• 한국수정란이식학회지
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• 제30권4호
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• pp.277-282
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• 2015

Cryopreservation affects osmotic tolerance and intracellular ion concentration through changes in expression levels of water and ion channels. Control of these changes is important for cell survival after cryopreservation. Relatively little is known about changes in $K^+$ channel expression compared to water channel expression. This study was performed to investigate changes in TASK-2 channel (KCNK5: potassium channel, subfamily K, member 5), a member of two-pore domain $K^+$ channel family, in cryopreserved mouse ovaries. Cryopreservation increased TASK-2 mRNA expression in mouse ovaries. In addition, TASK-2 protein expression was upregulated in vitrified and slowly frozen ovaries. TASK-2 protein was expressed in all area of granulosa cells that surround the oocyte within the follicle, except nucleus. Viability of cells overexpressed with TASK-2 was higher than that of vector-transfected cells. Our results found that TASK-2 expression was increased by cryopreservation and overexpression of TASK-2 decreased cryopreservation-induced cell death. These results suggest that TASK-2 upregulation might reduce cryodamage.

• 대한인간공학회지
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• 제23권2호
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• pp.25-36
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• 2004

The effects of task characteristics on the relative efficiency of visual display dimension were studied using a simulated tele-robotic task. Through a conventional method of task analysis. the tele-robotic task was divided into two categories: the task element requiring focused attention (FA task) and the task element requiring global attention (CA task). Time-ta-completion data were collected for a total of 120 trials involving 10 participants. For the CA task. there was no significant difference between the multiple two-dimensional (20) display and the three-dimensional (3D) monocular display. For the FA task. however. the multiple 20 display was superior to the 3D monocular display. The results suggest that the characteristics of a given task have a considerable effect on the choice of display dimensionality and the multiple 3D display is better for human operators to effectively judge depth if the task requires frequent use of focused attention.

• 가정과삶의질연구
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• 제18권2호
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• pp.109-123
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• 2000

The purpose of this study is to investigate decision making styles task management of urban homemakers. This study focuses on the following aspects: 1) to find out which variables of background variables (ie. age of couple, education of couple, duration of marriage, income, family life cycle, number of children) have effect on decision making styles & task management of urban homemakers. 2) to find out the relationships between decision making styles and task management of urban homemakers. 3) to find out independent influcene of background variables on task management. major findings are as follows; First, it is general tendency that decision making styles were human oriented in urban homemakers. Importance & Urgency of the task, age of homemakers, education of homemakers, family life cycle were significant variables to have influcence on task oriented decision making styles. Importance & urgency of task were variables to have influences on human oriented decision making styl s. Second, the tendency of dealing with task at once is the highest in the task management, on the other hand, the tendency of dealing with task in the next session is the lowest. Income is a variable to influence on dealing with task in delegation to others, education of homemaker is a variable to influence on dealing with task in next session and importance & urgency of the task and the number of children were variables to influence on dealing with task immediately. Third, human oriented decision marking style was a variable to influence on dealing with task in delegation with task in delegation to others, in the next session, and in suspending/ in neglecting. Task oriented decision making style was a variable to influence on dealing with task immediately. Fourth, The urgency of task & income were variables to have direct influence on dealing with task in delegation with task in next session, and the urgency of the task, age & education of homemaker and family life cycle were varia les to direct influence on dealing with the task immediately. The urgency & importance of the task and age of homemaker were variables to have indirect on dealing with the task urgency of task & the number of children were variables to have indirect influence on dealing with the task in suspending/in neglecting through the medium of the human oriented decision making styles.

• 대한물리의학회지
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• 제11권2호
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• pp.83-91
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• 2016

PURPOSE: The purpose of this study was to determine the efficacy of dual-task action observation training (AOT) and single-task AOT related with daily living task on walking ability and ADL performance in chronic stroke patients. METHODS: Twenty-seven chronic stroke subjects were included in the study. They were randomly assigned to three task categorieds as follows: whole dual-task AOT or partial dual-task AOT or single-task AOT rehabilitation. Whole dual-task AOT observed the movement at once and partial dual-task AOT observed the movement divided into 4 parts related functional gait and activities of daily living task for 2 minutes 30 seconds. Single-task AOT observed the movement related functional gait for 2 minutes 30 seconds. Both groups had physical training session for 12 minutes 30 seconds. The study was conducted for four weeks, with three training sessions a week, for twelve weeks. All subjects were evaluated for their walking ability and activities of daily living through devices, 10m walking test (10MWT), dynamic gait index (DGI), and Korea-Modified Barthel Index (K-MBI). RESULTS: A significant improvement of walking ability and ADL performance happened among dual-task AOT subjects, compared with a single-task AOT subjects, during the 4-weeks course treatment. The results of the study showed statistically significant differences in 10MWT (p<0.05) and DGI (p<0.05), and K-MBI (p<0.05). CONCLUSION: Our results indicated that dual-task AOT has a positive additional impact on recovery of walking ability and ADL performance in chronic stroke patients.

• 재활치료과학
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• 제6권2호
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• pp.71-83
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• 2017

Objective: This study was to develop and verify the effects of the exercise-cognitive combined dual-task training program on cognitive function and depression of the elderly with mild cognitive impairment(MCI). Methods: The subjects were randomly assigned to the exercise-cognitive combined dual-task training group(n=32) or single-task training group(n=31). To identify the effects on cognitive function, general cognitive function, frontal lobe function, and attention/working memory were measured. Depression was evaluated using Korean version of Geriatric Depression Scale. The outcome measurements were performed before and after the 8 weeks of intervention(2 days per week). Results: After 8 weeks, general cognitive function, frontal cognitive function, attention/working memory function, depression of the dual-task training group were significantly increased than those of the single-task training group(p<0.05). Conclusion: The results indicated that an exercise-cognitive combined dual-task training for MCI was effective in improving general cognitive function, frontal /executive function, attention/working memory function and reducing depression.

• ETRI Journal
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• 제36권5호
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• pp.704-713
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• 2014

Most natural language processing tasks depend on the outputs of some other tasks. Thus, they involve other tasks as subtasks. The main problem of this type of pipelined model is that the optimality of the subtasks that are trained with their own data is not guaranteed in the final target task, since the subtasks are not optimized with respect to the target task. As a solution to this problem, this paper proposes a consolidation of subtasks for a target task ($CST^2$). In $CST^2$, all parameters of a target task and its subtasks are optimized to fulfill the objective of the target task. $CST^2$ finds such optimized parameters through a backpropagation algorithm. In experiments in which text chunking is a target task and part-of-speech tagging is its subtask, $CST^2$ outperforms a traditional pipelined text chunker. The experimental results prove the effectiveness of optimizing subtasks with respect to the target task.

• 중환자간호학회지
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• 제6권1호
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• pp.34-43
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• 2013

Purpose: This study was conducted to examine the relationship among task interruption, task performance, and burn-out in nurses working at emergency room. Methods: The subjects of this study were 225 working at emergency rooms of 19 hospitals. Data was collected by using the structured questionnaire, including frequency of task interruption. problems in task performance due to interruption, and burn-out. Results: The average scores of task interruption were 2.06 due to communication, 1.49 due to treatment and record, and 1.39 due to other services (range 1-4). Frequency of task interruption was significantly correlated with task performance and burn-out. Conclusion: Emergency room nurses experienced some task interruption. The task interruption can influence upon task performance and burn-out of emergency room nurse.

• The Korean Journal of Physiology and Pharmacology
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• 제9권1호
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• pp.63-68
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• 2005

Hydrogen peroxide ($H_2O_2$) causes oxidative stress and is considered as an inducer of cell death in various tissues. Two-pore domain $K^+$ ($K_{2p}$) channels may mediate $K^+$ efflux during apoptotic volume decreases (AVD) in zygotes and in mouse embryos. In the present study, we sought to elucidate linkage between $K_{2p}$ channels and cell death by $H_2O_2$. Thus $K_{2p}$ channels (TASK-1, TASK-3, TREK-1, TREK-2) were stably transfected in HEK-293 cells, and cytotoxicity assay was preformed using cell counting kit-8 (CCK-8). Cell survival rates were calculated using the cytotoxicity assay data and dose-response curve was fitted to the $H_2O_2$ concentration. Ionic currents were recorded in cell-attached mode. The bath solution was the normal Ringer solution and the pipette solution was high $K^+$ solution. In HEK-293 cells expressing TREK-1, TREK-2, TASK-3, $H_2O_2$ induced cell death did not change in comparison to non-transfected HEK-293. In HEK-293 cells expressing TASK-1, however, dose-response curve was significantly shifted to the left. It means that $H_2O_2$ induced cell death was increased. In cell attached-mode recording, application of $H_2O_2$ (300μM) increased activity of all $K_{2p}$ channels. However, a low concentration of $H_2O_2$ ($50{\mu}M$) increased only TASK-1 channel activity. These results indicate that TASK-1 might participate in $K^+$ efflux by $H_2O_2$ at low concentration, thereby inducing AVD.

• 로봇학회논문지
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• 제14권2호
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• pp.104-113
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• 2019

Object manipulation in cluttered environments remains an open hard problem. In cluttered environments, grasping objects often fails for various reasons. This paper proposes a novel task and motion planning scheme to grasp objects obstructed by other objects in cluttered environments. Task and motion planning (TAMP) aims to generate a sequence of task-level actions where its feasibility is verified in the motion space. The proposed scheme contains an open-loop consisting of three distinct phases: 1) Generation of a task-level skeleton plan with pose references, 2) Instantiation of pose references by motion-level search, and 3) Re-planning task based on the updated state description. By conducting experiments with simulated robots, we show the high efficiency of our scheme.

• Physical Therapy Rehabilitation Science
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• 제1권1호
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• pp.1-5
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• 2012

Objective: Dual-task walking deficits impact functional daily life, which often requires walking while performing simultaneous tasks such as talking, thinking or carrying an object. This study is to find out the latest trend of dual-task training's influence on ambulatory abilities of a stroke patient. Design: Systematic review of randomized controlled trials. Methods: This literature review was conducted in Pubmed and Sciencedirect with the follwing key words:stroke, cerebro-vascular accident, hemiplegia, gait, rehabilitation, exercise. 7 studies were chosen in findings by search tool. 3 studies were case study, 3 studies were cross sectional observational study and 1 study was randomized controlled trial. Results: It was found that stroke patients have difficulties in doing 2 motor tasks simultaneously and when they do 2 tasks, one is done in a naturally preferred activity areas. Moreover, when simply applying dual-tasks, the walking speed decreased. Meanwhile, when applying them through training, the speed increased. This showed the improvement of effective task-implementation abilities after dual-task training using task-integration models. Conclusions: In the beginning of the 2000s, dual-tasks were implemented by simply combining walking and cognition or exercise task, and the results of this study suggest that subjects with stroke have difficulty performing dual task. However, the latest trend is to let patients do the dual-task training by combining it with virtual reality. Therefore, dual task training could be performed in a safe in the environment such as virtual reality or augment reality.