SM, TC and Su (25.3%), and SM, TC and KM (24.7%). About 84% of resistant strains carried R factors which were transferable to the recipient by conjugation.

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Lung/Heart Uptake Ratio in Dipyridamole $^{99m}Tc-MIBI$ Myocardial Perfusion Scan in Coronary Artery Disease (관상동맥질환에서 디피리다몰 부하 $^{99m}Tc-MIBI$ 심근스캔의 폐/심장 섭취율)

  • Kang, Keon-Wook;Lee, Dong-Soo;Choi, Chang-Woon;Lee, Kyung-Han;Chung, June-Key;Lee, Myung-Chul;Seo, Jung-Don;Koh, Chang-Soon
    • The Korean Journal of Nuclear Medicine
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    • v.27 no.2
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    • pp.218-222
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    • 1993
  • Lung/heart uptake ratio (L/H R) in $^{201}Tl$ myocardial perfusion scan is a reliable marker for long-term prognosis in patients with coronary artery disease. However, the value of L/H R in $^{99m}Tc-MIBI$ myocardial perfusion scan is controversial in determining the prognosis and severity of the coronary artery disease. The purpose of this study was to determine the clinical implications of L/H R in $^{99m}Tc-MIBI$ myocardial perfusion scan. Forty five patients who received $^{99m}Tc-MIBI$ myocardial perfusion scan were divided into control group and coronary artery disease (CAD) group by their clinical findings, EKGs, and $^{99m}Tc-MIBI$ myocardial perfusion scans. Twenty five patients in CAD group were divided into ischemic group and infarct group according to their results from $^{99m}Tc-MIBI$ myocardial perfusion scan. L/H R was calculated on the anterior planar view, 60 minutes after infusion of dipyridamole. Two regions of interest (ROI) were placed on the left lung area 8 pixel above the left ventricle and on the myocardial area which had the highest radioactivity. In the control group, there were no significant differences of L/H R according to sex and age. No significant difference of L/H R was found between the control and CAD group ($0.26{\pm}0.06,\;0.29{\pm}0.05$, p>0.05). In the CAD group, there was also no significant difference of L/H R between the ischemic group and infarct group ($0.29{\pm}0.07,\;0.30{\pm}0.04$, p>0.05). L/H R in CAD group did not show correlations with the defect area of stress polar map (r=0.18, p >0.05) and with the sum of severity weighted extent score or reversibility score which represent severity and extent of myocardial perfusion defect area in stress (r=0.18, p>0.05). We conclude that it is difficult to use L/H R as a marker for severity of CAD in dipyridamole $^{99m}Tc-MIBI$ myocardial perfusion scan.

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