• 한국통신학회:학술대회논문집
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• 한국통신학회 2006년도 하계종합학술발표회 논문 초록집
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• pp.204-204
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• 2006

• 생명과학회지
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• 제28권8호
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• pp.992-998
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• 2018

암세포는 종양의 성장을 지지하는 다양한 성분으로 구성되어 있는 환경에서 자란다. 암미세환경에 존재하는 주요 세포등은 섬유아세포, 내피세포, 면역세포들이며 이들세포들은 암세포들과 서로 소통을 하고 있다 종양조직에 유입된 면역세포중에서 대식세포가 종양미세환경의 주요성분으로서 다양한 면역현상들을 조절한다. 면역세포유입에 의한 암촉진과 항암효과 간의 복잡한 균형은 종양의 성장과 진행에 필요한 만성염증 환경을 생성시킬 수 있다. 대식세포는 M1과 M2 극성화로 규정된 미세환경 신호에 반응하여 기능적으로 다른 프로그램을 작동시킬 수 있다. 종양관련대식세포는 다양한 사이토카인, 케모카인, 단백질분해효소들을 분비함으로써 암 신생혈관형성, 증식, 전이 및 면역억제를 촉진시킨다. 최근에, 종양관련대식세포는 암줄기세포와 상호작용하여 종양의 진행, 전이 및 항암제 내성을 유도하는 것으로 알려져 있다. 종양관련대식세포는 암미세환경을 유지하기위해 면역억제 기능을 획득하며, 종양의 이질성과 가소성의 특성을 갖고 있어 암관련인자 및 감염등의 노출에 의해 서로 다른 극성형질로 리프로그래밍된다. 종양관련대식세포는 기질인자의 자극에 의해 암특이적인 케모카인들을 생성하기 때문에 케모카인은 질병의 활성을 반영하는 바이오마커로 작용할 수 있다. 종양조직에 종양관련대식세포가 많이 유입될수록 환자의 예후가 좋지 않으며 항암치료에 대한 저항성이 생긴다. 따라서 종양에서 대식세포를 표적화하는 항암치료는 유망한 치료전략이 될 수 있다.

• Asia pacific journal of information systems
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• 제19권2호
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• pp.73-94
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• 2009

The general aspects for the future warfare shows that the concept of firepower and maneuver centric warfare has been replacing with that of information and knowledge centric warfare. Thus, some developed countries are now trying to establish the information systems to perform intelligent warfare and innovate defense operations. The C4I(Command, Control, Communication, Computers and Intelligence for the Warrior) systems make it possible to do modern and systematic war operations. The basic idea of this study is to investigate how TAM(Technology Acceptance Model) can explain the acceptance behavior in military organizations. Because TAM is inadequate in explaining the acceptance processes forcomplex technologies and strict organizations, a revised research model based upon TAM was developed in order to assess the usage of the C4I system. The purpose of this study is to investigate factors affecting the usage of C4I in the Korean Army. The research model, based upon TAM, was extended through a belief construct such as self-efficacy as one of mediating variables. The self-efficacy has been used as a mediating variable for technology acceptance, and the variable was included in the research model. The external variables were selected on the basis of previous research. The external variables can be classified into following: 1) technological, 2) organizational, and 3) environmental factors on the basis of TOE(Technology-Organization-Environment) framework. The technological factor includes the information quality and the task-technology fitness. The organizational factor includes the influence of senior colleagues. The environmental factor includes the education/train data. The external variables are considered very important for explaining the behavior patterns of information technology or systems. A structured questionnaire was developed and administrated to those who were using the C4I system. Total 329 data were used for statistical data analyses. A confirmatory factor analysis and structured equation model were used as main statistical methods. Model fitness Indexes for measurement and structured models were verified before all 18 hypotheses were tested. This study shows that the perceived usefulness and the self-efficacy played their roles more than the perceived ease of use did in TAM. In military organizations, the perceived usefulness showed its mediating effects between external variables and dependent variable, but the perceived ease of use did not. These results imply that the perceived usefulness can explain the acceptance processes better than the perceived ease of use in the army. The self-efficacy was also used as one of the three mediating variables, and showed its mediating effects in explaining the acceptance processes. Such results also show that the self-efficacy can be selected as one possible belief construct in TAM. The perceived usefulness was influenced by such factors as senior colleagues, the information quality, and the task-technology fitness. The self-efficacy was affected by education/train and task-technology fitness. The actual usage of C4I was influenced not by the perceived ease of use but by the perceived usefulness and selfefficacy. This study suggests the followings: (1) An extended TAM can be applied to such strict organizations as the army; (2) Three mediation variables are included in the research model and tested at real situations; and (3) Several other implications are discussed.

• 한국식품과학회지
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• 제47권2호
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• pp.191-197
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• 2015

본 연구는 국내에서 주로 판매되고 있는 망고 품종의 이화학적 특성과 망고의 휘발성 향기성분의 화합물 조성을 비교하였다. 품종이 다른 대만 산 애플 망고와 필리핀 산 카라바오 망고의 조회분을 제외한 일반성분은 대부분 유의한 차이를 보였고, 수분과 조지방은 애플 망고에서 높았으며, 조단백과 탄수화물은 카라바오 망고에서 높았다. 유리당 함량은 두 품종에서 sucrose, fructose, glucose의 순으로 높게 검출되었으나 함량에서는 유의적 차이를 보였다. 그러나 maltose, lactose, galactose는 검출되지 않았다. SPME 추출법으로 확인된 휘발성 향기성분은 대만 산 애플 망고, 필리핀 산 카라바오 망고에서 각각 56종, 59종을 확인할 수 있었고, 휘발성 향기성분을 분석한 함량은 각각 59.45, 37.25%이 추출되었다. 휘발성 향기성분의 종류 및 함유량에서 테르펜류 및 그 유도체의 종류 및 함유량 모두가 높았고 ester류 화합물이 다음으로 높았으며 함유량에서는 품종에 따라 차이를 보였다. 테르펜류와 그 유도체 함유량은 대만 산 애플 망고에서 94.42%로 높게 나타나는 특징을 보였고, 필리핀 산 카라바오 망고에서는 63.79%로 차이를 보였다. 필리핀 산 카라바오 망고는 acetic acid, hexanoic acid, octanoic acid, palmitic acid 등의 acid류 화합물이 품종이 다른 대만 산 애플 망고의 휘발성 향기성분과 비교하여 종류 및 함유량에서 높게 나타나는 특징을 보였다. 대만 산, 필리핀 산 망고 모두에서 ${\delta}$-3-carene의 함량이 각각 17.78, 8.11%로 확인되어 동정된 화합물 중 가장 높은 함량을 보였다. 대만 산애플 망고의 경우 ${\alpha}$-copaene, ${\alpha}$-guaiene, germacrene D, ${\alpha}$-bulnesene, ${\gamma}$-gurjunene 등이, 필리핀 산 카라바오 망고는 ${\beta}$-myrcene, ${\alpha}$ 및 ${\beta}$-phellandrene, ${\alpha}$-terpinolene, cis-3-hexenyl butyrate 등이 특징적인 화합물로 확인되어 이는 품종에 따른 망고 향기성분의 특징을 구분하는데 기여할 것으로 생각된다.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제10권8호
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• pp.3972-3985
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• 2016

Organizations have been implementing mobile applications that actually connect to their backend enterprise applications (e.g. ERP, SCM, etc.) in order to increase the enterprise mobility. However, most of the organizations are still struggling to fully satisfy their mobile application users with the enterprise mobility. Even though it has been regarded as the right direction that the traditional enterprise system should move on, the studies on the success model for mobile enterprise applications in user's acceptance perspective can hardly be found. Thus, this study focused not only to redefine the success of the mobile enterprise application in user's acceptance persepective, but also to find the impacts of the factors on user's usage behavior of the mobile enterprise applications. In order to achieve this, we adopted the Technology Acceptance Model 2 (TAM2) as a model to figure out the user's behavior on mobile applications. Among various mobile enterprise applications, this study chose mobile ERP since it is the most representing enterprise applications that many organizations have implemented in their backend. This study found that not all the constructs defined by Davis in TAM2 have a significant influence on user's behavior of the mobile-ERP applications. However, it is also found that most social influence processes of TAM2 influence user's perception of the degree of interaction by mobile-ERP applications.

• 경영과학
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• 제21권1호
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• pp.1-17
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• 2004

A separate and distinct interaction with both the actual e-vendor and with its IT web site interface is at the heart of online shopping. Previous research has established, accordingly, that online purchase intention is the product of customer assessments of IT itself, specifically its perceived usefulness and ease-of-use(TAM). Since perceived usefulness and perceived ease of use are such a fundamental driver of usage intentions, it is important to understand the determinants of this construct and how their influence changes over the voluntariness towards the usage intention. The reason for voluntariness as a moderating variable is that it had the serious effect to the motivating in the making willingness of the internet shopping-mall usage. A better understanding of the determinants of perceived usefulness and perceived ease of use to the usage intention would enable us to design web site interventions that would increase user acceptance and usage of internet shopping-mall. Therefore, the goal of the present research is to extend TAM to include additional key determinants of TAM and to understand how the effects of these determinants change with the voluntariness of the usage intention of the internet shopping-mall.

• 경영과학
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• 제19권2호
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• pp.25-39
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• 2002

This study suggests a revised TAM (Technology Acceptance Model)-based performance evaluation model in MS (management science) education. Recently, many MS education programs are developed on the basis of computer and Internet communication technology. Previous researchers used TAM as an individual performance evaluation model, and proved that perceived usefulness and perceived ease of use are the substantive successful factors. This study provides a revised TAM-based conceptual framework for understanding what is involved in improving university MS education and what might be implied by conducting research on its improvement. It is argued in this research that three sets of forces and conditions have a direct and indirect impact on MS education ; first, each student has self efficacy and it is a critical determinant of behavior next, the use of Internet-based information system at MS education affects on the renewal of MS education : and finally, perceived usefulness and perceived ease of use have impacts on behavioral intention and actual system usage. This research concludes with suggestions for which direction this framework provides for future research on the premise and limits of efforts to renew MS education in university.

• 한국산학기술학회논문지
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• 제10권6호
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• pp.1191-1195
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• 2009

본 논문에서는 스캔 체인의 레이아웃 거리를 고려한 효율적인 Test Wrapper 설계 방식을 제안한다. SoC내의 스캔체인들을 태스트하기 위해서는 외부 TAM 라인(line)에 각 스캔체인들을 할당해야 한다. IP 내에 존재하는 스캔체인들은 정상모드에서는 타이밍 위반(Timing Violation)이 발생하지 않도록 레이아웃이 되지만, 테스트 모드에서는 TAM 라인(line)과 연결되는 스캔체인들 간에 부가적인 레이아웃 거리를 갖게 되므로 스캔체인에서 타이밍 위반이 발생될 수 있다. 본 논문에서는 타이밍 위반이 발생하지 않도록 체인간 레이아웃거리를 고려하여 스캔체인을 할당하는 새로운 test wrapper 설계 방식을 제안하였다.

• 한국의류산업학회지
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• 제18권1호
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• pp.38-47
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• 2016

This research analyzes the influence of mobile commerce characteristics on consumer's purchase intention using a theoretical Technology Acceptance Model (TAM) constructed on previous studies and a review of the literature to explain the effect of mobile fashion shopping characteristics on consumer's purchase intention. In constructing structural equation model, Mobile commerce characteristics variables such as 'security', 'enjoyment', and 'personalization' were selected as external variables affecting TAM. A questionnaire was distributed to consumers in their 20's-30's who had purchased fashion products using a mobile shopping channel. Statistical methods of confirmatory factor analysis, correlation, and covariance structural analysis using Amos 19.0 package were employed for the analysis of 453 effective data responses. The results were as follows. First, extended TAM was shown be the appropriate model to explain the influence of mobile commerce characteristics on consumer's purchase intention in mobile fashion shopping. Second, 'security' had a significant positive influence on perceived usefulness (PU), however it affected perceived ease of use (PEOU) negatively. Third, 'enjoyment' had a significant influence only on PEOU, while 'personalization' was found to affect both PEOU and PU significantly. Fourth, PEOU affected PU significantly. Finally, both PEOU and PU had a significant influence on consumer's purchase intention.

• 복식
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• 제58권6호
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• pp.145-157
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• 2008

Vivienne Tam was born in mainland China and educated in Hong Kong and has worked mainly in New York. Within multi-cultural background, she has shown unique fashion designs where western styles and China esprit were harmonized.. This study analyzed the ethnic look featured on Vivienne Tam's design to identify how she has expressed her ethnic identity into fashion. Photos featuring ethnic appeal among her New York collection from 1996 S/S to 2005 F/W were analyzed in terms of shape/silhouette, color, fabric, motifs, detail and accessaries. She utilized frequently chinese motifs and patterns such as bamboo, panda, budha, flowers, letters, and masks. Secondly she modified the shapes of Chinese traditional costume like Quipao to render ethnic appeal. Color, fabric and detail like frog and embroidery also contributed to enhance China mood. Comparatively, she used western clothing items including shirts, blouses, skirts, pants, dresses, and coats and maintained the silhouette tight and fit so that most her designs look wearable and westernized.